Mus musculus

26 known processes

P2ry4

pyrimidinergic receptor P2Y, G-protein coupled, 4

(Aliases: P2Y4R,P2Y4)

P2ry4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of membrane potential GO:0042391 192 0.209
leukocyte activation involved in immune response GO:0002366 126 0.098
Mouse
male gamete generation GO:0048232 285 0.097
negative regulation of defense response GO:0031348 77 0.094
regulation of cytokine production GO:0001817 266 0.089
regulation of blood pressure GO:0008217 93 0.086
regulation of multi organism process GO:0043900 111 0.086
epithelial cell proliferation GO:0050673 174 0.083
leukocyte mediated immunity GO:0002443 174 0.083
cellular response to cytokine stimulus GO:0071345 189 0.081
regulation of secretion GO:0051046 274 0.075
Mouse
immune effector process GO:0002252 321 0.074
Mouse
sensory perception of light stimulus GO:0050953 54 0.068
regulation of cell activation GO:0050865 289 0.067
Mouse
wnt signaling pathway GO:0016055 188 0.067
negative regulation of immune effector process GO:0002698 55 0.065
skin development GO:0043588 220 0.064
regulation of defense response GO:0031347 233 0.062
Mouse
regulation of protein complex assembly GO:0043254 83 0.061
lymphocyte differentiation GO:0030098 242 0.059
Mouse
cellular amine metabolic process GO:0044106 44 0.059
multicellular organismal signaling GO:0035637 91 0.058
sensory perception of mechanical stimulus GO:0050954 107 0.058
regulation of cellular amine metabolic process GO:0033238 20 0.057
cytokine production GO:0001816 319 0.057
Mouse
cellular amino acid metabolic process GO:0006520 103 0.056
activation of immune response GO:0002253 138 0.056
Mouse
apoptotic signaling pathway GO:0097190 306 0.054
cell activation involved in immune response GO:0002263 126 0.054
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
carbohydrate derivative biosynthetic process GO:1901137 183 0.051
calcium ion transport GO:0006816 159 0.050
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.048
response to molecule of bacterial origin GO:0002237 143 0.048
Mouse
positive regulation of catecholamine secretion GO:0033605 2 0.048
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.046
epidermis development GO:0008544 187 0.044
spermatogenesis GO:0007283 284 0.044
regulation of body fluid levels GO:0050878 162 0.043
Mouse
negative regulation of growth GO:0045926 99 0.043
cell maturation GO:0048469 127 0.043
ear development GO:0043583 200 0.041
regulation of epithelial cell proliferation GO:0050678 141 0.041
response to lipopolysaccharide GO:0032496 128 0.039
Mouse
negative regulation of immune system process GO:0002683 209 0.039
inflammatory response GO:0006954 244 0.039
Mouse
camera type eye development GO:0043010 266 0.039
circulatory system process GO:0003013 197 0.038
regulation of cell migration GO:0030334 219 0.038
action potential GO:0001508 78 0.038
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.038
adaptive immune response GO:0002250 155 0.037
regulation of action potential GO:0098900 4 0.037
molting cycle GO:0042303 90 0.037
regulation of wnt signaling pathway GO:0030111 123 0.036
telencephalon development GO:0021537 186 0.036
cell cell junction organization GO:0045216 72 0.035
cell differentiation involved in embryonic placenta development GO:0060706 26 0.035
developmental maturation GO:0021700 193 0.035
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.034
morphogenesis of a branching structure GO:0001763 203 0.034
regulation of cellular component biogenesis GO:0044087 181 0.034
ensheathment of neurons GO:0007272 76 0.034
embryonic organ morphogenesis GO:0048562 276 0.033
innate immune response GO:0045087 157 0.033
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.032
spinal cord development GO:0021510 81 0.032
appendage development GO:0048736 166 0.032
placenta development GO:0001890 140 0.032
detection of stimulus GO:0051606 84 0.032
endodermal cell fate specification GO:0001714 4 0.032
epithelial cell development GO:0002064 159 0.032
regulation of muscle tissue development GO:1901861 97 0.031
transmission of nerve impulse GO:0019226 76 0.031
sensory perception GO:0007600 245 0.031
wound healing GO:0042060 157 0.031
muscle tissue development GO:0060537 308 0.031
proteoglycan metabolic process GO:0006029 38 0.030
skeletal muscle organ development GO:0060538 163 0.030
erythrocyte differentiation GO:0030218 88 0.030
cell fate specification GO:0001708 72 0.030
alpha beta t cell activation GO:0046631 91 0.030
regulation of tumor necrosis factor production GO:0032680 49 0.030
protein secretion GO:0009306 111 0.030
muscle cell differentiation GO:0042692 261 0.030
keratinocyte differentiation GO:0030216 48 0.030
amine metabolic process GO:0009308 45 0.029
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.029
muscle cell development GO:0055001 133 0.029
multi multicellular organism process GO:0044706 109 0.028
t cell activation GO:0042110 289 0.028
cation transport GO:0006812 399 0.028
Mouse
negative regulation of cytokine production GO:0001818 84 0.028
ventral spinal cord development GO:0021517 48 0.028
norepinephrine secretion GO:0048243 2 0.028
locomotory behavior GO:0007626 195 0.028
defense response to bacterium GO:0042742 119 0.027
homeostasis of number of cells GO:0048872 210 0.027
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.027
regulation of lymphocyte activation GO:0051249 240 0.027
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.027
regulation of cellular ketone metabolic process GO:0010565 66 0.026
cytokine mediated signaling pathway GO:0019221 115 0.026
ameboidal type cell migration GO:0001667 128 0.026
positive regulation of cell development GO:0010720 237 0.025
myeloid cell differentiation GO:0030099 233 0.025
negative regulation of multi organism process GO:0043901 68 0.025
axonogenesis GO:0007409 274 0.025
limb development GO:0060173 166 0.025
response to acid chemical GO:0001101 111 0.025
b cell activation GO:0042113 161 0.025
Mouse
mesodermal cell migration GO:0008078 4 0.025
interspecies interaction between organisms GO:0044419 83 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.024
regulation of secretion by cell GO:1903530 249 0.024
regulation of protein localization GO:0032880 231 0.024
regulation of ion homeostasis GO:2000021 64 0.024
protein processing GO:0016485 163 0.024
regulation of establishment of protein localization GO:0070201 181 0.023
acetylcholine secretion neurotransmission GO:0014055 2 0.023
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.023
defense response to other organism GO:0098542 197 0.023
macromolecule catabolic process GO:0009057 281 0.023
regionalization GO:0003002 337 0.023
cellular response to acid chemical GO:0071229 68 0.023
lymphocyte proliferation GO:0046651 164 0.023
Mouse
striated muscle tissue development GO:0014706 293 0.023
defense response to gram positive bacterium GO:0050830 50 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
lymphocyte mediated immunity GO:0002449 139 0.022
central nervous system neuron differentiation GO:0021953 162 0.022
divalent inorganic cation transport GO:0072511 178 0.022
Mouse
embryonic digit morphogenesis GO:0042733 56 0.022
cell killing GO:0001906 67 0.022
neuronal action potential GO:0019228 54 0.022
regulation of t cell activation GO:0050863 170 0.021
toll like receptor signaling pathway GO:0002224 38 0.021
regulation of anatomical structure size GO:0090066 178 0.021
protein maturation GO:0051604 176 0.021
cell differentiation in spinal cord GO:0021515 53 0.021
exocytosis GO:0006887 121 0.021
regulation of protein transport GO:0051223 163 0.021
cell fate commitment GO:0045165 210 0.021
regulation of leukocyte proliferation GO:0070663 121 0.021
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.020
peptidyl amino acid modification GO:0018193 336 0.020
positive regulation of keratinocyte proliferation GO:0010838 4 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.020
regulation of response to wounding GO:1903034 189 0.020
negative regulation of cell migration GO:0030336 59 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
regulation of adaptive immune response GO:0002819 90 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
sensory perception of sound GO:0007605 97 0.019
reflex GO:0060004 22 0.019
regulation of systemic arterial blood pressure GO:0003073 61 0.019
interferon gamma production GO:0032609 67 0.019
digestive system development GO:0055123 200 0.019
regulation of innate immune response GO:0045088 91 0.019
Mouse
cell junction organization GO:0034330 77 0.019
regulation of cell motility GO:2000145 236 0.019
regulation of cell projection organization GO:0031344 206 0.019
neuron migration GO:0001764 122 0.019
regulation of angiotensin levels in blood GO:0002002 4 0.019
canonical wnt signaling pathway GO:0060070 130 0.019
digestion GO:0007586 40 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
negative regulation of blood vessel morphogenesis GO:2000181 25 0.018
t cell differentiation GO:0030217 174 0.018
forebrain development GO:0030900 302 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.018
cellular response to inorganic substance GO:0071241 37 0.018
cellular lipid metabolic process GO:0044255 323 0.018
regulation of striated muscle cell differentiation GO:0051153 81 0.017
regulation of keratinocyte differentiation GO:0045616 11 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
positive regulation of defense response GO:0031349 124 0.017
Mouse
interleukin 6 production GO:0032635 58 0.017
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.017
ras protein signal transduction GO:0007265 77 0.017
leukocyte migration GO:0050900 124 0.017
lymphocyte activation involved in immune response GO:0002285 93 0.017
Mouse
negative regulation of cellular component organization GO:0051129 194 0.017
limb morphogenesis GO:0035108 149 0.017
striated muscle cell development GO:0055002 125 0.017
appendage morphogenesis GO:0035107 149 0.017
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.017
pharynx development GO:0060465 1 0.017
response to organonitrogen compound GO:0010243 246 0.016
negative regulation of hydrolase activity GO:0051346 71 0.016
regulation of epidermis development GO:0045682 33 0.016
gastrulation GO:0007369 116 0.016
regulation of myeloid cell differentiation GO:0045637 96 0.016
embryonic placenta development GO:0001892 98 0.016
negative regulation of cell activation GO:0050866 111 0.016
response to amino acid GO:0043200 37 0.016
response to inorganic substance GO:0010035 96 0.015
morphogenesis of a branching epithelium GO:0061138 193 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
positive regulation of epithelial cell proliferation GO:0050679 68 0.015
myelination GO:0042552 74 0.015
negative regulation of mesodermal cell fate specification GO:0042662 3 0.015
immune response activating signal transduction GO:0002757 116 0.015
Mouse
maintenance of location GO:0051235 89 0.015
negative regulation of cell development GO:0010721 169 0.015
regulation of protein secretion GO:0050708 82 0.015
positive regulation of protein modification process GO:0031401 299 0.015
bmp signaling pathway GO:0030509 93 0.015
fertilization GO:0009566 127 0.015
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.015
myotube differentiation GO:0014902 105 0.015
spinal cord motor neuron differentiation GO:0021522 35 0.015
tumor necrosis factor production GO:0032640 50 0.015
diencephalon development GO:0021536 63 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
negative regulation of molecular function GO:0044092 258 0.015
response to organic cyclic compound GO:0014070 198 0.014
axon ensheathment GO:0008366 76 0.014
response to growth factor GO:0070848 198 0.014
nucleotide metabolic process GO:0009117 332 0.014
hair cycle GO:0042633 90 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
regulation of feeding behavior GO:0060259 3 0.014
regulation of angiotensin metabolic process GO:0060177 4 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
nucleobase containing small molecule metabolic process GO:0055086 352 0.014
regulation of organ morphogenesis GO:2000027 144 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
innate immune response activating signal transduction GO:0002758 50 0.014
Mouse
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.014
glycoprotein metabolic process GO:0009100 116 0.014
regulation of myotube differentiation GO:0010830 62 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
microtubule based process GO:0007017 236 0.013
oxidation reduction process GO:0055114 342 0.013
negative regulation of protein modification process GO:0031400 163 0.013
lens development in camera type eye GO:0002088 62 0.013
regulation of proteolysis GO:0030162 164 0.013
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.013
chondroitin sulfate metabolic process GO:0030204 17 0.013
ear morphogenesis GO:0042471 118 0.013
regulation of growth of symbiont in host GO:0044126 19 0.013
norepinephrine transport GO:0015874 2 0.013
metencephalon development GO:0022037 89 0.013
neuropeptide signaling pathway GO:0007218 19 0.013
cell adhesion GO:0007155 329 0.013
detection of external stimulus GO:0009581 61 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
regulation of leukocyte mediated immunity GO:0002703 104 0.013
inflammatory response to antigenic stimulus GO:0002437 30 0.013
synaptic transmission GO:0007268 329 0.013
cardiac cell fate determination GO:0060913 2 0.013
negative regulation of cell motility GO:2000146 61 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
odontogenesis of dentin containing tooth GO:0042475 66 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
leukocyte differentiation GO:0002521 342 0.013
Mouse
immune response regulating signaling pathway GO:0002764 125 0.013
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.013
Mouse
blood circulation GO:0008015 195 0.013
cell type specific apoptotic process GO:0097285 268 0.013
negative regulation of epithelial cell proliferation GO:0050680 64 0.013
t cell mediated immunity GO:0002456 50 0.013
formation of primary germ layer GO:0001704 77 0.013
paramesonephric duct development GO:0061205 3 0.013
regulation of b cell activation GO:0050864 81 0.012
Mouse
primary neural tube formation GO:0014020 95 0.012
negative regulation of angiogenesis GO:0016525 25 0.012
cartilage development GO:0051216 140 0.012
regulation of inflammatory response GO:0050727 147 0.012
myeloid cell homeostasis GO:0002262 114 0.012
detection of abiotic stimulus GO:0009582 60 0.012
anatomical structure maturation GO:0071695 49 0.012
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
cellular ketone metabolic process GO:0042180 84 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.012
negative regulation of cell fate specification GO:0009996 4 0.012
cellular protein complex assembly GO:0043623 116 0.012
dephosphorylation GO:0016311 129 0.012
regulation of lymphocyte mediated immunity GO:0002706 84 0.012
middle ear morphogenesis GO:0042474 23 0.012
transmembrane transport GO:0055085 412 0.012
t cell activation involved in immune response GO:0002286 43 0.012
embryonic appendage morphogenesis GO:0035113 126 0.012
regulation of heart induction GO:0090381 2 0.012
positive regulation of phospholipase activity GO:0010518 3 0.012
t cell proliferation GO:0042098 120 0.012
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.012
cell substrate adhesion GO:0031589 130 0.012
regulation of peptidase activity GO:0052547 96 0.012
ventral spinal cord interneuron fate commitment GO:0060579 14 0.012
heart formation GO:0060914 16 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
respiratory tube development GO:0030323 167 0.012
positive regulation of cytokine production GO:0001819 174 0.012
cation transmembrane transport GO:0098655 266 0.012
organ growth GO:0035265 117 0.011
single fertilization GO:0007338 82 0.011
cardiac chamber development GO:0003205 108 0.011
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.011
regulation of system process GO:0044057 200 0.011
embryonic limb morphogenesis GO:0030326 126 0.011
endoderm development GO:0007492 45 0.011
bundle of his development GO:0003166 4 0.011
response to pain GO:0048265 26 0.011
regulation of cellular response to stress GO:0080135 159 0.011
embryonic heart tube morphogenesis GO:0003143 51 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
autonomic nervous system development GO:0048483 43 0.011
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
Mouse
negative regulation of secretion GO:0051048 61 0.011
glial cell fate commitment GO:0021781 14 0.011
positive regulation of cell death GO:0010942 224 0.011
positive regulation of cell activation GO:0050867 158 0.011
Mouse
endocrine system development GO:0035270 98 0.011
positive regulation of viral genome replication GO:0045070 2 0.011
positive regulation of ion transport GO:0043270 65 0.011
Mouse
av node cell to bundle of his cell communication GO:0086067 2 0.011
negative regulation of keratinocyte differentiation GO:0045617 4 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.011
positive regulation of viral entry into host cell GO:0046598 3 0.011
organic hydroxy compound transport GO:0015850 93 0.011
regulation of transmembrane transport GO:0034762 128 0.011
extracellular matrix organization GO:0030198 147 0.011
neural precursor cell proliferation GO:0061351 121 0.011
cellular response to abiotic stimulus GO:0071214 56 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
glial cell differentiation GO:0010001 131 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.010
regulation of protein catabolic process GO:0042176 108 0.010
organelle localization GO:0051640 179 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
cellular protein catabolic process GO:0044257 155 0.010
myeloid leukocyte activation GO:0002274 83 0.010
germ cell development GO:0007281 185 0.010
stem cell proliferation GO:0072089 117 0.010
membrane organization GO:0061024 245 0.010
circadian rhythm GO:0007623 114 0.010
response to uv GO:0009411 44 0.010
heart process GO:0003015 94 0.010
nerve development GO:0021675 67 0.010
regulation of hormone levels GO:0010817 211 0.010
regulation of neuron projection development GO:0010975 169 0.010
regulation of homeostatic process GO:0032844 182 0.010

P2ry4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.018
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.012
lipid metabolism disorder DOID:3146 0 0.012
inherited metabolic disorder DOID:655 0 0.012