|
|
antigen processing and presentation of exogenous antigen
|
GO:0019884 |
26 |
0.999
|
|
|
|
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii
|
GO:0002504 |
17 |
0.996
|
|
|
|
antigen processing and presentation of peptide antigen via mhc class ii
|
GO:0002495 |
17 |
0.988
|
|
|
|
antigen processing and presentation of exogenous peptide antigen via mhc class ii
|
GO:0019886 |
14 |
0.981
|
|
|
|
macrophage migration inhibitory factor signaling pathway
|
GO:0035691 |
2 |
0.977
|
|
|
|
antigen processing and presentation of peptide antigen
|
GO:0048002 |
29 |
0.947
|
|
|
|
antigen processing and presentation of exogenous peptide antigen
|
GO:0002478 |
21 |
0.911
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.853
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.733
|
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
11 |
0.667
|
|
|
|
positive regulation of germinal center formation
|
GO:0002636 |
5 |
0.568
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.529
|
|
|
|
de novo protein folding
|
GO:0006458 |
9 |
0.504
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.478
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.470
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.448
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.441
|
|
|
|
b cell selection
|
GO:0002339 |
3 |
0.435
|
|
|
|
regulation of antigen processing and presentation
|
GO:0002577 |
10 |
0.432
|
|
|
|
protein folding
|
GO:0006457 |
28 |
0.411
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.411
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.368
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.356
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.352
|
|
|
|
chondroitin sulfate metabolic process
|
GO:0030204 |
17 |
0.334
|
|
|
|
proteoglycan metabolic process
|
GO:0006029 |
38 |
0.325
|
|
|
|
germinal center formation
|
GO:0002467 |
16 |
0.320
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.316
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.314
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.314
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.311
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.285
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.276
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.274
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.271
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.268
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.267
|
|
|
|
positive thymic t cell selection
|
GO:0045059 |
13 |
0.266
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.257
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.254
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.247
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.241
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.241
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.240
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.235
|
Mouse |
|
|
prostaglandin metabolic process
|
GO:0006693 |
11 |
0.234
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.231
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.228
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.227
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.227
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.223
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.221
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.220
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.217
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.215
|
|
|
|
negative regulation of b cell apoptotic process
|
GO:0002903 |
7 |
0.209
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.207
|
|
|
|
regulation of germinal center formation
|
GO:0002634 |
10 |
0.206
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.204
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.200
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.199
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.194
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.193
|
|
|
|
positive regulation of macrophage cytokine production
|
GO:0060907 |
7 |
0.192
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.190
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.188
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.188
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.187
|
|
|
|
chaperone mediated protein folding
|
GO:0061077 |
10 |
0.183
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.181
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.176
|
|
|
|
fatty acid derivative biosynthetic process
|
GO:1901570 |
15 |
0.172
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.171
|
|
|
|
unsaturated fatty acid metabolic process
|
GO:0033559 |
31 |
0.170
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.160
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
20 |
0.159
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.150
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.149
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.145
|
|
|
|
chondroitin sulfate proteoglycan metabolic process
|
GO:0050654 |
20 |
0.141
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.140
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.135
|
|
|
|
fatty acid derivative metabolic process
|
GO:1901568 |
33 |
0.134
|
|
|
|
icosanoid metabolic process
|
GO:0006690 |
33 |
0.129
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.127
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.121
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.119
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.117
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.115
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.115
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.115
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.113
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.113
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.112
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.112
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.112
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.111
|
|
|
|
unsaturated fatty acid biosynthetic process
|
GO:0006636 |
15 |
0.110
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.106
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.104
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.100
|
|
|
|
regulation of macrophage cytokine production
|
GO:0010935 |
8 |
0.099
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.098
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.098
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.098
|
|
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
61 |
0.096
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.092
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.091
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.090
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.089
|
|
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
13 |
0.089
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.088
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.088
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.088
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.087
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.087
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.087
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
47 |
0.084
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.083
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.083
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.081
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.080
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.079
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.078
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.077
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.077
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.077
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.077
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.075
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.074
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.074
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.073
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.073
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.073
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.073
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.072
|
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
24 |
0.071
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.071
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.070
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.070
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.068
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.068
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
23 |
0.068
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.067
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.067
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.066
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.066
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.065
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.064
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.064
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.063
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.063
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.062
|
|
|
|
positive regulation of antigen processing and presentation
|
GO:0002579 |
10 |
0.061
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.060
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.059
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.059
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.059
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.058
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.058
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.058
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.058
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.057
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.057
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.056
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.056
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.056
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.055
|
|
|
|
peptide cross linking via chondroitin 4 sulfate glycosaminoglycan
|
GO:0019800 |
8 |
0.054
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.054
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.054
|
|
|
|
myeloid leukocyte cytokine production
|
GO:0061082 |
12 |
0.054
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
34 |
0.053
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.053
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.052
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.052
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.052
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.052
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.051
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.051
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.050
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.050
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.048
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.047
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.047
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.046
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
13 |
0.046
|
|
|
|
negative regulation of interferon beta biosynthetic process
|
GO:0045358 |
1 |
0.045
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
33 |
0.045
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.045
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.045
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.044
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.044
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.044
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.044
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.044
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.043
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.043
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
19 |
0.043
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.043
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.043
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.043
|
|
|
|
positive regulation of type 2 immune response
|
GO:0002830 |
9 |
0.042
|
|
|
|
cellular response to ammonium ion
|
GO:0071242 |
2 |
0.042
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
34 |
0.042
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.042
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.041
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.041
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.041
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.041
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.041
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.041
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.040
|
|
|
|
glycosaminoglycan metabolic process
|
GO:0030203 |
34 |
0.039
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.039
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.038
|
|
|
|
regulation of intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:1902253 |
13 |
0.038
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.037
|
|
|
|
icosanoid biosynthetic process
|
GO:0046456 |
15 |
0.037
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.037
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.037
|
|
|
|
cd8 positive alpha beta t cell proliferation
|
GO:0035740 |
1 |
0.037
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.036
|
|
|
|
macrophage cytokine production
|
GO:0010934 |
9 |
0.036
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.036
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.035
|
|
|
|
regulation of cd8 positive alpha beta t cell proliferation
|
GO:2000564 |
1 |
0.035
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.034
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.034
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.033
|
|
|
|
positive regulation of myeloid leukocyte cytokine production involved in immune response
|
GO:0061081 |
9 |
0.033
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.033
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.033
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.033
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.033
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.033
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.032
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.032
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.032
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.032
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.032
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.031
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.031
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.030
|
Mouse |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.030
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.030
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.030
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.030
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.030
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.029
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.029
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.029
|
|
|
|
regulation of retina development in camera type eye
|
GO:1902866 |
3 |
0.029
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.029
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.029
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.028
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.028
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.028
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.028
|
|
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
1 |
0.028
|
|
|
|
regulation of intrinsic apoptotic signaling pathway in response to dna damage
|
GO:1902229 |
14 |
0.028
|
|
|
|
negative regulation of dna damage response signal transduction by p53 class mediator
|
GO:0043518 |
5 |
0.028
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.028
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.028
|
|
|
|
prostanoid biosynthetic process
|
GO:0046457 |
8 |
0.027
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.027
|
|
|
|
negative regulation of gluconeogenesis
|
GO:0045721 |
9 |
0.027
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.027
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.027
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.027
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.027
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.026
|
|
|
|
negative regulation of mature b cell apoptotic process
|
GO:0002906 |
4 |
0.026
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.026
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.026
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.026
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.026
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.026
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.026
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.026
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.025
|
|
|
|
regulation of myd88 dependent toll like receptor signaling pathway
|
GO:0034124 |
2 |
0.025
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.025
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.025
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.025
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.025
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.025
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.025
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.024
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.024
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.024
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.024
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.024
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.024
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.024
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.024
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.024
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.024
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.023
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.023
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.023
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.023
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.023
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.023
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.023
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.023
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.023
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.023
|
|
|
|
negative regulation of interferon beta production
|
GO:0032688 |
3 |
0.022
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.022
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.022
|
|
|
|
negative regulation of peptide secretion
|
GO:0002792 |
16 |
0.022
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.022
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.022
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.022
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.022
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.022
|
|
|
|
response to ammonium ion
|
GO:0060359 |
21 |
0.022
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.022
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.022
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.022
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.022
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.022
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.021
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.021
|
|
|
|
peptide cross linking
|
GO:0018149 |
10 |
0.021
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.021
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.021
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.021
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.021
|
|
|
|
lamellipodium organization
|
GO:0097581 |
29 |
0.021
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.021
|
|
|
|
myofibril assembly
|
GO:0030239 |
34 |
0.021
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.021
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.021
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.021
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.021
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.021
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.020
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.020
|
|
|
|
response to morphine
|
GO:0043278 |
9 |
0.020
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.020
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.020
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.020
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.020
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.020
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.020
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.020
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.020
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.020
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.020
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.020
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.020
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.020
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.020
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.020
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.020
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.019
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.019
|
|
|
|
smooth muscle cell chemotaxis
|
GO:0071670 |
2 |
0.019
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.019
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.019
|
|
|
|
cell migration involved in metanephros development
|
GO:0035788 |
2 |
0.019
|
|
|
|
regulation of chemokine c x c motif ligand 2 production
|
GO:2000341 |
3 |
0.019
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.019
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.019
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.019
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.019
|
|
|
|
negative regulation of defense response to virus by host
|
GO:0050689 |
1 |
0.019
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.019
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.019
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.018
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.018
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.018
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.018
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.018
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.018
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.018
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.018
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.018
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.018
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.018
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.018
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.018
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.018
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.017
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.017
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.017
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.017
|
|
|
|
regulation of actin nucleation
|
GO:0051125 |
4 |
0.017
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.017
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.017
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.017
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.017
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.017
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.017
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.017
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.017
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.017
|
|
|
|
prostaglandin biosynthetic process
|
GO:0001516 |
8 |
0.017
|
|
|
|
glomerular visceral epithelial cell development
|
GO:0072015 |
6 |
0.016
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.016
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.016
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.016
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.016
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.016
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.016
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.016
|
|
|
|
t helper 17 cell differentiation
|
GO:0072539 |
7 |
0.016
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.016
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.016
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.016
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.016
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.016
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.016
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.016
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.016
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.016
|
|
|
|
metanephric glomerular epithelial cell development
|
GO:0072313 |
2 |
0.016
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.016
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.016
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.016
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.016
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.016
|
|
|
|
positive regulation of humoral immune response
|
GO:0002922 |
11 |
0.016
|
|
|
|
purinergic nucleotide receptor signaling pathway
|
GO:0035590 |
3 |
0.016
|
|
|
|
regulation of mature b cell apoptotic process
|
GO:0002905 |
4 |
0.016
|
|
|
|
metanephric glomerular visceral epithelial cell development
|
GO:0072249 |
2 |
0.016
|
|
|
|
ruffle organization
|
GO:0031529 |
16 |
0.016
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.016
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.016
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.016
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.016
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.016
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.016
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.016
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.016
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.015
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.015
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.015
|
|
|
|
superoxide metabolic process
|
GO:0006801 |
27 |
0.015
|
|
|
|
monosaccharide biosynthetic process
|
GO:0046364 |
44 |
0.015
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.015
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.015
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.015
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.015
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.015
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.015
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.015
|
|
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
7 |
0.015
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.015
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.015
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.015
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.015
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.015
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.015
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.015
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.015
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.015
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.015
|
|
|
|
positive regulation of actin nucleation
|
GO:0051127 |
3 |
0.015
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.015
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.015
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.015
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.014
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.014
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.014
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.014
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.014
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.014
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.014
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.014
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.014
|
|
|
|
positive regulation of metanephric glomerulus development
|
GO:0072300 |
4 |
0.014
|
|
|
|
hexose biosynthetic process
|
GO:0019319 |
39 |
0.014
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.014
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.014
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.014
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.014
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.014
|
|
|
|
positive regulation of chemokine c x c motif ligand 2 production
|
GO:2000343 |
3 |
0.014
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.014
|
|
|
|
regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:1902165 |
8 |
0.014
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.014
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.014
|
|
|
|
microglia development
|
GO:0014005 |
2 |
0.014
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.014
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.014
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.014
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.014
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.014
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.014
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.014
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.014
|
|
