|
|
t cell differentiation
|
GO:0030217 |
174 |
0.978
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.972
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.955
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.954
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.953
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.949
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.945
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.936
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.930
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.930
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.924
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.924
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.920
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.920
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.918
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.910
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.907
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.880
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.875
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.875
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.874
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.871
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.861
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.857
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.857
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.847
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.830
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.816
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.812
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.811
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.803
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.790
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.786
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.784
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.780
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.776
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.758
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.756
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.746
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.745
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.744
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.737
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.730
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.714
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.700
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.699
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.697
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.684
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.681
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.674
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.673
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.663
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.647
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.642
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.629
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.617
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.617
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.613
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.606
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.605
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.604
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.603
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.602
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.599
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.592
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.586
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.572
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.572
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.566
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.562
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.547
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.540
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.536
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.532
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.530
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.525
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.524
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.514
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.504
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.504
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.498
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.492
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.488
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.487
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.482
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.481
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.478
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.469
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.466
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.461
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.461
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.458
|
|
|
|
granzyme mediated apoptotic signaling pathway
|
GO:0008626 |
1 |
0.452
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.451
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.439
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.431
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.431
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.425
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.424
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.418
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.413
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.411
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.399
|
Human Mouse |
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.397
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.393
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.389
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.388
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.387
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.386
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.382
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.379
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.379
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.375
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.375
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.370
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.369
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.368
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.368
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.364
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.362
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.360
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.359
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.359
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.359
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.358
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.355
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.350
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.349
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.345
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.344
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.340
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.338
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.335
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.335
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.334
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.331
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.331
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.328
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.326
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.321
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.317
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.314
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.314
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.311
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.308
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.304
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.302
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.302
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.301
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.301
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.299
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.294
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.293
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.293
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.293
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.292
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.291
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.291
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.290
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.290
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.290
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.289
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.287
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.283
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.280
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.278
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.278
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.277
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.277
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.276
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.273
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.267
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.267
|
|
|
|
tolerance induction
|
GO:0002507 |
14 |
0.266
|
|
|
|
neutrophil mediated killing of gram positive bacterium
|
GO:0070946 |
2 |
0.265
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.265
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.263
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.261
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.259
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.258
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.256
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.250
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.249
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.247
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.246
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.244
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.243
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.243
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.242
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.241
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.239
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.238
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.233
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.230
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.229
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.229
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.228
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.228
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.227
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.226
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.225
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.225
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.224
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.223
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.222
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
19 |
0.222
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.220
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.219
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.217
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.216
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.215
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.214
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.213
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.207
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.207
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.204
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.203
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.203
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.201
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.201
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.200
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.197
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.196
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.195
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.192
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.191
|
|
|
|
regulation of angiotensin levels in blood
|
GO:0002002 |
4 |
0.189
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.187
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.186
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.184
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.184
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.184
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.182
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.180
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.179
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.179
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.177
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.175
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.173
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.173
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.173
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.171
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.171
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.170
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.169
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.168
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.167
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.165
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.164
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.164
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.164
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.164
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.163
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.161
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.161
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.161
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.161
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.160
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.159
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.158
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.156
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.155
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.155
|
|
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.155
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.154
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.154
|
|
|
|
regulation of t helper 1 cell cytokine production
|
GO:2000554 |
1 |
0.153
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.153
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.152
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.151
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.150
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.150
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.148
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.146
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.146
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.146
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.145
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.145
|
|
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.143
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.143
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.141
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.141
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.139
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.139
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.138
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.137
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.136
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.136
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.136
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.135
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.135
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.134
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.134
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.132
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.132
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.132
|
|
|
|
t cell mediated cytotoxicity
|
GO:0001913 |
26 |
0.131
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.130
|
|
|
|
positive regulation of syncytium formation by plasma membrane fusion
|
GO:0060143 |
17 |
0.129
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.128
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.128
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.128
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.128
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.127
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.127
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.125
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.124
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.124
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.124
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.123
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.123
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.123
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.122
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.122
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.121
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.121
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.120
|
|
|
|
microglia development
|
GO:0014005 |
2 |
0.119
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.119
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.118
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.117
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.117
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.117
|
|
|
|
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway
|
GO:0010579 |
3 |
0.117
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.116
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.116
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.115
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.114
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.114
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.114
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.113
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.113
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.113
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.113
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.113
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.112
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.112
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.112
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
7 |
0.112
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.111
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.111
|
|
|
|
killing by host of symbiont cells
|
GO:0051873 |
11 |
0.110
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.110
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.110
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.110
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.109
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.109
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.109
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.108
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.108
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.108
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.108
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.107
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.107
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.107
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.107
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.106
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.105
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.105
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.105
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.105
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.105
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.104
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.104
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.104
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.104
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.103
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.103
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.103
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.103
|
|
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
13 |
0.102
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.101
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.101
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.100
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.100
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.100
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.100
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.099
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.098
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.098
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.098
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.098
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.096
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.096
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.096
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.095
|
|
|
|
positive regulation of dendritic cell apoptotic process
|
GO:2000670 |
3 |
0.095
|
|
|
|
negative regulation of myeloid cell apoptotic process
|
GO:0033033 |
11 |
0.095
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.095
|
|
|
|
neutrophil mediated immunity
|
GO:0002446 |
19 |
0.095
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.095
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.094
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.094
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.093
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.092
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.091
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.091
|
|
|
|
monocarboxylic acid transport
|
GO:0015718 |
44 |
0.091
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.091
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.091
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.091
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.090
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.090
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.090
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.089
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.089
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.088
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.088
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.088
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.087
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.087
|
|
|
|
disruption by host of symbiont cells
|
GO:0051852 |
11 |
0.087
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.086
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.086
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.086
|
|
|
|
regulation of podosome assembly
|
GO:0071801 |
3 |
0.085
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.085
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.083
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.083
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.082
|
|
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.081
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.080
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.080
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.079
|
|
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.079
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.079
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.079
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.078
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.078
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.078
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.078
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.078
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.078
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.078
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.078
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.077
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.077
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.077
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.077
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.077
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.076
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.076
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.076
|
Human Mouse |
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.075
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.075
|
|
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
19 |
0.074
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.073
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.073
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.073
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.072
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.072
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.072
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.071
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.071
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.071
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.071
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.071
|
|
|
|
regulation of acute inflammatory response to non antigenic stimulus
|
GO:0002877 |
2 |
0.071
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.071
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.070
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.070
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
18 |
0.070
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.069
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.069
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.069
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.069
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.069
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.069
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.069
|
|
|
|
dendritic cell apoptotic process
|
GO:0097048 |
3 |
0.069
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.069
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.068
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.068
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.068
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.068
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.068
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.068
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.068
|
|
|
|
cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0002361 |
4 |
0.067
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.067
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.067
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.067
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.066
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.066
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.066
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.066
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.066
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.065
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.065
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.064
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.064
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.064
|
|
|
|
nk t cell differentiation
|
GO:0001865 |
8 |
0.064
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.064
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.063
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.063
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.063
|
|
