Mus musculus

0 known processes

Sirt7

sirtuin 7 (silent mating type information regulation 2, homolog) 7 (S. cerevisiae)

(Aliases: MGC37560,MGC31235)

Sirt7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton organization GO:0030036 220 0.081
apoptotic signaling pathway GO:0097190 306 0.078
peptidyl amino acid modification GO:0018193 336 0.076
cellular ketone metabolic process GO:0042180 84 0.076
regulation of cellular ketone metabolic process GO:0010565 66 0.068
peptidyl tyrosine modification GO:0018212 145 0.067
transmembrane transport GO:0055085 412 0.065
ras protein signal transduction GO:0007265 77 0.064
amine metabolic process GO:0009308 45 0.059
nitrogen compound transport GO:0071705 271 0.058
negative regulation of molecular function GO:0044092 258 0.057
protein modification by small protein conjugation GO:0032446 187 0.054
negative regulation of phosphorus metabolic process GO:0010563 184 0.054
regulation of cellular amino acid metabolic process GO:0006521 5 0.053
protein modification by small protein conjugation or removal GO:0070647 207 0.052
cellular amino acid metabolic process GO:0006520 103 0.051
protein ubiquitination GO:0016567 171 0.051
ion transmembrane transport GO:0034220 361 0.050
skin development GO:0043588 220 0.045
regulation of defense response GO:0031347 233 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.045
cation transport GO:0006812 399 0.043
small gtpase mediated signal transduction GO:0007264 97 0.043
epidermis development GO:0008544 187 0.042
cellular amine metabolic process GO:0044106 44 0.042
mapk cascade GO:0000165 281 0.041
regulation of cell cycle GO:0051726 281 0.041
regulation of cellular component biogenesis GO:0044087 181 0.041
organic cyclic compound catabolic process GO:1901361 295 0.040
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.040
extrinsic apoptotic signaling pathway GO:0097191 126 0.039
divalent inorganic cation transport GO:0072511 178 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
microtubule based process GO:0007017 236 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.037
negative regulation of immune system process GO:0002683 209 0.037
intracellular protein transport GO:0006886 204 0.037
regulation of cell activation GO:0050865 289 0.036
regulation of apoptotic signaling pathway GO:2001233 197 0.036
aromatic compound catabolic process GO:0019439 286 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.036
regulation of actin nucleation GO:0051125 4 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
retrograde transport endosome to golgi GO:0042147 2 0.035
nucleoside phosphate catabolic process GO:1901292 222 0.034
regulation of organelle organization GO:0033043 289 0.034
regulation of mapk cascade GO:0043408 248 0.033
positive regulation of programmed cell death GO:0043068 218 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
cellular homeostasis GO:0019725 240 0.033
negative regulation of phosphorylation GO:0042326 166 0.032
peptide transport GO:0015833 133 0.031
protein localization to nucleus GO:0034504 121 0.031
cellular protein complex assembly GO:0043623 116 0.031
regulation of hydrolase activity GO:0051336 246 0.031
purine ribonucleotide catabolic process GO:0009154 208 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.031
cation transmembrane transport GO:0098655 266 0.031
negative regulation of cellular amine metabolic process GO:0033239 1 0.030
positive regulation of apoptotic process GO:0043065 217 0.030
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.030
purine containing compound catabolic process GO:0072523 213 0.030
heterocycle catabolic process GO:0046700 280 0.030
cellular response to cytokine stimulus GO:0071345 189 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
nucleotide catabolic process GO:0009166 217 0.029
regulation of ion transport GO:0043269 215 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
g protein coupled receptor signaling pathway GO:0007186 243 0.028
peptidyl tyrosine phosphorylation GO:0018108 143 0.028
vesicle organization GO:0016050 60 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
regulation of purine nucleotide metabolic process GO:1900542 169 0.028
actin filament organization GO:0007015 113 0.028
cytoplasmic transport GO:0016482 234 0.028
positive regulation of apoptotic signaling pathway GO:2001235 95 0.027
purine containing compound metabolic process GO:0072521 311 0.027
regulation of ras protein signal transduction GO:0046578 114 0.027
histone modification GO:0016570 159 0.027
Human
embryonic organ morphogenesis GO:0048562 276 0.027
regulation of cellular catabolic process GO:0031329 242 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
cellular lipid metabolic process GO:0044255 323 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
ribonucleoside metabolic process GO:0009119 245 0.027
positive regulation of actin nucleation GO:0051127 3 0.026
protein maturation GO:0051604 176 0.026
regulation of actin cytoskeleton organization GO:0032956 84 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
regulation of t cell activation GO:0050863 170 0.026
gtp catabolic process GO:0006184 143 0.026
amide transport GO:0042886 138 0.026
purine nucleotide catabolic process GO:0006195 211 0.025
cytokine production GO:0001816 319 0.025
myosin filament organization GO:0031033 3 0.025
regulation of kinase activity GO:0043549 249 0.025
protein targeting GO:0006605 143 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
endomembrane system organization GO:0010256 147 0.025
cation homeostasis GO:0055080 212 0.025
organelle fission GO:0048285 170 0.025
Human
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.024
positive regulation of mapk cascade GO:0043410 170 0.024
nucleotide metabolic process GO:0009117 332 0.024
immune response regulating signaling pathway GO:0002764 125 0.024
cell type specific apoptotic process GO:0097285 268 0.024
negative regulation of phosphate metabolic process GO:0045936 184 0.024
regulation of vesicle mediated transport GO:0060627 139 0.024
regulation of cytokine production GO:0001817 266 0.024
dephosphorylation GO:0016311 129 0.023
metal ion homeostasis GO:0055065 189 0.023
negative regulation of inflammatory response GO:0050728 61 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
membrane organization GO:0061024 245 0.023
regulation of transferase activity GO:0051338 263 0.023
regulation of hormone levels GO:0010817 211 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
nucleoside catabolic process GO:0009164 206 0.022
nucleoside metabolic process GO:0009116 246 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
nuclear transport GO:0051169 139 0.022
myeloid cell differentiation GO:0030099 233 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
protein processing GO:0016485 163 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
dna metabolic process GO:0006259 303 0.022
spermatogenesis GO:0007283 284 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
myosin filament assembly GO:0031034 2 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.021
alcohol metabolic process GO:0006066 116 0.021
negative regulation of defense response GO:0031348 77 0.021
regulation of gtp catabolic process GO:0033124 113 0.021
rho protein signal transduction GO:0007266 32 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
striated muscle myosin thick filament assembly GO:0071688 1 0.021
positive regulation of cell death GO:0010942 224 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
sequestering of calcium ion GO:0051208 18 0.020
divalent metal ion transport GO:0070838 172 0.020
innate immune response GO:0045087 157 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
protein polymerization GO:0051258 57 0.020
regulation of cytoskeleton organization GO:0051493 122 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
positive regulation of cellular catabolic process GO:0031331 148 0.020
regulation of body fluid levels GO:0050878 162 0.020
response to growth factor GO:0070848 198 0.020
positive regulation of protein modification process GO:0031401 299 0.020
plasma membrane organization GO:0007009 90 0.020
cellular macromolecule catabolic process GO:0044265 206 0.019
regulation of endocytosis GO:0030100 69 0.019
regulation of inflammatory response GO:0050727 147 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
calcium ion transport GO:0006816 159 0.019
sensory perception GO:0007600 245 0.019
regulation of intracellular transport GO:0032386 159 0.019
protein polyubiquitination GO:0000209 33 0.019
cell adhesion GO:0007155 329 0.019
regulation of purine nucleotide catabolic process GO:0033121 122 0.019
entry into host GO:0044409 15 0.019
homeostasis of number of cells GO:0048872 210 0.019
muscle cell differentiation GO:0042692 261 0.018
regulation of protein kinase activity GO:0045859 232 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
sequestering of metal ion GO:0051238 19 0.018
organophosphate catabolic process GO:0046434 232 0.018
regulation of protein maturation GO:1903317 96 0.018
lymphocyte proliferation GO:0046651 164 0.018
mitochondrion organization GO:0007005 134 0.018
golgi to endosome transport GO:0006895 3 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
cellular ion homeostasis GO:0006873 165 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
negative regulation of cell development GO:0010721 169 0.018
endocytosis GO:0006897 168 0.017
gland development GO:0048732 330 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
regulation of homeostatic process GO:0032844 182 0.017
maintenance of location GO:0051235 89 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
t cell activation GO:0042110 289 0.017
cytokine mediated signaling pathway GO:0019221 115 0.017
cellular calcium ion homeostasis GO:0006874 119 0.017
protein localization to organelle GO:0033365 185 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
macromolecule catabolic process GO:0009057 281 0.017
regulation of protein transport GO:0051223 163 0.017
response to light stimulus GO:0009416 135 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
compound eye development GO:0048749 1 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
regulation of secretion by cell GO:1903530 249 0.017
negative regulation of necroptotic process GO:0060546 9 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
regulation of cellular response to stress GO:0080135 159 0.017
regulation of response to wounding GO:1903034 189 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
cellular chemical homeostasis GO:0055082 215 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.016
cell division GO:0051301 120 0.016
regulation of protein complex assembly GO:0043254 83 0.016
cellular protein catabolic process GO:0044257 155 0.016
protein import into nucleus GO:0006606 95 0.016
regulation of secretion GO:0051046 274 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
regulation of actin filament based process GO:0032970 99 0.016
striated muscle tissue development GO:0014706 293 0.016
immune effector process GO:0002252 321 0.016
activation of immune response GO:0002253 138 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
negative regulation of cytokine production GO:0001818 84 0.016
male gamete generation GO:0048232 285 0.016
actin polymerization or depolymerization GO:0008154 54 0.015
t cell proliferation GO:0042098 120 0.015
muscle cell development GO:0055001 133 0.015
regulation of anatomical structure size GO:0090066 178 0.015
carbohydrate metabolic process GO:0005975 230 0.015
Mouse
cell chemotaxis GO:0060326 81 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
positive regulation of protein transport GO:0051222 93 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
actin filament polymerization GO:0030041 44 0.015
peptide secretion GO:0002790 114 0.015
regulation of innate immune response GO:0045088 91 0.015
nuclear import GO:0051170 95 0.015
anion transport GO:0006820 177 0.015
single organism nuclear import GO:1902593 95 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
regulation of protein processing GO:0070613 96 0.015
camera type eye development GO:0043010 266 0.015
myeloid cell homeostasis GO:0002262 114 0.015
erk1 and erk2 cascade GO:0070371 77 0.015
regulation of ras gtpase activity GO:0032318 88 0.015
progesterone metabolic process GO:0042448 4 0.015
regulation of intracellular protein transport GO:0033157 82 0.015
positive regulation of cell development GO:0010720 237 0.015
interspecies interaction between organisms GO:0044419 83 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
regulation of metal ion transport GO:0010959 106 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
arp2 3 complex mediated actin nucleation GO:0034314 3 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
organelle localization GO:0051640 179 0.014
spermatid differentiation GO:0048515 115 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
Mouse
meiotic nuclear division GO:0007126 115 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
neural precursor cell proliferation GO:0061351 121 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
leukocyte proliferation GO:0070661 172 0.014
mitotic cell cycle process GO:1903047 159 0.014
Human
i kappab kinase nf kappab signaling GO:0007249 85 0.014
positive regulation of cell activation GO:0050867 158 0.014
mitotic cell cycle GO:0000278 195 0.014
Human
iron sulfur cluster assembly GO:0016226 3 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
positive regulation of transferase activity GO:0051347 167 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
skeletal system development GO:0001501 356 0.014
regulation of cell migration GO:0030334 219 0.014
regulation of engulfment of apoptotic cell GO:1901074 2 0.014
leukocyte differentiation GO:0002521 342 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.013
response to radiation GO:0009314 165 0.013
monosaccharide metabolic process GO:0005996 106 0.013
positive regulation of kinase activity GO:0033674 155 0.013
calcium ion homeostasis GO:0055074 127 0.013
ear development GO:0043583 200 0.013
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
negative regulation of kinase activity GO:0033673 81 0.013
peptidyl serine modification GO:0018209 83 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
inflammatory response GO:0006954 244 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
regulation of proteolysis GO:0030162 164 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
chromatin modification GO:0016568 187 0.013
Human
cognition GO:0050890 149 0.013
negative regulation of cell activation GO:0050866 111 0.013
lung development GO:0030324 164 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
regulation of ion homeostasis GO:2000021 64 0.013
tissue homeostasis GO:0001894 115 0.013
small molecule biosynthetic process GO:0044283 132 0.013
regulation of cell projection organization GO:0031344 206 0.013
erythrocyte differentiation GO:0030218 88 0.013
oxidation reduction process GO:0055114 342 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
respiratory system development GO:0060541 190 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
negative regulation of transferase activity GO:0051348 85 0.012
positive regulation of organelle organization GO:0010638 128 0.012
neuron death GO:0070997 154 0.012
positive regulation of viral entry into host cell GO:0046598 3 0.012
regulation of t cell proliferation GO:0042129 92 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
regulation of protein localization GO:0032880 231 0.012
regulation of peptide transport GO:0090087 91 0.012
toll like receptor signaling pathway GO:0002224 38 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
gtp metabolic process GO:0046039 144 0.012
regulation of cellular component size GO:0032535 121 0.012
regulation of cell motility GO:2000145 236 0.012
meiotic cell cycle GO:0051321 122 0.012
developmental maturation GO:0021700 193 0.012
germ cell development GO:0007281 185 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.012
b cell activation GO:0042113 161 0.012
response to acid chemical GO:0001101 111 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.012
muscle tissue development GO:0060537 308 0.012
defense response to other organism GO:0098542 197 0.012
synaptic transmission GO:0007268 329 0.012
regulation of peptidase activity GO:0052547 96 0.012
keratinocyte differentiation GO:0030216 48 0.012
transcription from rna polymerase iii promoter GO:0006383 3 0.012
organelle assembly GO:0070925 177 0.012
positive regulation of ras gtpase activity GO:0032320 65 0.012
negative regulation of protein tyrosine kinase activity GO:0061099 3 0.012
positive regulation of reverse cholesterol transport GO:1903064 1 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
neuron neuron synaptic transmission GO:0007270 69 0.012
skeletal system morphogenesis GO:0048705 203 0.012
adult behavior GO:0030534 135 0.012
protein localization to plasma membrane GO:0072659 57 0.012
cytokine biosynthetic process GO:0042089 68 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.011
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.011
regionalization GO:0003002 337 0.011
mitotic cytokinesis GO:0000281 4 0.011
neuron apoptotic process GO:0051402 142 0.011
peptide hormone secretion GO:0030072 109 0.011
regulation of membrane potential GO:0042391 192 0.011
pattern recognition receptor signaling pathway GO:0002221 47 0.011
glycoprotein metabolic process GO:0009100 116 0.011
Mouse
glucose homeostasis GO:0042593 128 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
glucose metabolic process GO:0006006 92 0.011
steroid metabolic process GO:0008202 119 0.011
lipid transport GO:0006869 98 0.011
tube formation GO:0035148 140 0.011
hexose metabolic process GO:0019318 98 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
cellular response to lipid GO:0071396 145 0.011
protein import GO:0017038 101 0.011
adult locomotory behavior GO:0008344 91 0.011
negative regulation of protein modification process GO:0031400 163 0.011
negative regulation of immune effector process GO:0002698 55 0.011
regulation of feeding behavior GO:0060259 3 0.011
negative regulation of cell cycle GO:0045786 123 0.011
anatomical structure homeostasis GO:0060249 145 0.011
peptidyl serine phosphorylation GO:0018105 74 0.011
regulation of clathrin mediated endocytosis GO:2000369 4 0.011
photoreceptor cell maintenance GO:0045494 19 0.011
histone threonine phosphorylation GO:0035405 1 0.011
protein autophosphorylation GO:0046777 61 0.011
blood vessel morphogenesis GO:0048514 285 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
regulation of system process GO:0044057 200 0.011
negative regulation of necrotic cell death GO:0060547 11 0.011
regulation of calcium ion transport GO:0051924 69 0.011
response to lipopolysaccharide GO:0032496 128 0.011
positive regulation of defense response GO:0031349 124 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
negative regulation of protein processing GO:0010955 79 0.010
chromatin organization GO:0006325 206 0.010
Human
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.010
regulation of neuron death GO:1901214 134 0.010
hormone secretion GO:0046879 128 0.010
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.010
lateral inhibition GO:0046331 1 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.010
forebrain development GO:0030900 302 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
protein catabolic process GO:0030163 221 0.010
viral gene expression GO:0019080 3 0.010
sensory system development GO:0048880 3 0.010
sensory organ morphogenesis GO:0090596 242 0.010
exocytosis GO:0006887 121 0.010

Sirt7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.028
inherited metabolic disorder DOID:655 0 0.020
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
central nervous system disease DOID:331 0 0.017
immune system disease DOID:2914 0 0.017