Mus musculus

0 known processes

Ibtk

inhibitor of Bruton agammaglobulinemia tyrosine kinase

(Aliases: mKIAA1417,BTKI,5430411K16Rik,AA409502)

Ibtk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.156
modification dependent macromolecule catabolic process GO:0043632 133 0.084
cellular protein catabolic process GO:0044257 155 0.073
cellular amine metabolic process GO:0044106 44 0.061
ubiquitin dependent protein catabolic process GO:0006511 129 0.059
chromatin organization GO:0006325 206 0.056
protein ubiquitination GO:0016567 171 0.054
cellular amino acid metabolic process GO:0006520 103 0.054
protein catabolic process GO:0030163 221 0.053
cellular macromolecule catabolic process GO:0044265 206 0.048
cellular response to dna damage stimulus GO:0006974 207 0.043
male gamete generation GO:0048232 285 0.042
negative regulation of protein metabolic process GO:0051248 282 0.041
Human
lateral inhibition GO:0046331 1 0.040
macromolecule catabolic process GO:0009057 281 0.039
negative regulation of intracellular signal transduction GO:1902532 167 0.038
amine metabolic process GO:0009308 45 0.036
fertilization GO:0009566 127 0.036
organelle localization GO:0051640 179 0.035
regulation of organelle organization GO:0033043 289 0.033
modification dependent protein catabolic process GO:0019941 133 0.033
chromatin modification GO:0016568 187 0.032
histone modification GO:0016570 159 0.032
peptidyl amino acid modification GO:0018193 336 0.032
Human
purine ribonucleoside catabolic process GO:0046130 205 0.031
glycoprotein biosynthetic process GO:0009101 89 0.031
purine ribonucleotide catabolic process GO:0009154 208 0.031
protein modification by small protein conjugation GO:0032446 187 0.031
endomembrane system organization GO:0010256 147 0.030
innate immune response GO:0045087 157 0.030
cellular response to cytokine stimulus GO:0071345 189 0.029
ras protein signal transduction GO:0007265 77 0.029
membrane organization GO:0061024 245 0.029
regulation of cellular amine metabolic process GO:0033238 20 0.028
small gtpase mediated signal transduction GO:0007264 97 0.028
compound eye development GO:0048749 1 0.027
regulation of hydrolase activity GO:0051336 246 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
protein polyubiquitination GO:0000209 33 0.026
cellular ketone metabolic process GO:0042180 84 0.026
glycosyl compound metabolic process GO:1901657 246 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
nucleotide metabolic process GO:0009117 332 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
spermatogenesis GO:0007283 284 0.023
mitotic cell cycle GO:0000278 195 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
organophosphate catabolic process GO:0046434 232 0.023
nucleoside metabolic process GO:0009116 246 0.023
ribose phosphate metabolic process GO:0019693 291 0.022
maintenance of location GO:0051235 89 0.022
Human
nucleoside phosphate catabolic process GO:1901292 222 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
negative regulation of molecular function GO:0044092 258 0.022
Human
glycoprotein metabolic process GO:0009100 116 0.021
nucleoside catabolic process GO:0009164 206 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
proteasomal protein catabolic process GO:0010498 98 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
negative regulation of immune system process GO:0002683 209 0.021
regulation of protein localization GO:0032880 231 0.021
translation GO:0006412 93 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
cation transport GO:0006812 399 0.021
Human
regulation of translation GO:0006417 71 0.020
organelle fission GO:0048285 170 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
aromatic compound catabolic process GO:0019439 286 0.020
protein localization to membrane GO:0072657 108 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
cytokine production GO:0001816 319 0.020
negative regulation of cell proliferation GO:0008285 296 0.019
gland development GO:0048732 330 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
localization within membrane GO:0051668 4 0.019
regulation of cell activation GO:0050865 289 0.019
forebrain development GO:0030900 302 0.019
covalent chromatin modification GO:0016569 163 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
regulation of proteolysis GO:0030162 164 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
apoptotic signaling pathway GO:0097190 306 0.018
gtp catabolic process GO:0006184 143 0.018
regulation of secretion GO:0051046 274 0.018
rhythmic process GO:0048511 174 0.018
purine containing compound metabolic process GO:0072521 311 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
regionalization GO:0003002 337 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
single organism cell adhesion GO:0098602 156 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
cellular homeostasis GO:0019725 240 0.017
Human
dna repair GO:0006281 107 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
protein maturation GO:0051604 176 0.017
establishment of organelle localization GO:0051656 122 0.016
mitochondrion organization GO:0007005 134 0.016
response to lipopolysaccharide GO:0032496 128 0.016
regulation of cellular ketone metabolic process GO:0010565 66 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
response to organonitrogen compound GO:0010243 246 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
Human
regulation of cell cycle GO:0051726 281 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
rho protein signal transduction GO:0007266 32 0.016
ossification GO:0001503 216 0.016
protein localization to organelle GO:0033365 185 0.015
cation transmembrane transport GO:0098655 266 0.015
vesicle organization GO:0016050 60 0.015
homeostasis of number of cells GO:0048872 210 0.015
regulation of cytokine production GO:0001817 266 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
actin cytoskeleton organization GO:0030036 220 0.015
t cell activation GO:0042110 289 0.015
regulation of ion transport GO:0043269 215 0.015
protein processing GO:0016485 163 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
response to oxidative stress GO:0006979 123 0.015
cellularization GO:0007349 1 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
regulation of cell cycle process GO:0010564 160 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
cellular response to lipid GO:0071396 145 0.015
tissue homeostasis GO:0001894 115 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
leukocyte differentiation GO:0002521 342 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
gonad development GO:0008406 141 0.014
macromolecule glycosylation GO:0043413 55 0.014
protein secretion GO:0009306 111 0.014
cytokinetic process GO:0032506 2 0.014
myeloid cell homeostasis GO:0002262 114 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
Human
regulation of chromosome organization GO:0033044 83 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
positive regulation of protein modification process GO:0031401 299 0.014
regulation of secretion by cell GO:1903530 249 0.014
cellular response to growth factor stimulus GO:0071363 197 0.013
mitotic cell cycle process GO:1903047 159 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
mitochondrion distribution GO:0048311 4 0.013
regulation of protein catabolic process GO:0042176 108 0.013
oxidation reduction process GO:0055114 342 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
actin filament organization GO:0007015 113 0.013
plasma membrane organization GO:0007009 90 0.013
purine containing compound catabolic process GO:0072523 213 0.013
carbohydrate metabolic process GO:0005975 230 0.013
regulation of chromosome segregation GO:0051983 21 0.013
germ cell development GO:0007281 185 0.013
cell adhesion GO:0007155 329 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
cation homeostasis GO:0055080 212 0.013
Human
divalent metal ion transport GO:0070838 172 0.013
Human
positive regulation of cell death GO:0010942 224 0.013
muscle tissue development GO:0060537 308 0.013
mitotic nuclear division GO:0007067 48 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
carbohydrate homeostasis GO:0033500 128 0.013
protein glycosylation GO:0006486 55 0.012
spermatid differentiation GO:0048515 115 0.012
intracellular protein transport GO:0006886 204 0.012
immune effector process GO:0002252 321 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
Human
response to growth factor GO:0070848 198 0.012
meiosis i GO:0007127 60 0.012
male meiosis i GO:0007141 16 0.012
cytoplasmic transport GO:0016482 234 0.012
Human
regulation of protein complex assembly GO:0043254 83 0.012
copii coated vesicle budding GO:0090114 2 0.012
placenta development GO:0001890 140 0.012
nucleotide catabolic process GO:0009166 217 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
cellular protein complex assembly GO:0043623 116 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
dna metabolic process GO:0006259 303 0.012
transmembrane transport GO:0055085 412 0.012
single fertilization GO:0007338 82 0.012
stem cell differentiation GO:0048863 268 0.012
wound healing GO:0042060 157 0.012
spermatid development GO:0007286 108 0.012
telencephalon development GO:0021537 186 0.012
regulation of protein transport GO:0051223 163 0.012
nitrogen compound transport GO:0071705 271 0.012
myeloid cell differentiation GO:0030099 233 0.011
gtp metabolic process GO:0046039 144 0.011
response to inorganic substance GO:0010035 96 0.011
positive regulation of cell activation GO:0050867 158 0.011
inflammatory response GO:0006954 244 0.011
regulation of cellular response to stress GO:0080135 159 0.011
response to acid chemical GO:0001101 111 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
epithelial cell development GO:0002064 159 0.011
negative regulation of protein modification process GO:0031400 163 0.011
Human
rna interference GO:0016246 2 0.011
nuclear division GO:0000280 158 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
regulation of membrane potential GO:0042391 192 0.011
anatomical structure homeostasis GO:0060249 145 0.011
blastocyst development GO:0001824 80 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
positive regulation of secretion GO:0051047 130 0.011
regulation of hormone levels GO:0010817 211 0.011
regulation of cell projection organization GO:0031344 206 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
positive regulation of organelle organization GO:0010638 128 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
Human
meiotic cell cycle process GO:1903046 77 0.011
positive regulation of nervous system development GO:0051962 221 0.011
cellular chemical homeostasis GO:0055082 215 0.011
Human
regulation of cell division GO:0051302 76 0.011
multi multicellular organism process GO:0044706 109 0.011
regulation of multi organism process GO:0043900 111 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
cellular lipid metabolic process GO:0044255 323 0.011
single organismal cell cell adhesion GO:0016337 131 0.010
response to nutrient levels GO:0031667 109 0.010
regulation of neuron differentiation GO:0045664 281 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
regulation of defense response GO:0031347 233 0.010
ion transmembrane transport GO:0034220 361 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
cell division GO:0051301 120 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
Human
female gamete generation GO:0007292 74 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
anion transport GO:0006820 177 0.010
heterocycle catabolic process GO:0046700 280 0.010
negative regulation of synapse assembly GO:0051964 3 0.010
mitotic sister chromatid separation GO:0051306 9 0.010
calcium ion transport GO:0006816 159 0.010
Human
regulation of response to wounding GO:1903034 189 0.010

Ibtk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
musculoskeletal system disease DOID:17 0 0.016
central nervous system disease DOID:331 0 0.015
neurodegenerative disease DOID:1289 0 0.015
sensory system disease DOID:0050155 0 0.011
disease of cellular proliferation DOID:14566 0 0.010
immune system disease DOID:2914 0 0.010