Mus musculus

134 known processes

Shank1

SH3/ankyrin domain gene 1

Shank1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inorganic cation transmembrane transport GO:0098662 207 0.286
cation transmembrane transport GO:0098655 266 0.232
camera type eye development GO:0043010 266 0.216
ion transmembrane transport GO:0034220 361 0.176
regulation of secretion by cell GO:1903530 249 0.175
response to organic cyclic compound GO:0014070 198 0.153
nitrogen compound transport GO:0071705 271 0.152
forebrain development GO:0030900 302 0.144
Mouse
transmembrane transport GO:0055085 412 0.141
cation transport GO:0006812 399 0.130
regulation of secretion GO:0051046 274 0.116
cellular homeostasis GO:0019725 240 0.110
Mouse
peptide transport GO:0015833 133 0.103
cell adhesion GO:0007155 329 0.094
regulation of interleukin 8 secretion GO:2000482 2 0.092
inorganic ion transmembrane transport GO:0098660 234 0.092
skeletal system development GO:0001501 356 0.091
response to organonitrogen compound GO:0010243 246 0.087
peptide secretion GO:0002790 114 0.086
regulation of peptide transport GO:0090087 91 0.085
regulation of anatomical structure size GO:0090066 178 0.084
gland development GO:0048732 330 0.083
organic anion transport GO:0015711 137 0.082
epithelial tube morphogenesis GO:0060562 303 0.081
Mouse
rhythmic process GO:0048511 174 0.075
Worm
skeletal system morphogenesis GO:0048705 203 0.075
cartilage development GO:0051216 140 0.075
nucleobase containing small molecule metabolic process GO:0055086 352 0.073
central nervous system morphogenesis GO:0021551 2 0.073
regulation of cellular amine metabolic process GO:0033238 20 0.072
connective tissue development GO:0061448 179 0.072
t cell differentiation GO:0030217 174 0.072
cell fate commitment GO:0045165 210 0.071
amine metabolic process GO:0009308 45 0.068
cellular response to organonitrogen compound GO:0071417 145 0.067
chondrocyte differentiation GO:0002062 72 0.065
nucleoside phosphate metabolic process GO:0006753 338 0.065
lung development GO:0030324 164 0.063
anion transport GO:0006820 177 0.062
mammary gland epithelium development GO:0061180 65 0.060
cellular response to lipid GO:0071396 145 0.060
response to pain GO:0048265 26 0.059
insulin secretion GO:0030073 89 0.059
negative regulation of nervous system development GO:0051961 156 0.058
atrial cardiac muscle cell differentiation GO:0055011 2 0.058
positive regulation of cell cycle GO:0045787 92 0.057
mitotic cell cycle GO:0000278 195 0.057
negative regulation of neuron differentiation GO:0045665 101 0.057
amino acid transport GO:0006865 61 0.055
sensory perception GO:0007600 245 0.055
Human
mapk cascade GO:0000165 281 0.055
Mouse
lymphocyte differentiation GO:0030098 242 0.055
locomotory behavior GO:0007626 195 0.055
Mouse
purine containing compound metabolic process GO:0072521 311 0.055
regulation of cell cycle GO:0051726 281 0.054
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.054
extracellular matrix organization GO:0030198 147 0.054
cellular response to hormone stimulus GO:0032870 150 0.053
extracellular structure organization GO:0043062 148 0.053
ribose phosphate metabolic process GO:0019693 291 0.052
carbohydrate homeostasis GO:0033500 128 0.052
cell type specific apoptotic process GO:0097285 268 0.051
digestive system development GO:0055123 200 0.051
nucleotide metabolic process GO:0009117 332 0.051
leukocyte differentiation GO:0002521 342 0.049
negative regulation of cell proliferation GO:0008285 296 0.049
somatotropin secreting cell differentiation GO:0060126 4 0.049
positive regulation of growth GO:0045927 104 0.048
regulation of voltage gated calcium channel activity GO:1901385 4 0.048
respiratory system development GO:0060541 190 0.048
single organism cell adhesion GO:0098602 156 0.048
circulatory system process GO:0003013 197 0.047
response to steroid hormone GO:0048545 56 0.047
ossification GO:0001503 216 0.047
protein localization to membrane GO:0072657 108 0.046
Mouse
cellular amino acid metabolic process GO:0006520 103 0.045
cell growth GO:0016049 130 0.045
regulation of peptide hormone secretion GO:0090276 75 0.045
regulation of ossification GO:0030278 112 0.045
response to molecule of bacterial origin GO:0002237 143 0.045
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.044
peptide hormone secretion GO:0030072 109 0.044
regulation of membrane potential GO:0042391 192 0.043
globus pallidus development GO:0021759 2 0.042
positive regulation of interleukin 8 production GO:0032757 2 0.042
g protein coupled receptor signaling pathway GO:0007186 243 0.042
t cell activation GO:0042110 289 0.042
glucose homeostasis GO:0042593 128 0.042
ventricular cardiac myofibril assembly GO:0055005 3 0.041
cellular chemical homeostasis GO:0055082 215 0.041
carbohydrate metabolic process GO:0005975 230 0.041
learning GO:0007612 98 0.040
morphogenesis of embryonic epithelium GO:0016331 159 0.040
Mouse
regulation of interleukin 8 production GO:0032677 3 0.040
negative regulation of cellular component organization GO:0051129 194 0.039
homeostasis of number of cells GO:0048872 210 0.039
respiratory tube development GO:0030323 167 0.039
epithelial cell development GO:0002064 159 0.039
regulation of peptide secretion GO:0002791 77 0.039
paraxial mesodermal cell differentiation GO:0048342 2 0.039
response to transforming growth factor beta GO:0071559 88 0.039
epidermis development GO:0008544 187 0.038
organelle localization GO:0051640 179 0.038
regulation of ion transmembrane transport GO:0034765 119 0.038
spermatogenesis GO:0007283 284 0.038
membrane organization GO:0061024 245 0.038
Mouse
regulation of cellular catabolic process GO:0031329 242 0.038
organic hydroxy compound metabolic process GO:1901615 203 0.037
hormone secretion GO:0046879 128 0.037
positive regulation of kinase activity GO:0033674 155 0.037
response to extracellular stimulus GO:0009991 127 0.037
cell division GO:0051301 120 0.037
interleukin 8 secretion GO:0072606 3 0.037
potassium ion transport GO:0006813 52 0.036
hexose metabolic process GO:0019318 98 0.036
digestion GO:0007586 40 0.036
carbohydrate derivative biosynthetic process GO:1901137 183 0.036
negative regulation of growth GO:0045926 99 0.036
regulation of cell cycle process GO:0010564 160 0.035
ribose phosphate biosynthetic process GO:0046390 59 0.035
regulation of hormone levels GO:0010817 211 0.035
purine containing compound biosynthetic process GO:0072522 70 0.035
positive regulation of nervous system development GO:0051962 221 0.035
Mouse Rat
male sex differentiation GO:0046661 109 0.035
regulation of cellular component size GO:0032535 121 0.035
regulation of fat cell differentiation GO:0045598 81 0.035
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.034
positive regulation of interleukin 8 secretion GO:2000484 1 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.034
purine nucleotide biosynthetic process GO:0006164 65 0.034
blood circulation GO:0008015 195 0.034
response to starvation GO:0042594 65 0.034
negative regulation of axon extension GO:0030517 19 0.034
regulation of transmembrane transport GO:0034762 128 0.034
lateral inhibition GO:0046331 1 0.034
spinal cord development GO:0021510 81 0.033
regulation of transforming growth factor beta2 production GO:0032909 2 0.033
multicellular organism growth GO:0035264 161 0.033
response to light stimulus GO:0009416 135 0.033
amide transport GO:0042886 138 0.033
negative regulation of wnt signaling pathway GO:0030178 73 0.032
renal system development GO:0072001 225 0.032
purine nucleotide metabolic process GO:0006163 302 0.032
organophosphate biosynthetic process GO:0090407 122 0.032
organic acid transport GO:0015849 101 0.032
actin cytoskeleton organization GO:0030036 220 0.032
learning or memory GO:0007611 148 0.032
lens epithelial cell proliferation GO:0097166 1 0.032
oxidation reduction process GO:0055114 342 0.032
cyclic nucleotide metabolic process GO:0009187 59 0.032
organ growth GO:0035265 117 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
ras protein signal transduction GO:0007265 77 0.031
regulation of epithelial cell proliferation GO:0050678 141 0.031
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.031
regulation of establishment of protein localization GO:0070201 181 0.031
sodium ion transport GO:0006814 73 0.030
menarche GO:0042696 1 0.030
renal vesicle induction GO:0072034 3 0.030
cellular protein complex assembly GO:0043623 116 0.030
posttranscriptional regulation of gene expression GO:0010608 155 0.030
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.030
cellular response to organic cyclic compound GO:0071407 87 0.030
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.030
regulation of neuron differentiation GO:0045664 281 0.030
Mouse Rat
regulation of cell growth GO:0001558 91 0.030
transforming growth factor beta2 production GO:0032906 2 0.030
regulation of chondrocyte differentiation GO:0032330 33 0.030
regulation of protein transport GO:0051223 163 0.029
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.029
cognition GO:0050890 149 0.029
bone development GO:0060348 120 0.029
kidney development GO:0001822 213 0.029
regulation of ion transmembrane transporter activity GO:0032412 54 0.029
cerebellum development GO:0021549 77 0.029
regulation of blood pressure GO:0008217 93 0.029
sodium ion transmembrane transport GO:0035725 49 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
circadian rhythm GO:0007623 114 0.028
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.028
regulation of heart contraction GO:0008016 77 0.028
positive regulation of transcription via serum response element binding GO:0010735 1 0.028
positive regulation of secretion by cell GO:1903532 114 0.028
regulation of purine nucleotide metabolic process GO:1900542 169 0.028
nuclear division GO:0000280 158 0.028
embryonic organ morphogenesis GO:0048562 276 0.027
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.027
atrioventricular node cell development GO:0060928 2 0.027
cell activation involved in immune response GO:0002263 126 0.027
microtubule based process GO:0007017 236 0.027
astrocyte fate commitment GO:0060018 4 0.027
outflow tract morphogenesis GO:0003151 53 0.027
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
regulation of cell projection organization GO:0031344 206 0.027
Mouse Rat
carboxylic acid transport GO:0046942 100 0.027
energy derivation by oxidation of organic compounds GO:0015980 77 0.027
ventral spinal cord interneuron fate determination GO:0060580 1 0.027
regulation of cell activation GO:0050865 289 0.026
response to growth factor GO:0070848 198 0.026
atrioventricular node cell fate commitment GO:0060929 1 0.026
single organismal cell cell adhesion GO:0016337 131 0.026
response to radiation GO:0009314 165 0.026
regulation of canonical wnt signaling pathway GO:0060828 82 0.026
regulation of osteoblast differentiation GO:0045667 67 0.026
organelle fission GO:0048285 170 0.026
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.026
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
neuron migration GO:0001764 122 0.026
regulation of circadian rhythm GO:0042752 58 0.026
epithelial cell proliferation GO:0050673 174 0.026
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.026
striated muscle cell proliferation GO:0014855 39 0.025
forebrain neuron differentiation GO:0021879 52 0.025
Mouse
rho protein signal transduction GO:0007266 32 0.025
regulation of cell adhesion GO:0030155 154 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.025
regulation of body fluid levels GO:0050878 162 0.025
mammary gland morphogenesis GO:0060443 54 0.025
developmental programmed cell death GO:0010623 41 0.025
compound eye development GO:0048749 1 0.025
negative regulation of neuron projection development GO:0010977 50 0.025
hindbrain development GO:0030902 128 0.024
cellular ketone metabolic process GO:0042180 84 0.024
stem cell differentiation GO:0048863 268 0.024
purine ribonucleotide biosynthetic process GO:0009152 59 0.024
positive regulation of nucleotide metabolic process GO:0045981 114 0.024
negative regulation of cell development GO:0010721 169 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.024
interleukin 8 production GO:0032637 4 0.024
myeloid cell differentiation GO:0030099 233 0.023
regulation of neuron projection development GO:0010975 169 0.023
Mouse Rat
regulation of glutamate secretion GO:0014048 3 0.023
developmental growth involved in morphogenesis GO:0060560 138 0.023
establishment of planar polarity GO:0001736 28 0.023
nucleotide biosynthetic process GO:0009165 78 0.023
regulation of response to wounding GO:1903034 189 0.023
heart morphogenesis GO:0003007 178 0.023
establishment of tissue polarity GO:0007164 28 0.023
telencephalon development GO:0021537 186 0.023
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.023
canonical wnt signaling pathway GO:0060070 130 0.023
camp metabolic process GO:0046058 40 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
cell cell signaling involved in cell fate commitment GO:0045168 35 0.022
response to nutrient levels GO:0031667 109 0.022
response to lipopolysaccharide GO:0032496 128 0.022
embryonic skeletal system development GO:0048706 120 0.022
calcium ion transmembrane transport GO:0070588 85 0.022
regulation of lipid metabolic process GO:0019216 118 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.022
atrioventricular node cell differentiation GO:0060922 2 0.022
regulation of cartilage development GO:0061035 44 0.022
forebrain generation of neurons GO:0021872 63 0.022
Mouse
regionalization GO:0003002 337 0.022
endocrine pancreas development GO:0031018 29 0.022
negative regulation of phosphate metabolic process GO:0045936 184 0.022
positive regulation of gtp catabolic process GO:0033126 85 0.022
cellular glucose homeostasis GO:0001678 52 0.022
ribonucleotide biosynthetic process GO:0009260 59 0.022
cell fate determination involved in pattern specification GO:0060582 1 0.022
cellular response to extracellular stimulus GO:0031668 81 0.022
regulation of metal ion transport GO:0010959 106 0.021
cellular calcium ion homeostasis GO:0006874 119 0.021
microtubule cytoskeleton organization GO:0000226 157 0.021
b cell activation GO:0042113 161 0.021
purkinje myocyte differentiation GO:0003168 1 0.021
response to peptide GO:1901652 136 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
protein catabolic process GO:0030163 221 0.021
regulation of extent of cell growth GO:0061387 52 0.021
negative regulation of synapse assembly GO:0051964 3 0.021
protein localization to plasma membrane GO:0072659 57 0.021
intracellular protein transport GO:0006886 204 0.021
cellular carbohydrate metabolic process GO:0044262 119 0.021
septum transversum development GO:0003343 2 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
gastrulation GO:0007369 116 0.021
biological phase GO:0044848 20 0.021
regulation of system process GO:0044057 200 0.021
positive regulation of peptide secretion GO:0002793 33 0.021
cellular ion homeostasis GO:0006873 165 0.021
digestive tract morphogenesis GO:0048546 147 0.021
glucose metabolic process GO:0006006 92 0.021
multicellular organismal signaling GO:0035637 91 0.021
cellular response to molecule of bacterial origin GO:0071219 83 0.020
nephron tubule development GO:0072080 84 0.020
actin filament organization GO:0007015 113 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
cellular lipid metabolic process GO:0044255 323 0.020
nuclear transport GO:0051169 139 0.020
inner medullary collecting duct development GO:0072061 2 0.020
blastocyst development GO:0001824 80 0.020
multicellular organismal response to stress GO:0033555 62 0.020
Mouse
regulation of cell motility GO:2000145 236 0.020
multi multicellular organism process GO:0044706 109 0.020
dna metabolic process GO:0006259 303 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
cellular response to external stimulus GO:0071496 88 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.020
embryonic heart tube development GO:0035050 65 0.020
endocrine system development GO:0035270 98 0.020
regulation of cardioblast differentiation GO:0051890 3 0.020
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.020
protein ubiquitination GO:0016567 171 0.020
regulation of protein catabolic process GO:0042176 108 0.020
regulation of wnt signaling pathway GO:0030111 123 0.019
regulation of b cell activation GO:0050864 81 0.019
lipid localization GO:0010876 126 0.019
nucleoside metabolic process GO:0009116 246 0.019
regulation of organelle organization GO:0033043 289 0.019
macromolecule catabolic process GO:0009057 281 0.019
regulation of homeostatic process GO:0032844 182 0.019
cellular response to starvation GO:0009267 57 0.019
regulation of hormone secretion GO:0046883 88 0.019
striated muscle tissue development GO:0014706 293 0.019
regulation of cell migration GO:0030334 219 0.019
gonad development GO:0008406 141 0.019
closure of optic fissure GO:0061386 2 0.019
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.019
maintenance of cell number GO:0098727 3 0.019
positive regulation of cell development GO:0010720 237 0.019
Mouse Rat
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 3 0.019
organophosphate catabolic process GO:0046434 232 0.019
cellular response to monosaccharide stimulus GO:0071326 47 0.019
regulation of testosterone biosynthetic process GO:2000224 2 0.019
pulmonary myocardium development GO:0003350 3 0.019
pancreatic pp cell differentiation GO:0003312 2 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
acid secretion GO:0046717 33 0.019
regulation of hair cycle GO:0042634 11 0.019
cervix development GO:0060067 2 0.019
reactive oxygen species metabolic process GO:0072593 84 0.018
synapse organization GO:0050808 125 0.018
Mouse Rat
regulation of cellular response to growth factor stimulus GO:0090287 82 0.018
phospholipid metabolic process GO:0006644 87 0.018
blood vessel morphogenesis GO:0048514 285 0.018
developmental maturation GO:0021700 193 0.018
Rat
proepicardium development GO:0003342 2 0.018
endocardial cell differentiation GO:0060956 4 0.018
regulation of cell size GO:0008361 72 0.018
response to monosaccharide GO:0034284 67 0.018
anatomical structure homeostasis GO:0060249 145 0.018
transmission of nerve impulse GO:0019226 76 0.018
cytokine production GO:0001816 319 0.018
digestive tract development GO:0048565 190 0.018
negative regulation of cell growth GO:0030308 44 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
intestinal epithelial structure maintenance GO:0060729 4 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
cellular response to glucose stimulus GO:0071333 45 0.018
muscle cell proliferation GO:0033002 52 0.018
regulation of anagen GO:0051884 1 0.018
cardiac chamber development GO:0003205 108 0.018
response to peptide hormone GO:0043434 127 0.018
telencephalon cell migration GO:0022029 55 0.017
associative learning GO:0008306 61 0.017
anion transmembrane transport GO:0098656 71 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
positive regulation of hair cycle GO:0042635 7 0.017
regulation of establishment of planar polarity GO:0090175 28 0.017
regulation of cell cycle phase transition GO:1901987 77 0.017
protein targeting GO:0006605 143 0.017
leukocyte homeostasis GO:0001776 79 0.017
regulation of organ growth GO:0046620 61 0.017
muscle contraction GO:0006936 101 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.017
Mouse
lung epithelium development GO:0060428 37 0.017
axonogenesis GO:0007409 274 0.017
protein localization to nucleus GO:0034504 121 0.017
establishment of protein localization to organelle GO:0072594 118 0.017
embryonic epithelial tube formation GO:0001838 130 0.017
Mouse
meiotic cell cycle GO:0051321 122 0.017
nucleoside phosphate biosynthetic process GO:1901293 79 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
axis elongation involved in somitogenesis GO:0090245 4 0.017
negative regulation of gastrulation GO:2000542 3 0.017
adult behavior GO:0030534 135 0.017
Human Mouse
pallium development GO:0021543 120 0.017
positive regulation of gtpase activity GO:0043547 85 0.017
positive regulation of peptidase activity GO:0010952 49 0.017
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.017
cyclic purine nucleotide metabolic process GO:0052652 43 0.017
divalent inorganic cation transport GO:0072511 178 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
muscle tissue development GO:0060537 308 0.017
fat cell differentiation GO:0045444 160 0.016
immune response regulating signaling pathway GO:0002764 125 0.016
kidney epithelium development GO:0072073 121 0.016
type b pancreatic cell proliferation GO:0044342 10 0.016
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
body fluid secretion GO:0007589 53 0.016
cellular amine metabolic process GO:0044106 44 0.016
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.016
embryonic skeletal system morphogenesis GO:0048704 91 0.016
regulation of organ morphogenesis GO:2000027 144 0.016
action potential GO:0001508 78 0.016
negative regulation of ossification GO:0030279 49 0.016
plasma cell differentiation GO:0002317 3 0.016
cation homeostasis GO:0055080 212 0.016
wound healing GO:0042060 157 0.016
gtp metabolic process GO:0046039 144 0.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.016
cardiac muscle cell differentiation GO:0055007 69 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.016
mesoderm development GO:0007498 100 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
neuroblast differentiation GO:0014016 2 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
positive regulation of protein modification process GO:0031401 299 0.016
cellular response to nutrient levels GO:0031669 64 0.016
immune response activating signal transduction GO:0002757 116 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.016
limbic system development GO:0021761 72 0.015
atrial cardiac muscle cell development GO:0055014 2 0.015
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.015
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.015
memory GO:0007613 58 0.015
renal outer medulla development GO:0072054 2 0.015
smoothened signaling pathway GO:0007224 105 0.015
mesenchymal cell development GO:0014031 93 0.015
wnt signaling pathway GO:0016055 188 0.015
regulation of axon extension GO:0030516 43 0.015
regulation of protein complex assembly GO:0043254 83 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
mesenchymal cell differentiation GO:0048762 107 0.015
negative regulation of cell cycle GO:0045786 123 0.015
mesonephric duct morphogenesis GO:0072180 4 0.015
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.015
positive regulation of secretion GO:0051047 130 0.015
determination of left right symmetry GO:0007368 80 0.015
negative regulation of fat cell differentiation GO:0045599 36 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.015
apoptotic signaling pathway GO:0097190 306 0.015
renal tubule morphogenesis GO:0061333 72 0.015
regulation of proteolysis GO:0030162 164 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
endocytosis GO:0006897 168 0.015
tissue homeostasis GO:0001894 115 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
outer medullary collecting duct development GO:0072060 1 0.015
spemann organizer formation GO:0060061 2 0.015
regulation of mitotic cell cycle phase transition GO:1901990 73 0.015
peptidyl threonine modification GO:0018210 31 0.015
protein kinase b signaling GO:0043491 74 0.015
lipid biosynthetic process GO:0008610 179 0.015
positive regulation of rho gtpase activity GO:0032321 41 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.014
glutamate secretion GO:0014047 8 0.014
monosaccharide metabolic process GO:0005996 106 0.014
sulfur compound metabolic process GO:0006790 100 0.014
protein localization to organelle GO:0033365 185 0.014
mesonephric tubule development GO:0072164 94 0.014
response to insulin GO:0032868 100 0.014
spleen development GO:0048536 39 0.014
branching morphogenesis of an epithelial tube GO:0048754 159 0.014
establishment of organelle localization GO:0051656 122 0.014
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.014
cellular protein catabolic process GO:0044257 155 0.014
negative regulation of cytokine production GO:0001818 84 0.014
pancreatic a cell fate commitment GO:0003326 2 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
nuclear import GO:0051170 95 0.014
positive regulation of osteoblast differentiation GO:0045669 34 0.014
pancreas development GO:0031016 57 0.014
ear morphogenesis GO:0042471 118 0.014
hindbrain formation GO:0021576 1 0.014
regulation of mapk cascade GO:0043408 248 0.014
positive regulation of epithelial cell proliferation GO:0050679 68 0.014
forebrain cell migration GO:0021885 58 0.014
paraxial mesodermal cell fate commitment GO:0048343 2 0.014
meiotic nuclear division GO:0007126 115 0.014
divalent metal ion transport GO:0070838 172 0.014
cellular response to peptide GO:1901653 92 0.014
negative regulation of cell projection organization GO:0031345 56 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
positive regulation of cell migration GO:0030335 109 0.014
glycerolipid metabolic process GO:0046486 122 0.014
negative regulation of hormone biosynthetic process GO:0032353 4 0.014
bone mineralization GO:0030282 54 0.014
central nervous system vasculogenesis GO:0022009 3 0.014
cytoplasmic transport GO:0016482 234 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.014
determination of heart left right asymmetry GO:0061371 48 0.014
development of primary male sexual characteristics GO:0046546 88 0.014
sensory organ morphogenesis GO:0090596 242 0.014
somatic stem cell maintenance GO:0035019 47 0.014

Shank1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017