Mus musculus

0 known processes

Gcsh

glycine cleavage system protein H (aminomethyl carrier)

(Aliases: 5730591C18Rik,1100001L02Rik)

Gcsh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
alpha amino acid metabolic process GO:1901605 59 0.288
oxidation reduction process GO:0055114 342 0.210
response to oxygen radical GO:0000305 16 0.192
cellular amino acid metabolic process GO:0006520 103 0.176
nucleobase containing small molecule metabolic process GO:0055086 352 0.162
cellular modified amino acid metabolic process GO:0006575 63 0.157
dna metabolic process GO:0006259 303 0.137
transmembrane transport GO:0055085 412 0.130
cellular respiration GO:0045333 38 0.128
generation of precursor metabolites and energy GO:0006091 103 0.127
cellular aldehyde metabolic process GO:0006081 12 0.125
response to superoxide GO:0000303 16 0.113
mitochondrion organization GO:0007005 134 0.113
alpha amino acid biosynthetic process GO:1901607 15 0.100
cellular response to oxygen radical GO:0071450 14 0.089
cellular response to oxidative stress GO:0034599 76 0.080
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.078
neuron apoptotic process GO:0051402 142 0.078
protein processing GO:0016485 163 0.077
aromatic compound catabolic process GO:0019439 286 0.075
gland development GO:0048732 330 0.074
spermatogenesis GO:0007283 284 0.071
positive regulation of cell death GO:0010942 224 0.070
glycosyl compound metabolic process GO:1901657 246 0.070
male gamete generation GO:0048232 285 0.069
nucleoside phosphate metabolic process GO:0006753 338 0.068
removal of superoxide radicals GO:0019430 12 0.067
regulation of reactive oxygen species metabolic process GO:2000377 40 0.065
regulation of endopeptidase activity GO:0052548 89 0.062
apoptotic signaling pathway GO:0097190 306 0.060
regulation of apoptotic signaling pathway GO:2001233 197 0.060
regulation of membrane potential GO:0042391 192 0.060
amine metabolic process GO:0009308 45 0.059
protein maturation GO:0051604 176 0.057
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.055
coenzyme biosynthetic process GO:0009108 23 0.054
carboxylic acid biosynthetic process GO:0046394 86 0.052
regulation of ion transport GO:0043269 215 0.052
circulatory system process GO:0003013 197 0.052
intrinsic apoptotic signaling pathway GO:0097193 132 0.051
reactive oxygen species metabolic process GO:0072593 84 0.050
cellular lipid metabolic process GO:0044255 323 0.049
regulation of hydrolase activity GO:0051336 246 0.046
cellular ketone metabolic process GO:0042180 84 0.045
cation transport GO:0006812 399 0.045
cellular response to superoxide GO:0071451 14 0.044
aldehyde catabolic process GO:0046185 4 0.043
alcohol metabolic process GO:0006066 116 0.042
regulation of cellular catabolic process GO:0031329 242 0.042
organic cyclic compound catabolic process GO:1901361 295 0.042
small molecule biosynthetic process GO:0044283 132 0.042
multicellular organism growth GO:0035264 161 0.041
dna catabolic process endonucleolytic GO:0000737 15 0.041
response to inorganic substance GO:0010035 96 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
establishment of protein localization to organelle GO:0072594 118 0.039
negative regulation of molecular function GO:0044092 258 0.039
organonitrogen compound biosynthetic process GO:1901566 192 0.039
regulation of cysteine type endopeptidase activity GO:2000116 65 0.038
negative regulation of immune system process GO:0002683 209 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
ribose phosphate metabolic process GO:0019693 291 0.038
regulation of oxidative phosphorylation GO:0002082 6 0.037
regulation of nucleotide metabolic process GO:0006140 169 0.036
locomotory behavior GO:0007626 195 0.036
response to metal ion GO:0010038 47 0.036
cellular modified amino acid biosynthetic process GO:0042398 12 0.035
positive regulation of apoptotic process GO:0043065 217 0.035
cellular amino acid catabolic process GO:0009063 25 0.035
mitochondrial transport GO:0006839 36 0.034
small molecule catabolic process GO:0044282 71 0.034
hydrogen peroxide metabolic process GO:0042743 16 0.034
positive regulation of apoptotic signaling pathway GO:2001235 95 0.034
nucleotide metabolic process GO:0009117 332 0.034
negative regulation of protein metabolic process GO:0051248 282 0.033
regulation of transmembrane transport GO:0034762 128 0.033
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.033
regulation of nucleoside metabolic process GO:0009118 130 0.032
cellular amino acid biosynthetic process GO:0008652 22 0.032
inflammatory response GO:0006954 244 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
regulation of peptidase activity GO:0052547 96 0.032
cellular amine metabolic process GO:0044106 44 0.032
oxidative phosphorylation GO:0006119 14 0.031
defecation GO:0030421 1 0.031
cell type specific apoptotic process GO:0097285 268 0.031
reactive oxygen species biosynthetic process GO:1903409 8 0.030
positive regulation of hydrolase activity GO:0051345 148 0.030
positive regulation of programmed cell death GO:0043068 218 0.030
response to organonitrogen compound GO:0010243 246 0.030
cytokine production GO:0001816 319 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.029
heterocycle catabolic process GO:0046700 280 0.029
superoxide metabolic process GO:0006801 27 0.029
nitrogen compound transport GO:0071705 271 0.029
peptidyl amino acid modification GO:0018193 336 0.029
regulation of mitochondrial membrane potential GO:0051881 17 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.028
ribonucleoside metabolic process GO:0009119 245 0.028
purine ribonucleoside metabolic process GO:0046128 241 0.028
regulation of response to wounding GO:1903034 189 0.028
regulation of ion transmembrane transport GO:0034765 119 0.028
response to oxidative stress GO:0006979 123 0.027
atp metabolic process GO:0046034 75 0.027
purine containing compound metabolic process GO:0072521 311 0.027
heart process GO:0003015 94 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
intracellular receptor signaling pathway GO:0030522 74 0.025
neuron death GO:0070997 154 0.025
cellular homeostasis GO:0019725 240 0.025
cytoplasmic transport GO:0016482 234 0.025
muscle system process GO:0003012 141 0.024
positive regulation of protein modification process GO:0031401 299 0.024
apoptotic nuclear changes GO:0030262 9 0.024
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.024
cellular response to lipid GO:0071396 145 0.024
negative regulation of protein phosphorylation GO:0001933 126 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.023
negative regulation of neuron death GO:1901215 98 0.023
regulation of cell activation GO:0050865 289 0.023
organic hydroxy compound metabolic process GO:1901615 203 0.023
regulation of hormone levels GO:0010817 211 0.023
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.023
regulation of cytokine production GO:0001817 266 0.023
intracellular protein transport GO:0006886 204 0.023
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.023
organic acid catabolic process GO:0016054 51 0.023
regulation of cellular response to stress GO:0080135 159 0.022
heart contraction GO:0060047 93 0.022
cellular component disassembly involved in execution phase of apoptosis GO:0006921 9 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
blood circulation GO:0008015 195 0.022
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.021
response to reactive oxygen species GO:0000302 56 0.021
innate immune response GO:0045087 157 0.021
regulation of defense response GO:0031347 233 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
synaptic transmission GO:0007268 329 0.021
myeloid cell differentiation GO:0030099 233 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
regulation of neuron death GO:1901214 134 0.020
monocarboxylic acid metabolic process GO:0032787 191 0.020
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.020
organic acid biosynthetic process GO:0016053 86 0.020
immune effector process GO:0002252 321 0.020
regulation of proteolysis GO:0030162 164 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
homeostasis of number of cells GO:0048872 210 0.020
cellular response to lipopolysaccharide GO:0071222 77 0.020
lymphocyte mediated immunity GO:0002449 139 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
regulation of response to biotic stimulus GO:0002831 38 0.020
macromolecule catabolic process GO:0009057 281 0.020
mitochondrial translation GO:0032543 4 0.020
regulation of leukocyte differentiation GO:1902105 159 0.020
divalent metal ion transport GO:0070838 172 0.019
regulation of transporter activity GO:0032409 57 0.019
response to peptide GO:1901652 136 0.019
regulation of protein kinase activity GO:0045859 232 0.019
protein oxidation GO:0018158 2 0.019
negative regulation of protein modification process GO:0031400 163 0.018
interleukin 8 production GO:0032637 4 0.018
cellular response to biotic stimulus GO:0071216 92 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
fatty acid metabolic process GO:0006631 121 0.018
liver development GO:0001889 66 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
divalent inorganic cation transport GO:0072511 178 0.018
t cell activation GO:0042110 289 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
negative regulation of neuron apoptotic process GO:0043524 92 0.018
regulation of t cell activation GO:0050863 170 0.017
extrinsic apoptotic signaling pathway GO:0097191 126 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
4 hydroxyproline metabolic process GO:0019471 5 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
purine nucleoside monophosphate metabolic process GO:0009126 81 0.017
response to extracellular stimulus GO:0009991 127 0.017
regulation of cell motility GO:2000145 236 0.017
ion transmembrane transport GO:0034220 361 0.017
tissue homeostasis GO:0001894 115 0.017
hormone metabolic process GO:0042445 86 0.017
positive regulation of proteolysis GO:0045862 85 0.017
cofactor biosynthetic process GO:0051188 41 0.016
regulation of body fluid levels GO:0050878 162 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
positive regulation of growth GO:0045927 104 0.016
mitochondrial electron transport nadh to ubiquinone GO:0006120 4 0.016
regulation of neuron apoptotic process GO:0043523 122 0.016
positive regulation of peptidase activity GO:0010952 49 0.016
leukocyte mediated immunity GO:0002443 174 0.016
regulation of feeding behavior GO:0060259 3 0.015
negative regulation of oxidative stress induced cell death GO:1903202 9 0.015
regulation of inflammatory response GO:0050727 147 0.015
regulation of transferase activity GO:0051338 263 0.015
cellular response to molecule of bacterial origin GO:0071219 83 0.015
regulation of generation of precursor metabolites and energy GO:0043467 38 0.015
regulation of protein maturation GO:1903317 96 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
hepaticobiliary system development GO:0061008 67 0.015
adult behavior GO:0030534 135 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
regulation of removal of superoxide radicals GO:2000121 4 0.015
positive regulation of endopeptidase activity GO:0010950 43 0.015
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.015
positive regulation of cellular respiration GO:1901857 3 0.015
primary alcohol metabolic process GO:0034308 11 0.014
regulation of organelle organization GO:0033043 289 0.014
lymphocyte proliferation GO:0046651 164 0.014
anion transport GO:0006820 177 0.014
lipid biosynthetic process GO:0008610 179 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
cell proliferation in external granule layer GO:0021924 10 0.014
apoptotic dna fragmentation GO:0006309 7 0.014
regulation of nucleocytoplasmic transport GO:0046822 73 0.014
coenzyme metabolic process GO:0006732 52 0.014
regulation of blood pressure GO:0008217 93 0.014
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.014
response to oxygen levels GO:0070482 62 0.013
protein targeting to mitochondrion GO:0006626 6 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
cellular protein complex assembly GO:0043623 116 0.013
extracellular matrix organization GO:0030198 147 0.013
cell killing GO:0001906 67 0.013
dna catabolic process GO:0006308 19 0.013
energy derivation by oxidation of organic compounds GO:0015980 77 0.013
metal ion homeostasis GO:0055065 189 0.013
cofactor metabolic process GO:0051186 80 0.013
calcium ion transport GO:0006816 159 0.013
urogenital system development GO:0001655 261 0.013
neuron neuron synaptic transmission GO:0007270 69 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
protein catabolic process GO:0030163 221 0.013
amide transport GO:0042886 138 0.013
gonad development GO:0008406 141 0.013
regulation of protein processing GO:0070613 96 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.013
response to drug GO:0042493 75 0.013
regulation of protein transport GO:0051223 163 0.012
regulation of interleukin 8 production GO:0032677 3 0.012
retinoic acid metabolic process GO:0042573 12 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
positive regulation of interleukin 8 production GO:0032757 2 0.012
ketone catabolic process GO:0042182 3 0.012
positive regulation of cell development GO:0010720 237 0.012
extracellular structure organization GO:0043062 148 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
mitochondrion morphogenesis GO:0070584 13 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
forebrain development GO:0030900 302 0.012
sensory perception GO:0007600 245 0.012
cation transmembrane transport GO:0098655 266 0.012
positive regulation of ion transport GO:0043270 65 0.012
striated muscle tissue development GO:0014706 293 0.011
response to lipopolysaccharide GO:0032496 128 0.011
cation homeostasis GO:0055080 212 0.011
wound healing GO:0042060 157 0.011
regulation of kinase activity GO:0043549 249 0.011
respiratory burst GO:0045730 8 0.011
defense response to other organism GO:0098542 197 0.011
male sex differentiation GO:0046661 109 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
negative regulation of response to oxidative stress GO:1902883 10 0.011
negative regulation of transferase activity GO:0051348 85 0.011
heart morphogenesis GO:0003007 178 0.011
regulation of cellular response to oxidative stress GO:1900407 19 0.011
calcium ion homeostasis GO:0055074 127 0.011
sodium ion transport GO:0006814 73 0.011
negative regulation of t cell activation GO:0050868 65 0.011
epithelial cell proliferation GO:0050673 174 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.011
development of primary sexual characteristics GO:0045137 143 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
covalent chromatin modification GO:0016569 163 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
mapk cascade GO:0000165 281 0.011
leukocyte mediated cytotoxicity GO:0001909 62 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
response to hydrogen peroxide GO:0042542 32 0.011
regulation of muscle system process GO:0090257 80 0.011
nucleoside metabolic process GO:0009116 246 0.011
positive regulation of response to wounding GO:1903036 66 0.011
positive regulation of cytokine production GO:0001819 174 0.011
organic hydroxy compound transport GO:0015850 93 0.011
natural killer cell mediated cytotoxicity GO:0042267 29 0.010
protein targeting GO:0006605 143 0.010
cellular response to extracellular stimulus GO:0031668 81 0.010
regulation of intracellular transport GO:0032386 159 0.010
camera type eye development GO:0043010 266 0.010
regulation of binding GO:0051098 111 0.010
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.010
germ cell development GO:0007281 185 0.010
regulation of cellular respiration GO:0043457 10 0.010
peptide metabolic process GO:0006518 46 0.010
gtp catabolic process GO:0006184 143 0.010
leukocyte differentiation GO:0002521 342 0.010
nuclear transport GO:0051169 139 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
positive regulation of map kinase activity GO:0043406 84 0.010
membrane depolarization GO:0051899 64 0.010

Gcsh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.020
disease of anatomical entity DOID:7 0 0.020
blood coagulation disease DOID:1247 0 0.020
hematopoietic system disease DOID:74 0 0.020
central nervous system disease DOID:331 0 0.013
nervous system disease DOID:863 0 0.013
blood platelet disease DOID:2218 0 0.012
hemorrhagic disease DOID:2213 0 0.012