Mus musculus

108 known processes

Six5

sine oculis-related homeobox 5 homolog (Drosophila)

(Aliases: TrexBF,MDMAHP,Dmahp)

Six5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ morphogenesis GO:0048562 276 0.958
Mouse
epithelial tube morphogenesis GO:0060562 303 0.869
Mouse
morphogenesis of a branching structure GO:0001763 203 0.675
Mouse
skeletal system morphogenesis GO:0048705 203 0.658
Mouse
lung development GO:0030324 164 0.617
morphogenesis of embryonic epithelium GO:0016331 159 0.586
Mouse
forebrain development GO:0030900 302 0.580
Mouse
blood vessel morphogenesis GO:0048514 285 0.554
Mouse
developmental maturation GO:0021700 193 0.552
Mouse
embryonic skeletal system development GO:0048706 120 0.549
Mouse
urogenital system development GO:0001655 261 0.531
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.494
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.487
neural tube development GO:0021915 160 0.485
stem cell differentiation GO:0048863 268 0.473
Mouse
cellular amino acid metabolic process GO:0006520 103 0.460
striated muscle tissue development GO:0014706 293 0.451
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.420
Mouse
skeletal system development GO:0001501 356 0.416
Mouse
stem cell proliferation GO:0072089 117 0.403
Mouse
cartilage development GO:0051216 140 0.403
Mouse
negative regulation of nervous system development GO:0051961 156 0.395
Mouse
negative regulation of cell development GO:0010721 169 0.394
Mouse
cell adhesion GO:0007155 329 0.393
regulation of stem cell proliferation GO:0072091 78 0.392
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.389
Mouse
non canonical wnt signaling pathway GO:0035567 33 0.376
central nervous system neuron differentiation GO:0021953 162 0.373
heart morphogenesis GO:0003007 178 0.370
Mouse
neural tube formation GO:0001841 108 0.367
renal tubule development GO:0061326 87 0.365
Mouse
respiratory tube development GO:0030323 167 0.362
nephron epithelium development GO:0072009 92 0.357
Mouse
neural tube closure GO:0001843 90 0.349
skin development GO:0043588 220 0.348
stem cell development GO:0048864 219 0.345
Mouse
nephron tubule morphogenesis GO:0072078 68 0.338
Mouse
positive regulation of nervous system development GO:0051962 221 0.335
cell fate commitment GO:0045165 210 0.327
Mouse Worm
inner ear morphogenesis GO:0042472 101 0.316
Mouse
embryonic epithelial tube formation GO:0001838 130 0.316
Mouse
t cell differentiation GO:0030217 174 0.310
regulation of cellular amino acid metabolic process GO:0006521 5 0.308
wnt signaling pathway GO:0016055 188 0.303
Mouse
retinal blood vessel morphogenesis GO:0061304 3 0.298
actin cytoskeleton organization GO:0030036 220 0.296
Mouse
regulation of ossification GO:0030278 112 0.288
Mouse
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.282
renal tubule morphogenesis GO:0061333 72 0.280
Mouse
leukocyte differentiation GO:0002521 342 0.263
progesterone secretion GO:0042701 1 0.262
mesoderm formation GO:0001707 62 0.261
Mouse Worm
positive regulation of cell development GO:0010720 237 0.259
lymphocyte differentiation GO:0030098 242 0.252
regulation of cellular amine metabolic process GO:0033238 20 0.239
trachea cartilage morphogenesis GO:0060535 4 0.239
ureteric bud development GO:0001657 94 0.235
Mouse
limb development GO:0060173 166 0.231
positive regulation of cell death GO:0010942 224 0.222
cellular amine metabolic process GO:0044106 44 0.205
formation of primary germ layer GO:0001704 77 0.203
Mouse Worm
regulation of cell adhesion GO:0030155 154 0.200
connective tissue development GO:0061448 179 0.194
Mouse Fly
regulation of apoptotic signaling pathway GO:2001233 197 0.193
artery development GO:0060840 53 0.192
Mouse
mesonephric epithelium development GO:0072163 94 0.190
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.190
cochlea morphogenesis GO:0090103 22 0.189
Mouse
epithelial tube formation GO:0072175 130 0.187
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.183
Mouse
muscular septum morphogenesis GO:0003150 4 0.180
aorta development GO:0035904 23 0.179
Mouse
axonogenesis GO:0007409 274 0.178
mesonephros development GO:0001823 97 0.178
Mouse
gland development GO:0048732 330 0.175
Mouse
central nervous system neuron development GO:0021954 67 0.173
pallium development GO:0021543 120 0.172
b cell activation GO:0042113 161 0.171
nephron epithelium morphogenesis GO:0072088 68 0.170
Mouse
ear morphogenesis GO:0042471 118 0.170
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.165
primary neural tube formation GO:0014020 95 0.164
regulation of cellular catabolic process GO:0031329 242 0.163
aortic valve morphogenesis GO:0003180 4 0.163
cellular ketone metabolic process GO:0042180 84 0.162
cellular homeostasis GO:0019725 240 0.160
spermatogenesis GO:0007283 284 0.159
neural tube patterning GO:0021532 43 0.158
regulation of muscle tissue development GO:1901861 97 0.158
Mouse
cell cell signaling involved in mammary gland development GO:0060764 2 0.158
kidney development GO:0001822 213 0.157
Mouse
limbic system development GO:0021761 72 0.156
rho protein signal transduction GO:0007266 32 0.152
aorta morphogenesis GO:0035909 22 0.151
Mouse
tube formation GO:0035148 140 0.149
Mouse
neuron migration GO:0001764 122 0.147
appendage development GO:0048736 166 0.147
mesonephric tubule morphogenesis GO:0072171 63 0.147
Mouse
respiratory system development GO:0060541 190 0.143
Mouse
cation homeostasis GO:0055080 212 0.143
ear development GO:0043583 200 0.142
Mouse
t cell differentiation in thymus GO:0033077 77 0.141
nephron development GO:0072006 109 0.141
Mouse
branching involved in ureteric bud morphogenesis GO:0001658 56 0.139
Mouse
muscle tissue development GO:0060537 308 0.138
Mouse
sensory organ morphogenesis GO:0090596 242 0.137
Mouse
bone mineralization GO:0030282 54 0.137
hippocampus development GO:0021766 52 0.134
embryonic heart tube development GO:0035050 65 0.133
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.133
negative regulation of leukocyte differentiation GO:1902106 51 0.131
regulation of ras gtpase activity GO:0032318 88 0.128
telencephalon development GO:0021537 186 0.127
Mouse
mesoderm development GO:0007498 100 0.126
Mouse Worm Fly
neuron projection guidance GO:0097485 141 0.125
negative regulation of neuron differentiation GO:0045665 101 0.124
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.123
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.122
maintenance of cell number GO:0098727 3 0.121
ras protein signal transduction GO:0007265 77 0.121
regulation of cell projection organization GO:0031344 206 0.121
regulation of nucleotide metabolic process GO:0006140 169 0.121
hindbrain development GO:0030902 128 0.120
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.120
somitogenesis GO:0001756 69 0.119
negative regulation of cell proliferation GO:0008285 296 0.116
gastrulation GO:0007369 116 0.116
Mouse Worm
regulation of secretion by cell GO:1903530 249 0.116
muscle cell differentiation GO:0042692 261 0.116
Mouse Fly
myeloid cell differentiation GO:0030099 233 0.115
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.115
embryonic nail plate morphogenesis GO:0035880 3 0.115
cardiac right atrium morphogenesis GO:0003213 3 0.114
sensory perception GO:0007600 245 0.112
Mouse
metal ion homeostasis GO:0055065 189 0.112
mesoderm morphogenesis GO:0048332 64 0.112
Mouse Worm
regulation of cellular ketone metabolic process GO:0010565 66 0.112
nephron morphogenesis GO:0072028 69 0.111
Mouse
digestive tract morphogenesis GO:0048546 147 0.111
Mouse Worm
cell type specific apoptotic process GO:0097285 268 0.111
Mouse
notch signaling pathway GO:0007219 71 0.111
regulation of neuron differentiation GO:0045664 281 0.111
Mouse
mesonephric tubule development GO:0072164 94 0.110
Mouse
outflow tract morphogenesis GO:0003151 53 0.108
Mouse
mesenchymal cell differentiation GO:0048762 107 0.106
Mouse
thymus development GO:0048538 41 0.106
Mouse
neuroblast differentiation GO:0014016 2 0.105
Mouse
gliogenesis GO:0042063 141 0.104
embryonic heart tube morphogenesis GO:0003143 51 0.103
myoblast differentiation GO:0045445 52 0.102
epidermis development GO:0008544 187 0.102
central nervous system vasculogenesis GO:0022009 3 0.101
regulation of hydrolase activity GO:0051336 246 0.101
renal system development GO:0072001 225 0.101
Mouse
regulation of epithelial to mesenchymal transition GO:0010717 22 0.100
negative regulation of neuron projection development GO:0010977 50 0.099
regulation of neuron projection development GO:0010975 169 0.098
cardiac ventricle development GO:0003231 83 0.098
nephric duct formation GO:0072179 4 0.098
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.097
Mouse
regulation of tight junction assembly GO:2000810 2 0.097
regulation of rho gtpase activity GO:0032319 58 0.096
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.096
skeletal muscle organ development GO:0060538 163 0.096
Mouse
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.096
determination of left right symmetry GO:0007368 80 0.095
amine metabolic process GO:0009308 45 0.095
vascular smooth muscle cell differentiation GO:0035886 11 0.094
positive regulation of apoptotic process GO:0043065 217 0.094
embryonic digit morphogenesis GO:0042733 56 0.093
regulation of homeostatic process GO:0032844 182 0.092
mesonephric duct morphogenesis GO:0072180 4 0.092
regulation of neuron death GO:1901214 134 0.091
Mouse
regulation of reproductive process GO:2000241 66 0.091
regulation of cartilage development GO:0061035 44 0.090
Mouse
positive regulation of neuroblast proliferation GO:0002052 19 0.090
glial cell differentiation GO:0010001 131 0.090
cardiac chamber development GO:0003205 108 0.090
thymic t cell selection GO:0045061 22 0.090
cerebellum vasculature development GO:0061300 1 0.090
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.089
tongue development GO:0043586 18 0.089
Mouse
ureteric bud morphogenesis GO:0060675 62 0.089
Mouse
appendage morphogenesis GO:0035107 149 0.089
embryonic limb morphogenesis GO:0030326 126 0.089
forebrain neuron differentiation GO:0021879 52 0.088
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.088
bone development GO:0060348 120 0.088
mesenchyme development GO:0060485 152 0.087
Mouse
regulation of cellular response to stress GO:0080135 159 0.087
regulation of bmp signaling pathway GO:0030510 60 0.086
muscle system process GO:0003012 141 0.086
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.086
regulation of system process GO:0044057 200 0.086
regulation of protein transport GO:0051223 163 0.084
neural precursor cell proliferation GO:0061351 121 0.084
Mouse
astrocyte differentiation GO:0048708 43 0.084
parathyroid hormone secretion GO:0035898 2 0.083
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.083
bone morphogenesis GO:0060349 78 0.083
megakaryocyte differentiation GO:0030219 26 0.082
regulation of wnt signaling pathway GO:0030111 123 0.082
Mouse
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.082
negative regulation of hepatocyte differentiation GO:0070367 1 0.081
multicellular organismal homeostasis GO:0048871 164 0.081
negative regulation of mitotic cell cycle embryonic GO:0045976 2 0.081
cardiac muscle tissue development GO:0048738 130 0.081
angiogenesis GO:0001525 201 0.080
cranial nerve development GO:0021545 41 0.080
Mouse
sympathetic nervous system development GO:0048485 22 0.080
regulation of secretion GO:0051046 274 0.079
lung morphogenesis GO:0060425 50 0.078
skeletal muscle cell differentiation GO:0035914 66 0.078
Mouse
homeostasis of number of cells GO:0048872 210 0.078
cell migration involved in endocardial cushion formation GO:0003273 3 0.078
camera type eye development GO:0043010 266 0.076
locomotory behavior GO:0007626 195 0.076
clara cell differentiation GO:0060486 4 0.075
positive regulation of protein modification process GO:0031401 299 0.075
regulation of establishment of planar polarity GO:0090175 28 0.075
organelle fission GO:0048285 170 0.075
negative regulation of immune system process GO:0002683 209 0.075
wound healing GO:0042060 157 0.074
apoptotic signaling pathway GO:0097190 306 0.074
organophosphate catabolic process GO:0046434 232 0.074
ossification GO:0001503 216 0.074
Mouse
forebrain neuron development GO:0021884 30 0.074
spinal cord ventral commissure morphogenesis GO:0021965 2 0.074
establishment or maintenance of cell polarity GO:0007163 86 0.074
bmp signaling pathway GO:0030509 93 0.074
central nervous system neuron axonogenesis GO:0021955 28 0.073
peptidyl amino acid modification GO:0018193 336 0.071
central nervous system projection neuron axonogenesis GO:0021952 21 0.071
tissue homeostasis GO:0001894 115 0.071
b cell differentiation GO:0030183 78 0.070
metencephalon development GO:0022037 89 0.070
positive regulation of kinase activity GO:0033674 155 0.070
histone modification GO:0016570 159 0.070
nucleoside triphosphate catabolic process GO:0009143 205 0.070
renal vesicle induction GO:0072034 3 0.069
rac protein signal transduction GO:0016601 13 0.069
forebrain generation of neurons GO:0021872 63 0.069
cardiac right ventricle formation GO:0003219 3 0.068
regulation of embryonic development GO:0045995 71 0.068
Mouse
compound eye development GO:0048749 1 0.068
spinal cord development GO:0021510 81 0.067
retina development in camera type eye GO:0060041 119 0.067
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.067
mitral valve development GO:0003174 4 0.066
asymmetric stem cell division GO:0098722 3 0.066
cerebral cortex development GO:0021987 86 0.065
purine ribonucleotide metabolic process GO:0009150 290 0.065
hormone secretion GO:0046879 128 0.065
cell maturation GO:0048469 127 0.065
Mouse
positive regulation of programmed cell death GO:0043068 218 0.065
regulation of neuron apoptotic process GO:0043523 122 0.064
Mouse
prostate gland development GO:0030850 48 0.064
determination of heart left right asymmetry GO:0061371 48 0.064
axon guidance GO:0007411 141 0.064
female sex determination GO:0030237 1 0.063
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.063
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.062
apical junction assembly GO:0043297 15 0.062
positive regulation of neuron differentiation GO:0045666 141 0.062
positive regulation of stem cell proliferation GO:2000648 59 0.061
Mouse
negative regulation of myeloid cell differentiation GO:0045638 38 0.061
cardiac ventricle morphogenesis GO:0003208 50 0.061
macromolecule catabolic process GO:0009057 281 0.060
regulation of gtp catabolic process GO:0033124 113 0.060
endochondral bone morphogenesis GO:0060350 50 0.060
developmental programmed cell death GO:0010623 41 0.060
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.060
hematopoietic progenitor cell differentiation GO:0002244 143 0.060
regulation of nucleotide catabolic process GO:0030811 122 0.060
cytoplasmic transport GO:0016482 234 0.059
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.059
inner ear receptor cell differentiation GO:0060113 61 0.059
anatomical structure homeostasis GO:0060249 145 0.059
olfactory bulb development GO:0021772 30 0.059
ameboidal type cell migration GO:0001667 128 0.059
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.059
platelet morphogenesis GO:0036344 13 0.058
erythrocyte differentiation GO:0030218 88 0.058
cerebellum vasculature morphogenesis GO:0061301 1 0.058
organonitrogen compound catabolic process GO:1901565 264 0.058
cell division GO:0051301 120 0.057
palate development GO:0060021 76 0.057
hindbrain formation GO:0021576 1 0.057
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.057
cerebellum development GO:0021549 77 0.057
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.056
chemotaxis GO:0006935 247 0.056
ribonucleoside triphosphate metabolic process GO:0009199 220 0.056
stem cell maintenance GO:0019827 130 0.055
Mouse
positive regulation of homeostatic process GO:0032846 64 0.055
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.055
regulation of protein targeting GO:1903533 61 0.055
wnt signaling pathway involved in kidney development GO:0061289 2 0.054
regulation of rac gtpase activity GO:0032314 13 0.054
establishment of planar polarity GO:0001736 28 0.053
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 7 0.053
skeletal muscle fiber development GO:0048741 58 0.053
negative regulation of execution phase of apoptosis GO:1900118 4 0.053
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.053
multi multicellular organism process GO:0044706 109 0.052
organonitrogen compound biosynthetic process GO:1901566 192 0.052
regulation of chorionic trophoblast cell proliferation GO:1901382 1 0.052
negative regulation of bmp signaling pathway GO:0030514 35 0.052
protein import into nucleus GO:0006606 95 0.052
Mouse
neuron death GO:0070997 154 0.052
Mouse
mammary gland epithelium development GO:0061180 65 0.051
mitotic cell cycle GO:0000278 195 0.050
cellular chemical homeostasis GO:0055082 215 0.050
regulation of stem cell maintenance GO:2000036 17 0.050
gtp catabolic process GO:0006184 143 0.050
positive regulation of stem cell differentiation GO:2000738 23 0.050
limb morphogenesis GO:0035108 149 0.050
canonical wnt signaling pathway GO:0060070 130 0.049
tube closure GO:0060606 91 0.049
cochlea development GO:0090102 35 0.048
Mouse
nucleoside metabolic process GO:0009116 246 0.048
negative regulation of neuron projection regeneration GO:0070571 3 0.048
regulation of establishment of protein localization GO:0070201 181 0.048
lateral inhibition GO:0046331 1 0.047
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.047
Mouse
bronchus development GO:0060433 10 0.047
mechanoreceptor differentiation GO:0042490 67 0.047
regulation of lymphocyte differentiation GO:0045619 107 0.047
negative regulation of apoptotic signaling pathway GO:2001234 104 0.047
learning or memory GO:0007611 148 0.047
regulation of ras protein signal transduction GO:0046578 114 0.047
neural crest cell differentiation GO:0014033 54 0.046
ribonucleoside metabolic process GO:0009119 245 0.046
actin filament bundle assembly GO:0051017 40 0.046
cardiac epithelial to mesenchymal transition GO:0060317 18 0.046
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.046
asymmetric neuroblast division GO:0055059 1 0.045
t cell activation GO:0042110 289 0.045
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.045
oligodendrocyte differentiation GO:0048709 53 0.045
renal outer medulla development GO:0072054 2 0.045
negative regulation of catenin import into nucleus GO:0035414 2 0.045
hematopoietic stem cell differentiation GO:0060218 8 0.045
cellular response to hormone stimulus GO:0032870 150 0.044
establishment of organ orientation GO:0048561 1 0.044
positive regulation of dna templated transcription initiation GO:2000144 5 0.044
blood circulation GO:0008015 195 0.044
syncytiotrophoblast cell differentiation involved in labyrinthine layer development GO:0060715 2 0.044
cardiocyte differentiation GO:0035051 87 0.044
cell cycle g2 m phase transition GO:0044839 20 0.044
regulation of cellular component biogenesis GO:0044087 181 0.044
Mouse
regulation of ovulation GO:0060278 3 0.044
digestive system development GO:0055123 200 0.043
Mouse Worm
regulation of cell activation GO:0050865 289 0.043
sensory perception of mechanical stimulus GO:0050954 107 0.043
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.043
regionalization GO:0003002 337 0.043
Mouse
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.043
kidney morphogenesis GO:0060993 83 0.043
Mouse
cell fate specification GO:0001708 72 0.042
Mouse Worm
commissural neuron axon guidance GO:0071679 8 0.042
glomerular mesangial cell development GO:0072144 3 0.042
regulation of protein localization GO:0032880 231 0.042
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.042
guanosine containing compound metabolic process GO:1901068 144 0.041
lung field specification GO:0060424 3 0.041
stem cell division GO:0017145 30 0.041
positive regulation of gtpase activity GO:0043547 85 0.041
response to organonitrogen compound GO:0010243 246 0.041
astrocyte fate commitment GO:0060018 4 0.040
mesonephric duct formation GO:0072181 2 0.040
purine ribonucleoside metabolic process GO:0046128 241 0.040
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.040
t cell selection GO:0045058 34 0.040
peptide secretion GO:0002790 114 0.040
bone marrow development GO:0048539 3 0.040
regulation of cardioblast differentiation GO:0051890 3 0.040
lymphocyte activation involved in immune response GO:0002285 93 0.040
glandular epithelial cell differentiation GO:0002067 38 0.040
regulation of retina development in camera type eye GO:1902866 3 0.039
Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.039
sequestering of metal ion GO:0051238 19 0.039
compartment pattern specification GO:0007386 4 0.039
lung cell differentiation GO:0060479 30 0.039
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.039
cell cell signaling involved in cell fate commitment GO:0045168 35 0.039
Mouse
immune effector process GO:0002252 321 0.039
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.039
sensory perception of sound GO:0007605 97 0.039
Mouse
peptide transport GO:0015833 133 0.039
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.039
mesonephric tubule formation GO:0072172 11 0.039
Mouse
purine nucleoside metabolic process GO:0042278 241 0.039
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.039
positive regulation of hydrolase activity GO:0051345 148 0.039
negative regulation of glial cell proliferation GO:0060253 4 0.038
cerebellar cortex development GO:0021695 48 0.038
positive regulation of mesonephros development GO:0061213 20 0.038
Mouse
cell substrate adhesion GO:0031589 130 0.038
fasciculation of motor neuron axon GO:0097156 2 0.038
forebrain regionalization GO:0021871 25 0.038
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.037
myotube differentiation GO:0014902 105 0.037
Mouse Fly
cellular response to organonitrogen compound GO:0071417 145 0.037
hypophysis morphogenesis GO:0048850 3 0.037
carbohydrate homeostasis GO:0033500 128 0.037
regulation of intracellular protein transport GO:0033157 82 0.037
development of primary sexual characteristics GO:0045137 143 0.037
Mouse Fly
mitotic cell cycle process GO:1903047 159 0.037
peptidyl tyrosine modification GO:0018212 145 0.037
meiotic cell cycle GO:0051321 122 0.037
blood coagulation GO:0007596 76 0.037
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.036
endocardial cell differentiation GO:0060956 4 0.036
cell differentiation in spinal cord GO:0021515 53 0.036
ventral midline development GO:0007418 4 0.036
head morphogenesis GO:0060323 34 0.036
midbrain hindbrain boundary maturation GO:0021732 1 0.036
cell aging GO:0007569 35 0.036
macromolecule methylation GO:0043414 120 0.036
apoptotic process involved in morphogenesis GO:0060561 25 0.035
cellular response to lipid GO:0071396 145 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.035
regulation of myeloid leukocyte differentiation GO:0002761 58 0.035
regulation of protein serine threonine kinase activity GO:0071900 157 0.035
platelet formation GO:0030220 12 0.035
regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000702 1 0.035
positive regulation of neuron apoptotic process GO:0043525 25 0.035
skin morphogenesis GO:0043589 38 0.035
mesenchymal cell development GO:0014031 93 0.035
regulation of cell fate commitment GO:0010453 19 0.035
embryonic placenta development GO:0001892 98 0.035
multicellular organismal reproductive behavior GO:0033057 23 0.035
cardiac septum morphogenesis GO:0060411 46 0.035
response to growth factor GO:0070848 198 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.034
cardiac septum development GO:0003279 59 0.034
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.034
coagulation GO:0050817 78 0.034
methylation GO:0032259 134 0.034
cytokine production GO:0001816 319 0.034
hindbrain morphogenesis GO:0021575 46 0.034
cation transmembrane transport GO:0098655 266 0.034
platelet activation GO:0030168 40 0.033
protein localization to nucleus GO:0034504 121 0.033
Mouse
regulation of protein import into nucleus GO:0042306 52 0.033
calcium ion homeostasis GO:0055074 127 0.033
polarity specification of proximal distal axis GO:0010085 2 0.033
positive regulation of protein kinase activity GO:0045860 144 0.033
negative regulation of fat cell differentiation GO:0045599 36 0.033
morphogenesis of a polarized epithelium GO:0001738 37 0.033
blastocyst formation GO:0001825 33 0.032
regulation of endopeptidase activity GO:0052548 89 0.032
cardiac muscle cell myoblast differentiation GO:0060379 8 0.032
nephron tubule development GO:0072080 84 0.032
Mouse
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.032
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.032
positive regulation of protein transport GO:0051222 93 0.032
regulation of osteoblast differentiation GO:0045667 67 0.032
synapse organization GO:0050808 125 0.032
Mouse
coronary vasculature development GO:0060976 12 0.032
purine ribonucleotide catabolic process GO:0009154 208 0.032
arterial endothelial cell differentiation GO:0060842 5 0.031
muscle cell fate specification GO:0042694 1 0.031
positive regulation of cellular catabolic process GO:0031331 148 0.031
protein modification by small protein conjugation or removal GO:0070647 207 0.031
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.031
definitive hemopoiesis GO:0060216 20 0.031
regulation of cell cycle process GO:0010564 160 0.031
Mouse
regulation of binding GO:0051098 111 0.031
epithelial cell proliferation GO:0050673 174 0.031
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.031
cell cell junction assembly GO:0007043 27 0.031
glucose homeostasis GO:0042593 128 0.031
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.031
inner ear receptor cell development GO:0060119 39 0.030
cellular ion homeostasis GO:0006873 165 0.030
hemostasis GO:0007599 78 0.030
axis elongation involved in somitogenesis GO:0090245 4 0.030
modification dependent macromolecule catabolic process GO:0043632 133 0.030
regulation of proteolysis GO:0030162 164 0.030
elastic fiber assembly GO:0048251 4 0.030
negative regulation of cartilage development GO:0061037 17 0.030
cellular metal ion homeostasis GO:0006875 151 0.030
cerebellum morphogenesis GO:0021587 42 0.030
leukocyte activation involved in immune response GO:0002366 126 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.030
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.030
regulation of hormone secretion GO:0046883 88 0.030
myeloid cell homeostasis GO:0002262 114 0.030
transcription initiation from rna polymerase ii promoter GO:0006367 8 0.030
dna replication GO:0006260 52 0.030
regulation of epithelial cell proliferation GO:0050678 141 0.029
Mouse

Six5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.053
disease of anatomical entity DOID:7 0 0.046
musculoskeletal system disease DOID:17 0 0.046