Mus musculus

43 known processes

Wls

wntless homolog (Drosophila)

(Aliases: AI987742,5031439A09Rik,Gpr177,AI173978)

Wls biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
formation of radial glial scaffolds GO:0021943 4 0.641
positive regulation of programmed cell death GO:0043068 218 0.632
neural tube development GO:0021915 160 0.573
Zebrafish
cell adhesion GO:0007155 329 0.547
epithelial tube formation GO:0072175 130 0.497
regulation of cellular response to growth factor stimulus GO:0090287 82 0.454
positive regulation of apoptotic signaling pathway GO:2001235 95 0.417
regulation of cellular ketone metabolic process GO:0010565 66 0.409
embryonic epithelial tube formation GO:0001838 130 0.377
negative regulation of molecular function GO:0044092 258 0.349
epithelial tube morphogenesis GO:0060562 303 0.334
regulation of secretion by cell GO:1903530 249 0.331
Fly
skeletal system development GO:0001501 356 0.323
purine nucleoside metabolic process GO:0042278 241 0.323
response to growth factor GO:0070848 198 0.317
negative regulation of epithelial cell proliferation GO:0050680 64 0.316
leukocyte differentiation GO:0002521 342 0.305
regulation of cell cycle GO:0051726 281 0.294
Worm
negative regulation of cell proliferation GO:0008285 296 0.290
morphogenesis of a branching epithelium GO:0061138 193 0.288
neural tube formation GO:0001841 108 0.286
axis elongation involved in somitogenesis GO:0090245 4 0.283
lymphocyte differentiation GO:0030098 242 0.282
gland development GO:0048732 330 0.274
positive regulation of apoptotic process GO:0043065 217 0.273
apoptotic signaling pathway GO:0097190 306 0.261
positive regulation of cell death GO:0010942 224 0.251
t cell activation GO:0042110 289 0.247
leukocyte proliferation GO:0070661 172 0.240
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.229
regulation of protein localization GO:0032880 231 0.228
Worm Fly
cellular response to growth factor stimulus GO:0071363 197 0.223
immune effector process GO:0002252 321 0.223
negative regulation of cell cycle GO:0045786 123 0.209
t cell proliferation GO:0042098 120 0.208
urogenital system development GO:0001655 261 0.205
hindbrain radial glia guided cell migration GO:0021932 12 0.201
regulation of cellular catabolic process GO:0031329 242 0.200
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.196
epidermis development GO:0008544 187 0.190
camera type eye development GO:0043010 266 0.188
regulation of binding GO:0051098 111 0.186
phagocytosis GO:0006909 66 0.183
protein processing GO:0016485 163 0.180
body morphogenesis GO:0010171 45 0.178
chemotaxis GO:0006935 247 0.177
membrane organization GO:0061024 245 0.175
morphogenesis of embryonic epithelium GO:0016331 159 0.172
regulation of cellular amino acid metabolic process GO:0006521 5 0.171
single organism cell adhesion GO:0098602 156 0.170
digestive tract development GO:0048565 190 0.169
single organismal cell cell adhesion GO:0016337 131 0.165
neuron apoptotic process GO:0051402 142 0.165
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.164
bmp signaling pathway GO:0030509 93 0.162
engulfment of apoptotic cell GO:0043652 3 0.162
regulation of defense response GO:0031347 233 0.160
macromolecule catabolic process GO:0009057 281 0.158
cellular chemical homeostasis GO:0055082 215 0.157
regulation of actin cytoskeleton organization GO:0032956 84 0.156
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.156
renal system development GO:0072001 225 0.153
regulation of hydrolase activity GO:0051336 246 0.150
cellular amino acid metabolic process GO:0006520 103 0.148
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.147
axonogenesis GO:0007409 274 0.146
blood vessel morphogenesis GO:0048514 285 0.145
myeloid cell differentiation GO:0030099 233 0.143
regulation of lymphocyte activation GO:0051249 240 0.143
cytokine production GO:0001816 319 0.139
appendage development GO:0048736 166 0.138
Fly
nucleoside phosphate metabolic process GO:0006753 338 0.137
regulation of t cell activation GO:0050863 170 0.137
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.135
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.134
regulation of t cell proliferation GO:0042129 92 0.132
extrinsic apoptotic signaling pathway GO:0097191 126 0.130
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.130
regulation of protein serine threonine kinase activity GO:0071900 157 0.130
leukocyte migration GO:0050900 124 0.130
protein secretion GO:0009306 111 0.127
Fly
negative regulation of t cell proliferation GO:0042130 38 0.126
regulation of myeloid cell differentiation GO:0045637 96 0.122
mesoderm development GO:0007498 100 0.120
amine metabolic process GO:0009308 45 0.117
regulation of neuron differentiation GO:0045664 281 0.117
stem cell development GO:0048864 219 0.117
regulation of apoptotic signaling pathway GO:2001233 197 0.115
peptidyl tyrosine phosphorylation GO:0018108 143 0.114
muscle system process GO:0003012 141 0.114
dna metabolic process GO:0006259 303 0.113
keratinocyte differentiation GO:0030216 48 0.112
regulation of inflammatory response GO:0050727 147 0.112
inorganic ion transmembrane transport GO:0098660 234 0.112
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.112
response to transforming growth factor beta GO:0071559 88 0.110
response to organonitrogen compound GO:0010243 246 0.109
regulation of canonical wnt signaling pathway GO:0060828 82 0.109
microglia development GO:0014005 2 0.108
mesodermal cell migration GO:0008078 4 0.108
odontogenesis GO:0042476 78 0.107
positive regulation of gtp catabolic process GO:0033126 85 0.107
neuron projection guidance GO:0097485 141 0.107
endodermal cell fate specification GO:0001714 4 0.106
Worm
positive regulation of protein transport GO:0051222 93 0.104
Fly
cognition GO:0050890 149 0.102
digestive tract morphogenesis GO:0048546 147 0.102
microglia differentiation GO:0014004 2 0.100
cell type specific apoptotic process GO:0097285 268 0.100
regulation of protein kinase activity GO:0045859 232 0.099
cell migration involved in gastrulation GO:0042074 13 0.099
positive regulation of mapk cascade GO:0043410 170 0.097
actin cytoskeleton organization GO:0030036 220 0.096
cellular ketone metabolic process GO:0042180 84 0.096
extracellular matrix organization GO:0030198 147 0.096
regulation of neuron projection development GO:0010975 169 0.095
non canonical wnt signaling pathway GO:0035567 33 0.095
Worm
positive regulation of protein phosphorylation GO:0001934 242 0.095
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.092
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.091
embryonic organ morphogenesis GO:0048562 276 0.091
divalent metal ion transport GO:0070838 172 0.090
neuroblast division in subventricular zone GO:0021849 2 0.090
regulation of leukocyte differentiation GO:1902105 159 0.090
negative regulation of cellular protein metabolic process GO:0032269 247 0.090
positive regulation of protein modification process GO:0031401 299 0.088
purine nucleoside triphosphate catabolic process GO:0009146 203 0.088
cellular amine metabolic process GO:0044106 44 0.088
dna recombination GO:0006310 92 0.088
ureteric bud morphogenesis GO:0060675 62 0.088
cellular homeostasis GO:0019725 240 0.086
angiogenesis GO:0001525 201 0.086
negative regulation of hydrolase activity GO:0051346 71 0.086
positive regulation of kinase activity GO:0033674 155 0.086
wnt signaling pathway GO:0016055 188 0.086
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.085
alpha beta t cell differentiation GO:0046632 69 0.085
connective tissue development GO:0061448 179 0.084
neuroblast fate commitment GO:0014017 1 0.084
positive regulation of cell adhesion GO:0045785 80 0.083
mesenchymal cell differentiation GO:0048762 107 0.083
regulation of myeloid leukocyte differentiation GO:0002761 58 0.083
inflammatory response GO:0006954 244 0.082
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.082
peptidyl amino acid modification GO:0018193 336 0.082
regulation of cell activation GO:0050865 289 0.082
regulation of lymphocyte proliferation GO:0050670 117 0.081
myeloid leukocyte differentiation GO:0002573 119 0.081
regulation of organ morphogenesis GO:2000027 144 0.081
response to alcohol GO:0097305 48 0.080
positive regulation of gtpase activity GO:0043547 85 0.080
cellular macromolecule catabolic process GO:0044265 206 0.079
endocytosis GO:0006897 168 0.079
spinal cord development GO:0021510 81 0.079
hair follicle development GO:0001942 85 0.079
epithelial to mesenchymal transition GO:0001837 47 0.078
transmembrane transport GO:0055085 412 0.078
axon guidance GO:0007411 141 0.078
establishment or maintenance of neuroblast polarity GO:0045196 1 0.078
nucleoside triphosphate metabolic process GO:0009141 230 0.078
gastrulation GO:0007369 116 0.078
regulation of establishment of planar polarity GO:0090175 28 0.078
t cell differentiation in thymus GO:0033077 77 0.078
cellular nitrogen compound catabolic process GO:0044270 280 0.077
neuroblast differentiation GO:0014016 2 0.077
positive regulation of cell development GO:0010720 237 0.077
sterol metabolic process GO:0016125 58 0.077
organic acid biosynthetic process GO:0016053 86 0.075
positive regulation of cellular catabolic process GO:0031331 148 0.074
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.074
telencephalon development GO:0021537 186 0.074
hindbrain development GO:0030902 128 0.074
schwann cell proliferation GO:0014010 2 0.073
extracellular structure organization GO:0043062 148 0.073
regulation of nucleoside metabolic process GO:0009118 130 0.072
regulation of proteolysis GO:0030162 164 0.072
cation transport GO:0006812 399 0.072
negative regulation of dna replication GO:0008156 4 0.071
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.071
protein catabolic process GO:0030163 221 0.071
regulation of actin filament based process GO:0032970 99 0.071
canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation GO:0061324 2 0.070
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.070
central nervous system vasculogenesis GO:0022009 3 0.070
foregut regionalization GO:0060423 3 0.069
branching morphogenesis of an epithelial tube GO:0048754 159 0.069
purine ribonucleoside metabolic process GO:0046128 241 0.069
positive regulation of hydrolase activity GO:0051345 148 0.068
negative regulation of cell development GO:0010721 169 0.068
establishment of tissue polarity GO:0007164 28 0.068
regulation of protein secretion GO:0050708 82 0.068
Fly
calcium ion transport GO:0006816 159 0.067
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.067
regulation of neuron apoptotic process GO:0043523 122 0.067
peptidyl tyrosine modification GO:0018212 145 0.066
regulation of secretion GO:0051046 274 0.066
Fly
embryonic appendage morphogenesis GO:0035113 126 0.065
negative regulation of phosphorylation GO:0042326 166 0.065
primary neural tube formation GO:0014020 95 0.065
signal transduction in absence of ligand GO:0038034 55 0.064
sulfur compound biosynthetic process GO:0044272 37 0.064
regulation of leukocyte proliferation GO:0070663 121 0.064
t cell differentiation GO:0030217 174 0.063
cellular response to organic cyclic compound GO:0071407 87 0.063
regulation of hormone levels GO:0010817 211 0.063
blood circulation GO:0008015 195 0.063
pallium development GO:0021543 120 0.063
regulation of b cell tolerance induction GO:0002661 2 0.063
hair cycle GO:0042633 90 0.063
mesenchyme development GO:0060485 152 0.062
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.062
leukocyte mediated immunity GO:0002443 174 0.062
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.062
odontogenesis of dentin containing tooth GO:0042475 66 0.062
positive regulation of protein kinase activity GO:0045860 144 0.062
epithelial cell proliferation GO:0050673 174 0.062
tube formation GO:0035148 140 0.062
kidney development GO:0001822 213 0.061
positive regulation of leukocyte differentiation GO:1902107 86 0.061
neuronal action potential GO:0019228 54 0.061
cerebral cortex development GO:0021987 86 0.061
axon ensheathment GO:0008366 76 0.061
mesoderm formation GO:0001707 62 0.061
glial cell apoptotic process GO:0034349 3 0.061
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.060
organophosphate catabolic process GO:0046434 232 0.060
carboxylic acid biosynthetic process GO:0046394 86 0.060
regulation of response to wounding GO:1903034 189 0.060
retina development in camera type eye GO:0060041 119 0.059
adult behavior GO:0030534 135 0.059
axon target recognition GO:0007412 4 0.059
regulation of cell proliferation involved in outflow tract morphogenesis GO:1901963 2 0.059
pole plasm assembly GO:0007315 2 0.059
positive regulation of transferase activity GO:0051347 167 0.059
regulation of system process GO:0044057 200 0.059
regulation of protein binding GO:0043393 60 0.059
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.059
regulation of cell adhesion GO:0030155 154 0.058
cell growth GO:0016049 130 0.058
stem cell differentiation GO:0048863 268 0.058
positive regulation of lymphocyte activation GO:0051251 140 0.057
calcium ion transmembrane transport GO:0070588 85 0.057
cell fate specification GO:0001708 72 0.057
Worm
ureteric bud development GO:0001657 94 0.057
macrophage differentiation GO:0030225 20 0.057
heterocycle catabolic process GO:0046700 280 0.057
positive regulation of homeostatic process GO:0032846 64 0.057
response to fibroblast growth factor GO:0071774 47 0.056
cell substrate adhesion GO:0031589 130 0.056
learning or memory GO:0007611 148 0.055
jnk cascade GO:0007254 72 0.054
positive regulation of osteoblast proliferation GO:0033690 9 0.054
forebrain development GO:0030900 302 0.054
morphogenesis of a polarized epithelium GO:0001738 37 0.054
chorio allantoic fusion GO:0060710 8 0.054
regulation of kinase activity GO:0043549 249 0.054
l amino acid transport GO:0015807 32 0.053
regulation of transferase activity GO:0051338 263 0.053
mesonephric tubule development GO:0072164 94 0.053
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.052
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.052
central nervous system neuron differentiation GO:0021953 162 0.052
positive regulation of proteolysis GO:0045862 85 0.052
digestive system development GO:0055123 200 0.052
negative regulation of intracellular signal transduction GO:1902532 167 0.051
neural precursor cell proliferation GO:0061351 121 0.051
positive regulation of map kinase activity GO:0043406 84 0.051
regulation of mitotic cell cycle GO:0007346 126 0.051
Worm
protein localization to nucleus GO:0034504 121 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000149 1 0.050
forebrain radial glial cell differentiation GO:0021861 4 0.050
regulation of multi organism process GO:0043900 111 0.049
organic hydroxy compound metabolic process GO:1901615 203 0.049
protein localization to organelle GO:0033365 185 0.049
regulation of establishment of protein localization GO:0070201 181 0.049
Fly
canonical wnt signaling pathway GO:0060070 130 0.048
lung field specification GO:0060424 3 0.048
regulation of peptidase activity GO:0052547 96 0.048
regulation of neuron death GO:1901214 134 0.048
olfactory bulb development GO:0021772 30 0.048
lateral mesoderm morphogenesis GO:0048369 3 0.048
renal tubule development GO:0061326 87 0.048
oocyte anterior posterior axis specification GO:0007314 2 0.048
cell cell junction organization GO:0045216 72 0.047
leukocyte activation involved in immune response GO:0002366 126 0.047
cell matrix adhesion GO:0007160 68 0.047
protein targeting to vacuole GO:0006623 3 0.047
germ line stem cell division GO:0042078 2 0.047
negative regulation of t cell activation GO:0050868 65 0.046
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.046
regulation of ketone biosynthetic process GO:0010566 2 0.046
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.046
morphogenesis of a branching structure GO:0001763 203 0.046
bone development GO:0060348 120 0.046
olfactory lobe development GO:0021988 32 0.046
leukocyte apoptotic process GO:0071887 71 0.046
regulation of b cell activation GO:0050864 81 0.046
positive regulation of cell cycle GO:0045787 92 0.045
skin development GO:0043588 220 0.045
molting cycle GO:0042303 90 0.045
asymmetric neuroblast division GO:0055059 1 0.045
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.045
glycosyl compound metabolic process GO:1901657 246 0.044
mapk cascade GO:0000165 281 0.044
negative regulation of protein phosphorylation GO:0001933 126 0.044
regulation of protein transport GO:0051223 163 0.044
Fly
tissue remodeling GO:0048771 102 0.044
cellular divalent inorganic cation homeostasis GO:0072503 127 0.044
intracellular protein transport GO:0006886 204 0.044
Fly
negative regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000160 1 0.043
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.043
sensory organ morphogenesis GO:0090596 242 0.043
Fly
negative regulation of phosphorus metabolic process GO:0010563 184 0.043
mesoderm morphogenesis GO:0048332 64 0.043
ribonucleoside metabolic process GO:0009119 245 0.043
receptor mediated endocytosis of low density lipoprotein particle involved in cholesterol transport GO:0090118 1 0.043
positive regulation of cell motility GO:2000147 116 0.043
small molecule biosynthetic process GO:0044283 132 0.043
lymphocyte migration GO:0072676 26 0.042
positive regulation of cell activation GO:0050867 158 0.042
mesonephric epithelium development GO:0072163 94 0.042
regulation of cytoskeleton organization GO:0051493 122 0.042
Worm
ribonucleotide catabolic process GO:0009261 208 0.042
cardiac muscle tissue development GO:0048738 130 0.042
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity GO:0031585 2 0.042
divalent inorganic cation transport GO:0072511 178 0.041
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.041
nitrogen compound transport GO:0071705 271 0.041
Fly
fat cell differentiation GO:0045444 160 0.041
cation transmembrane transport GO:0098655 266 0.041
positive regulation of bmp signaling pathway GO:0030513 23 0.041
positive regulation of cytokine production GO:0001819 174 0.041
heart contraction GO:0060047 93 0.041
regulation of leukocyte apoptotic process GO:2000106 56 0.041
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.041
regulation of epithelial cell proliferation GO:0050678 141 0.040
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000164 1 0.040
cell fate commitment GO:0045165 210 0.040
Worm
immunoglobulin production GO:0002377 73 0.040
regulation of mapk cascade GO:0043408 248 0.040
response to molecule of bacterial origin GO:0002237 143 0.040
regulation of membrane potential GO:0042391 192 0.040
neural tube closure GO:0001843 90 0.040
inner ear morphogenesis GO:0042472 101 0.040
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.040
negative regulation of immune system process GO:0002683 209 0.039
intracellular sterol transport GO:0032366 3 0.039
nucleoside metabolic process GO:0009116 246 0.039
purine nucleotide metabolic process GO:0006163 302 0.039
regulation of cell substrate adhesion GO:0010810 73 0.039
myelination GO:0042552 74 0.038
negative regulation of planar cell polarity pathway involved in neural tube closure GO:2000168 1 0.038
appendage morphogenesis GO:0035107 149 0.038
Fly
cell division GO:0051301 120 0.038
synapse organization GO:0050808 125 0.038
negative regulation of protein metabolic process GO:0051248 282 0.038
muscle cell differentiation GO:0042692 261 0.038
limb development GO:0060173 166 0.037
muscle tissue development GO:0060537 308 0.037
nuclear import GO:0051170 95 0.037
defense response to other organism GO:0098542 197 0.037
stress activated protein kinase signaling cascade GO:0031098 81 0.037
regulation of cell cycle phase transition GO:1901987 77 0.037
protein localization to plasma membrane GO:0072659 57 0.037
cellular protein catabolic process GO:0044257 155 0.037
innate immune response GO:0045087 157 0.037
regulation of protein catabolic process GO:0042176 108 0.037
chondrocyte differentiation GO:0002062 72 0.036
muscle fiber development GO:0048747 76 0.036
response to cholesterol GO:0070723 4 0.036
negative regulation of transferase activity GO:0051348 85 0.036
cytoplasmic transport GO:0016482 234 0.036
spermatogenesis GO:0007283 284 0.036
renal inner medulla development GO:0072053 3 0.036
b cell activation GO:0042113 161 0.036
establishment of endothelial blood brain barrier GO:0014045 3 0.036
purine containing compound catabolic process GO:0072523 213 0.036
adaptive immune response GO:0002250 155 0.036
negative regulation of leukocyte proliferation GO:0070664 46 0.035
kidney morphogenesis GO:0060993 83 0.035
positive regulation of innate immune response GO:0045089 80 0.035
regulation of lymphocyte differentiation GO:0045619 107 0.035
negative regulation of phosphate metabolic process GO:0045936 184 0.035
negative regulation of ossification GO:0030279 49 0.035
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.035
ossification GO:0001503 216 0.035
myeloid leukocyte activation GO:0002274 83 0.035
nephron development GO:0072006 109 0.034
regulation of mitotic cell cycle phase transition GO:1901990 73 0.034
regulation of wnt signaling pathway GO:0030111 123 0.034
Fly
cellular ion homeostasis GO:0006873 165 0.034
developmental cell growth GO:0048588 84 0.034
cation homeostasis GO:0055080 212 0.034
neuron death GO:0070997 154 0.034
cell activation involved in immune response GO:0002263 126 0.034
gonad development GO:0008406 141 0.034
regulation of cell migration GO:0030334 219 0.034
Worm
defense response to virus GO:0051607 68 0.034
ion transmembrane transport GO:0034220 361 0.034
positive regulation of mitotic cell cycle GO:0045931 41 0.033
regulation of protein processing GO:0070613 96 0.033
leukocyte chemotaxis GO:0030595 69 0.033
metanephric loop of henle development GO:0072236 4 0.033
retinal ganglion cell axon guidance GO:0031290 18 0.033
purine nucleoside catabolic process GO:0006152 205 0.033
lymphocyte proliferation GO:0046651 164 0.033
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.033
embryonic limb morphogenesis GO:0030326 126 0.033
bone remodeling GO:0046849 53 0.033
negative regulation of protein processing GO:0010955 79 0.033
negative regulation of cell activation GO:0050866 111 0.033
cellular metal ion homeostasis GO:0006875 151 0.033
tube closure GO:0060606 91 0.032
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.032
cerebral cortex radially oriented cell migration GO:0021799 31 0.032
lymphocyte mediated immunity GO:0002449 139 0.032
attachment of spindle microtubules to kinetochore GO:0008608 4 0.032
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.032
embryonic skeletal system development GO:0048706 120 0.032
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.032
production of molecular mediator of immune response GO:0002440 103 0.032
retina morphogenesis in camera type eye GO:0060042 45 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
cellular response to lipid GO:0071396 145 0.031
protein localization to vacuole GO:0072665 4 0.031
regulation of purine nucleotide metabolic process GO:1900542 169 0.031
negative regulation of cytokine production GO:0001818 84 0.031
negative regulation of bmp signaling pathway GO:0030514 35 0.031
regulation of cytokine production GO:0001817 266 0.031
carboxylic acid transport GO:0046942 100 0.031
regulation of map kinase activity GO:0043405 120 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
purine containing compound metabolic process GO:0072521 311 0.031
defecation GO:0030421 1 0.031
dna replication GO:0006260 52 0.031
nephron morphogenesis GO:0072028 69 0.031
carbohydrate derivative catabolic process GO:1901136 231 0.030
positive regulation of secretion by cell GO:1903532 114 0.030
Fly
circulatory system process GO:0003013 197 0.030
regulation of fat cell differentiation GO:0045598 81 0.030
cell proliferation in hindbrain GO:0021534 10 0.030
nephron tubule morphogenesis GO:0072078 68 0.030
peptide hormone secretion GO:0030072 109 0.030
embryonic skeletal system morphogenesis GO:0048704 91 0.030
negative regulation of lymphocyte proliferation GO:0050672 45 0.030
anatomical structure homeostasis GO:0060249 145 0.030
glial cell differentiation GO:0010001 131 0.030
regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000159 1 0.030
stem cell proliferation GO:0072089 117 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.029
organ regeneration GO:0031100 2 0.029
regionalization GO:0003002 337 0.029
mammary gland epithelium development GO:0061180 65 0.029
monocarboxylic acid metabolic process GO:0032787 191 0.029
cardiocyte differentiation GO:0035051 87 0.029
cellular response to carbohydrate stimulus GO:0071322 50 0.029
cellular lipid metabolic process GO:0044255 323 0.029
adult locomotory behavior GO:0008344 91 0.029
negative regulation of immune effector process GO:0002698 55 0.029
exocytosis GO:0006887 121 0.029
locomotory behavior GO:0007626 195 0.029
lateral mesoderm formation GO:0048370 3 0.029
cellular calcium ion homeostasis GO:0006874 119 0.029
positive regulation of nucleotide catabolic process GO:0030813 88 0.029
salivary gland development GO:0007431 37 0.028
positive regulation of secretion GO:0051047 130 0.028
Fly
regulation of organelle organization GO:0033043 289 0.028
Worm
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.028
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.028
metal ion homeostasis GO:0055065 189 0.028
hormone secretion GO:0046879 128 0.028
interleukin 8 production GO:0032637 4 0.028
positive regulation of nucleoside metabolic process GO:0045979 91 0.028
membrane invagination GO:0010324 17 0.028
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 9 0.028
regulation of cell projection organization GO:0031344 206 0.028
aromatic compound catabolic process GO:0019439 286 0.028
positive regulation of binding GO:0051099 49 0.028
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.028
inner ear receptor cell differentiation GO:0060113 61 0.028
hindbrain morphogenesis GO:0021575 46 0.028
negative regulation of osteoblast differentiation GO:0045668 30 0.028

Wls disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.125
nervous system disease DOID:863 0 0.125
gastrointestinal system cancer DOID:3119 0 0.086
cancer DOID:162 0 0.086
disease of cellular proliferation DOID:14566 0 0.086
organ system cancer DOID:0050686 0 0.086
sensory system disease DOID:0050155 0 0.072
eye and adnexa disease DOID:1492 0 0.072
eye disease DOID:5614 0 0.072
central nervous system disease DOID:331 0 0.039
disease of metabolism DOID:0014667 0 0.035
neurodegenerative disease DOID:1289 0 0.028