Mus musculus

15 known processes

Sytl1

synaptotagmin-like 1

(Aliases: Slp1,PSGL-1,9030417L18,MGC7008)

Sytl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein maturation GO:0051604 176 0.140
small gtpase mediated signal transduction GO:0007264 97 0.102
amine metabolic process GO:0009308 45 0.099
nucleobase containing small molecule metabolic process GO:0055086 352 0.074
macromolecule catabolic process GO:0009057 281 0.070
inflammatory response GO:0006954 244 0.069
regulation of cellular ketone metabolic process GO:0010565 66 0.068
cellular lipid metabolic process GO:0044255 323 0.067
ras protein signal transduction GO:0007265 77 0.066
cellular nitrogen compound catabolic process GO:0044270 280 0.066
nucleoside phosphate metabolic process GO:0006753 338 0.063
purine containing compound metabolic process GO:0072521 311 0.062
guanosine containing compound metabolic process GO:1901068 144 0.062
striated muscle contraction GO:0006941 45 0.061
response to radiation GO:0009314 165 0.060
regulation of secretion by cell GO:1903530 249 0.058
Mouse
ion transmembrane transport GO:0034220 361 0.058
regulation of cellular amino acid metabolic process GO:0006521 5 0.058
carbohydrate derivative catabolic process GO:1901136 231 0.056
aromatic compound catabolic process GO:0019439 286 0.055
transmembrane transport GO:0055085 412 0.055
muscle system process GO:0003012 141 0.053
rho protein signal transduction GO:0007266 32 0.052
protein processing GO:0016485 163 0.051
purine nucleotide metabolic process GO:0006163 302 0.051
cellular response to lipid GO:0071396 145 0.049
nucleotide metabolic process GO:0009117 332 0.048
cellular amine metabolic process GO:0044106 44 0.048
sensory perception GO:0007600 245 0.047
regulation of protein kinase activity GO:0045859 232 0.047
response to organonitrogen compound GO:0010243 246 0.047
metal ion homeostasis GO:0055065 189 0.047
glycosyl compound metabolic process GO:1901657 246 0.047
organonitrogen compound catabolic process GO:1901565 264 0.046
cellular ketone metabolic process GO:0042180 84 0.046
cellular amino acid metabolic process GO:0006520 103 0.044
protein catabolic process GO:0030163 221 0.044
ribose phosphate metabolic process GO:0019693 291 0.044
muscle tissue development GO:0060537 308 0.044
synaptic transmission GO:0007268 329 0.043
nucleoside triphosphate catabolic process GO:0009143 205 0.043
negative regulation of cellular component organization GO:0051129 194 0.043
cardiac muscle contraction GO:0060048 32 0.042
purine ribonucleoside metabolic process GO:0046128 241 0.042
muscle contraction GO:0006936 101 0.042
actin cytoskeleton organization GO:0030036 220 0.041
Fly
inorganic ion transmembrane transport GO:0098660 234 0.041
regulation of protein transport GO:0051223 163 0.041
t cell activation GO:0042110 289 0.041
regulation of transferase activity GO:0051338 263 0.041
skeletal system development GO:0001501 356 0.040
regulation of anatomical structure size GO:0090066 178 0.040
Fly
regulation of response to wounding GO:1903034 189 0.039
regulation of establishment of protein localization GO:0070201 181 0.039
ribonucleoside metabolic process GO:0009119 245 0.039
cellular homeostasis GO:0019725 240 0.039
endomembrane system organization GO:0010256 147 0.038
microtubule based process GO:0007017 236 0.038
purine ribonucleoside catabolic process GO:0046130 205 0.038
organic cyclic compound catabolic process GO:1901361 295 0.038
g protein coupled receptor signaling pathway GO:0007186 243 0.037
regulation of kinase activity GO:0043549 249 0.037
organophosphate catabolic process GO:0046434 232 0.037
detection of stimulus GO:0051606 84 0.037
multicellular organismal homeostasis GO:0048871 164 0.037
ribonucleoside triphosphate catabolic process GO:0009203 199 0.036
peptidyl amino acid modification GO:0018193 336 0.036
regulation of cellular component biogenesis GO:0044087 181 0.036
reactive oxygen species metabolic process GO:0072593 84 0.036
nucleotide catabolic process GO:0009166 217 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
blood circulation GO:0008015 195 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.035
regulation of organelle organization GO:0033043 289 0.035
endocytosis GO:0006897 168 0.034
positive regulation of protein modification process GO:0031401 299 0.034
regulation of protein localization GO:0032880 231 0.034
nucleoside phosphate catabolic process GO:1901292 222 0.034
cellular macromolecule catabolic process GO:0044265 206 0.033
protein localization to membrane GO:0072657 108 0.033
fatty acid metabolic process GO:0006631 121 0.033
developmental maturation GO:0021700 193 0.032
ribonucleoside catabolic process GO:0042454 206 0.032
striated muscle tissue development GO:0014706 293 0.032
sensory organ morphogenesis GO:0090596 242 0.032
organelle fission GO:0048285 170 0.031
germ cell development GO:0007281 185 0.031
skin development GO:0043588 220 0.030
cell adhesion GO:0007155 329 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.029
regulation of secretion GO:0051046 274 0.029
Mouse
purine containing compound catabolic process GO:0072523 213 0.029
organelle localization GO:0051640 179 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.028
heterocycle catabolic process GO:0046700 280 0.028
response to light stimulus GO:0009416 135 0.028
cellular response to dna damage stimulus GO:0006974 207 0.028
ribonucleotide catabolic process GO:0009261 208 0.028
sensory perception of mechanical stimulus GO:0050954 107 0.028
regulation of cellular catabolic process GO:0031329 242 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
retina development in camera type eye GO:0060041 119 0.027
dna metabolic process GO:0006259 303 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
purine nucleoside triphosphate catabolic process GO:0009146 203 0.027
transmission of nerve impulse GO:0019226 76 0.027
glycosyl compound catabolic process GO:1901658 206 0.027
gtp metabolic process GO:0046039 144 0.026
homeostasis of number of cells GO:0048872 210 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
sensory perception of sound GO:0007605 97 0.026
regulation of ion transport GO:0043269 215 0.026
lymphocyte activation involved in immune response GO:0002285 93 0.026
purine ribonucleotide catabolic process GO:0009154 208 0.026
dephosphorylation GO:0016311 129 0.026
membrane organization GO:0061024 245 0.025
heart process GO:0003015 94 0.025
nucleoside catabolic process GO:0009164 206 0.025
detection of external stimulus GO:0009581 61 0.025
gtp catabolic process GO:0006184 143 0.025
carbohydrate homeostasis GO:0033500 128 0.025
gland development GO:0048732 330 0.025
Fly
lymphocyte differentiation GO:0030098 242 0.025
regulation of hydrolase activity GO:0051336 246 0.025
regulation of cytokine production GO:0001817 266 0.025
anatomical structure homeostasis GO:0060249 145 0.025
oxidation reduction process GO:0055114 342 0.025
nucleoside metabolic process GO:0009116 246 0.024
wound healing GO:0042060 157 0.024
regulation of cell activation GO:0050865 289 0.024
glucose homeostasis GO:0042593 128 0.024
regulation of vesicle mediated transport GO:0060627 139 0.024
microtubule cytoskeleton organization GO:0000226 157 0.024
regulation of hormone levels GO:0010817 211 0.024
Mouse
cell activation involved in immune response GO:0002263 126 0.024
leukocyte activation involved in immune response GO:0002366 126 0.024
cofactor transport GO:0051181 4 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
cation transmembrane transport GO:0098655 266 0.023
cellular response to organonitrogen compound GO:0071417 145 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
male gamete generation GO:0048232 285 0.023
amide transport GO:0042886 138 0.023
Mouse
camera type eye development GO:0043010 266 0.023
positive regulation of secretion by cell GO:1903532 114 0.023
regulation of cell cycle GO:0051726 281 0.022
response to molecule of bacterial origin GO:0002237 143 0.022
establishment of organelle localization GO:0051656 122 0.022
positive regulation of kinase activity GO:0033674 155 0.022
cation transport GO:0006812 399 0.022
regulation of neuron differentiation GO:0045664 281 0.022
citrulline biosynthetic process GO:0019240 2 0.022
muscle cell differentiation GO:0042692 261 0.022
cellular protein catabolic process GO:0044257 155 0.022
regulation of system process GO:0044057 200 0.022
negative regulation of molecular function GO:0044092 258 0.022
mapk cascade GO:0000165 281 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
leukocyte differentiation GO:0002521 342 0.022
regulation of membrane potential GO:0042391 192 0.022
compound eye development GO:0048749 1 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.021
protein citrullination GO:0018101 2 0.021
wnt signaling pathway GO:0016055 188 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
mitotic cell cycle GO:0000278 195 0.021
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.021
nuclear division GO:0000280 158 0.021
detection of abiotic stimulus GO:0009582 60 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
sodium ion transport GO:0006814 73 0.021
circulatory system process GO:0003013 197 0.021
cellular response to acid chemical GO:0071229 68 0.021
synapse organization GO:0050808 125 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
modification dependent macromolecule catabolic process GO:0043632 133 0.020
cell type specific apoptotic process GO:0097285 268 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.020
positive regulation of nucleotide metabolic process GO:0045981 114 0.020
positive regulation of hydrolase activity GO:0051345 148 0.020
regulation of inflammatory response GO:0050727 147 0.019
protein secretion GO:0009306 111 0.019
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.019
regulation of body fluid levels GO:0050878 162 0.019
Mouse
inorganic anion transport GO:0015698 43 0.019
multi multicellular organism process GO:0044706 109 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
cytokine production GO:0001816 319 0.019
regulation of defense response GO:0031347 233 0.019
regulation of metal ion transport GO:0010959 106 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
actin filament organization GO:0007015 113 0.019
Fly
regulation of cellular amine metabolic process GO:0033238 20 0.019
asymmetric stem cell division GO:0098722 3 0.018
oocyte axis specification GO:0007309 2 0.018
apoptotic signaling pathway GO:0097190 306 0.018
engulfment of apoptotic cell GO:0043652 3 0.018
cellularization GO:0007349 1 0.018
natural killer cell degranulation GO:0043320 3 0.018
regulation of rho protein signal transduction GO:0035023 71 0.018
myeloid leukocyte differentiation GO:0002573 119 0.018
zymogen activation GO:0031638 41 0.018
nitrogen compound transport GO:0071705 271 0.018
Mouse
calcium ion homeostasis GO:0055074 127 0.018
regulation of leukocyte differentiation GO:1902105 159 0.017
response to acid chemical GO:0001101 111 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
divalent inorganic cation transport GO:0072511 178 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
maternal determination of anterior posterior axis embryo GO:0008358 2 0.017
oocyte construction GO:0007308 2 0.017
spermatogenesis GO:0007283 284 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
regulation of blood pressure GO:0008217 93 0.017
covalent chromatin modification GO:0016569 163 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
regulation of homeostatic process GO:0032844 182 0.017
positive regulation of protein transport GO:0051222 93 0.017
meiotic cell cycle process GO:1903046 77 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
axonogenesis GO:0007409 274 0.017
positive regulation of nervous system development GO:0051962 221 0.017
regulation of blood vessel size GO:0050880 56 0.017
sensory perception of light stimulus GO:0050953 54 0.017
interleukin 8 secretion GO:0072606 3 0.016
oocyte anterior posterior axis specification GO:0007314 2 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
regulation of cell projection organization GO:0031344 206 0.016
regulation of actin filament based process GO:0032970 99 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
cardiac muscle cell contraction GO:0086003 7 0.016
regulation of peptidase activity GO:0052547 96 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
phospholipid metabolic process GO:0006644 87 0.016
t cell differentiation GO:0030217 174 0.016
embryonic limb morphogenesis GO:0030326 126 0.016
germ line stem cell division GO:0042078 2 0.016
fat cell differentiation GO:0045444 160 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
intracellular protein transport GO:0006886 204 0.015
epidermis development GO:0008544 187 0.015
negative regulation of immune system process GO:0002683 209 0.015
heart contraction GO:0060047 93 0.015
peptidyl serine modification GO:0018209 83 0.015
immune effector process GO:0002252 321 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
positive regulation of secretion GO:0051047 130 0.015
Mouse
cellular amide metabolic process GO:0043603 58 0.015
lateral inhibition GO:0046331 1 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
establishment of protein localization to membrane GO:0090150 54 0.015
chromatin organization GO:0006325 206 0.015
cellular protein complex assembly GO:0043623 116 0.015
regulation of cytoskeleton organization GO:0051493 122 0.015
action potential GO:0001508 78 0.015
cell recognition GO:0008037 83 0.015
protein localization to plasma membrane GO:0072659 57 0.015
negative regulation of nervous system development GO:0051961 156 0.015
leukocyte proliferation GO:0070661 172 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
regulation of systemic arterial blood pressure GO:0003073 61 0.015
av node cell to bundle of his cell communication GO:0086067 2 0.015
cell cell junction organization GO:0045216 72 0.015
Fly
ossification GO:0001503 216 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
fertilization GO:0009566 127 0.014
tissue homeostasis GO:0001894 115 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
muscle cell development GO:0055001 133 0.014
regulation of transmembrane transport GO:0034762 128 0.014
negative regulation of response to wounding GO:1903035 77 0.014
histone modification GO:0016570 159 0.014
regulation of cell cycle process GO:0010564 160 0.014
cardiac ventricle development GO:0003231 83 0.014
peptide secretion GO:0002790 114 0.014
Mouse
regulation of t cell activation GO:0050863 170 0.014
carbohydrate metabolic process GO:0005975 230 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
intracellular mrna localization GO:0008298 4 0.014
calcium ion transport GO:0006816 159 0.014
heart morphogenesis GO:0003007 178 0.014
meiotic cell cycle GO:0051321 122 0.014
negative regulation of cell cycle GO:0045786 123 0.014
response to organic cyclic compound GO:0014070 198 0.014
positive regulation of organelle organization GO:0010638 128 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
pigment granule localization GO:0051875 13 0.013
cellular response to abiotic stimulus GO:0071214 56 0.013
exocytosis GO:0006887 121 0.013
regulation of endocytosis GO:0030100 69 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
negative regulation of cell development GO:0010721 169 0.013
regulation of neuron projection development GO:0010975 169 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
dendrite development GO:0016358 115 0.013
proteoglycan metabolic process GO:0006029 38 0.013
organic acid biosynthetic process GO:0016053 86 0.013
regulation of interleukin 8 secretion GO:2000482 2 0.013
regulation of renin secretion into blood stream GO:1900133 4 0.013
hexose metabolic process GO:0019318 98 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
regulation of protein catabolic process GO:0042176 108 0.013
endocrine process GO:0050886 39 0.013
alpha beta t cell activation GO:0046631 91 0.013
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
regulation of protein complex assembly GO:0043254 83 0.013
multicellular organismal signaling GO:0035637 91 0.013
cell cell recognition GO:0009988 44 0.013
cellular response to lipopolysaccharide GO:0071222 77 0.013
neuronal action potential GO:0019228 54 0.013
regulation of t cell anergy GO:0002667 4 0.013
cell maturation GO:0048469 127 0.013
negative regulation of organelle organization GO:0010639 90 0.013
sphingolipid metabolic process GO:0006665 45 0.013
macromolecule methylation GO:0043414 120 0.013
regulation of protein secretion GO:0050708 82 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
regulation of interleukin 8 production GO:0032677 3 0.012
regulation of lymphocyte anergy GO:0002911 4 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
regulation of engulfment of apoptotic cell GO:1901074 2 0.012
coagulation GO:0050817 78 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
pole plasm assembly GO:0007315 2 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
lipid biosynthetic process GO:0008610 179 0.012
response to lipopolysaccharide GO:0032496 128 0.012
ear morphogenesis GO:0042471 118 0.012
cellular chemical homeostasis GO:0055082 215 0.012
sulfur compound metabolic process GO:0006790 100 0.012
striated muscle cell development GO:0055002 125 0.012
regulation of actin cytoskeleton organization GO:0032956 84 0.012
positive regulation of cell death GO:0010942 224 0.012
anion transport GO:0006820 177 0.012
interleukin 8 production GO:0032637 4 0.012
hypotonic response GO:0006971 3 0.012
ear development GO:0043583 200 0.012
signal transduction involved in cell cycle checkpoint GO:0072395 3 0.012
positive regulation of cell development GO:0010720 237 0.012
hair follicle development GO:0001942 85 0.012
membrane lipid metabolic process GO:0006643 53 0.012
cellular ion homeostasis GO:0006873 165 0.012
regulation of cellular component size GO:0032535 121 0.012
Fly
ameboidal type cell migration GO:0001667 128 0.012
cellular response to biotic stimulus GO:0071216 92 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
vesicle localization GO:0051648 86 0.012
locomotory behavior GO:0007626 195 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
mrna metabolic process GO:0016071 84 0.011
chromosome segregation GO:0007059 48 0.011
positive regulation of proteolysis GO:0045862 85 0.011
cd4 positive alpha beta t cell activation GO:0035710 45 0.011
single fertilization GO:0007338 82 0.011
peptide hormone secretion GO:0030072 109 0.011
Mouse
biomineral tissue development GO:0031214 64 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
meiotic nuclear division GO:0007126 115 0.011
epithelial cell development GO:0002064 159 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
vasodilation GO:0042311 28 0.011
organelle assembly GO:0070925 177 0.011
alpha amino acid biosynthetic process GO:1901607 15 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
extracellular structure organization GO:0043062 148 0.011
protein localization to organelle GO:0033365 185 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
mitotic cytokinesis GO:0000281 4 0.011
t cell activation involved in immune response GO:0002286 43 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
detection of visible light GO:0009584 14 0.011
regulation of mapk cascade GO:0043408 248 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
regulation of cellular response to stress GO:0080135 159 0.011
cell division GO:0051301 120 0.011
cardiac chamber morphogenesis GO:0003206 93 0.011
protein ubiquitination GO:0016567 171 0.011
insulin secretion GO:0030073 89 0.011
Mouse
establishment of vesicle localization GO:0051650 81 0.011
ceramide metabolic process GO:0006672 31 0.011
appendage morphogenesis GO:0035107 149 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
ceramide biosynthetic process GO:0046513 20 0.011
regulation of leukocyte apoptotic process GO:2000106 56 0.011
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.011
maintenance of location GO:0051235 89 0.010
peptide metabolic process GO:0006518 46 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
chromatin modification GO:0016568 187 0.010
limb morphogenesis GO:0035108 149 0.010
appendage development GO:0048736 166 0.010
alpha beta t cell differentiation GO:0046632 69 0.010
rab protein signal transduction GO:0032482 1 0.010
membrane depolarization GO:0051899 64 0.010
positive regulation of protein secretion GO:0050714 52 0.010
monosaccharide metabolic process GO:0005996 106 0.010
cell cycle switching GO:0060184 1 0.010
establishment of protein localization to plasma membrane GO:0090002 34 0.010
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010
cellular alcohol metabolic process GO:0044107 3 0.010
response to testosterone GO:0033574 3 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
glycoprotein metabolic process GO:0009100 116 0.010

Sytl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.024
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.015
sensory system disease DOID:0050155 0 0.015
disease of cellular proliferation DOID:14566 0 0.014
eye disease DOID:5614 0 0.013
retinitis pigmentosa DOID:10584 0 0.013
eye and adnexa disease DOID:1492 0 0.013
retinal degeneration DOID:8466 0 0.013
retinal disease DOID:5679 0 0.013
connective tissue disease DOID:65 0 0.012
bone disease DOID:0080001 0 0.012