Mus musculus

106 known processes

Ireb2

iron responsive element binding protein 2

(Aliases: Irp2,DKFZp564D1164,D9Ertd85e)

Ireb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular chemical homeostasis GO:0055082 215 0.410
ubiquitin dependent protein catabolic process GO:0006511 129 0.344
protein modification by small protein conjugation or removal GO:0070647 207 0.308
cellular macromolecule catabolic process GO:0044265 206 0.292
modification dependent macromolecule catabolic process GO:0043632 133 0.287
macromolecule catabolic process GO:0009057 281 0.274
small gtpase mediated signal transduction GO:0007264 97 0.268
protein catabolic process GO:0030163 221 0.224
cellular protein catabolic process GO:0044257 155 0.219
cation homeostasis GO:0055080 212 0.219
dna metabolic process GO:0006259 303 0.207
metal ion homeostasis GO:0055065 189 0.207
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.203
modification dependent protein catabolic process GO:0019941 133 0.189
protein modification by small protein conjugation GO:0032446 187 0.177
positive regulation of cellular catabolic process GO:0031331 148 0.165
ras protein signal transduction GO:0007265 77 0.153
cellular amino acid metabolic process GO:0006520 103 0.152
neuron apoptotic process GO:0051402 142 0.149
cellular homeostasis GO:0019725 240 0.148
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.142
proteasomal protein catabolic process GO:0010498 98 0.135
regulation of cellular protein catabolic process GO:1903362 61 0.126
aromatic compound catabolic process GO:0019439 286 0.119
transmembrane transport GO:0055085 412 0.118
organelle assembly GO:0070925 177 0.117
cell type specific apoptotic process GO:0097285 268 0.117
cell division GO:0051301 120 0.117
neuron death GO:0070997 154 0.112
cytokine production GO:0001816 319 0.111
regulation of defense response GO:0031347 233 0.110
cellular metal ion homeostasis GO:0006875 151 0.108
positive regulation of proteolysis GO:0045862 85 0.107
transition metal ion homeostasis GO:0055076 54 0.098
positive regulation of cellular protein catabolic process GO:1903364 34 0.093
regulation of cellular catabolic process GO:0031329 242 0.089
heterocycle catabolic process GO:0046700 280 0.085
regulation of innate immune response GO:0045088 91 0.080
transition metal ion transport GO:0000041 38 0.079
regulation of protein catabolic process GO:0042176 108 0.078
protein localization to organelle GO:0033365 185 0.077
cellular response to dna damage stimulus GO:0006974 207 0.074
inorganic ion transmembrane transport GO:0098660 234 0.074
axonogenesis GO:0007409 274 0.073
cellular amine metabolic process GO:0044106 44 0.073
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.071
regulation of cellular ketone metabolic process GO:0010565 66 0.069
protein ubiquitination GO:0016567 171 0.068
developmental maturation GO:0021700 193 0.068
stem cell differentiation GO:0048863 268 0.065
lymphocyte homeostasis GO:0002260 64 0.064
gland development GO:0048732 330 0.061
regulation of organelle organization GO:0033043 289 0.058
negative regulation of neuron death GO:1901215 98 0.058
negative regulation of cell cycle GO:0045786 123 0.057
protein polyubiquitination GO:0000209 33 0.055
regulation of cellular amine metabolic process GO:0033238 20 0.053
response to oxidative stress GO:0006979 123 0.050
defense response to other organism GO:0098542 197 0.049
cellular response to external stimulus GO:0071496 88 0.049
positive regulation of innate immune response GO:0045089 80 0.048
ion transmembrane transport GO:0034220 361 0.048
regionalization GO:0003002 337 0.048
nitrogen compound transport GO:0071705 271 0.047
organophosphate catabolic process GO:0046434 232 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
chromatin modification GO:0016568 187 0.044
chemotaxis GO:0006935 247 0.043
regulation of cell cycle GO:0051726 281 0.043
digestive tract morphogenesis GO:0048546 147 0.042
negative regulation of cell cycle process GO:0010948 69 0.042
rho protein signal transduction GO:0007266 32 0.042
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.042
cell maturation GO:0048469 127 0.042
purine nucleotide metabolic process GO:0006163 302 0.042
amine metabolic process GO:0009308 45 0.040
organelle localization GO:0051640 179 0.040
centrosome duplication GO:0051298 16 0.039
regulation of neuron apoptotic process GO:0043523 122 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.039
regulation of chromosome organization GO:0033044 83 0.039
purine nucleoside metabolic process GO:0042278 241 0.039
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.038
cellular transition metal ion homeostasis GO:0046916 32 0.038
response to extracellular stimulus GO:0009991 127 0.037
organic cyclic compound catabolic process GO:1901361 295 0.037
posttranscriptional regulation of gene expression GO:0010608 155 0.037
positive regulation of cell development GO:0010720 237 0.036
nucleoside catabolic process GO:0009164 206 0.035
carbohydrate derivative biosynthetic process GO:1901137 183 0.035
negative regulation of dna dependent dna replication GO:2000104 1 0.035
histone modification GO:0016570 159 0.035
regulation of neuron differentiation GO:0045664 281 0.034
innate immune response GO:0045087 157 0.034
gene silencing GO:0016458 38 0.034
regulation of protein localization GO:0032880 231 0.034
ribose phosphate metabolic process GO:0019693 291 0.033
stem cell development GO:0048864 219 0.032
maintenance of location GO:0051235 89 0.032
regulation of cellular component size GO:0032535 121 0.032
organonitrogen compound biosynthetic process GO:1901566 192 0.031
mitotic cell cycle process GO:1903047 159 0.031
meiotic cell cycle process GO:1903046 77 0.031
cellularization GO:0007349 1 0.031
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
forebrain development GO:0030900 302 0.029
regulation of neuron death GO:1901214 134 0.028
purine containing compound metabolic process GO:0072521 311 0.027
establishment of protein localization to organelle GO:0072594 118 0.026
cellular divalent inorganic cation homeostasis GO:0072503 127 0.026
regulation of cytokine production GO:0001817 266 0.026
microtubule based process GO:0007017 236 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
negative regulation of neuron apoptotic process GO:0043524 92 0.025
cation transmembrane transport GO:0098655 266 0.025
myeloid leukocyte differentiation GO:0002573 119 0.024
appendage development GO:0048736 166 0.024
myeloid cell differentiation GO:0030099 233 0.024
multicellular organismal homeostasis GO:0048871 164 0.024
regulation of cell projection organization GO:0031344 206 0.024
skeletal system development GO:0001501 356 0.024
compound eye development GO:0048749 1 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
chromosome segregation GO:0007059 48 0.023
cellular ion homeostasis GO:0006873 165 0.023
regulation of cell migration GO:0030334 219 0.023
protein modification by small protein removal GO:0070646 21 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
endocytosis GO:0006897 168 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.023
cellular ketone metabolic process GO:0042180 84 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
oogenesis GO:0048477 56 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
cognition GO:0050890 149 0.022
leukocyte homeostasis GO:0001776 79 0.022
inorganic cation transmembrane transport GO:0098662 207 0.022
cation transport GO:0006812 399 0.021
regulation of inflammatory response GO:0050727 147 0.021
negative regulation of immune system process GO:0002683 209 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
synaptic transmission GO:0007268 329 0.021
regulation of ossification GO:0030278 112 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
defense response to bacterium GO:0042742 119 0.020
positive regulation of secretion GO:0051047 130 0.020
iron ion homeostasis GO:0055072 36 0.020
response to radiation GO:0009314 165 0.020
phagocytosis GO:0006909 66 0.020
glycerolipid biosynthetic process GO:0045017 50 0.020
negative regulation of protein modification process GO:0031400 163 0.020
digestive system development GO:0055123 200 0.020
leukocyte differentiation GO:0002521 342 0.019
response to nutrient levels GO:0031667 109 0.019
organophosphate biosynthetic process GO:0090407 122 0.019
regulation of ion transport GO:0043269 215 0.018
regulation of cellular response to stress GO:0080135 159 0.018
regulation of protein transport GO:0051223 163 0.018
lung development GO:0030324 164 0.018
erk1 and erk2 cascade GO:0070371 77 0.018
female gamete generation GO:0007292 74 0.018
negative regulation of growth GO:0045926 99 0.018
wound healing GO:0042060 157 0.018
germ cell development GO:0007281 185 0.018
exocytosis GO:0006887 121 0.018
snrna 3 end processing GO:0034472 1 0.018
mitotic cell cycle GO:0000278 195 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.018
response to growth factor GO:0070848 198 0.017
rna 3 end processing GO:0031123 20 0.017
nucleoside monophosphate metabolic process GO:0009123 85 0.017
positive regulation of cell motility GO:2000147 116 0.017
nuclear division GO:0000280 158 0.017
rna catabolic process GO:0006401 29 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
sensory organ morphogenesis GO:0090596 242 0.017
mapk cascade GO:0000165 281 0.017
negative regulation of synapse assembly GO:0051964 3 0.017
gastrulation GO:0007369 116 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.016
homeostasis of number of cells GO:0048872 210 0.016
divalent inorganic cation transport GO:0072511 178 0.016
positive regulation of cytokine production GO:0001819 174 0.016
ossification GO:0001503 216 0.016
meiotic cell cycle GO:0051321 122 0.016
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.016
cellular response to extracellular stimulus GO:0031668 81 0.016
establishment of organelle localization GO:0051656 122 0.016
regulation of erk1 and erk2 cascade GO:0070372 71 0.015
ncrna 3 end processing GO:0043628 2 0.015
peptidyl amino acid modification GO:0018193 336 0.015
regulation of proteolysis GO:0030162 164 0.015
response to organonitrogen compound GO:0010243 246 0.015
blastocyst formation GO:0001825 33 0.015
chromatin organization GO:0006325 206 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
internal protein amino acid acetylation GO:0006475 42 0.015
neuron projection guidance GO:0097485 141 0.015
odontogenesis GO:0042476 78 0.014
peptidyl lysine modification GO:0018205 77 0.014
regulation of mapk cascade GO:0043408 248 0.014
trophectodermal cell differentiation GO:0001829 21 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.014
antibacterial peptide production GO:0002778 2 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
regulation of membrane potential GO:0042391 192 0.014
negative regulation of protein metabolic process GO:0051248 282 0.014
regulation of neuron projection development GO:0010975 169 0.014
actin cytoskeleton organization GO:0030036 220 0.014
mitotic nuclear division GO:0007067 48 0.014
muscle system process GO:0003012 141 0.014
myeloid leukocyte activation GO:0002274 83 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
epithelial cell development GO:0002064 159 0.014
stem cell maintenance GO:0019827 130 0.014
positive regulation of cell migration GO:0030335 109 0.014
negative regulation of mitotic cell cycle GO:0045930 58 0.013
anatomical structure homeostasis GO:0060249 145 0.013
regulation of kinase activity GO:0043549 249 0.013
positive regulation of organelle organization GO:0010638 128 0.013
protein acylation GO:0043543 64 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
regulation of secretion GO:0051046 274 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
regulation of cell cycle process GO:0010564 160 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
response to organic cyclic compound GO:0014070 198 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
limb morphogenesis GO:0035108 149 0.013
ribonucleoside monophosphate catabolic process GO:0009158 57 0.013
response to steroid hormone GO:0048545 56 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
muscle cell differentiation GO:0042692 261 0.013
positive regulation of nervous system development GO:0051962 221 0.013
positive regulation of protein modification process GO:0031401 299 0.013
protein deubiquitination GO:0016579 19 0.012
regulation of histone modification GO:0031056 56 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
oocyte axis specification GO:0007309 2 0.012
body fluid secretion GO:0007589 53 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
metencephalon development GO:0022037 89 0.012
maintenance of location in cell GO:0051651 24 0.012
tube formation GO:0035148 140 0.012
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.012
covalent chromatin modification GO:0016569 163 0.012
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.012
embryonic appendage morphogenesis GO:0035113 126 0.012
establishment or maintenance of polarity of embryonic epithelium GO:0016332 1 0.012
osteoclast differentiation GO:0030316 62 0.012
digestive tract development GO:0048565 190 0.012
positive regulation of protein catabolic process GO:0045732 60 0.012
regulation of osteoblast differentiation GO:0045667 67 0.012
asymmetric neuroblast division GO:0055059 1 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
epithelial cell proliferation GO:0050673 174 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
respiratory system development GO:0060541 190 0.011
positive regulation of defense response GO:0031349 124 0.011
regulation of chromatin modification GO:1903308 57 0.011
intra s dna damage checkpoint GO:0031573 4 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
blood circulation GO:0008015 195 0.011
translation GO:0006412 93 0.011
appendage morphogenesis GO:0035107 149 0.011
negative regulation of dna replication GO:0008156 4 0.011
dna integrity checkpoint GO:0031570 28 0.011
regulation of body fluid levels GO:0050878 162 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
phosphatidylinositol biosynthetic process GO:0006661 15 0.011
mammary gland epithelial cell proliferation GO:0033598 24 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
regulation of histone acetylation GO:0035065 19 0.011
transforming growth factor beta2 production GO:0032906 2 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
defense response to gram positive bacterium GO:0050830 50 0.011
learning or memory GO:0007611 148 0.011
rna processing GO:0006396 105 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.011
response to lipopolysaccharide GO:0032496 128 0.011
response to transition metal nanoparticle GO:1990267 11 0.011
dna repair GO:0006281 107 0.011
respiratory tube development GO:0030323 167 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
female gonad development GO:0008585 71 0.011
positive regulation of growth GO:0045927 104 0.010
nucleotide metabolic process GO:0009117 332 0.010
response to light stimulus GO:0009416 135 0.010
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.010
connective tissue development GO:0061448 179 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
mrna catabolic process GO:0006402 22 0.010
calcium ion homeostasis GO:0055074 127 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
zinc ion transmembrane transport GO:0071577 10 0.010

Ireb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
central nervous system disease DOID:331 0 0.016
neurodegenerative disease DOID:1289 0 0.016
integumentary system disease DOID:16 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014