|
|
skeletal system development
|
GO:0001501 |
356 |
0.898
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.897
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.813
|
Mouse Fly |
|
|
regionalization
|
GO:0003002 |
337 |
0.669
|
Zebrafish Mouse Fly |
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.637
|
Mouse |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.568
|
Zebrafish Mouse Fly |
|
|
neural tube development
|
GO:0021915 |
160 |
0.557
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.557
|
Fly |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.506
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.482
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.460
|
Zebrafish Mouse |
|
|
t cell activation
|
GO:0042110 |
289 |
0.459
|
Mouse |
|
|
endocrine system development
|
GO:0035270 |
98 |
0.458
|
Mouse |
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.449
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.440
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.434
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.420
|
Zebrafish Mouse Fly |
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.417
|
Mouse |
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.410
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.409
|
Mouse |
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.398
|
Fly |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.393
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.387
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.381
|
Worm |
|
|
negative regulation of necroptotic process
|
GO:0060546 |
9 |
0.353
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.347
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.334
|
Mouse |
|
|
trunk segmentation
|
GO:0035290 |
4 |
0.329
|
Fly |
|
|
mesoderm development
|
GO:0007498 |
100 |
0.326
|
Mouse |
|
|
neural tube formation
|
GO:0001841 |
108 |
0.326
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.325
|
Mouse Fly |
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.322
|
Mouse |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.311
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.311
|
Mouse |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.310
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.306
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.303
|
|
|
|
neural crest cell differentiation
|
GO:0014033 |
54 |
0.301
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.296
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.294
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.293
|
Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.292
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
83 |
0.279
|
Mouse |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.278
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.275
|
Mouse |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.271
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.261
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.254
|
Zebrafish Mouse Fly |
|
|
somitogenesis
|
GO:0001756 |
69 |
0.252
|
Mouse |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.249
|
Fly |
|
|
tube formation
|
GO:0035148 |
140 |
0.243
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.241
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.239
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.234
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.232
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.231
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.224
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.223
|
Zebrafish Mouse Fly |
|
|
epidermis development
|
GO:0008544 |
187 |
0.221
|
Mouse |
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.217
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.212
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.206
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.206
|
|
|
|
endocardial cushion formation
|
GO:0003272 |
13 |
0.204
|
Mouse |
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.204
|
|
|
|
negative regulation of ripoptosome assembly involved in necroptotic process
|
GO:1902443 |
3 |
0.204
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.204
|
Mouse |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.201
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.196
|
Mouse |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.195
|
Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.193
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
26 |
0.190
|
Mouse Fly |
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.190
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.189
|
Zebrafish Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.188
|
Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.188
|
Zebrafish Mouse |
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.187
|
Mouse Fly |
|
|
segmentation
|
GO:0035282 |
93 |
0.187
|
Mouse Fly |
|
|
tube closure
|
GO:0060606 |
91 |
0.186
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.186
|
Mouse |
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.185
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.184
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
27 |
0.184
|
Mouse |
|
|
cell fate specification
|
GO:0001708 |
72 |
0.184
|
Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.180
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.176
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.175
|
Worm Fly |
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.174
|
Mouse |
|
|
gastrulation
|
GO:0007369 |
116 |
0.173
|
Zebrafish Mouse Fly |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.173
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.172
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.171
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.170
|
Zebrafish Mouse |
|
|
appendage development
|
GO:0048736 |
166 |
0.169
|
Fly |
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.168
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.168
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.166
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.165
|
|
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
11 |
0.164
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
50 |
0.164
|
Mouse |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.164
|
Mouse |
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.163
|
Mouse |
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.163
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.162
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.161
|
Mouse |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.160
|
Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.158
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.155
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.153
|
Mouse |
|
|
amide transport
|
GO:0042886 |
138 |
0.153
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.152
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.151
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.150
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.148
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.148
|
|
|
|
germline cell cycle switching mitotic to meiotic cell cycle
|
GO:0051729 |
1 |
0.147
|
Worm |
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
18 |
0.146
|
Mouse |
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.145
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.145
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.144
|
Mouse |
|
|
pallium development
|
GO:0021543 |
120 |
0.144
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.141
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.140
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.139
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.139
|
Mouse |
|
|
gland development
|
GO:0048732 |
330 |
0.139
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.136
|
|
|
|
palate development
|
GO:0060021 |
76 |
0.136
|
Zebrafish Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.136
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.135
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.135
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.134
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.132
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.132
|
Mouse |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.132
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.131
|
Mouse |
|
|
insulin secretion
|
GO:0030073 |
89 |
0.127
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.127
|
Worm Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.125
|
Mouse |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.124
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.124
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.124
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.124
|
Mouse |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.123
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.122
|
Mouse |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.122
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.122
|
Mouse |
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.121
|
Worm Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.121
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.120
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.120
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.119
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.118
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.116
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.115
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.115
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.114
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.112
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.112
|
|
|
|
artery development
|
GO:0060840 |
53 |
0.111
|
Mouse |
|
|
b cell activation
|
GO:0042113 |
161 |
0.111
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.111
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.109
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.109
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.109
|
|
|
|
histone methylation
|
GO:0016571 |
71 |
0.108
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.108
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.107
|
Mouse |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.106
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.106
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.105
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.104
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.103
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
35 |
0.102
|
Mouse |
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.102
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.101
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.101
|
Mouse |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.101
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.099
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.098
|
|
|
|
ventricular septum development
|
GO:0003281 |
42 |
0.098
|
Mouse |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.097
|
Fly |
|
|
heart contraction
|
GO:0060047 |
93 |
0.096
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.095
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.095
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.094
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.094
|
Mouse |
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.093
|
Zebrafish |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.093
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.092
|
Mouse |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.092
|
Mouse |
|
|
placenta development
|
GO:0001890 |
140 |
0.092
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.090
|
Mouse |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.090
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.089
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.089
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.088
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.088
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.088
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.087
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
4 |
0.087
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.087
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.087
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.086
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.086
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.086
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.085
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.083
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.083
|
Fly |
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.083
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.083
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
47 |
0.082
|
Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.081
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.081
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.080
|
|
|
|
cerebellum vasculature morphogenesis
|
GO:0061301 |
1 |
0.080
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.079
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.079
|
Fly |
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.079
|
Mouse |
|
|
hindbrain development
|
GO:0030902 |
128 |
0.079
|
Mouse |
|
|
peptide secretion
|
GO:0002790 |
114 |
0.078
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.078
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.077
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.077
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.077
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.077
|
|
|
|
neural crest cell development
|
GO:0014032 |
48 |
0.077
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.077
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.077
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.076
|
Mouse |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.075
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.075
|
Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.075
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.075
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.075
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.074
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.073
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.073
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.073
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.072
|
Mouse |
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.072
|
|
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.072
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.072
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.072
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.071
|
Mouse |
|
|
hormone secretion
|
GO:0046879 |
128 |
0.071
|
Mouse |
|
|
regulation of b cell tolerance induction
|
GO:0002661 |
2 |
0.071
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.071
|
Fly |
|
|
synapse assembly
|
GO:0007416 |
56 |
0.071
|
Fly |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.071
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.070
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.070
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.070
|
|
|
|
positive regulation of cell proliferation involved in heart valve morphogenesis
|
GO:0003251 |
1 |
0.069
|
Mouse |
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.069
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.069
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.068
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.068
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.068
|
Mouse |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.068
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.068
|
Fly |
|
|
progesterone secretion
|
GO:0042701 |
1 |
0.068
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.067
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.067
|
Fly |
|
|
embryonic digit morphogenesis
|
GO:0042733 |
56 |
0.067
|
|
|
|
endoderm development
|
GO:0007492 |
45 |
0.067
|
Mouse Fly |
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.067
|
Mouse |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.067
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.066
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.066
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.066
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.066
|
Zebrafish Fly |
|
|
muscle system process
|
GO:0003012 |
141 |
0.066
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.066
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.065
|
Mouse |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.065
|
Mouse |
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
21 |
0.064
|
Mouse |
|
|
forebrain development
|
GO:0030900 |
302 |
0.064
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.064
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.064
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.063
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.063
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.063
|
Mouse |
|
|
cardiac muscle tissue morphogenesis
|
GO:0055008 |
44 |
0.062
|
Mouse |
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.062
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.062
|
Fly |
|
|
cochlea morphogenesis
|
GO:0090103 |
22 |
0.062
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.062
|
Mouse |
|
|
response to peptide
|
GO:1901652 |
136 |
0.062
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
46 |
0.062
|
Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.061
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.061
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.060
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.060
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.059
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.059
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.059
|
Zebrafish Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.059
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.059
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.059
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.058
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.058
|
Mouse |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.058
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.057
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.057
|
Mouse |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.057
|
Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.057
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.057
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.057
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.057
|
|
|
|
mesoderm formation
|
GO:0001707 |
62 |
0.056
|
Mouse |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.056
|
|
|
|
endothelial cell activation
|
GO:0042118 |
1 |
0.056
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.055
|
|
|
|
somite development
|
GO:0061053 |
81 |
0.055
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.055
|
Mouse |
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.055
|
|
|
|
paraxial mesoderm morphogenesis
|
GO:0048340 |
10 |
0.054
|
Mouse |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.054
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.054
|
|
|
|
neural crest cell migration
|
GO:0001755 |
32 |
0.053
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.053
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.053
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.053
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.053
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.053
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.053
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.053
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.053
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.053
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.052
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.052
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.052
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.052
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.052
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.052
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.052
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.051
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.051
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.051
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.051
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.050
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.050
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.050
|
Mouse |
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
34 |
0.050
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.050
|
Fly |
|
|
branchiomotor neuron axon guidance
|
GO:0021785 |
7 |
0.050
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.050
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.049
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.049
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.049
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.049
|
Mouse |
|
|
regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045898 |
2 |
0.049
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.049
|
Worm Fly |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.048
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.048
|
|
|
|
embryonic axis specification
|
GO:0000578 |
30 |
0.048
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.048
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.048
|
Mouse |
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.048
|
Mouse |
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.048
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.048
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.048
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.047
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.047
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
22 |
0.047
|
Mouse |
|
|
labyrinthine layer blood vessel development
|
GO:0060716 |
21 |
0.047
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.047
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.046
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.046
|
Mouse |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.046
|
Mouse |
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.046
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.046
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.045
|
|
|
|
negative regulation of endothelial cell differentiation
|
GO:0045602 |
2 |
0.045
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.045
|
Fly |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.045
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.045
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.044
|
Fly |
|
|
histone modification
|
GO:0016570 |
159 |
0.044
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.044
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.044
|
|
|
|
lateral mesodermal cell differentiation
|
GO:0048371 |
3 |
0.044
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.043
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.043
|
Mouse |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.043
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.043
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.043
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.043
|
|
|
|
cell differentiation involved in embryonic placenta development
|
GO:0060706 |
26 |
0.043
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.043
|
|
|
|
negative regulation of osteoblast proliferation
|
GO:0033689 |
4 |
0.042
|
Mouse |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.042
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.042
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.042
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.042
|
Mouse |
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
8 |
0.042
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.042
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.042
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.042
|
Fly |
|
|
kidney development
|
GO:0001822 |
213 |
0.042
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.042
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.042
|
|
|
|
lens fiber cell apoptotic process
|
GO:1990086 |
4 |
0.042
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
24 |
0.042
|
|
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.042
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.041
|
Mouse |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.041
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.041
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.041
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.041
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.040
|
Zebrafish Mouse |
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.040
|
Mouse |
|
|
regulation of stem cell differentiation
|
GO:2000736 |
50 |
0.040
|
Mouse |
|
|
pharyngeal system development
|
GO:0060037 |
17 |
0.040
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.040
|
|
|
|
pancreas development
|
GO:0031016 |
57 |
0.040
|
Mouse |
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.040
|
Mouse |
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.040
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.040
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.039
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.039
|
|
|
|
stem cell division
|
GO:0017145 |
30 |
0.039
|
Fly |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.039
|
Worm Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.039
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.039
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.039
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
17 |
0.038
|
|
|
|
paraxial mesoderm development
|
GO:0048339 |
18 |
0.038
|
Mouse |
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.038
|
Zebrafish |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.038
|
Mouse |
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.038
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.038
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.038
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.038
|
|
|
|
lateral mesoderm morphogenesis
|
GO:0048369 |
3 |
0.038
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.038
|
Mouse |
|
|
regulation of axon extension
|
GO:0030516 |
43 |
0.038
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.037
|
|
|
|
regulation of necrotic cell death
|
GO:0010939 |
13 |
0.037
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.037
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.037
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
24 |
0.037
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
51 |
0.037
|
Zebrafish Mouse |
|
|
spermatid development
|
GO:0007286 |
108 |
0.037
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.037
|
Mouse |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.037
|
Mouse |
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
2 |
0.037
|
Mouse |
|
|
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
|
GO:0060715 |
2 |
0.037
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.036
|
Mouse |
|
|
syncytium formation
|
GO:0006949 |
43 |
0.036
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.035
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.035
|
Mouse |
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.035
|
Worm |
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.035
|
Mouse |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.035
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.035
|
Mouse |
|
|
endoderm formation
|
GO:0001706 |
20 |
0.035
|
Mouse Fly |
|
|
defecation
|
GO:0030421 |
1 |
0.035
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.035
|
|
|
|
septum primum development
|
GO:0003284 |
4 |
0.035
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.035
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.035
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.035
|
|
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
2 |
0.035
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.035
|
|
|
|
germinal center formation
|
GO:0002467 |
16 |
0.035
|
|
|
|
cerebellum vasculature development
|
GO:0061300 |
1 |
0.035
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.035
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
59 |
0.034
|
|
|
|
cell cycle switching mitotic to meiotic cell cycle
|
GO:0051728 |
1 |
0.034
|
Worm |
|
|
cell growth
|
GO:0016049 |
130 |
0.034
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.034
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.034
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
36 |
0.034
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
12 |
0.034
|
Fly |
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
35 |
0.034
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
65 |
0.033
|
Zebrafish Mouse |
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.033
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.033
|
Mouse |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.033
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.033
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.033
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.033
|
Worm Fly |
|
|
female gonad development
|
GO:0008585 |
71 |
0.033
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
31 |
0.033
|
Mouse |
|
|
regulation of cell fate commitment
|
GO:0010453 |
19 |
0.033
|
|
|
|
negative regulation of hormone metabolic process
|
GO:0032351 |
4 |
0.033
|
|
|
|
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045899 |
2 |
0.033
|
|
|
|
heterochromatin organization
|
GO:0070828 |
4 |
0.033
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.033
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.033
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.033
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.032
|
|
