Mus musculus

0 known processes

Zzz3

zinc finger, ZZ domain containing 3

(Aliases: AI481057,3110065C23Rik,R75514,6430567E01Rik,AW556059,AA408566)

Zzz3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.236
ribosomal small subunit biogenesis GO:0042274 4 0.149
leukocyte differentiation GO:0002521 342 0.129
regulation of cell cycle GO:0051726 281 0.118
hematopoietic progenitor cell differentiation GO:0002244 143 0.107
mitotic cell cycle GO:0000278 195 0.102
posttranscriptional regulation of gene expression GO:0010608 155 0.097
ossification GO:0001503 216 0.090
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.084
regulation of neuron differentiation GO:0045664 281 0.073
regulation of protein stability GO:0031647 52 0.071
skeletal system development GO:0001501 356 0.064
myeloid cell differentiation GO:0030099 233 0.061
regulation of nucleoside metabolic process GO:0009118 130 0.061
covalent chromatin modification GO:0016569 163 0.060
rna processing GO:0006396 105 0.059
t cell activation GO:0042110 289 0.057
mitotic cell cycle process GO:1903047 159 0.051
oocyte axis specification GO:0007309 2 0.049
fat cell differentiation GO:0045444 160 0.048
microtubule cytoskeleton organization GO:0000226 157 0.048
chromatin organization GO:0006325 206 0.047
protein localization to organelle GO:0033365 185 0.046
cellular ketone metabolic process GO:0042180 84 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
negative regulation of cellular amine metabolic process GO:0033239 1 0.043
amine metabolic process GO:0009308 45 0.042
cell maturation GO:0048469 127 0.042
regulation of cell cycle process GO:0010564 160 0.041
maturation of ssu rrna GO:0030490 1 0.039
axonogenesis GO:0007409 274 0.039
regulation of purine nucleotide metabolic process GO:1900542 169 0.038
regulation of organelle organization GO:0033043 289 0.038
stem cell development GO:0048864 219 0.038
microtubule based process GO:0007017 236 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.036
negative regulation of response to wounding GO:1903035 77 0.034
positive regulation of nucleotide metabolic process GO:0045981 114 0.034
myeloid leukocyte differentiation GO:0002573 119 0.033
protein ubiquitination GO:0016567 171 0.033
regulation of nucleotide metabolic process GO:0006140 169 0.033
meiotic nuclear division GO:0007126 115 0.033
positive regulation of programmed cell death GO:0043068 218 0.032
stem cell differentiation GO:0048863 268 0.032
negative regulation of protein modification process GO:0031400 163 0.032
regulation of microtubule based process GO:0032886 52 0.032
male gamete generation GO:0048232 285 0.032
gonad development GO:0008406 141 0.031
compound eye development GO:0048749 1 0.031
regulation of leukocyte differentiation GO:1902105 159 0.030
protein modification by small protein conjugation or removal GO:0070647 207 0.030
oocyte construction GO:0007308 2 0.030
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
cell fate commitment GO:0045165 210 0.029
ras protein signal transduction GO:0007265 77 0.029
positive regulation of leukocyte differentiation GO:1902107 86 0.029
skeletal system morphogenesis GO:0048705 203 0.028
nuclear division GO:0000280 158 0.027
mitotic nuclear division GO:0007067 48 0.026
regulation of cellular component size GO:0032535 121 0.026
osteoclast differentiation GO:0030316 62 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
regulation of protein localization GO:0032880 231 0.025
developmental maturation GO:0021700 193 0.025
regulation of mapk cascade GO:0043408 248 0.025
blood vessel morphogenesis GO:0048514 285 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.025
peptidyl amino acid modification GO:0018193 336 0.024
camera type eye development GO:0043010 266 0.024
negative regulation of inflammatory response GO:0050728 61 0.024
somatic stem cell maintenance GO:0035019 47 0.024
regulation of response to wounding GO:1903034 189 0.023
positive regulation of nucleoside metabolic process GO:0045979 91 0.023
cell adhesion GO:0007155 329 0.023
t cell differentiation GO:0030217 174 0.022
rna splicing GO:0008380 54 0.022
negative regulation of cell development GO:0010721 169 0.021
development of primary sexual characteristics GO:0045137 143 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.021
positive regulation of cell death GO:0010942 224 0.021
regulation of neuron projection development GO:0010975 169 0.021
developmental growth involved in morphogenesis GO:0060560 138 0.020
response to growth factor GO:0070848 198 0.020
regulation of inflammatory response GO:0050727 147 0.020
germ cell development GO:0007281 185 0.020
rho protein signal transduction GO:0007266 32 0.020
negative regulation of neuron apoptotic process GO:0043524 92 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
cellular response to peptide hormone stimulus GO:0071375 92 0.019
positive regulation of neuron differentiation GO:0045666 141 0.019
mapk cascade GO:0000165 281 0.019
regulation of neuron apoptotic process GO:0043523 122 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
organelle fission GO:0048285 170 0.019
regulation of cell activation GO:0050865 289 0.019
protein stabilization GO:0050821 25 0.019
cellular amine metabolic process GO:0044106 44 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
body morphogenesis GO:0010171 45 0.018
regulation of ossification GO:0030278 112 0.017
respiratory tube development GO:0030323 167 0.017
cellular amino acid metabolic process GO:0006520 103 0.017
apoptotic signaling pathway GO:0097190 306 0.017
negative regulation of neuron death GO:1901215 98 0.017
multicellular organism growth GO:0035264 161 0.017
response to insulin GO:0032868 100 0.017
digestive tract development GO:0048565 190 0.017
negative regulation of nervous system development GO:0051961 156 0.017
positive regulation of cell development GO:0010720 237 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
adult behavior GO:0030534 135 0.017
myeloid cell homeostasis GO:0002262 114 0.017
secretory granule organization GO:0033363 20 0.016
regulation of meiotic cell cycle GO:0051445 34 0.016
cell type specific apoptotic process GO:0097285 268 0.016
neuron apoptotic process GO:0051402 142 0.016
nuclear import GO:0051170 95 0.016
protein localization to nucleus GO:0034504 121 0.016
lymphocyte differentiation GO:0030098 242 0.016
regulation of protein transport GO:0051223 163 0.016
chemotaxis GO:0006935 247 0.016
positive regulation of nervous system development GO:0051962 221 0.016
regulation of neuron death GO:1901214 134 0.015
inflammatory response GO:0006954 244 0.015
positive regulation of rac protein signal transduction GO:0035022 1 0.015
gastrulation GO:0007369 116 0.015
nucleoside metabolic process GO:0009116 246 0.015
regulation of myeloid leukocyte differentiation GO:0002761 58 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
regulation of cell cycle phase transition GO:1901987 77 0.015
visual perception GO:0007601 52 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
cellular response to insulin stimulus GO:0032869 78 0.015
mrna splicing via spliceosome GO:0000398 43 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
single organism nuclear import GO:1902593 95 0.014
skin development GO:0043588 220 0.014
erbb signaling pathway GO:0038127 32 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.014
regulation of cytokine production GO:0001817 266 0.014
intracellular protein transport GO:0006886 204 0.014
female gamete generation GO:0007292 74 0.014
regulation of kinase activity GO:0043549 249 0.014
regulation of anatomical structure size GO:0090066 178 0.014
placenta development GO:0001890 140 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
cellular response to external stimulus GO:0071496 88 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
cell division GO:0051301 120 0.014
endonucleolytic cleavage of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000479 1 0.013
regulation of myeloid cell differentiation GO:0045637 96 0.013
regulation of cell projection organization GO:0031344 206 0.013
endocytosis GO:0006897 168 0.013
negative regulation of dna replication GO:0008156 4 0.013
cognition GO:0050890 149 0.013
positive regulation of immature t cell proliferation in thymus GO:0033092 3 0.013
angiogenesis GO:0001525 201 0.013
protein complex disassembly GO:0043241 40 0.013
gene silencing by rna GO:0031047 19 0.013
mitotic chromosome condensation GO:0007076 1 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
embryonic skeletal system development GO:0048706 120 0.013
digestive system development GO:0055123 200 0.013
spermatogenesis GO:0007283 284 0.012
stem cell maintenance GO:0019827 130 0.012
aromatic compound catabolic process GO:0019439 286 0.012
b cell activation GO:0042113 161 0.012
regulation of insulin receptor signaling pathway GO:0046626 21 0.012
epithelial cell proliferation GO:0050673 174 0.012
t cell differentiation in thymus GO:0033077 77 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
gliogenesis GO:0042063 141 0.012
regulation of hormone levels GO:0010817 211 0.012
purine containing compound metabolic process GO:0072521 311 0.012
striated muscle tissue development GO:0014706 293 0.012
actin cytoskeleton organization GO:0030036 220 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
regulation of osteoblast differentiation GO:0045667 67 0.012
homeostasis of number of cells GO:0048872 210 0.012
endonucleolytic cleavage involved in rrna processing GO:0000478 1 0.012
cellular response to oxidative stress GO:0034599 76 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
cation transmembrane transport GO:0098655 266 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
neuron death GO:0070997 154 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
regulation of hydrolase activity GO:0051336 246 0.011
maturation of 5 8s rrna GO:0000460 1 0.011
regulation of cellular response to growth factor stimulus GO:0090287 82 0.011
regulation of dna replication GO:0006275 17 0.011
chromatin modification GO:0016568 187 0.011
macromolecule catabolic process GO:0009057 281 0.011
nucleoside phosphate metabolic process GO:0006753 338 0.011
regulation of nuclear division GO:0051783 56 0.011
wound healing GO:0042060 157 0.011
appendage morphogenesis GO:0035107 149 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.010
mesenchyme development GO:0060485 152 0.010
protein maturation GO:0051604 176 0.010
cytokine production GO:0001816 319 0.010
neuroepithelial cell differentiation GO:0060563 37 0.010
gland development GO:0048732 330 0.010
regulation of t cell activation GO:0050863 170 0.010
mrna metabolic process GO:0016071 84 0.010
purine nucleoside triphosphate metabolic process GO:0009144 226 0.010
response to peptide hormone GO:0043434 127 0.010
regulation of muscle tissue development GO:1901861 97 0.010

Zzz3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.034
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
sensory system disease DOID:0050155 0 0.012
large intestine cancer DOID:5672 0 0.012
colon cancer DOID:219 0 0.012
gastrointestinal system cancer DOID:3119 0 0.012
intestinal cancer DOID:10155 0 0.012
colorectal cancer DOID:9256 0 0.012
endocrine gland cancer DOID:170 0 0.012
thyroid cancer DOID:1781 0 0.012
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010