Mus musculus

19 known processes

Eif5a

eukaryotic translation initiation factor 5A

(Aliases: eIF-5A-1,D19Wsu54e,AA410058,Eif5a1,eIF-5A1,eIF-5A,MGC6725,eIF-4D,Eif4d)

Eif5a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pole plasm assembly GO:0007315 2 0.507
oocyte anterior posterior axis specification GO:0007314 2 0.435
oocyte axis specification GO:0007309 2 0.330
oocyte construction GO:0007308 2 0.292
microtubule cytoskeleton organization GO:0000226 157 0.257
alpha amino acid biosynthetic process GO:1901607 15 0.242
cellular amino acid metabolic process GO:0006520 103 0.179
germ cell development GO:0007281 185 0.164
translation GO:0006412 93 0.157
intracellular mrna localization GO:0008298 4 0.125
cellular response to dna damage stimulus GO:0006974 207 0.116
ribonucleoside metabolic process GO:0009119 245 0.097
mrna processing GO:0006397 63 0.092
spermatogenesis GO:0007283 284 0.087
male gamete generation GO:0048232 285 0.087
maternal determination of anterior posterior axis embryo GO:0008358 2 0.085
cellular protein complex assembly GO:0043623 116 0.082
apoptotic signaling pathway GO:0097190 306 0.082
microtubule based process GO:0007017 236 0.081
mrna splicing via spliceosome GO:0000398 43 0.076
aromatic compound catabolic process GO:0019439 286 0.075
purine ribonucleotide metabolic process GO:0009150 290 0.073
nucleotide catabolic process GO:0009166 217 0.071
stem cell development GO:0048864 219 0.069
nucleobase containing small molecule metabolic process GO:0055086 352 0.068
organonitrogen compound catabolic process GO:1901565 264 0.067
nucleoside phosphate catabolic process GO:1901292 222 0.066
regionalization GO:0003002 337 0.065
oocyte differentiation GO:0009994 35 0.064
nucleoside phosphate metabolic process GO:0006753 338 0.062
ribonucleotide catabolic process GO:0009261 208 0.059
developmental maturation GO:0021700 193 0.059
stem cell differentiation GO:0048863 268 0.058
ribose phosphate metabolic process GO:0019693 291 0.057
nucleoside triphosphate metabolic process GO:0009141 230 0.056
rna splicing via transesterification reactions GO:0000375 43 0.055
posttranscriptional regulation of gene expression GO:0010608 155 0.054
meiotic nuclear division GO:0007126 115 0.054
maintenance of location GO:0051235 89 0.054
cellular homeostasis GO:0019725 240 0.053
aspartate family amino acid metabolic process GO:0009066 10 0.052
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.052
alpha amino acid metabolic process GO:1901605 59 0.051
rna processing GO:0006396 105 0.051
nucleoside triphosphate catabolic process GO:0009143 205 0.050
purine containing compound metabolic process GO:0072521 311 0.050
regulation of mrna metabolic process GO:1903311 43 0.050
cell maturation GO:0048469 127 0.049
meiotic cell cycle GO:0051321 122 0.049
purine nucleotide metabolic process GO:0006163 302 0.049
regulation of cell motility GO:2000145 236 0.048
mrna metabolic process GO:0016071 84 0.048
purine nucleoside metabolic process GO:0042278 241 0.048
lateral inhibition GO:0046331 1 0.047
endocytosis GO:0006897 168 0.047
dna metabolic process GO:0006259 303 0.046
peptidyl amino acid modification GO:0018193 336 0.046
regulation of hydrolase activity GO:0051336 246 0.045
mitotic cell cycle process GO:1903047 159 0.045
nucleotide metabolic process GO:0009117 332 0.045
establishment of organelle localization GO:0051656 122 0.045
muscle cell differentiation GO:0042692 261 0.044
cell division GO:0051301 120 0.043
regulation of organelle organization GO:0033043 289 0.043
purine ribonucleoside metabolic process GO:0046128 241 0.043
regulation of translation GO:0006417 71 0.043
oocyte development GO:0048599 33 0.042
negative regulation of cellular component organization GO:0051129 194 0.042
cellular nitrogen compound catabolic process GO:0044270 280 0.042
chromosome segregation GO:0007059 48 0.040
centrosome organization GO:0051297 26 0.040
macromolecule catabolic process GO:0009057 281 0.039
cell adhesion GO:0007155 329 0.039
organelle assembly GO:0070925 177 0.039
organic cyclic compound catabolic process GO:1901361 295 0.038
nucleoside monophosphate metabolic process GO:0009123 85 0.038
intrinsic apoptotic signaling pathway GO:0097193 132 0.037
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.037
cellular amino acid biosynthetic process GO:0008652 22 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
nucleoside catabolic process GO:0009164 206 0.036
organophosphate catabolic process GO:0046434 232 0.036
cellularization GO:0007349 1 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.035
nucleoside metabolic process GO:0009116 246 0.035
modification dependent protein catabolic process GO:0019941 133 0.034
purine nucleoside triphosphate metabolic process GO:0009144 226 0.034
glycosyl compound metabolic process GO:1901657 246 0.033
purine nucleoside triphosphate catabolic process GO:0009146 203 0.033
carbohydrate metabolic process GO:0005975 230 0.033
purine nucleotide catabolic process GO:0006195 211 0.033
carbohydrate derivative biosynthetic process GO:1901137 183 0.032
regulation of apoptotic signaling pathway GO:2001233 197 0.032
regulation of cell migration GO:0030334 219 0.032
oogenesis GO:0048477 56 0.032
nuclear division GO:0000280 158 0.032
ubiquitin dependent protein catabolic process GO:0006511 129 0.031
organonitrogen compound biosynthetic process GO:1901566 192 0.031
purine nucleoside catabolic process GO:0006152 205 0.031
l serine metabolic process GO:0006563 2 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
striated muscle tissue development GO:0014706 293 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.030
cellular response to lipid GO:0071396 145 0.030
cytoplasmic transport GO:0016482 234 0.030
synaptic transmission GO:0007268 329 0.030
multi multicellular organism process GO:0044706 109 0.030
proteasomal protein catabolic process GO:0010498 98 0.029
regulation of nucleoside metabolic process GO:0009118 130 0.029
rna splicing GO:0008380 54 0.029
ras protein signal transduction GO:0007265 77 0.029
carboxylic acid biosynthetic process GO:0046394 86 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
glycosyl compound catabolic process GO:1901658 206 0.029
purine ribonucleoside catabolic process GO:0046130 205 0.028
mesenchymal cell development GO:0014031 93 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
regulation of cell cycle process GO:0010564 160 0.027
cation homeostasis GO:0055080 212 0.026
vesicle localization GO:0051648 86 0.026
negative regulation of cell cycle GO:0045786 123 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.026
cellular protein catabolic process GO:0044257 155 0.026
atp catabolic process GO:0006200 55 0.026
purine nucleoside monophosphate metabolic process GO:0009126 81 0.026
dna repair GO:0006281 107 0.026
metal ion homeostasis GO:0055065 189 0.025
positive regulation of protein modification process GO:0031401 299 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.025
single organism cell adhesion GO:0098602 156 0.024
response to oxidative stress GO:0006979 123 0.024
locomotory behavior GO:0007626 195 0.024
protein catabolic process GO:0030163 221 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
cellular ion homeostasis GO:0006873 165 0.024
double strand break repair GO:0006302 48 0.024
negative regulation of organelle organization GO:0010639 90 0.024
organelle localization GO:0051640 179 0.023
purine containing compound catabolic process GO:0072523 213 0.023
cellular amine metabolic process GO:0044106 44 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
receptor mediated endocytosis GO:0006898 51 0.023
spindle organization GO:0007051 28 0.023
response to organic cyclic compound GO:0014070 198 0.023
positive regulation of cell development GO:0010720 237 0.023
organelle fission GO:0048285 170 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
regulation of cellular ketone metabolic process GO:0010565 66 0.023
myosin filament organization GO:0031033 3 0.023
regulation of cell projection organization GO:0031344 206 0.023
myosin filament assembly GO:0031034 2 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.022
regulation of cell cycle GO:0051726 281 0.022
placenta development GO:0001890 140 0.022
membrane organization GO:0061024 245 0.022
lipid localization GO:0010876 126 0.022
muscle tissue development GO:0060537 308 0.022
regulation of mrna processing GO:0050684 41 0.021
oxidation reduction process GO:0055114 342 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
chromatin organization GO:0006325 206 0.021
segmentation GO:0035282 93 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
translational initiation GO:0006413 24 0.020
regulation of multi organism process GO:0043900 111 0.020
regulation of cellular component biogenesis GO:0044087 181 0.020
regulation of defense response GO:0031347 233 0.020
mitotic cell cycle GO:0000278 195 0.020
rna localization GO:0006403 23 0.020
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.020
regulation of mrna splicing via spliceosome GO:0048024 32 0.019
regulation of engulfment of apoptotic cell GO:1901074 2 0.019
female gamete generation GO:0007292 74 0.019
regulation of nuclear division GO:0051783 56 0.019
rhythmic process GO:0048511 174 0.019
trna aminoacylation for protein translation GO:0006418 1 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
positive regulation of chromosome segregation GO:0051984 4 0.019
muscle cell development GO:0055001 133 0.019
heterocycle catabolic process GO:0046700 280 0.019
purine nucleoside monophosphate catabolic process GO:0009128 58 0.019
mesenchyme development GO:0060485 152 0.019
protein polymerization GO:0051258 57 0.019
protein maturation GO:0051604 176 0.019
regulation of response to wounding GO:1903034 189 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
cellular ketone metabolic process GO:0042180 84 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
amine metabolic process GO:0009308 45 0.018
regulation of purine nucleotide catabolic process GO:0033121 122 0.018
calcium ion homeostasis GO:0055074 127 0.018
response to organonitrogen compound GO:0010243 246 0.018
regulation of anatomical structure size GO:0090066 178 0.017
regulation of rna splicing GO:0043484 37 0.017
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
meiosis i GO:0007127 60 0.017
regulation of intracellular transport GO:0032386 159 0.017
fertilization GO:0009566 127 0.017
regulation of cellular amine metabolic process GO:0033238 20 0.017
ribonucleoside monophosphate metabolic process GO:0009161 80 0.017
transmembrane transport GO:0055085 412 0.017
regulation of neuron projection development GO:0010975 169 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.017
chemotaxis GO:0006935 247 0.017
regulation of cell adhesion GO:0030155 154 0.017
regulation of kinase activity GO:0043549 249 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.016
development of primary sexual characteristics GO:0045137 143 0.016
regulation of reproductive process GO:2000241 66 0.016
positive regulation of mrna metabolic process GO:1903313 17 0.016
ribonucleoside biosynthetic process GO:0042455 21 0.016
regulation of mitotic cell cycle phase transition GO:1901990 73 0.015
histone modification GO:0016570 159 0.015
glutamine family amino acid biosynthetic process GO:0009084 2 0.015
actin cytoskeleton organization GO:0030036 220 0.015
muscle system process GO:0003012 141 0.015
blood vessel morphogenesis GO:0048514 285 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.015
maternal placenta development GO:0001893 20 0.015
maternal process involved in female pregnancy GO:0060135 32 0.015
macromolecule methylation GO:0043414 120 0.015
inflammatory response GO:0006954 244 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
negative regulation of protein metabolic process GO:0051248 282 0.014
immune effector process GO:0002252 321 0.014
meiotic cell cycle process GO:1903046 77 0.014
circulatory system process GO:0003013 197 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
lipid storage GO:0019915 36 0.014
trna metabolic process GO:0006399 11 0.014
nitrogen compound transport GO:0071705 271 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
carboxylic acid catabolic process GO:0046395 51 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
carbohydrate homeostasis GO:0033500 128 0.014
regulation of cellular component size GO:0032535 121 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
regulation of dendritic cell chemotaxis GO:2000508 1 0.013
angiogenesis GO:0001525 201 0.013
response to testosterone GO:0033574 3 0.013
spermatid development GO:0007286 108 0.013
cellular chemical homeostasis GO:0055082 215 0.013
cell type specific apoptotic process GO:0097285 268 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
regulation of cell cycle phase transition GO:1901987 77 0.013
regulation of cell substrate adhesion GO:0010810 73 0.013
regulation of neuron differentiation GO:0045664 281 0.013
macromolecule glycosylation GO:0043413 55 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
dna recombination GO:0006310 92 0.013
mesenchymal cell differentiation GO:0048762 107 0.013
circadian regulation of gene expression GO:0032922 48 0.013
striated muscle cell development GO:0055002 125 0.013
negative regulation of cell development GO:0010721 169 0.013
regulation of cell division GO:0051302 76 0.013
regulation of protein processing GO:0070613 96 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
pigment biosynthetic process GO:0046148 26 0.012
mitotic nuclear division GO:0007067 48 0.012
body morphogenesis GO:0010171 45 0.012
protein glycosylation GO:0006486 55 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
regulation of cellular response to stress GO:0080135 159 0.012
compound eye development GO:0048749 1 0.012
ameboidal type cell migration GO:0001667 128 0.012
regulation of protein maturation GO:1903317 96 0.012
cellular response to oxidative stress GO:0034599 76 0.012
regulation of cytokine production GO:0001817 266 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.012
protein processing GO:0016485 163 0.012
heart morphogenesis GO:0003007 178 0.012
exocytosis GO:0006887 121 0.012
glycoprotein metabolic process GO:0009100 116 0.011
epithelial cell development GO:0002064 159 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
response to acid chemical GO:0001101 111 0.011
sensory perception GO:0007600 245 0.011
chromatin modification GO:0016568 187 0.011
neurotransmitter transport GO:0006836 76 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
anterior posterior axis specification embryo GO:0008595 9 0.011
gonad development GO:0008406 141 0.011
methylation GO:0032259 134 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
protein ubiquitination GO:0016567 171 0.011
positive regulation of cell motility GO:2000147 116 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
purine nucleobase metabolic process GO:0006144 4 0.011
blood circulation GO:0008015 195 0.011
cation transport GO:0006812 399 0.011
response to alcohol GO:0097305 48 0.011
circadian rhythm GO:0007623 114 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
intracellular protein transport GO:0006886 204 0.010
regulation of body fluid levels GO:0050878 162 0.010
positive regulation of cell death GO:0010942 224 0.010
cellular lipid metabolic process GO:0044255 323 0.010
ribonucleoprotein complex subunit organization GO:0071826 28 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
establishment of vesicle localization GO:0051650 81 0.010
response to temperature stimulus GO:0009266 55 0.010
synaptic vesicle transport GO:0048489 57 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
establishment or maintenance of cell polarity GO:0007163 86 0.010
positive regulation of mrna processing GO:0050685 16 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
negative regulation of protein maturation GO:1903318 79 0.010

Eif5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.093
disease of anatomical entity DOID:7 0 0.093
nervous system disease DOID:863 0 0.093
neurodegenerative disease DOID:1289 0 0.070
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.022
motor neuron disease DOID:231 0 0.016