Mus musculus

87 known processes

Prdx4

peroxiredoxin 4

(Aliases: AOE372,Prx4,TRANK,Prx-iv)

Prdx4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.088
peptidyl amino acid modification GO:0018193 336 0.074
carbohydrate metabolic process GO:0005975 230 0.063
cellular ketone metabolic process GO:0042180 84 0.057
heterocycle catabolic process GO:0046700 280 0.050
negative regulation of molecular function GO:0044092 258 0.047
Mouse
monocarboxylic acid metabolic process GO:0032787 191 0.046
cellular response to dna damage stimulus GO:0006974 207 0.045
regulation of cellular ketone metabolic process GO:0010565 66 0.045
amine metabolic process GO:0009308 45 0.042
male gamete generation GO:0048232 285 0.039
cellular amino acid metabolic process GO:0006520 103 0.038
aromatic compound catabolic process GO:0019439 286 0.038
negative regulation of protein metabolic process GO:0051248 282 0.034
carbohydrate derivative biosynthetic process GO:1901137 183 0.034
cellular lipid metabolic process GO:0044255 323 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
cellular amine metabolic process GO:0044106 44 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
skeletal system development GO:0001501 356 0.027
endomembrane system organization GO:0010256 147 0.027
cellular macromolecule catabolic process GO:0044265 206 0.026
positive regulation of coagulation GO:0050820 13 0.025
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.025
cellular response to lipid GO:0071396 145 0.025
Mouse
membrane organization GO:0061024 245 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
glycoprotein biosynthetic process GO:0009101 89 0.023
regulation of cellular catabolic process GO:0031329 242 0.023
organic hydroxy compound metabolic process GO:1901615 203 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
mitotic cell cycle GO:0000278 195 0.022
spermatogenesis GO:0007283 284 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
regulation of cell cycle GO:0051726 281 0.022
circulatory system process GO:0003013 197 0.022
meiotic nuclear division GO:0007126 115 0.022
small gtpase mediated signal transduction GO:0007264 97 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
lipid biosynthetic process GO:0008610 179 0.021
glycoprotein metabolic process GO:0009100 116 0.020
intracellular protein transport GO:0006886 204 0.020
Mouse
mitotic cytokinesis GO:0000281 4 0.020
response to organic cyclic compound GO:0014070 198 0.020
regulation of protein localization GO:0032880 231 0.020
Mouse
positive regulation of apoptotic process GO:0043065 217 0.020
regulation of response to wounding GO:1903034 189 0.019
Mouse
regulation of establishment of protein localization GO:0070201 181 0.019
Mouse
regulation of hydrolase activity GO:0051336 246 0.019
asymmetric stem cell division GO:0098722 3 0.018
blood circulation GO:0008015 195 0.018
hexose metabolic process GO:0019318 98 0.018
monosaccharide metabolic process GO:0005996 106 0.018
organelle assembly GO:0070925 177 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
lymphocyte proliferation GO:0046651 164 0.018
Mouse
positive regulation of programmed cell death GO:0043068 218 0.018
dna metabolic process GO:0006259 303 0.017
meiotic cell cycle process GO:1903046 77 0.017
response to inorganic substance GO:0010035 96 0.017
Mouse Worm
meiosis i GO:0007127 60 0.017
response to acid chemical GO:0001101 111 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
Mouse
chemotaxis GO:0006935 247 0.017
regulation of cell activation GO:0050865 289 0.017
Mouse
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
inflammatory response GO:0006954 244 0.017
Mouse
innate immune response GO:0045087 157 0.017
Mouse
organelle localization GO:0051640 179 0.017
wound healing GO:0042060 157 0.016
Mouse
ribose phosphate metabolic process GO:0019693 291 0.016
leukocyte differentiation GO:0002521 342 0.016
Mouse
positive regulation of protein modification process GO:0031401 299 0.016
Mouse
regulation of membrane potential GO:0042391 192 0.016
nucleotide metabolic process GO:0009117 332 0.016
regulation of system process GO:0044057 200 0.016
regulation of hormone levels GO:0010817 211 0.016
positive regulation of cell death GO:0010942 224 0.016
sensory perception GO:0007600 245 0.016
cellular chemical homeostasis GO:0055082 215 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
purine containing compound metabolic process GO:0072521 311 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
Mouse
glycosylation GO:0070085 62 0.016
peptidyl glutamic acid modification GO:0018200 13 0.016
regulation of protein kinase activity GO:0045859 232 0.016
Mouse
meiotic cell cycle GO:0051321 122 0.015
regulation of cellular response to stress GO:0080135 159 0.015
Mouse
wnt signaling pathway GO:0016055 188 0.015
muscle cell differentiation GO:0042692 261 0.015
placenta development GO:0001890 140 0.015
Mouse
nuclear division GO:0000280 158 0.015
organonitrogen compound catabolic process GO:1901565 264 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
regulation of inflammatory response GO:0050727 147 0.015
skin development GO:0043588 220 0.015
epithelial cell proliferation GO:0050673 174 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
macromolecule catabolic process GO:0009057 281 0.015
response to nutrient levels GO:0031667 109 0.015
fatty acid metabolic process GO:0006631 121 0.015
purine nucleotide metabolic process GO:0006163 302 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
Mouse
glucose homeostasis GO:0042593 128 0.014
immune effector process GO:0002252 321 0.014
Mouse
cognition GO:0050890 149 0.014
negative regulation of cell activation GO:0050866 111 0.014
Mouse
anion transport GO:0006820 177 0.014
response to organonitrogen compound GO:0010243 246 0.014
regulation of organelle organization GO:0033043 289 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
germ cell development GO:0007281 185 0.014
regulation of secretion by cell GO:1903530 249 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
negative regulation of phosphorylation GO:0042326 166 0.013
establishment of organelle localization GO:0051656 122 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
Mouse
modification dependent protein catabolic process GO:0019941 133 0.013
response to oxidative stress GO:0006979 123 0.013
Yeast Mouse Worm
forebrain development GO:0030900 302 0.013
nitrogen compound transport GO:0071705 271 0.013
Mouse
myeloid cell differentiation GO:0030099 233 0.013
Mouse
regulation of transferase activity GO:0051338 263 0.013
Mouse
regulation of protein maturation GO:1903317 96 0.013
regulation of exit from mitosis GO:0007096 1 0.013
cellular response to antibiotic GO:0071236 4 0.013
macromolecule glycosylation GO:0043413 55 0.013
cell type specific apoptotic process GO:0097285 268 0.013
striated muscle cell development GO:0055002 125 0.013
mapk cascade GO:0000165 281 0.013
Mouse
ribonucleotide catabolic process GO:0009261 208 0.013
myeloid cell homeostasis GO:0002262 114 0.013
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.013
organelle fission GO:0048285 170 0.013
bone development GO:0060348 120 0.013
cellular homeostasis GO:0019725 240 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
cell division GO:0051301 120 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
Mouse
multicellular organismal signaling GO:0035637 91 0.013
gland development GO:0048732 330 0.012
Mouse
response to molecule of bacterial origin GO:0002237 143 0.012
Mouse
apoptotic signaling pathway GO:0097190 306 0.012
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.012
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
ras protein signal transduction GO:0007265 77 0.012
lateral inhibition GO:0046331 1 0.012
respiratory tube development GO:0030323 167 0.012
alcohol metabolic process GO:0006066 116 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
mrna metabolic process GO:0016071 84 0.012
small molecule biosynthetic process GO:0044283 132 0.012
nucleotide catabolic process GO:0009166 217 0.012
muscle tissue development GO:0060537 308 0.012
regulation of anatomical structure size GO:0090066 178 0.012
epidermis development GO:0008544 187 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
positive regulation of cell development GO:0010720 237 0.012
cellular response to oxidative stress GO:0034599 76 0.012
Yeast Mouse Worm
retrograde transport endosome to golgi GO:0042147 2 0.012
nucleoside catabolic process GO:0009164 206 0.012
transmembrane transport GO:0055085 412 0.012
cilium assembly GO:0042384 81 0.012
protein processing GO:0016485 163 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
neuron death GO:0070997 154 0.012
respiratory system development GO:0060541 190 0.012
epithelial cell development GO:0002064 159 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
chromatin organization GO:0006325 206 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
organic anion transport GO:0015711 137 0.012
cation transmembrane transport GO:0098655 266 0.012
cytoplasmic transport GO:0016482 234 0.012
Mouse
regulation of defense response GO:0031347 233 0.011
heart contraction GO:0060047 93 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
covalent chromatin modification GO:0016569 163 0.011
cytokine production GO:0001816 319 0.011
peptide transport GO:0015833 133 0.011
Mouse
positive regulation of protein transport GO:0051222 93 0.011
regulation of secretion GO:0051046 274 0.011
axonogenesis GO:0007409 274 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
activation of immune response GO:0002253 138 0.011
urogenital system development GO:0001655 261 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
muscle system process GO:0003012 141 0.011
leukocyte proliferation GO:0070661 172 0.011
Mouse
regulation of blood circulation GO:1903522 93 0.011
regulation of protein transport GO:0051223 163 0.011
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.011
regulation of body fluid levels GO:0050878 162 0.011
Mouse
protein glycosylation GO:0006486 55 0.011
regulation of t cell activation GO:0050863 170 0.011
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
transmission of nerve impulse GO:0019226 76 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
regulation of mapk cascade GO:0043408 248 0.011
Mouse
response to extracellular stimulus GO:0009991 127 0.011
spindle assembly involved in meiosis GO:0090306 4 0.011
heart process GO:0003015 94 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
neural precursor cell proliferation GO:0061351 121 0.011
neural tube development GO:0021915 160 0.011
positive regulation of nervous system development GO:0051962 221 0.011
compound eye development GO:0048749 1 0.011
spindle assembly involved in mitosis GO:0090307 4 0.011
t cell activation GO:0042110 289 0.011
Mouse
response to reactive oxygen species GO:0000302 56 0.010
Mouse Worm
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
negative regulation of protein modification process GO:0031400 163 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
action potential GO:0001508 78 0.010
dna repair GO:0006281 107 0.010
sequestering of calcium ion GO:0051208 18 0.010
fertilization GO:0009566 127 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
carbohydrate homeostasis GO:0033500 128 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.010
homeostasis of number of cells GO:0048872 210 0.010
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.010
glucose metabolic process GO:0006006 92 0.010
leukocyte mediated immunity GO:0002443 174 0.010
Mouse
rho protein signal transduction GO:0007266 32 0.010
organophosphate catabolic process GO:0046434 232 0.010
regulation of ossification GO:0030278 112 0.010
maintenance of location GO:0051235 89 0.010

Prdx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.035
disease of anatomical entity DOID:7 0 0.029
musculoskeletal system disease DOID:17 0 0.029
connective tissue disease DOID:65 0 0.029
bone development disease DOID:0080006 0 0.022
bone disease DOID:0080001 0 0.022
inherited metabolic disorder DOID:655 0 0.011
carbohydrate metabolic disorder DOID:2978 0 0.011
nervous system disease DOID:863 0 0.010