Mus musculus

66 known processes

Rad21

RAD21 homolog (S. pombe)

(Aliases: MGC150311,MGC150312,mKIAA0078,SCC1)

Rad21 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular polysaccharide catabolic process GO:0044247 5 0.994
regulation of glycogen catabolic process GO:0005981 2 0.952
regulation of dna endoreduplication GO:0032875 3 0.809
meiotic cell cycle process GO:1903046 77 0.751
Worm
glycogen catabolic process GO:0005980 5 0.715
oxidation reduction process GO:0055114 342 0.648
dna metabolic process GO:0006259 303 0.616
nuclear division GO:0000280 158 0.611
Worm
regulation of cell cycle GO:0051726 281 0.595
polysaccharide catabolic process GO:0000272 5 0.571
meiotic nuclear division GO:0007126 115 0.490
Worm
dna endoreduplication GO:0042023 4 0.467
meiotic chromosome segregation GO:0045132 19 0.401
Worm
generation of precursor metabolites and energy GO:0006091 103 0.398
negative regulation of dna dependent dna replication GO:2000104 1 0.394
male gamete generation GO:0048232 285 0.349
negative regulation of dna replication GO:0008156 4 0.307
apoptotic signaling pathway GO:0097190 306 0.300
glucan catabolic process GO:0009251 5 0.287
regulation of vesicle mediated transport GO:0060627 139 0.282
energy derivation by oxidation of organic compounds GO:0015980 77 0.259
kinetochore organization GO:0051383 2 0.258
glucan metabolic process GO:0044042 32 0.256
regulation of apoptotic signaling pathway GO:2001233 197 0.223
organelle fission GO:0048285 170 0.211
Worm
microtubule based process GO:0007017 236 0.200
microtubule cytoskeleton organization GO:0000226 157 0.187
chromatin modification GO:0016568 187 0.174
dna dependent dna replication GO:0006261 24 0.167
mitotic cell cycle GO:0000278 195 0.163
ras protein signal transduction GO:0007265 77 0.161
regulation of glucose metabolic process GO:0010906 60 0.153
dna replication GO:0006260 52 0.148
protein methylation GO:0006479 81 0.146
negative regulation of cell cycle GO:0045786 123 0.142
chromatin remodeling at centromere GO:0031055 2 0.133
dna conformation change GO:0071103 37 0.131
regulation of cell cycle process GO:0010564 160 0.130
rac protein signal transduction GO:0016601 13 0.118
male meiosis GO:0007140 37 0.117
morphogenesis of embryonic epithelium GO:0016331 159 0.113
cellular carbohydrate metabolic process GO:0044262 119 0.110
cellular carbohydrate catabolic process GO:0044275 15 0.110
energy reserve metabolic process GO:0006112 39 0.109
chromosome organization involved in meiosis GO:0070192 39 0.106
circadian rhythm GO:0007623 114 0.100
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.100
regulation of receptor biosynthetic process GO:0010869 2 0.099
regulation of dna replication GO:0006275 17 0.098
rho protein signal transduction GO:0007266 32 0.097
meiotic cell cycle GO:0051321 122 0.097
Worm
receptor biosynthetic process GO:0032800 3 0.094
endocytosis GO:0006897 168 0.093
sensory perception GO:0007600 245 0.091
gene silencing GO:0016458 38 0.087
chemotaxis GO:0006935 247 0.086
microtubule based movement GO:0007018 84 0.086
male sex differentiation GO:0046661 109 0.084
organelle localization GO:0051640 179 0.083
regulation of rho gtpase activity GO:0032319 58 0.083
dendrite development GO:0016358 115 0.082
cellular polysaccharide metabolic process GO:0044264 38 0.081
mitotic cytokinesis GO:0000281 4 0.078
wnt signaling pathway GO:0016055 188 0.074
intrinsic apoptotic signaling pathway GO:0097193 132 0.074
microtubule nucleation GO:0007020 2 0.073
positive regulation of glycogen catabolic process GO:0045819 2 0.072
cytokinetic process GO:0032506 2 0.072
negative regulation of phosphorus metabolic process GO:0010563 184 0.071
chromosome segregation GO:0007059 48 0.070
Worm
cellular glucan metabolic process GO:0006073 32 0.070
methylation GO:0032259 134 0.070
positive regulation of gtpase activity GO:0043547 85 0.069
respiratory system development GO:0060541 190 0.068
regulation of circadian rhythm GO:0042752 58 0.066
neuron projection guidance GO:0097485 141 0.066
negative regulation of cell cycle process GO:0010948 69 0.065
organelle assembly GO:0070925 177 0.065
stem cell development GO:0048864 219 0.065
monosaccharide metabolic process GO:0005996 106 0.065
maintenance of location GO:0051235 89 0.064
axonogenesis GO:0007409 274 0.064
sister chromatid segregation GO:0000819 20 0.063
endomembrane system organization GO:0010256 147 0.062
negative regulation of cell proliferation GO:0008285 296 0.061
negative regulation of phosphate metabolic process GO:0045936 184 0.061
regulation of carbohydrate catabolic process GO:0043470 12 0.061
cell maturation GO:0048469 127 0.060
histone h3 deacetylation GO:0070932 8 0.060
negative regulation of phagocytosis GO:0050765 4 0.059
digestive tract morphogenesis GO:0048546 147 0.059
regulation of mapk cascade GO:0043408 248 0.059
polysaccharide metabolic process GO:0005976 39 0.059
mitotic cell cycle process GO:1903047 159 0.058
spermatogenesis GO:0007283 284 0.058
cell division GO:0051301 120 0.057
regulation of polysaccharide metabolic process GO:0032881 13 0.057
chromatin organization GO:0006325 206 0.056
positive regulation of rac gtpase activity GO:0032855 14 0.056
regulation of wnt signaling pathway GO:0030111 123 0.055
mitotic spindle organization GO:0007052 10 0.055
lung development GO:0030324 164 0.055
glucose metabolic process GO:0006006 92 0.055
glycogen metabolic process GO:0005977 32 0.054
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.053
regulation of organelle organization GO:0033043 289 0.053
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.052
positive regulation of cell cycle process GO:0090068 61 0.052
covalent chromatin modification GO:0016569 163 0.051
carbohydrate metabolic process GO:0005975 230 0.051
dna packaging GO:0006323 30 0.050
positive regulation of receptor biosynthetic process GO:0010870 1 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.050
small gtpase mediated signal transduction GO:0007264 97 0.050
ribonucleoprotein complex subunit organization GO:0071826 28 0.050
positive regulation of programmed cell death GO:0043068 218 0.050
posttranscriptional gene silencing GO:0016441 10 0.049
leukocyte differentiation GO:0002521 342 0.049
mesodermal cell migration GO:0008078 4 0.048
multicellular organism growth GO:0035264 161 0.048
carbohydrate catabolic process GO:0016052 32 0.047
intracellular mrna localization GO:0008298 4 0.046
positive regulation of rho gtpase activity GO:0032321 41 0.045
positive regulation of cell death GO:0010942 224 0.045
lipid transport GO:0006869 98 0.045
negative regulation of intracellular signal transduction GO:1902532 167 0.043
neural precursor cell proliferation GO:0061351 121 0.043
cell cycle checkpoint GO:0000075 47 0.043
rna interference GO:0016246 2 0.043
dephosphorylation GO:0016311 129 0.040
receptor mediated endocytosis GO:0006898 51 0.040
regulation of transcription by chromatin organization GO:0034401 0 0.040
organic hydroxy compound metabolic process GO:1901615 203 0.040
cellular lipid metabolic process GO:0044255 323 0.040
maternal determination of anterior posterior axis embryo GO:0008358 2 0.039
negative regulation of wnt signaling pathway GO:0030178 73 0.038
oocyte construction GO:0007308 2 0.038
rhythmic process GO:0048511 174 0.038
regulation of cellular carbohydrate catabolic process GO:0043471 12 0.038
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.038
response to light stimulus GO:0009416 135 0.038
regulation of transferase activity GO:0051338 263 0.037
homeostasis of number of cells GO:0048872 210 0.037
gastrulation GO:0007369 116 0.037
regulation of endocytosis GO:0030100 69 0.037
cellular response to dna damage stimulus GO:0006974 207 0.036
hexose metabolic process GO:0019318 98 0.035
establishment of spindle localization GO:0051293 19 0.035
mitotic nuclear division GO:0007067 48 0.035
regulation of neural precursor cell proliferation GO:2000177 70 0.034
spermatid differentiation GO:0048515 115 0.033
regulation of ras gtpase activity GO:0032318 88 0.033
cellular ketone metabolic process GO:0042180 84 0.033
regulation of generation of precursor metabolites and energy GO:0043467 38 0.033
digestive system development GO:0055123 200 0.032
macromolecule methylation GO:0043414 120 0.032
response to radiation GO:0009314 165 0.031
protein modification by small protein conjugation or removal GO:0070647 207 0.031
regulation of leukocyte differentiation GO:1902105 159 0.031
nuclear transport GO:0051169 139 0.031
positive regulation of nucleoside metabolic process GO:0045979 91 0.030
regulation of phagocytosis GO:0050764 33 0.030
regulation of myeloid leukocyte differentiation GO:0002761 58 0.030
cellular response to inorganic substance GO:0071241 37 0.030
negative regulation of apoptotic cell clearance GO:2000426 1 0.030
establishment or maintenance of cell polarity GO:0007163 86 0.029
negative regulation of protein complex disassembly GO:0043242 22 0.029
nitrogen compound transport GO:0071705 271 0.029
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
epithelial cell development GO:0002064 159 0.028
translation GO:0006412 93 0.028
digestive tract development GO:0048565 190 0.028
regulation of purine nucleotide metabolic process GO:1900542 169 0.028
negative regulation of molecular function GO:0044092 258 0.027
cell adhesion GO:0007155 329 0.027
fertilization GO:0009566 127 0.027
stem cell maintenance GO:0019827 130 0.027
phagocytosis GO:0006909 66 0.026
regulation of kinase activity GO:0043549 249 0.026
spindle organization GO:0007051 28 0.026
myeloid cell differentiation GO:0030099 233 0.026
regulation of glycogen metabolic process GO:0070873 13 0.026
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
mitotic sister chromatid segregation GO:0000070 14 0.026
establishment of organelle localization GO:0051656 122 0.025
ameboidal type cell migration GO:0001667 128 0.025
cellular protein complex assembly GO:0043623 116 0.025
organophosphate catabolic process GO:0046434 232 0.024
gene silencing by rna GO:0031047 19 0.024
appendage morphogenesis GO:0035107 149 0.024
heterochromatin organization GO:0070828 4 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
circadian regulation of gene expression GO:0032922 48 0.024
gtp catabolic process GO:0006184 143 0.024
oocyte axis specification GO:0007309 2 0.024
regulation of protein kinase activity GO:0045859 232 0.024
germ cell development GO:0007281 185 0.024
positive regulation of secretion GO:0051047 130 0.024
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.024
cellular amine metabolic process GO:0044106 44 0.023
plasma lipoprotein particle clearance GO:0034381 13 0.023
regulation of double strand break repair via nonhomologous end joining GO:2001032 2 0.023
respiratory tube development GO:0030323 167 0.023
synapsis GO:0007129 34 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.023
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.023
actomyosin structure organization GO:0031032 56 0.023
regulation of dna dependent dna replication GO:0090329 8 0.023
negative regulation of cardiac muscle cell proliferation GO:0060044 5 0.023
negative regulation of gene silencing GO:0060969 2 0.022
nucleotide metabolic process GO:0009117 332 0.022
negative regulation of chromatin silencing GO:0031936 1 0.022
alcohol metabolic process GO:0006066 116 0.022
3 utr mediated mrna stabilization GO:0070935 2 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
regulation of cell activation GO:0050865 289 0.022
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.022
microtubule polymerization or depolymerization GO:0031109 26 0.022
ventricular system development GO:0021591 27 0.022
forebrain development GO:0030900 302 0.021
engulfment of apoptotic cell GO:0043652 3 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
positive regulation of protein kinase activity GO:0045860 144 0.021
fat cell differentiation GO:0045444 160 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
sensory organ morphogenesis GO:0090596 242 0.021
intracellular protein transport GO:0006886 204 0.021
positive regulation of protein transport GO:0051222 93 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
regulation of mitotic cell cycle GO:0007346 126 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.021
regulation of chromatin silencing GO:0031935 2 0.021
visual perception GO:0007601 52 0.020
adult behavior GO:0030534 135 0.020
histone modification GO:0016570 159 0.020
regulation of cell shape GO:0008360 39 0.020
nucleobase containing compound transport GO:0015931 27 0.020
regulation of androgen receptor signaling pathway GO:0060765 3 0.020
cellular protein complex disassembly GO:0043624 36 0.019
regulation of gtp catabolic process GO:0033124 113 0.019
negative regulation of ras protein signal transduction GO:0046580 18 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
myeloid leukocyte differentiation GO:0002573 119 0.019
regulation of actin cytoskeleton organization GO:0032956 84 0.019
cellular amino acid metabolic process GO:0006520 103 0.018
dna repair GO:0006281 107 0.018
membrane organization GO:0061024 245 0.018
macromolecular complex disassembly GO:0032984 43 0.018
blood circulation GO:0008015 195 0.018
dna hypermethylation GO:0044026 3 0.018
mesoderm development GO:0007498 100 0.018
protein alkylation GO:0008213 81 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
internal peptidyl lysine acetylation GO:0018393 42 0.018
regulation of myeloid cell differentiation GO:0045637 96 0.018
regulation of carbohydrate metabolic process GO:0006109 75 0.018
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.018
nucleotide catabolic process GO:0009166 217 0.018
regulation of protein transport GO:0051223 163 0.018
regulation of hydrolase activity GO:0051336 246 0.018
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.018
positive regulation of endocytosis GO:0045807 42 0.018
protein maturation GO:0051604 176 0.018
spindle localization GO:0051653 22 0.018
regulation of cytoskeleton organization GO:0051493 122 0.017
developmental maturation GO:0021700 193 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
establishment of tissue polarity GO:0007164 28 0.017
circulatory system process GO:0003013 197 0.017
regulation of cell division GO:0051302 76 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.017
nucleoside catabolic process GO:0009164 206 0.017
dna templated transcription termination GO:0006353 4 0.017
myosin filament organization GO:0031033 3 0.017
cell recognition GO:0008037 83 0.017
canonical wnt signaling pathway GO:0060070 130 0.016
cell type specific apoptotic process GO:0097285 268 0.016
axon guidance GO:0007411 141 0.016
negative regulation of b cell differentiation GO:0045578 4 0.016
response to oxidative stress GO:0006979 123 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
sensory perception of light stimulus GO:0050953 54 0.016
multi multicellular organism process GO:0044706 109 0.016
positive regulation of gtp catabolic process GO:0033126 85 0.016
actin cytoskeleton organization GO:0030036 220 0.016
gtp metabolic process GO:0046039 144 0.016
leukocyte migration GO:0050900 124 0.016
spermatid development GO:0007286 108 0.016
peptidyl amino acid modification GO:0018193 336 0.016
regulation of cellular ketone metabolic process GO:0010565 66 0.016
regulation of cellular response to stress GO:0080135 159 0.016
cell cell junction organization GO:0045216 72 0.015
macromolecule deacylation GO:0098732 37 0.015
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 4 0.015
gonad development GO:0008406 141 0.015
Worm
positive regulation of myeloid cell differentiation GO:0045639 43 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
camera type eye development GO:0043010 266 0.015
macromolecule catabolic process GO:0009057 281 0.015
nucleus localization GO:0051647 20 0.015
regulation of b cell activation GO:0050864 81 0.015
positive regulation of transferase activity GO:0051347 167 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
regulation of rho protein signal transduction GO:0035023 71 0.015
fatty acid biosynthetic process GO:0006633 41 0.015
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
positive regulation of growth GO:0045927 104 0.015
activation of rac gtpase activity GO:0032863 2 0.015
sperm individualization GO:0007291 1 0.014
nucleus organization GO:0006997 45 0.014
meiosis ii GO:0007135 7 0.014
response to growth factor GO:0070848 198 0.014
dna alkylation GO:0006305 43 0.014
posttranscriptional gene silencing by rna GO:0035194 10 0.014
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.014
positive regulation of intracellular transport GO:0032388 70 0.014
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
regionalization GO:0003002 337 0.014
oogenesis GO:0048477 56 0.014
genetic imprinting GO:0071514 27 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
response to fibroblast growth factor GO:0071774 47 0.013
cellular chemical homeostasis GO:0055082 215 0.013
multi organism reproductive behavior GO:0044705 29 0.013
negative regulation of mapk cascade GO:0043409 65 0.013
cellular response to oxidative stress GO:0034599 76 0.013
protein heterooligomerization GO:0051291 14 0.013
histone lysine methylation GO:0034968 50 0.013
protein localization to organelle GO:0033365 185 0.013
Human
protein polymerization GO:0051258 57 0.013
microtubule based transport GO:0010970 50 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
heterocycle catabolic process GO:0046700 280 0.013
negative regulation of cytoskeleton organization GO:0051494 36 0.013
development of primary male sexual characteristics GO:0046546 88 0.013
oocyte anterior posterior axis specification GO:0007314 2 0.013
cellularization GO:0007349 1 0.013
regulation of binding GO:0051098 111 0.013
negative regulation of cell cycle phase transition GO:1901988 48 0.013
development of primary sexual characteristics GO:0045137 143 0.013
Worm
megakaryocyte differentiation GO:0030219 26 0.012
multi organism behavior GO:0051705 62 0.012
formation of primary germ layer GO:0001704 77 0.012
regulation of jnk cascade GO:0046328 62 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
signal transduction by p53 class mediator GO:0072331 51 0.012
mitotic sister chromatid cohesion GO:0007064 1 0.012
early endosome to late endosome transport GO:0045022 2 0.012
synaptonemal complex organization GO:0070193 15 0.012
regulation of membrane potential GO:0042391 192 0.012
regulation of gene silencing by rna GO:0060966 5 0.012
microtubule depolymerization GO:0007019 15 0.012
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.012
regulation of cellular amine metabolic process GO:0033238 20 0.012
lymphocyte differentiation GO:0030098 242 0.012
telencephalon development GO:0021537 186 0.012
stem cell differentiation GO:0048863 268 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
heme metabolic process GO:0042168 16 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
neuron apoptotic process GO:0051402 142 0.011
attachment of spindle microtubules to kinetochore GO:0008608 4 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
regulation of nuclear division GO:0051783 56 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
organic cyclic compound catabolic process GO:1901361 295 0.011
protein depolymerization GO:0051261 34 0.011
regulation of cell size GO:0008361 72 0.011
sister chromatid cohesion GO:0007062 12 0.011
activation of cysteine type endopeptidase activity GO:0097202 27 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
positive regulation of protein modification process GO:0031401 299 0.011
regulation of canonical wnt signaling pathway GO:0060828 82 0.011
activation of ras gtpase activity GO:0032856 11 0.011
ribose phosphate metabolic process GO:0019693 291 0.011
meiosis i GO:0007127 60 0.011
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.011
male gonad development GO:0008584 88 0.011
tissue migration GO:0090130 68 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
maintenance of location in cell GO:0051651 24 0.011
establishment of planar polarity GO:0001736 28 0.011
rna processing GO:0006396 105 0.011
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.011
limb morphogenesis GO:0035108 149 0.011
transmission of nerve impulse GO:0019226 76 0.010
mrna metabolic process GO:0016071 84 0.010
b cell activation GO:0042113 161 0.010
learning or memory GO:0007611 148 0.010
regulation of stress activated mapk cascade GO:0032872 69 0.010

Rad21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.139
disease of anatomical entity DOID:7 0 0.139
nervous system disease DOID:863 0 0.139
eye and adnexa disease DOID:1492 0 0.072
eye disease DOID:5614 0 0.072
cornelia de lange syndrome DOID:11725 0 0.016
Human
central nervous system disease DOID:331 0 0.010