Mus musculus

82 known processes

Esx1

extraembryonic, spermatogenesis, homeobox 1

(Aliases: Spx1)

Esx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 337 0.690
Zebrafish Mouse
labyrinthine layer blood vessel development GO:0060716 21 0.610
endocrine system development GO:0035270 98 0.602
Mouse
cell fate commitment GO:0045165 210 0.598
forebrain development GO:0030900 302 0.568
Zebrafish Mouse
axon guidance GO:0007411 141 0.545
regulation of cellular amine metabolic process GO:0033238 20 0.511
epithelial tube morphogenesis GO:0060562 303 0.502
stem cell differentiation GO:0048863 268 0.489
stem cell development GO:0048864 219 0.465
regulation of cellular amino acid metabolic process GO:0006521 5 0.461
leukocyte differentiation GO:0002521 342 0.460
amine metabolic process GO:0009308 45 0.453
labyrinthine layer development GO:0060711 49 0.443
telencephalon development GO:0021537 186 0.417
regulation of cell motility GO:2000145 236 0.413
Zebrafish
chemotaxis GO:0006935 247 0.404
stem cell maintenance GO:0019827 130 0.396
positive regulation of nervous system development GO:0051962 221 0.396
striated muscle tissue development GO:0014706 293 0.395
regulation of glial cell differentiation GO:0045685 41 0.364
skin development GO:0043588 220 0.361
cellular amino acid metabolic process GO:0006520 103 0.360
blood vessel morphogenesis GO:0048514 285 0.353
embryonic placenta development GO:0001892 98 0.344
appendage development GO:0048736 166 0.340
Mouse
ear development GO:0043583 200 0.337
adaptive immune response GO:0002250 155 0.322
axonogenesis GO:0007409 274 0.310
positive regulation of cell development GO:0010720 237 0.301
positive regulation of stem cell proliferation GO:2000648 59 0.298
glycerolipid metabolic process GO:0046486 122 0.295
cellular ketone metabolic process GO:0042180 84 0.291
somatotropin secreting cell differentiation GO:0060126 4 0.287
Mouse
placenta development GO:0001890 140 0.282
branching morphogenesis of an epithelial tube GO:0048754 159 0.281
regulation of gliogenesis GO:0014013 50 0.271
morphogenesis of a branching epithelium GO:0061138 193 0.271
cellular amine metabolic process GO:0044106 44 0.265
gland development GO:0048732 330 0.261
Mouse
neuron projection guidance GO:0097485 141 0.260
telencephalon cell migration GO:0022029 55 0.259
phospholipid metabolic process GO:0006644 87 0.253
embryonic organ morphogenesis GO:0048562 276 0.251
ameboidal type cell migration GO:0001667 128 0.248
heart morphogenesis GO:0003007 178 0.243
epidermis development GO:0008544 187 0.240
limbic system development GO:0021761 72 0.233
Mouse
placenta blood vessel development GO:0060674 31 0.232
camera type eye development GO:0043010 266 0.231
Mouse
odontogenesis GO:0042476 78 0.225
germ cell development GO:0007281 185 0.222
Mouse
skeletal muscle organ development GO:0060538 163 0.212
mesoderm formation GO:0001707 62 0.204
limb development GO:0060173 166 0.202
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.197
positive regulation of cellular amine metabolic process GO:0033240 5 0.196
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.196
muscle tissue development GO:0060537 308 0.191
appendage morphogenesis GO:0035107 149 0.190
pallium development GO:0021543 120 0.189
skeletal system development GO:0001501 356 0.186
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.184
carbohydrate metabolic process GO:0005975 230 0.184
regulation of organ morphogenesis GO:2000027 144 0.179
spermatogenesis GO:0007283 284 0.178
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.177
neuron migration GO:0001764 122 0.176
carbohydrate derivative biosynthetic process GO:1901137 183 0.170
positive regulation of programmed cell death GO:0043068 218 0.169
syncytium formation GO:0006949 43 0.163
chromatin organization GO:0006325 206 0.163
neural tube development GO:0021915 160 0.162
sensory organ morphogenesis GO:0090596 242 0.162
cell fate specification GO:0001708 72 0.160
regulation of cellular ketone metabolic process GO:0010565 66 0.160
gliogenesis GO:0042063 141 0.160
positive regulation of transcription via serum response element binding GO:0010735 1 0.154
ventral spinal cord interneuron fate commitment GO:0060579 14 0.153
inner ear morphogenesis GO:0042472 101 0.153
pancreatic pp cell fate commitment GO:0003329 2 0.148
cellular calcium ion homeostasis GO:0006874 119 0.148
epithelial cell proliferation GO:0050673 174 0.147
morphogenesis of a branching structure GO:0001763 203 0.145
negative regulation of protein metabolic process GO:0051248 282 0.145
metal ion homeostasis GO:0055065 189 0.144
segmentation GO:0035282 93 0.144
Zebrafish
cellular divalent inorganic cation homeostasis GO:0072503 127 0.140
forebrain generation of neurons GO:0021872 63 0.139
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.138
cardiac chamber morphogenesis GO:0003206 93 0.137
cellular lipid metabolic process GO:0044255 323 0.137
Mouse
striated muscle cell development GO:0055002 125 0.136
cerebral cortex cell migration GO:0021795 44 0.136
cell fate determination GO:0001709 32 0.134
stem cell proliferation GO:0072089 117 0.131
skeletal system morphogenesis GO:0048705 203 0.130
peptidyl amino acid modification GO:0018193 336 0.130
forebrain neuron differentiation GO:0021879 52 0.127
ectoderm formation GO:0001705 3 0.127
negative regulation of cellular amine metabolic process GO:0033239 1 0.123
cell maturation GO:0048469 127 0.122
multicellular organismal response to stress GO:0033555 62 0.121
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.119
syncytium formation by plasma membrane fusion GO:0000768 42 0.118
ear morphogenesis GO:0042471 118 0.117
locomotory behavior GO:0007626 195 0.117
cardiac ventricle development GO:0003231 83 0.117
regulation of homeostatic process GO:0032844 182 0.116
digestive system development GO:0055123 200 0.115
forebrain cell migration GO:0021885 58 0.115
macromolecule catabolic process GO:0009057 281 0.113
tube closure GO:0060606 91 0.112
small molecule biosynthetic process GO:0044283 132 0.111
regulation of stem cell proliferation GO:0072091 78 0.110
myeloid cell differentiation GO:0030099 233 0.108
cell type specific apoptotic process GO:0097285 268 0.107
muscle tissue morphogenesis GO:0060415 53 0.106
response to radiation GO:0009314 165 0.105
myeloid leukocyte differentiation GO:0002573 119 0.105
peptidyl tyrosine phosphorylation GO:0018108 143 0.104
bmp signaling pathway GO:0030509 93 0.104
mesoderm morphogenesis GO:0048332 64 0.102
regulation of angiogenesis GO:0045765 81 0.102
development of primary male sexual characteristics GO:0046546 88 0.102
cardiac chamber development GO:0003205 108 0.101
male sex differentiation GO:0046661 109 0.101
regulation of neuron differentiation GO:0045664 281 0.101
digestive tract development GO:0048565 190 0.100
cellular chemical homeostasis GO:0055082 215 0.100
formation of primary germ layer GO:0001704 77 0.099
neuroepithelial cell differentiation GO:0060563 37 0.099
establishment of glial blood brain barrier GO:0060857 2 0.096
inflammatory response GO:0006954 244 0.096
positive regulation of glial cell differentiation GO:0045687 21 0.096
lymphocyte differentiation GO:0030098 242 0.095
neuronal action potential GO:0019228 54 0.095
ossification GO:0001503 216 0.095
glial cell development GO:0021782 54 0.094
artery development GO:0060840 53 0.094
glial cell differentiation GO:0010001 131 0.093
cation transport GO:0006812 399 0.091
neuron fate specification GO:0048665 30 0.091
regulation of cell projection organization GO:0031344 206 0.091
hexose metabolic process GO:0019318 98 0.090
peptidyl tyrosine modification GO:0018212 145 0.090
spermatid development GO:0007286 108 0.090
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.089
response to organic cyclic compound GO:0014070 198 0.089
regulation of epithelial cell proliferation GO:0050678 141 0.089
negative regulation of cellular protein metabolic process GO:0032269 247 0.088
spermatid differentiation GO:0048515 115 0.088
calcium ion homeostasis GO:0055074 127 0.088
heart trabecula formation GO:0060347 14 0.086
cerebral cortex development GO:0021987 86 0.086
endothelial cell migration GO:0043542 44 0.086
gonad development GO:0008406 141 0.086
respiratory system development GO:0060541 190 0.085
negative regulation of cellular component organization GO:0051129 194 0.085
regulation of bmp signaling pathway GO:0030510 60 0.083
cardiac muscle tissue development GO:0048738 130 0.083
spinal cord patterning GO:0021511 25 0.083
cellular homeostasis GO:0019725 240 0.082
muscle cell development GO:0055001 133 0.082
mesenchyme development GO:0060485 152 0.082
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.081
positive regulation of cell motility GO:2000147 116 0.080
Zebrafish
negative regulation of cell activation GO:0050866 111 0.080
regulation of system process GO:0044057 200 0.079
regulation of histone modification GO:0031056 56 0.079
epithelium migration GO:0090132 63 0.078
multicellular organismal signaling GO:0035637 91 0.078
respiratory tube development GO:0030323 167 0.077
cation homeostasis GO:0055080 212 0.076
ventricular cardiac myofibril assembly GO:0055005 3 0.076
pancreatic a cell fate commitment GO:0003326 2 0.075
cardiac pacemaker cell fate commitment GO:0060927 1 0.075
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.075
cardiac ventricle morphogenesis GO:0003208 50 0.075
developmental maturation GO:0021700 193 0.075
regulation of microvillus assembly GO:0032534 3 0.074
muscle cell differentiation GO:0042692 261 0.073
regulation of cell migration GO:0030334 219 0.073
Zebrafish
morphogenesis of embryonic epithelium GO:0016331 159 0.072
chromatin modification GO:0016568 187 0.072
atrial cardiac muscle cell development GO:0055014 2 0.072
positive regulation of cell cycle GO:0045787 92 0.072
regulation of cell cycle GO:0051726 281 0.071
Human
cardiocyte differentiation GO:0035051 87 0.071
positive regulation of cell division GO:0051781 31 0.071
nuclear division GO:0000280 158 0.070
primary neural tube formation GO:0014020 95 0.070
neural precursor cell proliferation GO:0061351 121 0.070
covalent chromatin modification GO:0016569 163 0.069
trophectodermal cell differentiation GO:0001829 21 0.069
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.069
nerve development GO:0021675 67 0.069
myelination GO:0042552 74 0.069
mitotic cell cycle process GO:1903047 159 0.068
dna metabolic process GO:0006259 303 0.068
urogenital system development GO:0001655 261 0.068
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.068
purkinje myocyte differentiation GO:0003168 1 0.068
cellular carbohydrate metabolic process GO:0044262 119 0.067
negative regulation of cell proliferation GO:0008285 296 0.066
regulation of apoptotic signaling pathway GO:2001233 197 0.066
notch signaling pathway GO:0007219 71 0.066
cell chemotaxis GO:0060326 81 0.065
sequestering of metal ion GO:0051238 19 0.065
negative regulation of cell development GO:0010721 169 0.065
metanephros development GO:0001656 79 0.065
ensheathment of neurons GO:0007272 76 0.064
angiogenesis GO:0001525 201 0.063
response to acid chemical GO:0001101 111 0.063
type b pancreatic cell fate commitment GO:0003327 1 0.063
cellular response to growth factor stimulus GO:0071363 197 0.063
spleen development GO:0048536 39 0.063
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.062
mammary gland duct morphogenesis GO:0060603 38 0.062
regulation of neuron projection development GO:0010975 169 0.062
maintenance of location GO:0051235 89 0.062
paraxial mesodermal cell differentiation GO:0048342 2 0.062
cell adhesion GO:0007155 329 0.061
regulation of organelle organization GO:0033043 289 0.061
nephron epithelium development GO:0072009 92 0.061
sprouting angiogenesis GO:0002040 26 0.061
regulation of mitotic cell cycle GO:0007346 126 0.061
neuroblast proliferation GO:0007405 49 0.061
oxidation reduction process GO:0055114 342 0.061
smoothened signaling pathway GO:0007224 105 0.061
male gonad development GO:0008584 88 0.060
embryonic skeletal system development GO:0048706 120 0.060
positive regulation of organelle organization GO:0010638 128 0.060
pancreatic pp cell differentiation GO:0003312 2 0.060
atrioventricular node cell development GO:0060928 2 0.060
cellular metal ion homeostasis GO:0006875 151 0.059
regulation of muscle tissue development GO:1901861 97 0.058
outflow tract morphogenesis GO:0003151 53 0.058
positive regulation of neural precursor cell proliferation GO:2000179 42 0.058
regulation of neuron death GO:1901214 134 0.058
hindbrain development GO:0030902 128 0.058
immune effector process GO:0002252 321 0.057
spinal cord dorsal ventral patterning GO:0021513 23 0.057
cell growth GO:0016049 130 0.056
regulation of microvillus organization GO:0032530 3 0.056
organelle fission GO:0048285 170 0.055
embryonic epithelial tube formation GO:0001838 130 0.055
axon ensheathment GO:0008366 76 0.055
paraxial mesodermal cell fate commitment GO:0048343 2 0.055
atrial cardiac muscle cell differentiation GO:0055011 2 0.054
central nervous system neuron differentiation GO:0021953 162 0.054
mesoderm development GO:0007498 100 0.054
metencephalon development GO:0022037 89 0.054
negative regulation of nervous system development GO:0051961 156 0.053
development of primary female sexual characteristics GO:0046545 73 0.053
odontogenesis of dentin containing tooth GO:0042475 66 0.052
tissue migration GO:0090130 68 0.052
mesonephric epithelium development GO:0072163 94 0.052
mechanoreceptor differentiation GO:0042490 67 0.052
negative regulation of neuron apoptotic process GO:0043524 92 0.052
nephron development GO:0072006 109 0.051
neurohypophysis development GO:0021985 2 0.051
diencephalon development GO:0021536 63 0.051
Mouse
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.051
mesodermal cell differentiation GO:0048333 22 0.051
epithelial cell development GO:0002064 159 0.051
auditory receptor cell differentiation GO:0042491 37 0.051
cartilage development GO:0051216 140 0.051
response to growth factor GO:0070848 198 0.051
regulation of ion homeostasis GO:2000021 64 0.050
endomembrane system organization GO:0010256 147 0.050
ventricular septum development GO:0003281 42 0.050
cardiac muscle tissue morphogenesis GO:0055008 44 0.050
positive regulation of protein modification process GO:0031401 299 0.050
cardiac cell fate determination GO:0060913 2 0.050
regulation of chromosome organization GO:0033044 83 0.050
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.050
regulation of transmembrane transport GO:0034762 128 0.049
digestive tract morphogenesis GO:0048546 147 0.049
negative regulation of epithelial cell proliferation GO:0050680 64 0.049
renal system development GO:0072001 225 0.049
auditory receptor cell fate specification GO:0042667 1 0.049
lung development GO:0030324 164 0.049
leydig cell differentiation GO:0033327 10 0.048
renal tubule morphogenesis GO:0061333 72 0.048
regulation of vasculature development GO:1901342 88 0.048
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.047
regulation of timing of cell differentiation GO:0048505 11 0.047
brain segmentation GO:0035284 3 0.047
steroid metabolic process GO:0008202 119 0.047
embryonic limb morphogenesis GO:0030326 126 0.047
regulation of neuroblast proliferation GO:1902692 27 0.046
mitotic cell cycle GO:0000278 195 0.046
motor neuron axon guidance GO:0008045 26 0.046
cardiac muscle cell development GO:0055013 39 0.046
metanephric nephron development GO:0072210 34 0.046
meiotic cell cycle GO:0051321 122 0.046
cell differentiation in spinal cord GO:0021515 53 0.046
cytoplasmic transport GO:0016482 234 0.045
regulation of leukocyte differentiation GO:1902105 159 0.045
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.045
synaptic transmission GO:0007268 329 0.045
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.045
multicellular organism growth GO:0035264 161 0.044
blastocyst development GO:0001824 80 0.044
regulation of muscle cell apoptotic process GO:0010660 17 0.044
nephron tubule development GO:0072080 84 0.044
glial cell fate commitment GO:0021781 14 0.044
glucose metabolic process GO:0006006 92 0.044
tissue remodeling GO:0048771 102 0.044
jak stat cascade GO:0007259 42 0.044
dendrite development GO:0016358 115 0.044
divalent metal ion transport GO:0070838 172 0.044
nephrogenic mesenchyme development GO:0072076 3 0.043
blastocyst formation GO:0001825 33 0.043
skeletal muscle cell differentiation GO:0035914 66 0.043
hemangioblast cell differentiation GO:0060217 1 0.043
embryonic camera type eye development GO:0031076 36 0.043
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.043
paramesonephric duct development GO:0061205 3 0.043
regulation of neuron apoptotic process GO:0043523 122 0.042
transmembrane transport GO:0055085 412 0.042
brain morphogenesis GO:0048854 32 0.042
Mouse
ventral spinal cord interneuron fate determination GO:0060580 1 0.042
generation of precursor metabolites and energy GO:0006091 103 0.042
polarity specification of proximal distal axis GO:0010085 2 0.041
cellular component assembly involved in morphogenesis GO:0010927 139 0.041
organophosphate biosynthetic process GO:0090407 122 0.041
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.041
ventral spinal cord interneuron differentiation GO:0021514 16 0.041
limb morphogenesis GO:0035108 149 0.041
metanephric dct cell differentiation GO:0072240 3 0.041
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.041
cytosolic calcium ion homeostasis GO:0051480 70 0.041
response to transforming growth factor beta GO:0071559 88 0.040
developmental programmed cell death GO:0010623 41 0.040
actin cytoskeleton organization GO:0030036 220 0.040
myeloid cell homeostasis GO:0002262 114 0.040
regulation of organ formation GO:0003156 34 0.040
epithelial tube formation GO:0072175 130 0.040
lens development in camera type eye GO:0002088 62 0.040
cellular ion homeostasis GO:0006873 165 0.040
regulation of cell adhesion GO:0030155 154 0.040
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.040
tube formation GO:0035148 140 0.040
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.040
transmission of nerve impulse GO:0019226 76 0.040
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.040
myeloid cell activation involved in immune response GO:0002275 34 0.039
action potential GO:0001508 78 0.039
positive regulation of angiogenesis GO:0045766 46 0.039
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.039
bundle of his development GO:0003166 4 0.038
connective tissue development GO:0061448 179 0.038
atrioventricular node cell fate commitment GO:0060929 1 0.038
extracellular matrix organization GO:0030198 147 0.038
axial mesodermal cell fate commitment GO:0048322 1 0.038
ion transmembrane transport GO:0034220 361 0.038
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.037
mammary gland morphogenesis GO:0060443 54 0.037
regulation of embryonic development GO:0045995 71 0.037
negative regulation of immune system process GO:0002683 209 0.037
neural tube formation GO:0001841 108 0.037
ventricular cardiac muscle tissue development GO:0003229 38 0.037
midbrain development GO:0030901 35 0.037
positive regulation of protein phosphorylation GO:0001934 242 0.037
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.037
mesodermal cell fate commitment GO:0001710 17 0.037
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.037
organic hydroxy compound metabolic process GO:1901615 203 0.036
meiotic nuclear division GO:0007126 115 0.036
inner ear receptor cell differentiation GO:0060113 61 0.036
negative regulation of secretion by cell GO:1903531 54 0.036
sphingolipid metabolic process GO:0006665 45 0.036
divalent inorganic cation homeostasis GO:0072507 138 0.036
neuron apoptotic process GO:0051402 142 0.036
myotube differentiation GO:0014902 105 0.036
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.036
cell recognition GO:0008037 83 0.036
histone modification GO:0016570 159 0.036
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.035
organelle localization GO:0051640 179 0.035
neural crest cell differentiation GO:0014033 54 0.035
immune response regulating signaling pathway GO:0002764 125 0.035
sensory perception GO:0007600 245 0.035
somitogenesis GO:0001756 69 0.035
Zebrafish
cellular response to antibiotic GO:0071236 4 0.035
regulation of secretion by cell GO:1903530 249 0.035
regulation of membrane potential GO:0042391 192 0.035
regulation of notch signaling pathway GO:0008593 35 0.035
purine nucleotide biosynthetic process GO:0006164 65 0.034
positive regulation of neuroblast proliferation GO:0002052 19 0.034
left lung development GO:0060459 4 0.034
innate immune response GO:0045087 157 0.034
positive regulation of apoptotic process GO:0043065 217 0.034
neuron projection extension GO:1990138 64 0.034
mesenchymal cell differentiation GO:0048762 107 0.034
ventricular cardiac muscle cell development GO:0055015 11 0.034
glycerophospholipid metabolic process GO:0006650 71 0.034
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.034
left right pattern formation GO:0060972 23 0.034
wnt signaling pathway GO:0016055 188 0.034
Mouse
negative regulation of neuron death GO:1901215 98 0.033
metanephric loop of henle development GO:0072236 4 0.033
regulation of cardioblast differentiation GO:0051890 3 0.033
sensory perception of pain GO:0019233 47 0.033
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.033
myelination in peripheral nervous system GO:0022011 19 0.033
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.033
axial mesoderm formation GO:0048320 3 0.033
meiotic cell cycle process GO:1903046 77 0.033
canonical wnt signaling pathway GO:0060070 130 0.033
Mouse
epithelial cell migration GO:0010631 63 0.033
membrane lipid metabolic process GO:0006643 53 0.033
organic acid transport GO:0015849 101 0.033
pulmonary myocardium development GO:0003350 3 0.033
sensory system development GO:0048880 3 0.033
fat cell differentiation GO:0045444 160 0.033
adenohypophysis development GO:0021984 14 0.033
Mouse
ventral spinal cord interneuron specification GO:0021521 11 0.032
lipoprotein metabolic process GO:0042157 43 0.032
osteoclast differentiation GO:0030316 62 0.032
exocrine system development GO:0035272 45 0.032
acylglycerol metabolic process GO:0006639 55 0.032
regulation of exocytosis GO:0017157 61 0.032
embryonic appendage morphogenesis GO:0035113 126 0.032
protein catabolic process GO:0030163 221 0.032
nephric duct formation GO:0072179 4 0.032
positive regulation of growth GO:0045927 104 0.032
foramen ovale closure GO:0035922 1 0.032
regulation of anatomical structure size GO:0090066 178 0.031
regulation of lipid metabolic process GO:0019216 118 0.031
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.031
glycoprotein biosynthetic process GO:0009101 89 0.031
bone morphogenesis GO:0060349 78 0.031
female gonad development GO:0008585 71 0.030
leukocyte activation involved in immune response GO:0002366 126 0.030
clara cell differentiation GO:0060486 4 0.030
fertilization GO:0009566 127 0.030
cardiac muscle cell differentiation GO:0055007 69 0.030
muscle system process GO:0003012 141 0.030
cytokine biosynthetic process GO:0042089 68 0.030
cerebral cortex neuron differentiation GO:0021895 19 0.030
single organismal cell cell adhesion GO:0016337 131 0.030
atrioventricular node cell differentiation GO:0060922 2 0.030
cell fate commitment involved in pattern specification GO:0060581 14 0.030
organelle assembly GO:0070925 177 0.030
positive regulation of cardioblast differentiation GO:0051891 3 0.030
oviduct development GO:0060066 3 0.030
hippocampus development GO:0021766 52 0.029
somatic stem cell maintenance GO:0035019 47 0.029
forebrain neuron development GO:0021884 30 0.029
regulation of hormone levels GO:0010817 211 0.029
lipid biosynthetic process GO:0008610 179 0.029
mesonephros development GO:0001823 97 0.029
positive regulation of immune effector process GO:0002699 107 0.029
his purkinje system development GO:0003164 4 0.029
regulation of cell division GO:0051302 76 0.029
regulation of cartilage development GO:0061035 44 0.029
plasma cell differentiation GO:0002317 3 0.029
regulation of cell cycle process GO:0010564 160 0.029
release of sequestered calcium ion into cytosol GO:0051209 42 0.029
endocytosis GO:0006897 168 0.029
regulation of carbohydrate metabolic process GO:0006109 75 0.028
embryonic placenta morphogenesis GO:0060669 25 0.028
regulation of calcium ion transport GO:0051924 69 0.028
t cell differentiation GO:0030217 174 0.028
branching involved in ureteric bud morphogenesis GO:0001658 56 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.028
embryonic heart tube morphogenesis GO:0003143 51 0.028
regulation of chromatin organization GO:1902275 57 0.028
response to inorganic substance GO:0010035 96 0.027
embryonic heart tube formation GO:0003144 1 0.027
triglyceride metabolic process GO:0006641 51 0.027
positive regulation of cell death GO:0010942 224 0.027
blood vessel endothelial cell migration GO:0043534 23 0.027
monocarboxylic acid metabolic process GO:0032787 191 0.027
regulation of actin cytoskeleton organization GO:0032956 84 0.027
compound eye development GO:0048749 1 0.027
septum transversum development GO:0003343 2 0.027
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.027
hair cell differentiation GO:0035315 40 0.027
regulation of t cell activation GO:0050863 170 0.027
cardiac septum development GO:0003279 59 0.027
single organism cell adhesion GO:0098602 156 0.027
glycoprotein metabolic process GO:0009100 116 0.027
sclerotome development GO:0061056 4 0.027
defense response to other organism GO:0098542 197 0.027
b cell differentiation GO:0030183 78 0.026
lung epithelium development GO:0060428 37 0.026
negative regulation of stem cell maintenance GO:1902455 4 0.026
myeloid leukocyte mediated immunity GO:0002444 42 0.026
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.026
neutral lipid metabolic process GO:0006638 57 0.026

Esx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
musculoskeletal system disease DOID:17 0 0.051
sensory system disease DOID:0050155 0 0.027
nervous system disease DOID:863 0 0.027