Mus musculus

0 known processes

Kpna3

karyopherin (importin) alpha 3

(Aliases: IPOA4)

Kpna3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein removal GO:0070646 21 0.925
protein modification by small protein conjugation or removal GO:0070647 207 0.603
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.571
protein catabolic process GO:0030163 221 0.469
proteasomal protein catabolic process GO:0010498 98 0.440
endoplasmic reticulum tubular network organization GO:0071786 1 0.333
regulation of cellular response to stress GO:0080135 159 0.324
lateral inhibition GO:0046331 1 0.313
synaptic transmission GO:0007268 329 0.295
regulation of protein transport GO:0051223 163 0.267
Fly
macromolecule catabolic process GO:0009057 281 0.229
cellular protein catabolic process GO:0044257 155 0.204
cellular macromolecule catabolic process GO:0044265 206 0.196
regulation of intracellular transport GO:0032386 159 0.187
Fly
modification dependent protein catabolic process GO:0019941 133 0.180
protein import GO:0017038 101 0.180
Mouse Fly
regulation of cell cycle GO:0051726 281 0.173
Fly
amp biosynthetic process GO:0006167 2 0.164
protein desumoylation GO:0016926 2 0.162
guanosine containing compound metabolic process GO:1901068 144 0.156
establishment of protein localization to organelle GO:0072594 118 0.153
Mouse Fly
regulation of protein catabolic process GO:0042176 108 0.152
ribonucleoprotein complex localization GO:0071166 1 0.152
chromosome segregation GO:0007059 48 0.144
protein polyubiquitination GO:0000209 33 0.139
intracellular protein transport GO:0006886 204 0.130
Mouse Fly
establishment of organelle localization GO:0051656 122 0.127
cellular amine metabolic process GO:0044106 44 0.124
protein localization to nucleus GO:0034504 121 0.121
Mouse Fly
organelle fission GO:0048285 170 0.119
purine ribonucleotide catabolic process GO:0009154 208 0.119
multicellular organismal protein catabolic process GO:0044254 1 0.117
positive regulation of intracellular transport GO:0032388 70 0.117
Fly
regulation of protein localization GO:0032880 231 0.109
Fly
positive regulation of cytoplasmic transport GO:1903651 40 0.106
Fly
ras protein signal transduction GO:0007265 77 0.106
regulation of nucleocytoplasmic transport GO:0046822 73 0.105
Fly
regulation of cellular catabolic process GO:0031329 242 0.105
protein localization to organelle GO:0033365 185 0.103
Mouse Fly
mitochondrion distribution GO:0048311 4 0.100
multicellular organismal macromolecule catabolic process GO:0044266 1 0.095
protein import into nucleus GO:0006606 95 0.093
Mouse Fly
purine containing compound catabolic process GO:0072523 213 0.091
protein modification by small protein conjugation GO:0032446 187 0.091
purine nucleoside triphosphate catabolic process GO:0009146 203 0.090
cellular amino acid metabolic process GO:0006520 103 0.090
single organism nuclear import GO:1902593 95 0.089
Mouse Fly
organelle localization GO:0051640 179 0.087
regulation of cytoplasmic transport GO:1903649 112 0.086
Fly
polyamine biosynthetic process GO:0006596 2 0.082
chromatin modification GO:0016568 187 0.081
protein targeting GO:0006605 143 0.081
Mouse Fly
meiotic cell cycle process GO:1903046 77 0.081
nuclear import GO:0051170 95 0.081
Mouse Fly
regulation of establishment of protein localization GO:0070201 181 0.078
Fly
nucleoside metabolic process GO:0009116 246 0.078
modification dependent macromolecule catabolic process GO:0043632 133 0.076
dendrite development GO:0016358 115 0.076
multicellular organismal protein metabolic process GO:0044268 2 0.076
response to organonitrogen compound GO:0010243 246 0.075
positive regulation of protein transport GO:0051222 93 0.074
Fly
cellular nitrogen compound catabolic process GO:0044270 280 0.073
regulation of apoptotic signaling pathway GO:2001233 197 0.069
positive regulation of protein localization to nucleus GO:1900182 30 0.068
Fly
compound eye development GO:0048749 1 0.068
cytoplasmic transport GO:0016482 234 0.065
Mouse Fly
positive regulation of protein import into nucleus GO:0042307 26 0.064
Fly
organic cyclic compound catabolic process GO:1901361 295 0.064
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.061
protein digestion GO:0044256 1 0.057
nucleoside catabolic process GO:0009164 206 0.057
ribose phosphate metabolic process GO:0019693 291 0.056
nucleocytoplasmic transport GO:0006913 139 0.055
Mouse Fly
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.055
organonitrogen compound catabolic process GO:1901565 264 0.055
stem cell differentiation GO:0048863 268 0.054
ribonucleoside triphosphate catabolic process GO:0009203 199 0.054
organophosphate catabolic process GO:0046434 232 0.053
organelle disassembly GO:1903008 2 0.052
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 1 0.051
nuclear transport GO:0051169 139 0.050
Mouse Fly
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.050
nucleoside triphosphate metabolic process GO:0009141 230 0.050
microtubule nucleation GO:0007020 2 0.050
dna replication GO:0006260 52 0.049
cellular response to dna damage stimulus GO:0006974 207 0.048
Fly
nucleoside phosphate metabolic process GO:0006753 338 0.046
purine nucleoside metabolic process GO:0042278 241 0.046
membrane organization GO:0061024 245 0.046
protein deubiquitination GO:0016579 19 0.044
nucleotide metabolic process GO:0009117 332 0.044
ribonucleotide catabolic process GO:0009261 208 0.044
aromatic compound catabolic process GO:0019439 286 0.044
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.043
spindle assembly involved in female meiosis i GO:0007057 2 0.043
ribonucleoside catabolic process GO:0042454 206 0.042
ribonucleoprotein complex disassembly GO:0032988 3 0.041
ubiquitin dependent protein catabolic process GO:0006511 129 0.041
meiotic nuclear division GO:0007126 115 0.040
cell cell signaling involved in cell fate commitment GO:0045168 35 0.040
chromatin organization GO:0006325 206 0.040
positive regulation of cellular catabolic process GO:0031331 148 0.039
regulation of organelle organization GO:0033043 289 0.039
purine containing compound metabolic process GO:0072521 311 0.039
establishment of meiotic spindle orientation GO:0051296 1 0.038
translation GO:0006412 93 0.038
mitotic cell cycle GO:0000278 195 0.038
Fly
rna interference GO:0016246 2 0.037
nucleotide catabolic process GO:0009166 217 0.037
protein complex disassembly GO:0043241 40 0.036
purine ribonucleotide metabolic process GO:0009150 290 0.035
erythrocyte differentiation GO:0030218 88 0.035
transmembrane transport GO:0055085 412 0.034
regulation of mapk cascade GO:0043408 248 0.034
response to transforming growth factor beta GO:0071559 88 0.034
purine nucleotide catabolic process GO:0006195 211 0.033
regulation of defense response GO:0031347 233 0.033
muscle cell differentiation GO:0042692 261 0.033
ribonucleotide metabolic process GO:0009259 291 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.033
maternal process involved in female pregnancy GO:0060135 32 0.032
regulation of mitotic cell cycle GO:0007346 126 0.032
Fly
mitotic nuclear division GO:0007067 48 0.032
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.032
cation transport GO:0006812 399 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.031
circulatory system process GO:0003013 197 0.031
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.031
cellular ketone metabolic process GO:0042180 84 0.031
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.030
protein localization to membrane GO:0072657 108 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
muscle tissue development GO:0060537 308 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.030
protein ubiquitination GO:0016567 171 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
regulation of cellular component biogenesis GO:0044087 181 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
striated muscle tissue development GO:0014706 293 0.028
spindle assembly involved in female meiosis GO:0007056 3 0.028
positive regulation of apoptotic signaling pathway GO:2001235 95 0.027
amine metabolic process GO:0009308 45 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
ribosome localization GO:0033750 1 0.027
misfolded protein transport GO:0070843 1 0.027
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.026
nuclear division GO:0000280 158 0.026
positive regulation of mitochondrial fission GO:0090141 2 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.026
regulation of protein targeting GO:1903533 61 0.026
Fly
regulation of cellular protein catabolic process GO:1903362 61 0.025
cajal body organization GO:0030576 1 0.025
macromolecular complex disassembly GO:0032984 43 0.025
negative regulation of defense response GO:0031348 77 0.025
lymphocyte differentiation GO:0030098 242 0.025
regulation of cell cycle process GO:0010564 160 0.024
Fly
cellular response to organonitrogen compound GO:0071417 145 0.024
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.024
heterocycle catabolic process GO:0046700 280 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
learning or memory GO:0007611 148 0.023
positive regulation of intracellular protein transport GO:0090316 42 0.023
Fly
cellular protein complex disassembly GO:0043624 36 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
positive regulation of proteolysis GO:0045862 85 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
positive regulation of cell cycle GO:0045787 92 0.022
regulation of protein complex assembly GO:0043254 83 0.021
bmp signaling pathway GO:0030509 93 0.021
polyamine transport GO:0015846 5 0.021
centrosome duplication GO:0051298 16 0.021
histone modification GO:0016570 159 0.021
regulation of proteolysis GO:0030162 164 0.021
multicellular organismal homeostasis GO:0048871 164 0.020
regulation of protein stability GO:0031647 52 0.020
skeletal muscle organ development GO:0060538 163 0.020
learning GO:0007612 98 0.020
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
regulation of intracellular protein transport GO:0033157 82 0.020
Fly
regulation of protein localization to nucleus GO:1900180 60 0.020
Fly
protein acylation GO:0043543 64 0.019
histone acetylation GO:0016573 41 0.019
regulation of neuron differentiation GO:0045664 281 0.019
ribonucleoside monophosphate metabolic process GO:0009161 80 0.019
ribosomal subunit export from nucleus GO:0000054 1 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
regulation of anatomical structure size GO:0090066 178 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
positive regulation of protein catabolic process GO:0045732 60 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
multi multicellular organism process GO:0044706 109 0.018
nitrogen compound transport GO:0071705 271 0.018
positive regulation of mitotic metaphase anaphase transition GO:0045842 2 0.018
mapk cascade GO:0000165 281 0.018
monoubiquitinated protein deubiquitination GO:0035520 2 0.017
labyrinthine layer blood vessel development GO:0060716 21 0.017
protein dna complex subunit organization GO:0071824 28 0.017
axonogenesis GO:0007409 274 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
regulation of mitosis GO:0007088 29 0.017
posttranslational protein targeting to membrane GO:0006620 2 0.017
pallium development GO:0021543 120 0.017
metaphase plate congression GO:0051310 2 0.016
dna repair GO:0006281 107 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
gene silencing by rna GO:0031047 19 0.016
gtp metabolic process GO:0046039 144 0.016
maintenance of location GO:0051235 89 0.016
establishment of protein localization to endoplasmic reticulum GO:0072599 2 0.015
centrosome separation GO:0051299 4 0.015
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.015
Fly
response to organic cyclic compound GO:0014070 198 0.015
positive regulation of cell development GO:0010720 237 0.015
ossification GO:0001503 216 0.015
response to growth factor GO:0070848 198 0.015
nucleus organization GO:0006997 45 0.015
nls bearing protein import into nucleus GO:0006607 2 0.015
protein oligomerization GO:0051259 67 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
ribonucleoside metabolic process GO:0009119 245 0.014
cellular response to peptide hormone stimulus GO:0071375 92 0.014
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.014
developmental maturation GO:0021700 193 0.014
central nervous system neuron development GO:0021954 67 0.014
endomembrane system organization GO:0010256 147 0.014
mitotic cell cycle process GO:1903047 159 0.014
Fly
regionalization GO:0003002 337 0.014
lysosomal transport GO:0007041 10 0.013
positive regulation of cell death GO:0010942 224 0.013
spermine metabolic process GO:0008215 3 0.013
er associated ubiquitin dependent protein catabolic process GO:0030433 10 0.013
negative regulation of organelle organization GO:0010639 90 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
dendritic spine development GO:0060996 30 0.013
rna 3 end processing GO:0031123 20 0.013
trophectodermal cellular morphogenesis GO:0001831 3 0.013
positive regulation of cellular protein catabolic process GO:1903364 34 0.013
homeostasis of number of cells GO:0048872 210 0.013
positive regulation of organelle organization GO:0010638 128 0.013
dendritic spine organization GO:0097061 26 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
oocyte axis specification GO:0007309 2 0.013
pyridine nucleotide biosynthetic process GO:0019363 4 0.013
hindbrain morphogenesis GO:0021575 46 0.013
cell maturation GO:0048469 127 0.013
lipid localization GO:0010876 126 0.013
positive regulation of chromosome organization GO:2001252 33 0.013
necroptotic process GO:0070266 21 0.013
regulation of hormone levels GO:0010817 211 0.013
response to alcohol GO:0097305 48 0.013
telencephalon development GO:0021537 186 0.013
dna endoreduplication GO:0042023 4 0.012
lymphocyte proliferation GO:0046651 164 0.012
negative regulation of immune system process GO:0002683 209 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
oocyte anterior posterior axis specification GO:0007314 2 0.012
hippocampus development GO:0021766 52 0.012
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.012
regulation of system process GO:0044057 200 0.012
dna metabolic process GO:0006259 303 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
regulation of mitochondrial fission GO:0090140 3 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
embryonic placenta development GO:0001892 98 0.012
copii coated vesicle budding GO:0090114 2 0.011
gtp catabolic process GO:0006184 143 0.011
spermatid differentiation GO:0048515 115 0.011
establishment of vesicle localization GO:0051650 81 0.011
regulation of protein oligomerization GO:0032459 4 0.011
forebrain development GO:0030900 302 0.011
cerebellum morphogenesis GO:0021587 42 0.011
amine biosynthetic process GO:0009309 3 0.011
adult behavior GO:0030534 135 0.011
cell aging GO:0007569 35 0.011
protein localization to cell leading edge GO:1902463 1 0.011
negative regulation of protein modification process GO:0031400 163 0.011
stem cell maintenance GO:0019827 130 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
response to amino acid GO:0043200 37 0.010
sensory perception GO:0007600 245 0.010
cell cycle switching GO:0060184 1 0.010
cellular homeostasis GO:0019725 240 0.010
oocyte maturation GO:0001556 18 0.010
histone h4 acetylation GO:0043967 10 0.010
rna processing GO:0006396 105 0.010
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.010
protein depolymerization GO:0051261 34 0.010
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.010
localization within membrane GO:0051668 4 0.010
nucleus localization GO:0051647 20 0.010
cellular biogenic amine metabolic process GO:0006576 28 0.010
regulation of synapse assembly GO:0051963 29 0.010
protein polymerization GO:0051258 57 0.010
innate immune response GO:0045087 157 0.010

Kpna3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.030
disease of anatomical entity DOID:7 0 0.030
neurodegenerative disease DOID:1289 0 0.030
nervous system disease DOID:863 0 0.030
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.020
retinal disease DOID:5679 0 0.014
eye disease DOID:5614 0 0.014