Mus musculus

0 known processes

Tshb

thyroid stimulating hormone, beta subunit

(Aliases: MGC151208,MGC151206)

Tshb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.222
defense response to other organism GO:0098542 197 0.220
cytokine production GO:0001816 319 0.197
defense response to bacterium GO:0042742 119 0.153
regulation of interleukin 13 secretion GO:2000665 2 0.135
t helper 2 cell cytokine production GO:0035745 4 0.118
cellular amino acid metabolic process GO:0006520 103 0.118
g protein coupled receptor signaling pathway GO:0007186 243 0.117
cell cell recognition GO:0009988 44 0.101
immune effector process GO:0002252 321 0.099
leukocyte activation involved in immune response GO:0002366 126 0.099
negative regulation of interleukin 5 production GO:0032714 4 0.095
cell recognition GO:0008037 83 0.093
developmental maturation GO:0021700 193 0.091
regulation of leukocyte mediated immunity GO:0002703 104 0.088
fertilization GO:0009566 127 0.084
b cell activation GO:0042113 161 0.081
cell activation involved in immune response GO:0002263 126 0.079
cytokine secretion GO:0050663 72 0.078
regulation of cytokine production GO:0001817 266 0.078
regulation of protein transport GO:0051223 163 0.075
positive regulation of secretion GO:0051047 130 0.074
extracellular structure organization GO:0043062 148 0.070
adaptive immune response GO:0002250 155 0.068
macromolecule catabolic process GO:0009057 281 0.065
t cell activation GO:0042110 289 0.065
regulation of vesicle mediated transport GO:0060627 139 0.064
regulation of protein localization GO:0032880 231 0.063
regulation of secretion GO:0051046 274 0.063
protein secretion GO:0009306 111 0.062
negative regulation of cellular component organization GO:0051129 194 0.062
interleukin 5 secretion GO:0072603 2 0.061
inflammatory response GO:0006954 244 0.059
regulation of secretion by cell GO:1903530 249 0.059
negative regulation of immune system process GO:0002683 209 0.057
organonitrogen compound biosynthetic process GO:1901566 192 0.057
regulation of cell migration GO:0030334 219 0.056
single fertilization GO:0007338 82 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.056
lymphocyte activation involved in immune response GO:0002285 93 0.055
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.055
cellular ketone metabolic process GO:0042180 84 0.053
negative regulation of lymphocyte activation GO:0051250 91 0.052
negative regulation of t cell cytokine production GO:0002725 1 0.051
carbohydrate derivative biosynthetic process GO:1901137 183 0.051
peptidyl tyrosine modification GO:0018212 145 0.050
regulation of cell cycle GO:0051726 281 0.050
cytoplasmic transport GO:0016482 234 0.049
jak stat cascade GO:0007259 42 0.048
cellular response to lipopolysaccharide GO:0071222 77 0.046
negative regulation of cell proliferation GO:0008285 296 0.046
nucleotide metabolic process GO:0009117 332 0.045
positive regulation of innate immune response GO:0045089 80 0.045
leukocyte differentiation GO:0002521 342 0.045
lymphocyte mediated immunity GO:0002449 139 0.045
negative regulation of immune effector process GO:0002698 55 0.044
regulation of interleukin 5 secretion GO:2000662 2 0.043
positive regulation of defense response GO:0031349 124 0.043
divalent inorganic cation transport GO:0072511 178 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.042
regulation of lymphocyte mediated immunity GO:0002706 84 0.041
extracellular matrix organization GO:0030198 147 0.041
leukocyte chemotaxis GO:0030595 69 0.041
amine metabolic process GO:0009308 45 0.040
regulation of establishment of protein localization GO:0070201 181 0.040
sequestering of calcium ion GO:0051208 18 0.039
natural killer cell activation involved in immune response GO:0002323 10 0.038
protein catabolic process GO:0030163 221 0.038
male gamete generation GO:0048232 285 0.038
carboxylic acid transport GO:0046942 100 0.038
myeloid leukocyte migration GO:0097529 57 0.038
lymphocyte proliferation GO:0046651 164 0.037
negative regulation of interleukin 5 secretion GO:2000663 1 0.037
leukocyte mediated immunity GO:0002443 174 0.037
regulation of nucleotide metabolic process GO:0006140 169 0.037
regulation of cell motility GO:2000145 236 0.037
ubiquitin dependent protein catabolic process GO:0006511 129 0.036
germ cell development GO:0007281 185 0.036
negative regulation of protein modification process GO:0031400 163 0.036
regulation of lymphocyte activation GO:0051249 240 0.035
b cell mediated immunity GO:0019724 71 0.035
regulation of defense response GO:0031347 233 0.035
binding of sperm to zona pellucida GO:0007339 34 0.034
negative regulation of interleukin 13 production GO:0032696 2 0.034
cellular amine metabolic process GO:0044106 44 0.034
interleukin 13 secretion GO:0072611 2 0.033
negative regulation of molecular function GO:0044092 258 0.033
positive regulation of cell death GO:0010942 224 0.033
regulation of t cell activation GO:0050863 170 0.032
regulation of cell activation GO:0050865 289 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
protein maturation GO:0051604 176 0.032
acute inflammatory response GO:0002526 41 0.032
regulation of innate immune response GO:0045088 91 0.032
negative regulation of cellular amine metabolic process GO:0033239 1 0.032
ribose phosphate metabolic process GO:0019693 291 0.031
regulation of lymphocyte proliferation GO:0050670 117 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
response to transforming growth factor beta GO:0071559 88 0.031
negative regulation of protein metabolic process GO:0051248 282 0.031
positive regulation of keratinocyte proliferation GO:0010838 4 0.030
cellular lipid metabolic process GO:0044255 323 0.029
regulation of t helper 2 cell cytokine production GO:2000551 3 0.029
bone development GO:0060348 120 0.029
regulation of intracellular transport GO:0032386 159 0.029
response to lipopolysaccharide GO:0032496 128 0.029
regulation of jak stat cascade GO:0046425 34 0.028
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
immune response regulating signaling pathway GO:0002764 125 0.028
regulation of t cell differentiation GO:0045580 83 0.028
sensory perception GO:0007600 245 0.028
response to acid chemical GO:0001101 111 0.028
production of molecular mediator of immune response GO:0002440 103 0.028
membrane organization GO:0061024 245 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
intracellular protein transport GO:0006886 204 0.028
regulation of cytoplasmic transport GO:1903649 112 0.028
natural killer cell activation GO:0030101 44 0.027
activation of immune response GO:0002253 138 0.027
organelle localization GO:0051640 179 0.027
positive regulation of homeostatic process GO:0032846 64 0.027
divalent metal ion transport GO:0070838 172 0.027
rhodopsin mediated signaling pathway GO:0016056 4 0.027
regulation of endocytosis GO:0030100 69 0.027
oxidation reduction process GO:0055114 342 0.026
neutrophil migration GO:1990266 37 0.026
organophosphate catabolic process GO:0046434 232 0.026
cellular macromolecule catabolic process GO:0044265 206 0.026
nucleotide catabolic process GO:0009166 217 0.025
negative regulation of cell activation GO:0050866 111 0.025
cellular response to biotic stimulus GO:0071216 92 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
regulation of neuron projection development GO:0010975 169 0.025
transmembrane transport GO:0055085 412 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
peptidyl amino acid modification GO:0018193 336 0.024
second messenger mediated signaling GO:0019932 73 0.024
purine ribonucleotide metabolic process GO:0009150 290 0.024
organophosphate biosynthetic process GO:0090407 122 0.024
leukocyte proliferation GO:0070661 172 0.024
peptidyl tyrosine phosphorylation GO:0018108 143 0.024
spermatogenesis GO:0007283 284 0.024
amino acid transmembrane transport GO:0003333 37 0.024
negative regulation of interleukin 13 secretion GO:2000666 1 0.024
regulation of protein secretion GO:0050708 82 0.024
myeloid leukocyte activation GO:0002274 83 0.023
regulation of transmembrane transport GO:0034762 128 0.023
sperm egg recognition GO:0035036 37 0.023
b cell differentiation GO:0030183 78 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
negative regulation of multi organism process GO:0043901 68 0.023
l amino acid transport GO:0015807 32 0.023
purine containing compound metabolic process GO:0072521 311 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.022
regulation of inflammatory response GO:0050727 147 0.022
regulation of neural retina development GO:0061074 3 0.022
negative regulation of leukocyte mediated immunity GO:0002704 29 0.022
response to molecule of bacterial origin GO:0002237 143 0.022
cellular response to lipid GO:0071396 145 0.022
cardiac chamber morphogenesis GO:0003206 93 0.022
endomembrane system organization GO:0010256 147 0.021
lymphocyte differentiation GO:0030098 242 0.021
defense response to gram positive bacterium GO:0050830 50 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
phagocytosis GO:0006909 66 0.021
regulation of exocytosis GO:0017157 61 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
neuron death GO:0070997 154 0.020
mitochondrion distribution GO:0048311 4 0.020
response to organonitrogen compound GO:0010243 246 0.020
negative regulation of cytokine production GO:0001818 84 0.020
defense response to virus GO:0051607 68 0.020
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.020
endochondral bone morphogenesis GO:0060350 50 0.020
spermatid development GO:0007286 108 0.020
regulation of membrane potential GO:0042391 192 0.020
positive regulation of secretion by cell GO:1903532 114 0.019
negative regulation of t cell activation GO:0050868 65 0.019
gland development GO:0048732 330 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
chemotaxis GO:0006935 247 0.019
t cell proliferation GO:0042098 120 0.019
mitochondrion organization GO:0007005 134 0.018
cell maturation GO:0048469 127 0.018
cytokine mediated signaling pathway GO:0019221 115 0.018
regulation of ion transmembrane transport GO:0034765 119 0.018
multicellular organism growth GO:0035264 161 0.018
blood circulation GO:0008015 195 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
innate immune response GO:0045087 157 0.018
cellular response to molecule of bacterial origin GO:0071219 83 0.018
plasma membrane organization GO:0007009 90 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
homeostasis of number of cells GO:0048872 210 0.018
spermatid differentiation GO:0048515 115 0.018
nuclear division GO:0000280 158 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
myeloid cell differentiation GO:0030099 233 0.018
oogenesis GO:0048477 56 0.017
regulation of homeostatic process GO:0032844 182 0.017
striated muscle tissue development GO:0014706 293 0.017
purine containing compound biosynthetic process GO:0072522 70 0.017
leukocyte mediated cytotoxicity GO:0001909 62 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
circulatory system process GO:0003013 197 0.017
regulation of organelle organization GO:0033043 289 0.017
phospholipid metabolic process GO:0006644 87 0.017
regulation of myeloid leukocyte differentiation GO:0002761 58 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
regulation of cell cycle process GO:0010564 160 0.017
stem cell development GO:0048864 219 0.017
cation transport GO:0006812 399 0.017
protein ubiquitination GO:0016567 171 0.017
interspecies interaction between organisms GO:0044419 83 0.016
regulation of chemokine secretion GO:0090196 4 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
cellular protein catabolic process GO:0044257 155 0.016
mitral valve development GO:0003174 4 0.016
cellular response to acid chemical GO:0071229 68 0.016
immunoglobulin mediated immune response GO:0016064 69 0.016
positive regulation of cell cycle process GO:0090068 61 0.016
cation transmembrane transport GO:0098655 266 0.016
purine nucleotide biosynthetic process GO:0006164 65 0.016
granulocyte migration GO:0097530 43 0.016
protein processing GO:0016485 163 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
regulation of adaptive immune response GO:0002819 90 0.015
ribonucleotide biosynthetic process GO:0009260 59 0.015
regulation of ossification GO:0030278 112 0.015
regulation of nuclear division GO:0051783 56 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
myelination GO:0042552 74 0.015
ion transmembrane transport GO:0034220 361 0.015
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.015
nitrogen compound transport GO:0071705 271 0.015
neutrophil chemotaxis GO:0030593 36 0.015
connective tissue development GO:0061448 179 0.015
humoral immune response GO:0006959 57 0.015
regulation of type 2 immune response GO:0002828 18 0.015
regulation of neuron death GO:1901214 134 0.015
positive regulation of cytokine production GO:0001819 174 0.015
axonogenesis GO:0007409 274 0.015
t cell differentiation GO:0030217 174 0.015
covalent chromatin modification GO:0016569 163 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
dna metabolic process GO:0006259 303 0.015
calcium ion dependent exocytosis GO:0017156 35 0.015
organic anion transport GO:0015711 137 0.015
granulocyte chemotaxis GO:0071621 39 0.015
negative regulation of cell development GO:0010721 169 0.014
positive regulation of camp mediated signaling GO:0043950 3 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.014
anatomical structure homeostasis GO:0060249 145 0.014
muscle tissue development GO:0060537 308 0.014
osteoclast differentiation GO:0030316 62 0.014
cytokine biosynthetic process GO:0042089 68 0.014
endocytosis GO:0006897 168 0.014
cardiac ventricle development GO:0003231 83 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
regulation of cytokine secretion GO:0050707 61 0.014
calcium mediated signaling GO:0019722 46 0.014
response to insulin GO:0032868 100 0.014
keratinocyte proliferation GO:0043616 21 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
forebrain development GO:0030900 302 0.014
regulation of cell projection organization GO:0031344 206 0.014
odontogenesis of dentin containing tooth GO:0042475 66 0.014
nuclear transport GO:0051169 139 0.014
protein targeting GO:0006605 143 0.014
organic acid biosynthetic process GO:0016053 86 0.014
negative regulation of cell cycle GO:0045786 123 0.014
regulation of myeloid cell differentiation GO:0045637 96 0.013
tissue homeostasis GO:0001894 115 0.013
anion transport GO:0006820 177 0.013
neuron apoptotic process GO:0051402 142 0.013
somatotropin secreting cell differentiation GO:0060126 4 0.013
regulation of binding GO:0051098 111 0.013
multicellular organismal metabolic process GO:0044236 28 0.013
regulation of muscle tissue development GO:1901861 97 0.013
negative regulation of adaptive immune response GO:0002820 25 0.013
calcium ion transport GO:0006816 159 0.013
skeletal muscle organ development GO:0060538 163 0.013
skeletal muscle cell differentiation GO:0035914 66 0.013
positive regulation of t cell activation GO:0050870 101 0.013
negative regulation of leukocyte proliferation GO:0070664 46 0.013
positive regulation of cell motility GO:2000147 116 0.013
negative regulation of protein transport GO:0051224 46 0.013
organic acid transport GO:0015849 101 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
cellular modified amino acid metabolic process GO:0006575 63 0.013
heart process GO:0003015 94 0.013
locomotory behavior GO:0007626 195 0.013
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.013
mrna metabolic process GO:0016071 84 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
negative regulation of lymphocyte proliferation GO:0050672 45 0.012
heart morphogenesis GO:0003007 178 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
ribose phosphate biosynthetic process GO:0046390 59 0.012
proton transport GO:0015992 35 0.012
neural tube formation GO:0001841 108 0.012
type 2 immune response GO:0042092 23 0.012
cardiac muscle contraction GO:0060048 32 0.012
appendage development GO:0048736 166 0.012
response to growth factor GO:0070848 198 0.012
response to inorganic substance GO:0010035 96 0.012
Rat
methylation GO:0032259 134 0.012
metencephalon development GO:0022037 89 0.012
axon ensheathment GO:0008366 76 0.012
endocrine system development GO:0035270 98 0.012
positive regulation of nuclear division GO:0051785 27 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
regulation of protein maturation GO:1903317 96 0.012
multicellular organismal signaling GO:0035637 91 0.012
negative regulation of growth GO:0045926 99 0.011
angiogenesis GO:0001525 201 0.011
exocytosis GO:0006887 121 0.011
rna processing GO:0006396 105 0.011
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.011
positive regulation of cell cycle GO:0045787 92 0.011
response to peptide hormone GO:0043434 127 0.011
immune response activating signal transduction GO:0002757 116 0.011
regulation of protein catabolic process GO:0042176 108 0.011
aromatic compound catabolic process GO:0019439 286 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
leukocyte migration GO:0050900 124 0.011
heart contraction GO:0060047 93 0.011
regulation of keratinocyte proliferation GO:0010837 15 0.011
regulation of t cell proliferation GO:0042129 92 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
negative regulation of neuron death GO:1901215 98 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
multi multicellular organism process GO:0044706 109 0.011
striated muscle contraction GO:0006941 45 0.011
regulation of multi organism process GO:0043900 111 0.011
regulation of exit from mitosis GO:0007096 1 0.011
carbohydrate metabolic process GO:0005975 230 0.011
epidermis development GO:0008544 187 0.011
pancreatic pp cell fate commitment GO:0003329 2 0.011
cell growth GO:0016049 130 0.011
transmission of nerve impulse GO:0019226 76 0.011
development of primary sexual characteristics GO:0045137 143 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
regulation of neuron differentiation GO:0045664 281 0.011
gonad development GO:0008406 141 0.011
skin development GO:0043588 220 0.010
viral entry into host cell GO:0046718 15 0.010
organelle fission GO:0048285 170 0.010
cell adhesion GO:0007155 329 0.010
response to extracellular stimulus GO:0009991 127 0.010
Rat
sclerotome development GO:0061056 4 0.010
cell substrate adhesion GO:0031589 130 0.010
cerebellum development GO:0021549 77 0.010
regulation of renal sodium excretion GO:0035813 3 0.010
t cell mediated immunity GO:0002456 50 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.010
developmental cell growth GO:0048588 84 0.010
glycosyl compound metabolic process GO:1901657 246 0.010
collagen metabolic process GO:0032963 17 0.010
cellular response to oxidative stress GO:0034599 76 0.010
receptor mediated endocytosis GO:0006898 51 0.010
ribonucleoside metabolic process GO:0009119 245 0.010
ossification GO:0001503 216 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
antibacterial peptide biosynthetic process GO:0002780 2 0.010
mesodermal cell migration GO:0008078 4 0.010

Tshb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.014
disease of anatomical entity DOID:7 0 0.014
Human
eye and adnexa disease DOID:1492 0 0.014
nervous system disease DOID:863 0 0.014
retinal disease DOID:5679 0 0.014
retinal degeneration DOID:8466 0 0.014
retinitis pigmentosa DOID:10584 0 0.014
eye disease DOID:5614 0 0.014