Mus musculus

0 known processes

Pydc4

pyrin domain containing 4

(Aliases: E430029J22Rik,E030037K03Rik)

Pydc4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of defense response GO:0031347 233 0.128
immune effector process GO:0002252 321 0.121
cytokine production GO:0001816 319 0.110
innate immune response GO:0045087 157 0.094
negative regulation of immune system process GO:0002683 209 0.091
defense response to other organism GO:0098542 197 0.085
positive regulation of defense response GO:0031349 124 0.084
positive regulation of innate immune response GO:0045089 80 0.082
regulation of cytokine production GO:0001817 266 0.070
regulation of hydrolase activity GO:0051336 246 0.063
Mouse
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.062
cellular amino acid metabolic process GO:0006520 103 0.057
myeloid cell differentiation GO:0030099 233 0.049
negative regulation of protein metabolic process GO:0051248 282 0.049
Mouse
activation of immune response GO:0002253 138 0.048
positive regulation of cytokine production GO:0001819 174 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.046
regulation of innate immune response GO:0045088 91 0.045
defense response to virus GO:0051607 68 0.044
negative regulation of molecular function GO:0044092 258 0.044
Mouse
cellular amine metabolic process GO:0044106 44 0.043
activation of innate immune response GO:0002218 56 0.043
cellular ketone metabolic process GO:0042180 84 0.042
nucleobase containing small molecule metabolic process GO:0055086 352 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.041
nucleotide metabolic process GO:0009117 332 0.040
reactive oxygen species metabolic process GO:0072593 84 0.040
organic cyclic compound catabolic process GO:1901361 295 0.039
ras protein signal transduction GO:0007265 77 0.039
immune response regulating signaling pathway GO:0002764 125 0.039
protein modification by small protein conjugation GO:0032446 187 0.038
glycosyl compound metabolic process GO:1901657 246 0.038
small gtpase mediated signal transduction GO:0007264 97 0.038
purine nucleotide metabolic process GO:0006163 302 0.038
cellular response to biotic stimulus GO:0071216 92 0.038
response to molecule of bacterial origin GO:0002237 143 0.037
regulation of cellular ketone metabolic process GO:0010565 66 0.037
regulation of cellular amine metabolic process GO:0033238 20 0.036
cellular response to lipopolysaccharide GO:0071222 77 0.035
purine containing compound metabolic process GO:0072521 311 0.035
aromatic compound catabolic process GO:0019439 286 0.035
amine metabolic process GO:0009308 45 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.033
heterocycle catabolic process GO:0046700 280 0.033
organonitrogen compound catabolic process GO:1901565 264 0.032
macromolecule catabolic process GO:0009057 281 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
positive regulation of viral genome replication GO:0045070 2 0.032
protein processing GO:0016485 163 0.031
Mouse
organophosphate catabolic process GO:0046434 232 0.031
mapk cascade GO:0000165 281 0.031
regulation of cell activation GO:0050865 289 0.031
negative regulation of defense response GO:0031348 77 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.030
protein ubiquitination GO:0016567 171 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.030
regulation of proteolysis GO:0030162 164 0.030
Mouse
cation transport GO:0006812 399 0.030
negative regulation of hydrolase activity GO:0051346 71 0.030
Mouse
ribonucleotide metabolic process GO:0009259 291 0.029
nucleoside catabolic process GO:0009164 206 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
regulation of protein localization GO:0032880 231 0.029
rho protein signal transduction GO:0007266 32 0.029
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.029
response to lipopolysaccharide GO:0032496 128 0.029
apoptotic signaling pathway GO:0097190 306 0.028
t cell activation GO:0042110 289 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
regulation of establishment of protein localization GO:0070201 181 0.027
purine nucleoside triphosphate metabolic process GO:0009144 226 0.027
cellular response to lipid GO:0071396 145 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
regulation of lymphocyte activation GO:0051249 240 0.027
regulation of mapk cascade GO:0043408 248 0.027
immune response activating signal transduction GO:0002757 116 0.026
positive regulation of hydrolase activity GO:0051345 148 0.026
regulation of secretion by cell GO:1903530 249 0.026
regulation of organelle organization GO:0033043 289 0.026
nucleotide catabolic process GO:0009166 217 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
cellular macromolecule catabolic process GO:0044265 206 0.026
cellular homeostasis GO:0019725 240 0.026
leukocyte differentiation GO:0002521 342 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.025
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.025
positive regulation of viral entry into host cell GO:0046598 3 0.025
negative regulation of multi organism process GO:0043901 68 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
ossification GO:0001503 216 0.025
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.025
cellular response to cytokine stimulus GO:0071345 189 0.024
Mouse
purine containing compound catabolic process GO:0072523 213 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
ear development GO:0043583 200 0.024
Mouse
positive regulation of immune effector process GO:0002699 107 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
viral transcription GO:0019083 3 0.023
protein maturation GO:0051604 176 0.023
Mouse
cellular chemical homeostasis GO:0055082 215 0.023
modification dependent macromolecule catabolic process GO:0043632 133 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
negative regulation of protein processing GO:0010955 79 0.023
Mouse
regulation of multi organism process GO:0043900 111 0.023
nucleoside metabolic process GO:0009116 246 0.023
regulation of cellular catabolic process GO:0031329 242 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
cellular response to dna damage stimulus GO:0006974 207 0.023
regulation of protein transport GO:0051223 163 0.023
glycosyl compound catabolic process GO:1901658 206 0.023
regulation of cysteine type endopeptidase activity GO:2000116 65 0.022
Mouse
viral process GO:0016032 41 0.022
homeostasis of number of cells GO:0048872 210 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.022
negative regulation of viral transcription GO:0032897 3 0.022
ribonucleoside catabolic process GO:0042454 206 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
cellular response to molecule of bacterial origin GO:0071219 83 0.022
regulation of leukocyte mediated immunity GO:0002703 104 0.022
regulation of secretion GO:0051046 274 0.022
ubiquitin dependent protein catabolic process GO:0006511 129 0.022
regulation of protein processing GO:0070613 96 0.022
Mouse
cellular protein catabolic process GO:0044257 155 0.022
negative regulation of cell development GO:0010721 169 0.022
viral gene expression GO:0019080 3 0.022
leukocyte proliferation GO:0070661 172 0.021
inflammatory response GO:0006954 244 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
anion transport GO:0006820 177 0.021
muscle cell differentiation GO:0042692 261 0.021
cation transmembrane transport GO:0098655 266 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
positive regulation of mapk cascade GO:0043410 170 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.020
innate immune response activating signal transduction GO:0002758 50 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
response to organonitrogen compound GO:0010243 246 0.020
cation homeostasis GO:0055080 212 0.020
nitrogen compound transport GO:0071705 271 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
protein catabolic process GO:0030163 221 0.020
negative regulation of proteolysis GO:0045861 74 0.020
Mouse
cytoplasmic transport GO:0016482 234 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
cellular response to interferon alpha GO:0035457 4 0.019
Mouse
pattern recognition receptor signaling pathway GO:0002221 47 0.019
peptidyl amino acid modification GO:0018193 336 0.019
cellular lipid metabolic process GO:0044255 323 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.019
modification dependent protein catabolic process GO:0019941 133 0.019
positive regulation of protein modification process GO:0031401 299 0.019
lipid biosynthetic process GO:0008610 179 0.019
transmembrane transport GO:0055085 412 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.019
Mouse
cell type specific apoptotic process GO:0097285 268 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
g protein coupled receptor signaling pathway GO:0007186 243 0.019
regulation of protein maturation GO:1903317 96 0.018
Mouse
negative regulation of nervous system development GO:0051961 156 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
positive regulation of secretion GO:0051047 130 0.018
regulation of cell cycle GO:0051726 281 0.018
carbohydrate metabolic process GO:0005975 230 0.018
regulation of kinase activity GO:0043549 249 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
regulation of peptidase activity GO:0052547 96 0.018
Mouse
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.018
membrane organization GO:0061024 245 0.018
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.018
regulation of actin nucleation GO:0051125 4 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
negative regulation of protein maturation GO:1903318 79 0.017
Mouse
positive regulation of secretion by cell GO:1903532 114 0.017
dna metabolic process GO:0006259 303 0.017
intracellular protein transport GO:0006886 204 0.017
regulation of cell migration GO:0030334 219 0.017
regulation of cell motility GO:2000145 236 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
metal ion homeostasis GO:0055065 189 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
microtubule based process GO:0007017 236 0.017
oxidation reduction process GO:0055114 342 0.017
lymphocyte proliferation GO:0046651 164 0.017
response to acid chemical GO:0001101 111 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
regulation of ion transport GO:0043269 215 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
cytokine secretion GO:0050663 72 0.017
interleukin 6 production GO:0032635 58 0.016
anatomical structure homeostasis GO:0060249 145 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
ion transmembrane transport GO:0034220 361 0.016
negative regulation of endopeptidase activity GO:0010951 44 0.016
Mouse
regulation of intracellular transport GO:0032386 159 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
positive regulation of nervous system development GO:0051962 221 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
regulation of protein kinase activity GO:0045859 232 0.016
interspecies interaction between organisms GO:0044419 83 0.016
regulation of viral transcription GO:0046782 3 0.016
regulation of protein catabolic process GO:0042176 108 0.016
positive regulation of actin nucleation GO:0051127 3 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.016
proteasomal protein catabolic process GO:0010498 98 0.015
positive regulation of protein transport GO:0051222 93 0.015
regulation of interleukin 6 production GO:0032675 55 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
protein secretion GO:0009306 111 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
cellular ion homeostasis GO:0006873 165 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
endocytosis GO:0006897 168 0.015
regulation of ossification GO:0030278 112 0.015
Mouse
calcium ion homeostasis GO:0055074 127 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
regulation of anatomical structure size GO:0090066 178 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
regulation of cell projection organization GO:0031344 206 0.015
positive regulation of cell death GO:0010942 224 0.015
protein localization to organelle GO:0033365 185 0.015
regulation of transferase activity GO:0051338 263 0.015
regulation of inflammatory response GO:0050727 147 0.015
regulation of cellular component size GO:0032535 121 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
sequestering of metal ion GO:0051238 19 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
nuclear transport GO:0051169 139 0.014
muscle tissue development GO:0060537 308 0.014
regulation of hormone levels GO:0010817 211 0.014
positive regulation of cell activation GO:0050867 158 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
Mouse
maintenance of location GO:0051235 89 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of cellular response to stress GO:0080135 159 0.014
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.014
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.014
positive regulation of proteolysis GO:0045862 85 0.014
negative regulation of immune effector process GO:0002698 55 0.014
erythrocyte differentiation GO:0030218 88 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.013
cell adhesion GO:0007155 329 0.013
sensory perception GO:0007600 245 0.013
transepithelial chloride transport GO:0030321 4 0.013
regulation of lymphocyte mediated immunity GO:0002706 84 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
spermatogenesis GO:0007283 284 0.013
action potential GO:0001508 78 0.013
small molecule biosynthetic process GO:0044283 132 0.013
positive regulation of leukocyte mediated immunity GO:0002705 70 0.013
regulation of homeostatic process GO:0032844 182 0.013
regulation of neuron differentiation GO:0045664 281 0.013
viral genome replication GO:0019079 17 0.013
carbohydrate homeostasis GO:0033500 128 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.013
entry into other organism involved in symbiotic interaction GO:0051828 15 0.013
wound healing GO:0042060 157 0.013
cell killing GO:0001906 67 0.013
regulation of body fluid levels GO:0050878 162 0.013
regulation of system process GO:0044057 200 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
natural killer cell activation GO:0030101 44 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
glycoprotein metabolic process GO:0009100 116 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
mitotic cell cycle GO:0000278 195 0.013
negative regulation of phosphorylation GO:0042326 166 0.012
negative regulation of protein modification process GO:0031400 163 0.012
response to radiation GO:0009314 165 0.012
skeletal system development GO:0001501 356 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
multicellular organismal signaling GO:0035637 91 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
protein localization to nucleus GO:0034504 121 0.012
transmission of nerve impulse GO:0019226 76 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
leukocyte mediated immunity GO:0002443 174 0.012
alcohol metabolic process GO:0006066 116 0.012
striated muscle tissue development GO:0014706 293 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of membrane potential GO:0042391 192 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
nuclear import GO:0051170 95 0.012
negative regulation of viral process GO:0048525 23 0.012
organelle fission GO:0048285 170 0.012
peptide transport GO:0015833 133 0.012
tissue homeostasis GO:0001894 115 0.012
leukocyte mediated cytotoxicity GO:0001909 62 0.012
male gamete generation GO:0048232 285 0.012
blood vessel morphogenesis GO:0048514 285 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
response to peptide GO:1901652 136 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
dephosphorylation GO:0016311 129 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
response to nutrient levels GO:0031667 109 0.012
regulation of interleukin 8 production GO:0032677 3 0.012
protein polyubiquitination GO:0000209 33 0.012
regulation of response to biotic stimulus GO:0002831 38 0.012
sequestering of calcium ion GO:0051208 18 0.012
regulation of cytokine secretion GO:0050707 61 0.011
lymphocyte differentiation GO:0030098 242 0.011
positive regulation of endopeptidase activity GO:0010950 43 0.011
positive regulation of protein secretion GO:0050714 52 0.011
organelle localization GO:0051640 179 0.011
organelle assembly GO:0070925 177 0.011
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.011
organic anion transport GO:0015711 137 0.011
regulation of cell cycle process GO:0010564 160 0.011
cellular response to interferon beta GO:0035458 21 0.011
Mouse
fat cell differentiation GO:0045444 160 0.011
compound eye development GO:0048749 1 0.011
organic hydroxy compound transport GO:0015850 93 0.011
divalent inorganic cation transport GO:0072511 178 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
mitochondrion organization GO:0007005 134 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
chemotaxis GO:0006935 247 0.011
protein targeting GO:0006605 143 0.011
cellular response to acid chemical GO:0071229 68 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
cell activation involved in immune response GO:0002263 126 0.011
regulation of response to wounding GO:1903034 189 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.011
negative regulation of cell cycle GO:0045786 123 0.011
divalent metal ion transport GO:0070838 172 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
regulation of osteoblast differentiation GO:0045667 67 0.011
Mouse
negative regulation of peptidase activity GO:0010466 46 0.011
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
endomembrane system organization GO:0010256 147 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
regulation of cell killing GO:0031341 40 0.011
lipid transport GO:0006869 98 0.011
b cell activation GO:0042113 161 0.010
interleukin 8 production GO:0032637 4 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
interferon gamma production GO:0032609 67 0.010
gtp catabolic process GO:0006184 143 0.010
positive regulation of kinase activity GO:0033674 155 0.010
negative regulation of cell activation GO:0050866 111 0.010
positive regulation of protein catabolic process GO:0045732 60 0.010
amide transport GO:0042886 138 0.010
atp metabolic process GO:0046034 75 0.010
organism emergence from protective structure GO:0071684 4 0.010
positive regulation of nucleoside metabolic process GO:0045979 91 0.010
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.010
response to organic cyclic compound GO:0014070 198 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
retrograde transport endosome to golgi GO:0042147 2 0.010
cell division GO:0051301 120 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.010
interleukin 1 production GO:0032612 31 0.010
neuronal action potential GO:0019228 54 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
lateral inhibition GO:0046331 1 0.010

Pydc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.017
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
immune system disease DOID:2914 0 0.014
musculoskeletal system disease DOID:17 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
sensory system disease DOID:0050155 0 0.011