Mus musculus

0 known processes

Lrfn3

leucine rich repeat and fibronectin type III domain containing 3

(Aliases: SALM4,A530045B06Rik)

Lrfn3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.111
nucleoside phosphate metabolic process GO:0006753 338 0.098
cellular amine metabolic process GO:0044106 44 0.085
amine metabolic process GO:0009308 45 0.084
regulation of cellular ketone metabolic process GO:0010565 66 0.083
nucleotide metabolic process GO:0009117 332 0.082
regulation of cellular amine metabolic process GO:0033238 20 0.078
regulation of cellular amino acid metabolic process GO:0006521 5 0.078
cellular ketone metabolic process GO:0042180 84 0.076
regulation of cell projection organization GO:0031344 206 0.075
purine ribonucleotide metabolic process GO:0009150 290 0.070
regulation of organelle organization GO:0033043 289 0.065
nucleoside metabolic process GO:0009116 246 0.064
positive regulation of cellular catabolic process GO:0031331 148 0.062
purine nucleoside triphosphate metabolic process GO:0009144 226 0.062
ribose phosphate metabolic process GO:0019693 291 0.061
regulation of kinase activity GO:0043549 249 0.061
cellular amino acid metabolic process GO:0006520 103 0.060
small gtpase mediated signal transduction GO:0007264 97 0.059
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.058
microtubule based process GO:0007017 236 0.058
nucleoside phosphate catabolic process GO:1901292 222 0.057
purine nucleoside metabolic process GO:0042278 241 0.056
positive regulation of cellular amine metabolic process GO:0033240 5 0.054
regulation of cellular catabolic process GO:0031329 242 0.054
purine nucleotide metabolic process GO:0006163 302 0.053
purine ribonucleotide catabolic process GO:0009154 208 0.053
ribonucleotide metabolic process GO:0009259 291 0.051
purine nucleoside catabolic process GO:0006152 205 0.051
aromatic compound catabolic process GO:0019439 286 0.050
guanosine containing compound catabolic process GO:1901069 144 0.050
heterocycle catabolic process GO:0046700 280 0.050
nucleobase containing small molecule metabolic process GO:0055086 352 0.050
glycosyl compound catabolic process GO:1901658 206 0.049
regulation of nucleotide metabolic process GO:0006140 169 0.049
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.049
protein catabolic process GO:0030163 221 0.049
macromolecule catabolic process GO:0009057 281 0.048
regulation of secretion GO:0051046 274 0.048
purine containing compound metabolic process GO:0072521 311 0.048
mapk cascade GO:0000165 281 0.048
organic cyclic compound catabolic process GO:1901361 295 0.046
regulation of membrane potential GO:0042391 192 0.046
regulation of cytoskeleton organization GO:0051493 122 0.046
negative regulation of molecular function GO:0044092 258 0.045
purine ribonucleoside metabolic process GO:0046128 241 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.045
regulation of transferase activity GO:0051338 263 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.044
regulation of purine nucleotide metabolic process GO:1900542 169 0.044
regulation of ras gtpase activity GO:0032318 88 0.044
regulation of nucleoside metabolic process GO:0009118 130 0.044
guanosine containing compound metabolic process GO:1901068 144 0.044
microtubule cytoskeleton organization GO:0000226 157 0.044
ribonucleoside metabolic process GO:0009119 245 0.044
cellular nitrogen compound catabolic process GO:0044270 280 0.043
regulation of cellular response to stress GO:0080135 159 0.042
rho protein signal transduction GO:0007266 32 0.042
nucleoside triphosphate catabolic process GO:0009143 205 0.042
transmission of nerve impulse GO:0019226 76 0.041
carbohydrate derivative catabolic process GO:1901136 231 0.041
protein modification by small protein conjugation GO:0032446 187 0.040
glycosyl compound metabolic process GO:1901657 246 0.039
negative regulation of cellular component organization GO:0051129 194 0.038
actin cytoskeleton organization GO:0030036 220 0.038
purine ribonucleoside catabolic process GO:0046130 205 0.038
organophosphate catabolic process GO:0046434 232 0.038
ribonucleoside triphosphate metabolic process GO:0009199 220 0.038
regulation of neuron projection development GO:0010975 169 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.037
nucleoside catabolic process GO:0009164 206 0.036
ribonucleoside triphosphate catabolic process GO:0009203 199 0.036
membrane organization GO:0061024 245 0.036
purine containing compound catabolic process GO:0072523 213 0.036
regulation of gtp catabolic process GO:0033124 113 0.035
intracellular protein transport GO:0006886 204 0.035
purine nucleotide catabolic process GO:0006195 211 0.035
regulation of protein kinase activity GO:0045859 232 0.035
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
regulation of hydrolase activity GO:0051336 246 0.032
wnt signaling pathway GO:0016055 188 0.032
epithelial tube morphogenesis GO:0060562 303 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
ribonucleoside catabolic process GO:0042454 206 0.032
peptidyl amino acid modification GO:0018193 336 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
gtp metabolic process GO:0046039 144 0.031
regulation of mapk cascade GO:0043408 248 0.030
positive regulation of gtp catabolic process GO:0033126 85 0.030
positive regulation of hydrolase activity GO:0051345 148 0.030
multicellular organismal signaling GO:0035637 91 0.030
positive regulation of protein phosphorylation GO:0001934 242 0.029
gtp catabolic process GO:0006184 143 0.029
synaptic transmission GO:0007268 329 0.029
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.029
circulatory system process GO:0003013 197 0.028
organelle localization GO:0051640 179 0.028
regulation of cellular component biogenesis GO:0044087 181 0.028
regulation of nucleotide catabolic process GO:0030811 122 0.028
peptidyl tyrosine phosphorylation GO:0018108 143 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
regulation of cellular response to growth factor stimulus GO:0090287 82 0.028
positive regulation of nervous system development GO:0051962 221 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.027
regulation of body fluid levels GO:0050878 162 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
regulation of anatomical structure size GO:0090066 178 0.027
ossification GO:0001503 216 0.027
wound healing GO:0042060 157 0.026
positive regulation of kinase activity GO:0033674 155 0.026
peptidyl tyrosine modification GO:0018212 145 0.026
carbohydrate metabolic process GO:0005975 230 0.026
positive regulation of cell development GO:0010720 237 0.026
neuronal action potential GO:0019228 54 0.026
positive regulation of gtpase activity GO:0043547 85 0.025
protein ubiquitination GO:0016567 171 0.025
transmembrane transport GO:0055085 412 0.025
compound eye development GO:0048749 1 0.025
apoptotic signaling pathway GO:0097190 306 0.024
positive regulation of cell projection organization GO:0031346 95 0.024
tube formation GO:0035148 140 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
positive regulation of ras gtpase activity GO:0032320 65 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
spermatogenesis GO:0007283 284 0.024
dendrite development GO:0016358 115 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
ubiquitin dependent protein catabolic process GO:0006511 129 0.024
chemotaxis GO:0006935 247 0.023
response to organonitrogen compound GO:0010243 246 0.023
regulation of purine nucleotide catabolic process GO:0033121 122 0.023
camera type eye development GO:0043010 266 0.023
gland development GO:0048732 330 0.022
lipid biosynthetic process GO:0008610 179 0.022
positive regulation of nucleotide catabolic process GO:0030813 88 0.022
male gamete generation GO:0048232 285 0.022
regulation of neuron differentiation GO:0045664 281 0.022
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
regulation of secretion by cell GO:1903530 249 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
negative regulation of cell projection organization GO:0031345 56 0.021
neural tube formation GO:0001841 108 0.021
positive regulation of mapk cascade GO:0043410 170 0.021
regulation of actin cytoskeleton organization GO:0032956 84 0.021
regulation of cellular component size GO:0032535 121 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
oxidation reduction process GO:0055114 342 0.021
mitotic cell cycle GO:0000278 195 0.021
cellular response to organonitrogen compound GO:0071417 145 0.020
synapse organization GO:0050808 125 0.020
forebrain development GO:0030900 302 0.020
negative regulation of growth GO:0045926 99 0.020
regulation of establishment of planar polarity GO:0090175 28 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
regulation of ras protein signal transduction GO:0046578 114 0.020
locomotory behavior GO:0007626 195 0.020
neural tube development GO:0021915 160 0.020
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.020
action potential GO:0001508 78 0.020
regulation of cell cycle GO:0051726 281 0.020
cellular protein catabolic process GO:0044257 155 0.020
positive regulation of neuron projection development GO:0010976 79 0.020
regulation of cell activation GO:0050865 289 0.019
cognition GO:0050890 149 0.019
blood circulation GO:0008015 195 0.019
regulation of cell size GO:0008361 72 0.019
positive regulation of neuron differentiation GO:0045666 141 0.019
lymphocyte differentiation GO:0030098 242 0.019
metal ion homeostasis GO:0055065 189 0.018
regulation of protein catabolic process GO:0042176 108 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
nucleotide catabolic process GO:0009166 217 0.018
regulation of protein localization GO:0032880 231 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
sensory perception GO:0007600 245 0.018
establishment of tissue polarity GO:0007164 28 0.018
regulation of wnt signaling pathway GO:0030111 123 0.018
protein targeting GO:0006605 143 0.018
establishment of organelle localization GO:0051656 122 0.018
regulation of map kinase activity GO:0043405 120 0.018
embryonic epithelial tube formation GO:0001838 130 0.017
regulation of postsynaptic membrane potential GO:0060078 48 0.017
cell fate commitment GO:0045165 210 0.017
canonical wnt signaling pathway GO:0060070 130 0.017
negative regulation of protein modification process GO:0031400 163 0.017
regulation of rho gtpase activity GO:0032319 58 0.017
digestive tract morphogenesis GO:0048546 147 0.017
single organism cell adhesion GO:0098602 156 0.017
epithelial tube formation GO:0072175 130 0.017
jnk cascade GO:0007254 72 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.017
positive regulation of protein modification process GO:0031401 299 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
leukocyte differentiation GO:0002521 342 0.017
gonad development GO:0008406 141 0.017
germ cell development GO:0007281 185 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.017
positive regulation of organelle organization GO:0010638 128 0.017
protein localization to organelle GO:0033365 185 0.017
lateral inhibition GO:0046331 1 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
digestive system development GO:0055123 200 0.017
organelle assembly GO:0070925 177 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
cell adhesion GO:0007155 329 0.016
endomembrane system organization GO:0010256 147 0.016
axonogenesis GO:0007409 274 0.016
sulfur compound metabolic process GO:0006790 100 0.016
negative regulation of synapse assembly GO:0051964 3 0.016
stress activated mapk cascade GO:0051403 80 0.016
cellular homeostasis GO:0019725 240 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
cell type specific apoptotic process GO:0097285 268 0.016
response to growth factor GO:0070848 198 0.016
positive regulation of transferase activity GO:0051347 167 0.016
establishment of vesicle localization GO:0051650 81 0.015
sulfur compound biosynthetic process GO:0044272 37 0.015
nuclear division GO:0000280 158 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
regulation of cell growth GO:0001558 91 0.015
rap protein signal transduction GO:0032486 3 0.015
muscle cell differentiation GO:0042692 261 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
regulation of interleukin 8 production GO:0032677 3 0.015
regulation of canonical wnt signaling pathway GO:0060828 82 0.015
protein localization to membrane GO:0072657 108 0.015
cell recognition GO:0008037 83 0.015
respiratory tube development GO:0030323 167 0.015
synaptic transmission glutamatergic GO:0035249 36 0.015
organelle fission GO:0048285 170 0.015
regulation of system process GO:0044057 200 0.015
t cell activation GO:0042110 289 0.015
telencephalon development GO:0021537 186 0.014
cell division GO:0051301 120 0.014
peptidyl serine phosphorylation GO:0018105 74 0.014
immune effector process GO:0002252 321 0.014
regulation of axon extension GO:0030516 43 0.014
developmental cell growth GO:0048588 84 0.014
neurotransmitter secretion GO:0007269 62 0.014
regulation of extent of cell growth GO:0061387 52 0.014
sensory system development GO:0048880 3 0.014
positive regulation of secretion GO:0051047 130 0.014
regulation of hormone levels GO:0010817 211 0.014
response to peptide hormone GO:0043434 127 0.014
neuron projection guidance GO:0097485 141 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
tube closure GO:0060606 91 0.014
cellular response to peptide hormone stimulus GO:0071375 92 0.014
stress activated protein kinase signaling cascade GO:0031098 81 0.014
ameboidal type cell migration GO:0001667 128 0.014
male sex differentiation GO:0046661 109 0.014
primary neural tube formation GO:0014020 95 0.014
ensheathment of neurons GO:0007272 76 0.014
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.014
development of primary sexual characteristics GO:0045137 143 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
regulation of jnk cascade GO:0046328 62 0.013
regulation of feeding behavior GO:0060259 3 0.013
regulation of proteolysis GO:0030162 164 0.013
protein maturation GO:0051604 176 0.013
glycoprotein metabolic process GO:0009100 116 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
sensory organ morphogenesis GO:0090596 242 0.013
skeletal system development GO:0001501 356 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
cytoplasmic transport GO:0016482 234 0.013
glial cell differentiation GO:0010001 131 0.013
angiogenesis GO:0001525 201 0.013
nuclear transport GO:0051169 139 0.013
positive regulation of cell activation GO:0050867 158 0.013
negative regulation of cell development GO:0010721 169 0.013
cellular response to peptide GO:1901653 92 0.013
protein processing GO:0016485 163 0.013
maintenance of location GO:0051235 89 0.013
neurotransmitter transport GO:0006836 76 0.013
synaptic vesicle transport GO:0048489 57 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
small molecule biosynthetic process GO:0044283 132 0.013
homeostasis of number of cells GO:0048872 210 0.013
cellular lipid metabolic process GO:0044255 323 0.013
synaptic vesicle localization GO:0097479 59 0.012
regulation of heart contraction GO:0008016 77 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
asymmetric stem cell division GO:0098722 3 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
negative regulation of nervous system development GO:0051961 156 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
regulation of stress activated mapk cascade GO:0032872 69 0.012
myeloid cell differentiation GO:0030099 233 0.012
monosaccharide metabolic process GO:0005996 106 0.012
neuromuscular process GO:0050905 99 0.012
lipid localization GO:0010876 126 0.012
response to radiation GO:0009314 165 0.012
defecation GO:0030421 1 0.012
retina development in camera type eye GO:0060041 119 0.012
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.012
establishment of planar polarity GO:0001736 28 0.012
positive regulation of leukocyte differentiation GO:1902107 86 0.012
lateral line system development GO:0048925 1 0.012
interleukin 8 production GO:0032637 4 0.012
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
pharynx development GO:0060465 1 0.012
response to peptide GO:1901652 136 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
neuron projection extension GO:1990138 64 0.012
regulation of cell cycle process GO:0010564 160 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
developmental maturation GO:0021700 193 0.012
cell maturation GO:0048469 127 0.011
blood vessel morphogenesis GO:0048514 285 0.011
regulation of cell migration GO:0030334 219 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
response to insulin GO:0032868 100 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
glucose homeostasis GO:0042593 128 0.011
cytokine production GO:0001816 319 0.011
peptide transport GO:0015833 133 0.011
regulation of protein complex assembly GO:0043254 83 0.011
negative regulation of wnt signaling pathway GO:0030178 73 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
protein secretion GO:0009306 111 0.011
metencephalon development GO:0022037 89 0.011
regulation of vasculature development GO:1901342 88 0.011
chromatin organization GO:0006325 206 0.011
regulation of receptor activity GO:0010469 41 0.011
anatomical structure homeostasis GO:0060249 145 0.011
epithelial cell development GO:0002064 159 0.011
skeletal system morphogenesis GO:0048705 203 0.011
positive regulation of rho gtpase activity GO:0032321 41 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
hexose metabolic process GO:0019318 98 0.011
negative regulation of neuron differentiation GO:0045665 101 0.011
positive regulation of proteolysis GO:0045862 85 0.011
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.011
midgut development GO:0007494 4 0.011
response to inorganic substance GO:0010035 96 0.011
asymmetric neuroblast division GO:0055059 1 0.011
epithelial cell proliferation GO:0050673 174 0.011
response to light stimulus GO:0009416 135 0.011
non canonical wnt signaling pathway GO:0035567 33 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
negative regulation of neuron projection development GO:0010977 50 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
ion transmembrane transport GO:0034220 361 0.011
plasma membrane organization GO:0007009 90 0.011
positive regulation of protein complex assembly GO:0031334 45 0.011
regulation of neuron death GO:1901214 134 0.011
protein localization to nucleus GO:0034504 121 0.011
appendage development GO:0048736 166 0.011
response to acid chemical GO:0001101 111 0.011
digestive tract development GO:0048565 190 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.011
regulation of binding GO:0051098 111 0.011
neuron neuron synaptic transmission GO:0007270 69 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
alcohol metabolic process GO:0006066 116 0.011
learning or memory GO:0007611 148 0.011
neural precursor cell proliferation GO:0061351 121 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
dna metabolic process GO:0006259 303 0.011
axon guidance GO:0007411 141 0.011
cell junction organization GO:0034330 77 0.011
generation of precursor metabolites and energy GO:0006091 103 0.010
peptidyl serine modification GO:0018209 83 0.010
neural tube closure GO:0001843 90 0.010
regulation of actin filament based process GO:0032970 99 0.010
negative regulation of cell growth GO:0030308 44 0.010
dephosphorylation GO:0016311 129 0.010
notochord cell development GO:0060035 1 0.010
regulation of neurotransmitter levels GO:0001505 87 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
cellular chemical homeostasis GO:0055082 215 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
regulation of ovulation GO:0060278 3 0.010
protein import into nucleus GO:0006606 95 0.010
hormone secretion GO:0046879 128 0.010
mitotic cell cycle process GO:1903047 159 0.010
regulation of peptide transport GO:0090087 91 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
cell cell junction organization GO:0045216 72 0.010
regulation of cell motility GO:2000145 236 0.010
protein import GO:0017038 101 0.010
negative regulation of cell cycle GO:0045786 123 0.010
positive regulation of smooth muscle cell migration GO:0014911 4 0.010
appendage morphogenesis GO:0035107 149 0.010
protein autophosphorylation GO:0046777 61 0.010
striated muscle tissue development GO:0014706 293 0.010
anion transport GO:0006820 177 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
muscle tissue development GO:0060537 308 0.010
cell growth GO:0016049 130 0.010
ear development GO:0043583 200 0.010

Lrfn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.021
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
musculoskeletal system disease DOID:17 0 0.010
inherited metabolic disorder DOID:655 0 0.010