Mus musculus

173 known processes

Epas1

endothelial PAS domain protein 1

(Aliases: HIF2A,MOP2,bHLHe73,HLF,HIF-2alpha,HRF)

Epas1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.977
Mouse
blood vessel morphogenesis GO:0048514 285 0.958
4 hydroxyproline metabolic process GO:0019471 5 0.948
heart trabecula formation GO:0060347 14 0.947
respiratory system development GO:0060541 190 0.930
angiogenesis GO:0001525 201 0.899
regulation of neuron apoptotic process GO:0043523 122 0.874
Zebrafish Mouse
muscle tissue development GO:0060537 308 0.869
positive regulation of protein modification process GO:0031401 299 0.844
mapk cascade GO:0000165 281 0.844
peptidyl proline hydroxylation to 4 hydroxy l proline GO:0018401 2 0.832
cardiac muscle tissue development GO:0048738 130 0.818
cell type specific apoptotic process GO:0097285 268 0.807
Zebrafish Mouse
cellular response to growth factor stimulus GO:0071363 197 0.774
Mouse
regulation of muscle system process GO:0090257 80 0.773
homeostasis of number of cells GO:0048872 210 0.768
regulation of protein kinase activity GO:0045859 232 0.744
cellular amino acid metabolic process GO:0006520 103 0.738
negative regulation of cell proliferation GO:0008285 296 0.733
lung development GO:0030324 164 0.721
cell growth GO:0016049 130 0.694
Fly
gland development GO:0048732 330 0.675
Mouse
physiological cardiac muscle hypertrophy GO:0003301 3 0.669
blood circulation GO:0008015 195 0.667
erythrocyte differentiation GO:0030218 88 0.666
glycosyl compound catabolic process GO:1901658 206 0.654
hormone secretion GO:0046879 128 0.650
Mouse
alpha amino acid metabolic process GO:1901605 59 0.649
regulation of hydrolase activity GO:0051336 246 0.639
myeloid cell differentiation GO:0030099 233 0.634
regulation of cellular amine metabolic process GO:0033238 20 0.634
regulation of myeloid cell differentiation GO:0045637 96 0.629
Mouse
peptidyl amino acid modification GO:0018193 336 0.628
negative regulation of neuron death GO:1901215 98 0.628
Mouse
striated muscle tissue development GO:0014706 293 0.627
regulation of homeostatic process GO:0032844 182 0.624
Mouse
regulation of kinase activity GO:0043549 249 0.622
regulation of mapk cascade GO:0043408 248 0.619
regulation of protein serine threonine kinase activity GO:0071900 157 0.618
regulation of anatomical structure size GO:0090066 178 0.618
organophosphate catabolic process GO:0046434 232 0.614
embryonic placenta development GO:0001892 98 0.591
response to decreased oxygen levels GO:0036293 59 0.590
myeloid cell homeostasis GO:0002262 114 0.588
neuron apoptotic process GO:0051402 142 0.585
Zebrafish Mouse
regulation of heart contraction GO:0008016 77 0.579
response to hypoxia GO:0001666 58 0.572
circulatory system process GO:0003013 197 0.569
regulation of cell activation GO:0050865 289 0.567
nuclear transport GO:0051169 139 0.556
positive regulation of nervous system development GO:0051962 221 0.546
Mouse
muscle cell differentiation GO:0042692 261 0.540
organonitrogen compound catabolic process GO:1901565 264 0.537
regulation of angiogenesis GO:0045765 81 0.533
purine nucleotide metabolic process GO:0006163 302 0.532
stem cell differentiation GO:0048863 268 0.522
Mouse
response to inactivity GO:0014854 4 0.519
peptidyl proline hydroxylation GO:0019511 3 0.518
bmp signaling pathway GO:0030509 93 0.512
response to peptide GO:1901652 136 0.512
Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.504
regulation of cell adhesion GO:0030155 154 0.501
heart process GO:0003015 94 0.499
purine containing compound metabolic process GO:0072521 311 0.496
embryonic organ morphogenesis GO:0048562 276 0.496
Mouse
oxygen homeostasis GO:0032364 2 0.494
Mouse
regulation of bmp signaling pathway GO:0030510 60 0.493
kidney development GO:0001822 213 0.489
Mouse
cellular homeostasis GO:0019725 240 0.487
Mouse
ameboidal type cell migration GO:0001667 128 0.486
Mouse
metal ion homeostasis GO:0055065 189 0.480
t cell activation GO:0042110 289 0.479
ion transmembrane transport GO:0034220 361 0.476
regulation of cell size GO:0008361 72 0.475
epithelial cell migration GO:0010631 63 0.472
Mouse
regulation of ossification GO:0030278 112 0.463
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.463
skeletal system development GO:0001501 356 0.458
Mouse
vascular process in circulatory system GO:0003018 62 0.456
nitrogen compound transport GO:0071705 271 0.453
Mouse
digestive tract morphogenesis GO:0048546 147 0.453
Mouse
connective tissue development GO:0061448 179 0.453
Mouse
oxidation reduction process GO:0055114 342 0.452
fat cell differentiation GO:0045444 160 0.448
negative regulation of neuron apoptotic process GO:0043524 92 0.443
Mouse
regulation of cell migration GO:0030334 219 0.436
Mouse Fly
learning or memory GO:0007611 148 0.431
Mouse
urogenital system development GO:0001655 261 0.430
Mouse
regulation of cell growth GO:0001558 91 0.427
Fly
cell growth involved in cardiac muscle cell development GO:0061049 3 0.425
regulation of response to wounding GO:1903034 189 0.418
ribonucleoside triphosphate metabolic process GO:0009199 220 0.414
regulation of nucleotide metabolic process GO:0006140 169 0.412
heart contraction GO:0060047 93 0.404
muscle adaptation GO:0043500 39 0.403
cation transport GO:0006812 399 0.403
monocarboxylic acid metabolic process GO:0032787 191 0.394
Mouse
t cell differentiation GO:0030217 174 0.394
peptide hormone secretion GO:0030072 109 0.393
Mouse
response to insulin GO:0032868 100 0.391
Fly
cellular modified amino acid metabolic process GO:0006575 63 0.389
cellular response to organonitrogen compound GO:0071417 145 0.382
Fly
regulation of vasculature development GO:1901342 88 0.380
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.373
Mouse
positive regulation of mapk cascade GO:0043410 170 0.368
regulation of neuron death GO:1901214 134 0.364
Zebrafish Mouse
positive regulation of growth GO:0045927 104 0.364
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.363
metanephric glomerular mesangium development GO:0072223 3 0.363
inorganic cation transmembrane transport GO:0098662 207 0.359
regulation of erythrocyte differentiation GO:0045646 23 0.357
Mouse
trachea development GO:0060438 18 0.357
Fly
protein export from nucleus GO:0006611 20 0.356
wound healing GO:0042060 157 0.350
Mouse
embryonic heart tube development GO:0035050 65 0.350
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.345
inflammatory response GO:0006954 244 0.344
Mouse
regulation of hormone levels GO:0010817 211 0.343
Mouse
cell adhesion GO:0007155 329 0.338
epithelial tube morphogenesis GO:0060562 303 0.334
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.331
digestive tract development GO:0048565 190 0.328
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.326
nucleoside phosphate metabolic process GO:0006753 338 0.324
regulation of transferase activity GO:0051338 263 0.322
positive regulation of kinase activity GO:0033674 155 0.321
nucleocytoplasmic transport GO:0006913 139 0.320
aromatic compound catabolic process GO:0019439 286 0.320
cytoplasmic transport GO:0016482 234 0.319
regulation of hippo signaling GO:0035330 1 0.315
cardiac chamber morphogenesis GO:0003206 93 0.310
Mouse
glucocorticoid biosynthetic process GO:0006704 5 0.308
positive regulation of behavior GO:0048520 40 0.306
cytokine production GO:0001816 319 0.304
regulation of receptor activity GO:0010469 41 0.304
response to organic cyclic compound GO:0014070 198 0.303
regulation of muscle contraction GO:0006937 49 0.298
epithelium migration GO:0090132 63 0.297
Mouse
ribose phosphate metabolic process GO:0019693 291 0.296
neuron death GO:0070997 154 0.296
Zebrafish Mouse
positive regulation of cell motility GO:2000147 116 0.295
Mouse
developmental cell growth GO:0048588 84 0.294
leukocyte differentiation GO:0002521 342 0.284
regulation of system process GO:0044057 200 0.284
blood vessel remodeling GO:0001974 33 0.284
positive regulation of transferase activity GO:0051347 167 0.282
regulation of t cell activation GO:0050863 170 0.279
positive regulation of protein kinase activity GO:0045860 144 0.278
alcohol metabolic process GO:0006066 116 0.275
regulation of blood circulation GO:1903522 93 0.274
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.273
intracellular protein transport GO:0006886 204 0.272
labyrinthine layer development GO:0060711 49 0.270
heart trabecula morphogenesis GO:0061384 26 0.270
regulation of cellular ketone metabolic process GO:0010565 66 0.268
muscle hypertrophy GO:0014896 24 0.268
camera type eye development GO:0043010 266 0.265
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.263
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.263
ribonucleotide metabolic process GO:0009259 291 0.262
regulation of map kinase activity GO:0043405 120 0.261
cellular response to insulin stimulus GO:0032869 78 0.261
Fly
cardiac septum development GO:0003279 59 0.260
sensory perception of mechanical stimulus GO:0050954 107 0.258
regulation of lymphocyte differentiation GO:0045619 107 0.258
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.254
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.252
regulation of neural precursor cell proliferation GO:2000177 70 0.252
Mouse
epidermis development GO:0008544 187 0.251
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 14 0.250
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.250
chemotaxis GO:0006935 247 0.250
ribonucleoside metabolic process GO:0009119 245 0.248
regulation of epithelial cell migration GO:0010632 35 0.248
Mouse
response to transforming growth factor beta GO:0071559 88 0.246
development of primary sexual characteristics GO:0045137 143 0.245
nucleotide catabolic process GO:0009166 217 0.240
branching morphogenesis of an epithelial tube GO:0048754 159 0.240
regulation of leukocyte differentiation GO:1902105 159 0.239
bone development GO:0060348 120 0.235
lymphocyte differentiation GO:0030098 242 0.235
respiratory tube development GO:0030323 167 0.234
regulation of mesenchymal cell proliferation GO:0010464 37 0.233
morphogenesis of embryonic epithelium GO:0016331 159 0.233
Mouse
calcium ion transport GO:0006816 159 0.233
ventricular septum development GO:0003281 42 0.230
regulation of cellular component size GO:0032535 121 0.228
stem cell development GO:0048864 219 0.228
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.227
trunk neural crest cell migration GO:0036484 4 0.224
trabecula formation GO:0060343 24 0.224
cell junction assembly GO:0034329 52 0.224
male sex differentiation GO:0046661 109 0.220
renal system process involved in regulation of blood volume GO:0001977 4 0.220
g protein coupled receptor signaling pathway GO:0007186 243 0.220
purine containing compound catabolic process GO:0072523 213 0.219
positive regulation of cell growth GO:0030307 33 0.218
regulation of cellular amino acid metabolic process GO:0006521 5 0.218
cardiac septum morphogenesis GO:0060411 46 0.217
cellular response to erythropoietin GO:0036018 1 0.217
trabecula morphogenesis GO:0061383 40 0.217
carbohydrate derivative catabolic process GO:1901136 231 0.216
negative regulation of phosphorus metabolic process GO:0010563 184 0.215
morphogenesis of a branching structure GO:0001763 203 0.214
positive regulation of chemotaxis GO:0050921 38 0.214
t cell differentiation in thymus GO:0033077 77 0.214
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.212
developmental growth involved in morphogenesis GO:0060560 138 0.212
regulation of ras gtpase activity GO:0032318 88 0.212
regulation of lymphocyte activation GO:0051249 240 0.211
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.211
peptide secretion GO:0002790 114 0.211
Mouse
regulation of endothelial cell migration GO:0010594 22 0.210
glucose homeostasis GO:0042593 128 0.210
Mouse
ossification GO:0001503 216 0.208
Mouse
erythropoietin mediated signaling pathway GO:0038162 1 0.208
regulation of transmembrane transport GO:0034762 128 0.208
regulation of cellular response to hypoxia GO:1900037 2 0.207
cardiac muscle contraction GO:0060048 32 0.207
multicellular organism growth GO:0035264 161 0.207
placenta development GO:0001890 140 0.205
response to radiation GO:0009314 165 0.203
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.203
response to corticosterone GO:0051412 1 0.200
blood coagulation GO:0007596 76 0.200
response to erythropoietin GO:0036017 1 0.199
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.199
regulation of membrane potential GO:0042391 192 0.199
cardiac muscle tissue morphogenesis GO:0055008 44 0.198
cardiac muscle cell contraction GO:0086003 7 0.196
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.196
positive regulation of epithelial cell migration GO:0010634 19 0.195
Mouse
bone mineralization GO:0030282 54 0.195
Mouse
lung alveolus development GO:0048286 45 0.193
regulation of epithelial cell proliferation GO:0050678 141 0.192
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.191
steroid metabolic process GO:0008202 119 0.191
cellular ketone metabolic process GO:0042180 84 0.189
response to inorganic substance GO:0010035 96 0.189
negative regulation of growth GO:0045926 99 0.188
Mouse Fly
vegf activated neuropilin signaling pathway GO:0038190 2 0.187
skeletal system morphogenesis GO:0048705 203 0.186
response to growth factor GO:0070848 198 0.186
Mouse
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.186
sympathetic neuron projection guidance GO:0097491 4 0.185
lipid biosynthetic process GO:0008610 179 0.184
memory GO:0007613 58 0.182
nuclear export GO:0051168 34 0.181
response to oxygen levels GO:0070482 62 0.179
cardiac chamber development GO:0003205 108 0.179
Mouse
telencephalon development GO:0021537 186 0.175
Mouse
positive regulation of cell migration GO:0030335 109 0.174
Mouse
hair follicle development GO:0001942 85 0.174
tissue migration GO:0090130 68 0.174
Mouse
positive regulation of cell development GO:0010720 237 0.174
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.171
cellular chemical homeostasis GO:0055082 215 0.167
Mouse
regulation of hormone secretion GO:0046883 88 0.166
Mouse
heterocycle catabolic process GO:0046700 280 0.166
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.165
extracellular matrix organization GO:0030198 147 0.164
ribonucleotide catabolic process GO:0009261 208 0.164
cytokine mediated signaling pathway GO:0019221 115 0.163
microtubule based process GO:0007017 236 0.163
skeletal muscle organ development GO:0060538 163 0.162
multi multicellular organism process GO:0044706 109 0.162
Mouse
regulation of ion transport GO:0043269 215 0.161
axon guidance GO:0007411 141 0.161
ventricular cardiac muscle cell action potential GO:0086005 4 0.161
hypoxia inducible factor 1alpha signaling pathway GO:0097411 2 0.160
Mouse
regulation of chemotaxis GO:0050920 53 0.160
positive regulation of angiogenesis GO:0045766 46 0.159
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.159
synaptic transmission GO:0007268 329 0.157
negative regulation of cell fate specification GO:0009996 4 0.157
response to peptide hormone GO:0043434 127 0.157
Fly
cardiac ventricle development GO:0003231 83 0.155
Mouse
positive regulation of leukocyte differentiation GO:1902107 86 0.155
regulation of ion transmembrane transport GO:0034765 119 0.155
heart morphogenesis GO:0003007 178 0.155
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.154
regulation of cellular response to growth factor stimulus GO:0090287 82 0.154
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.153
muscle contraction GO:0006936 101 0.152
myeloid leukocyte differentiation GO:0002573 119 0.152
cation homeostasis GO:0055080 212 0.152
neural fold elevation formation GO:0021502 1 0.152
Mouse
amine metabolic process GO:0009308 45 0.151
male gonad development GO:0008584 88 0.150
neural tube formation GO:0001841 108 0.150
Mouse
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.149
organ growth GO:0035265 117 0.149
nucleotide metabolic process GO:0009117 332 0.149
brown fat cell differentiation GO:0050873 36 0.148
neural crest cell migration GO:0001755 32 0.148
Mouse
positive regulation of cell activation GO:0050867 158 0.147
regulation of cell projection assembly GO:0060491 38 0.147
hippo signaling GO:0035329 11 0.146
negative regulation of phosphate metabolic process GO:0045936 184 0.145
positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 5 0.145
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.144
associative learning GO:0008306 61 0.142
Mouse
establishment of protein localization to organelle GO:0072594 118 0.142
lung morphogenesis GO:0060425 50 0.142
regulation of cardiac muscle contraction GO:0055117 21 0.142
glycerolipid metabolic process GO:0046486 122 0.142
leukocyte proliferation GO:0070661 172 0.140
forebrain generation of neurons GO:0021872 63 0.140
epithelial cell proliferation GO:0050673 174 0.140
regulation of cellular component biogenesis GO:0044087 181 0.139
negative regulation of hydrolase activity GO:0051346 71 0.139
regulation of striated muscle cell differentiation GO:0051153 81 0.139
positive regulation of apoptotic process GO:0043065 217 0.139
negative regulation of epithelial cell proliferation GO:0050680 64 0.139
positive regulation of nucleotide catabolic process GO:0030813 88 0.139
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.138
embryonic hemopoiesis GO:0035162 23 0.138
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.138
positive regulation of glial cell proliferation GO:0060252 4 0.138
coagulation GO:0050817 78 0.138
single organismal cell cell adhesion GO:0016337 131 0.137
regulation of reproductive process GO:2000241 66 0.137
regulation of cardiac cell fate specification GO:2000043 1 0.136
purine nucleoside metabolic process GO:0042278 241 0.136
spermatogenesis GO:0007283 284 0.135
regulation of cell projection organization GO:0031344 206 0.135
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.134
negative regulation of immune system process GO:0002683 209 0.133
tissue remodeling GO:0048771 102 0.133
purine ribonucleoside catabolic process GO:0046130 205 0.132
regulation of glutamate secretion GO:0014048 3 0.132
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.132
hemostasis GO:0007599 78 0.131
sensory perception of sound GO:0007605 97 0.131
leukocyte mediated immunity GO:0002443 174 0.131
regulation of wound healing GO:0061041 40 0.130
extracellular structure organization GO:0043062 148 0.130
regulation of cell motility GO:2000145 236 0.129
Mouse Fly
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.129
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.129
determination of left right symmetry GO:0007368 80 0.129
Mouse
inner ear morphogenesis GO:0042472 101 0.128
regulation of cell growth involved in cardiac muscle cell development GO:0061050 3 0.127
diencephalon development GO:0021536 63 0.127
trachea morphogenesis GO:0060439 8 0.127
negative regulation of protein phosphorylation GO:0001933 126 0.127
response to reactive oxygen species GO:0000302 56 0.127
developmental maturation GO:0021700 193 0.127
positive regulation of bmp signaling pathway GO:0030513 23 0.126
positive regulation of smooth muscle cell migration GO:0014911 4 0.126
muscle system process GO:0003012 141 0.126
cellular response to lipid GO:0071396 145 0.125
cellular response to monosaccharide stimulus GO:0071326 47 0.125
Mouse
sensory organ morphogenesis GO:0090596 242 0.125
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.125
response to oxidative stress GO:0006979 123 0.125
negative regulation of cell growth GO:0030308 44 0.124
Fly
molting cycle GO:0042303 90 0.124
gliogenesis GO:0042063 141 0.123
regulation of nucleoside metabolic process GO:0009118 130 0.123
purine nucleotide catabolic process GO:0006195 211 0.123
regulation of purine nucleotide catabolic process GO:0033121 122 0.122
positive regulation of lymphocyte activation GO:0051251 140 0.121
outflow tract morphogenesis GO:0003151 53 0.121
Mouse
axonogenesis GO:0007409 274 0.120
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.120
microtubule based movement GO:0007018 84 0.119
response to organonitrogen compound GO:0010243 246 0.118
Fly
tissue homeostasis GO:0001894 115 0.118
drug catabolic process GO:0042737 2 0.118
muscle tissue morphogenesis GO:0060415 53 0.118
response to mineralocorticoid GO:0051385 1 0.118
nucleoside triphosphate catabolic process GO:0009143 205 0.118
regulation of calcium ion transmembrane transport GO:1903169 20 0.118
apoptotic signaling pathway GO:0097190 306 0.117
nucleoside catabolic process GO:0009164 206 0.117
sensory perception GO:0007600 245 0.117
lymphocyte proliferation GO:0046651 164 0.117
appendage morphogenesis GO:0035107 149 0.117
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.116
fatty acid metabolic process GO:0006631 121 0.116
regulation of lipid metabolic process GO:0019216 118 0.115
cell maturation GO:0048469 127 0.114
regulation of blood pressure GO:0008217 93 0.114
amide transport GO:0042886 138 0.113
Mouse
gonad development GO:0008406 141 0.113
regulation of vesicle mediated transport GO:0060627 139 0.113
sympathetic neuron projection extension GO:0097490 4 0.113
ventral trunk neural crest cell migration GO:0036486 4 0.111
ribonucleotide biosynthetic process GO:0009260 59 0.111
osteoclast differentiation GO:0030316 62 0.110
embryonic epithelial tube formation GO:0001838 130 0.109
Mouse
facioacoustic ganglion development GO:1903375 3 0.109
positive regulation of ion transport GO:0043270 65 0.107
regulation of protein stability GO:0031647 52 0.107
regulation of tube size GO:0035150 57 0.107
regulation of cellular response to stress GO:0080135 159 0.107
negative regulation of cell development GO:0010721 169 0.107
negative regulation of nervous system development GO:0051961 156 0.107
biomineral tissue development GO:0031214 64 0.106
Mouse
embryonic skeletal system development GO:0048706 120 0.106
cellular response to cytokine stimulus GO:0071345 189 0.106
negative regulation of cellular component organization GO:0051129 194 0.105
muscle cell proliferation GO:0033002 52 0.105
vasodilation GO:0042311 28 0.105
b cell activation GO:0042113 161 0.104
regulation of striated muscle contraction GO:0006942 25 0.104
regulation of secretion GO:0051046 274 0.103
Mouse
hormone metabolic process GO:0042445 86 0.103
glycosyl compound metabolic process GO:1901657 246 0.102
neuroepithelial cell differentiation GO:0060563 37 0.102
striated muscle hypertrophy GO:0014897 24 0.102
regulation of organelle organization GO:0033043 289 0.101
regulation of nucleotide catabolic process GO:0030811 122 0.101
cardiac muscle hypertrophy GO:0003300 23 0.101
ureteric bud development GO:0001657 94 0.101
Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.101
striated muscle cell development GO:0055002 125 0.101
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.100
cerebral cortex development GO:0021987 86 0.100
Mouse
lung epithelial cell differentiation GO:0060487 29 0.100
carbohydrate metabolic process GO:0005975 230 0.100
Mouse
immune effector process GO:0002252 321 0.100
regulation of ras protein signal transduction GO:0046578 114 0.100
cellular divalent inorganic cation homeostasis GO:0072503 127 0.100
negative regulation of bmp signaling pathway GO:0030514 35 0.099
response to monosaccharide GO:0034284 67 0.099
Mouse
stem cell maintenance GO:0019827 130 0.099
regulation of leukocyte apoptotic process GO:2000106 56 0.099
Mouse
gtp metabolic process GO:0046039 144 0.099
glucose transport GO:0015758 56 0.098
divalent inorganic cation homeostasis GO:0072507 138 0.097
hepaticobiliary system development GO:0061008 67 0.096
nucleoside phosphate catabolic process GO:1901292 222 0.096
canonical wnt signaling pathway GO:0060070 130 0.096
positive regulation of cellular amine metabolic process GO:0033240 5 0.095
metanephric glomerular endothelium development GO:0072264 1 0.095
embryonic camera type eye development GO:0031076 36 0.095
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.095
limb development GO:0060173 166 0.095
posttranscriptional regulation of gene expression GO:0010608 155 0.095
chondrocyte hypertrophy GO:0003415 4 0.095
protein maturation GO:0051604 176 0.094
regulation of smad protein import into nucleus GO:0060390 3 0.094
energy derivation by oxidation of organic compounds GO:0015980 77 0.094
development of primary male sexual characteristics GO:0046546 88 0.094
purine nucleoside triphosphate metabolic process GO:0009144 226 0.094
odontogenesis of dentin containing tooth GO:0042475 66 0.094
positive regulation of neural precursor cell proliferation GO:2000179 42 0.093
Mouse
b cell proliferation GO:0042100 53 0.093
cellular response to lipopolysaccharide GO:0071222 77 0.093
divalent inorganic cation transport GO:0072511 178 0.093
neuron projection guidance GO:0097485 141 0.093
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.092
cellular response to peptide GO:1901653 92 0.092
Fly
carbohydrate derivative biosynthetic process GO:1901137 183 0.092
physiological muscle hypertrophy GO:0003298 3 0.092
endothelial cell migration GO:0043542 44 0.092
mitotic cell cycle process GO:1903047 159 0.092
lung cell differentiation GO:0060479 30 0.091
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 1 0.091
positive regulation of t cell activation GO:0050870 101 0.091
endocrine system development GO:0035270 98 0.090
regulation of glucocorticoid biosynthetic process GO:0031946 2 0.090
guanosine containing compound metabolic process GO:1901068 144 0.090
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.089
kidney epithelium development GO:0072073 121 0.089
Mouse
positive regulation of amino acid transport GO:0051957 4 0.089
brain morphogenesis GO:0048854 32 0.089
neuron projection extension GO:1990138 64 0.089
extrinsic apoptotic signaling pathway GO:0097191 126 0.088
negative regulation of wnt signaling pathway GO:0030178 73 0.088
nephron epithelium development GO:0072009 92 0.088
response to epidermal growth factor GO:0070849 4 0.088
cyclic nucleotide metabolic process GO:0009187 59 0.088
neuron migration GO:0001764 122 0.088
regulation of glomerular filtration GO:0003093 3 0.088
regulation of the force of heart contraction GO:0002026 17 0.088
peptide transport GO:0015833 133 0.087
Mouse
metanephric mesenchymal cell migration GO:0035789 2 0.087
forebrain neuron differentiation GO:0021879 52 0.087
septum primum development GO:0003284 4 0.087
endothelial cell differentiation GO:0045446 41 0.087
branchiomotor neuron axon guidance GO:0021785 7 0.087
cellular ion homeostasis GO:0006873 165 0.087
Mouse
cartilage development GO:0051216 140 0.086
Mouse
regulation of sodium ion transport GO:0002028 29 0.085
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.085
bone morphogenesis GO:0060349 78 0.085
single organism nuclear import GO:1902593 95 0.085
ovarian follicle development GO:0001541 40 0.084
regulation of bone mineralization GO:0030500 31 0.083
Mouse

Epas1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
kidney cancer DOID:263 0 0.386
urinary system cancer DOID:3996 0 0.386
renal cell carcinoma DOID:4450 0 0.386
renal carcinoma DOID:4451 0 0.386
cancer DOID:162 0 0.386
disease of cellular proliferation DOID:14566 0 0.386
organ system cancer DOID:0050686 0 0.386