Mus musculus

0 known processes

Aftph

aftiphilin

(Aliases: AU018432,AU019184,9130023F12Rik,AU044244,AU016543,AU015099)

Aftph biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation or removal GO:0070647 207 0.100
small gtpase mediated signal transduction GO:0007264 97 0.072
protein modification by small protein conjugation GO:0032446 187 0.070
protein ubiquitination GO:0016567 171 0.045
negative regulation of molecular function GO:0044092 258 0.044
male gamete generation GO:0048232 285 0.044
negative regulation of protein metabolic process GO:0051248 282 0.042
ribose phosphate metabolic process GO:0019693 291 0.039
macromolecule catabolic process GO:0009057 281 0.038
amine metabolic process GO:0009308 45 0.038
nucleoside phosphate metabolic process GO:0006753 338 0.038
heterocycle catabolic process GO:0046700 280 0.038
regulation of organelle organization GO:0033043 289 0.037
ras protein signal transduction GO:0007265 77 0.037
purine containing compound metabolic process GO:0072521 311 0.037
nucleoside metabolic process GO:0009116 246 0.036
regulation of cellular component biogenesis GO:0044087 181 0.036
cellular amino acid metabolic process GO:0006520 103 0.036
cellular nitrogen compound catabolic process GO:0044270 280 0.036
cation transport GO:0006812 399 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
purine nucleoside triphosphate catabolic process GO:0009146 203 0.036
purine nucleoside metabolic process GO:0042278 241 0.035
spermatogenesis GO:0007283 284 0.034
covalent chromatin modification GO:0016569 163 0.033
cellular amine metabolic process GO:0044106 44 0.033
organic cyclic compound catabolic process GO:1901361 295 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.032
regulation of cellular catabolic process GO:0031329 242 0.032
ribonucleoside catabolic process GO:0042454 206 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
nucleoside phosphate catabolic process GO:1901292 222 0.031
cellular lipid metabolic process GO:0044255 323 0.031
transmembrane transport GO:0055085 412 0.030
purine containing compound catabolic process GO:0072523 213 0.030
protein catabolic process GO:0030163 221 0.030
endomembrane system organization GO:0010256 147 0.030
nucleoside triphosphate metabolic process GO:0009141 230 0.030
cellular ketone metabolic process GO:0042180 84 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
rho protein signal transduction GO:0007266 32 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.029
myeloid cell differentiation GO:0030099 233 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
nucleotide metabolic process GO:0009117 332 0.029
nucleoside catabolic process GO:0009164 206 0.029
homeostasis of number of cells GO:0048872 210 0.028
modification dependent protein catabolic process GO:0019941 133 0.028
membrane organization GO:0061024 245 0.028
ubiquitin dependent protein catabolic process GO:0006511 129 0.028
organonitrogen compound catabolic process GO:1901565 264 0.028
cytoplasmic transport GO:0016482 234 0.028
purine ribonucleoside metabolic process GO:0046128 241 0.028
ribonucleoside metabolic process GO:0009119 245 0.028
carbohydrate derivative catabolic process GO:1901136 231 0.028
cellular protein catabolic process GO:0044257 155 0.028
cytokine production GO:0001816 319 0.028
cellular macromolecule catabolic process GO:0044265 206 0.027
chromatin organization GO:0006325 206 0.027
glycosyl compound catabolic process GO:1901658 206 0.027
histone modification GO:0016570 159 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
posttranscriptional regulation of gene expression GO:0010608 155 0.027
nucleoside triphosphate catabolic process GO:0009143 205 0.027
epithelial tube morphogenesis GO:0060562 303 0.027
carbohydrate metabolic process GO:0005975 230 0.026
aromatic compound catabolic process GO:0019439 286 0.026
gland development GO:0048732 330 0.026
purine nucleoside catabolic process GO:0006152 205 0.026
regulation of cellular ketone metabolic process GO:0010565 66 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
regulation of purine nucleotide metabolic process GO:1900542 169 0.026
compound eye development GO:0048749 1 0.025
regulation of nucleoside metabolic process GO:0009118 130 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
apoptotic signaling pathway GO:0097190 306 0.025
cellular homeostasis GO:0019725 240 0.024
positive regulation of cellular catabolic process GO:0031331 148 0.024
protein maturation GO:0051604 176 0.024
immune effector process GO:0002252 321 0.024
methylation GO:0032259 134 0.024
organophosphate catabolic process GO:0046434 232 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
modification dependent macromolecule catabolic process GO:0043632 133 0.023
dna metabolic process GO:0006259 303 0.023
intracellular protein transport GO:0006886 204 0.023
regulation of vesicle mediated transport GO:0060627 139 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
cell type specific apoptotic process GO:0097285 268 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
regulation of cellular amino acid metabolic process GO:0006521 5 0.023
protein localization to organelle GO:0033365 185 0.023
nucleotide catabolic process GO:0009166 217 0.023
macromolecule methylation GO:0043414 120 0.023
regulation of ion transport GO:0043269 215 0.023
endocytosis GO:0006897 168 0.022
positive regulation of hydrolase activity GO:0051345 148 0.022
neuron apoptotic process GO:0051402 142 0.022
regulation of hydrolase activity GO:0051336 246 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
cell adhesion GO:0007155 329 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
microtubule based process GO:0007017 236 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
regulation of gtp catabolic process GO:0033124 113 0.020
protein targeting GO:0006605 143 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.020
regulation of transferase activity GO:0051338 263 0.020
cellular carbohydrate metabolic process GO:0044262 119 0.019
ion transmembrane transport GO:0034220 361 0.019
protein processing GO:0016485 163 0.019
peptidyl amino acid modification GO:0018193 336 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
positive regulation of protein modification process GO:0031401 299 0.019
neural tube development GO:0021915 160 0.019
chromatin modification GO:0016568 187 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
regulation of kinase activity GO:0043549 249 0.018
regulation of purine nucleotide catabolic process GO:0033121 122 0.018
synaptic transmission GO:0007268 329 0.018
regulation of ras gtpase activity GO:0032318 88 0.018
regulation of cell projection organization GO:0031344 206 0.018
organelle localization GO:0051640 179 0.018
protein polyubiquitination GO:0000209 33 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
nitrogen compound transport GO:0071705 271 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
negative regulation of protein modification process GO:0031400 163 0.018
neuronal action potential GO:0019228 54 0.018
cellular chemical homeostasis GO:0055082 215 0.018
positive regulation of cell death GO:0010942 224 0.017
leukocyte differentiation GO:0002521 342 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
neuron death GO:0070997 154 0.017
regulation of cell motility GO:2000145 236 0.017
dna repair GO:0006281 107 0.017
positive regulation of cell development GO:0010720 237 0.017
regulation of cytoskeleton organization GO:0051493 122 0.017
regulation of membrane potential GO:0042391 192 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
cellular response to lipid GO:0071396 145 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
actin filament organization GO:0007015 113 0.017
regulation of cytokine production GO:0001817 266 0.017
spermatid differentiation GO:0048515 115 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
epithelial cell development GO:0002064 159 0.017
cellular protein complex assembly GO:0043623 116 0.017
cation homeostasis GO:0055080 212 0.016
regulation of proteolysis GO:0030162 164 0.016
dephosphorylation GO:0016311 129 0.016
negative regulation of immune system process GO:0002683 209 0.016
regulation of transmembrane transport GO:0034762 128 0.016
response to organic cyclic compound GO:0014070 198 0.016
plasma membrane organization GO:0007009 90 0.016
mapk cascade GO:0000165 281 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
spermatid development GO:0007286 108 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
leukocyte mediated immunity GO:0002443 174 0.016
guanosine containing compound metabolic process GO:1901068 144 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.016
regulation of neuron differentiation GO:0045664 281 0.016
regulation of protein localization GO:0032880 231 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
multicellular organismal signaling GO:0035637 91 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
regulation of endocytosis GO:0030100 69 0.016
positive regulation of programmed cell death GO:0043068 218 0.015
regulation of hormone levels GO:0010817 211 0.015
glycerolipid metabolic process GO:0046486 122 0.015
guanosine containing compound catabolic process GO:1901069 144 0.015
divalent metal ion transport GO:0070838 172 0.015
transmission of nerve impulse GO:0019226 76 0.015
action potential GO:0001508 78 0.015
establishment of protein localization to organelle GO:0072594 118 0.015
metal ion homeostasis GO:0055065 189 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
calcium ion homeostasis GO:0055074 127 0.015
maintenance of location GO:0051235 89 0.015
lipid biosynthetic process GO:0008610 179 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
actin cytoskeleton organization GO:0030036 220 0.015
regulation of rho gtpase activity GO:0032319 58 0.015
germ cell development GO:0007281 185 0.015
protein localization to nucleus GO:0034504 121 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
cell division GO:0051301 120 0.015
wound healing GO:0042060 157 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
regulation of defense response GO:0031347 233 0.014
sequestering of calcium ion GO:0051208 18 0.014
establishment of organelle localization GO:0051656 122 0.014
neural tube formation GO:0001841 108 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
organelle fission GO:0048285 170 0.014
cellular ion homeostasis GO:0006873 165 0.014
regulation of cell adhesion GO:0030155 154 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
sensory perception GO:0007600 245 0.014
regulation of chromosome organization GO:0033044 83 0.014
regulation of cell migration GO:0030334 219 0.014
sequestering of metal ion GO:0051238 19 0.014
regulation of intracellular transport GO:0032386 159 0.014
calcium ion transport GO:0006816 159 0.014
negative regulation of nervous system development GO:0051961 156 0.014
negative regulation of organelle organization GO:0010639 90 0.014
regulation of secretion GO:0051046 274 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
regulation of neuron death GO:1901214 134 0.014
vesicle organization GO:0016050 60 0.014
cation transmembrane transport GO:0098655 266 0.014
response to organonitrogen compound GO:0010243 246 0.013
positive regulation of cytokine production GO:0001819 174 0.013
positive regulation of transferase activity GO:0051347 167 0.013
gtp catabolic process GO:0006184 143 0.013
rhythmic process GO:0048511 174 0.013
positive regulation of gtpase activity GO:0043547 85 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
oxidation reduction process GO:0055114 342 0.013
innate immune response GO:0045087 157 0.013
gtp metabolic process GO:0046039 144 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
ossification GO:0001503 216 0.013
positive regulation of organelle organization GO:0010638 128 0.013
leukocyte proliferation GO:0070661 172 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
epithelial tube formation GO:0072175 130 0.013
tube formation GO:0035148 140 0.013
sensory organ morphogenesis GO:0090596 242 0.013
response to growth factor GO:0070848 198 0.013
negative regulation of neuron death GO:1901215 98 0.013
regulation of cellular component size GO:0032535 121 0.013
phospholipid metabolic process GO:0006644 87 0.013
developmental maturation GO:0021700 193 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
organelle assembly GO:0070925 177 0.012
tissue homeostasis GO:0001894 115 0.012
divalent inorganic cation transport GO:0072511 178 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
regulation of t cell activation GO:0050863 170 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
regulation of protein maturation GO:1903317 96 0.012
response to lipopolysaccharide GO:0032496 128 0.012
nuclear division GO:0000280 158 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
digestive system development GO:0055123 200 0.012
regulation of response to wounding GO:1903034 189 0.012
wnt signaling pathway GO:0016055 188 0.012
axonogenesis GO:0007409 274 0.012
anion transport GO:0006820 177 0.012
anatomical structure homeostasis GO:0060249 145 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
regulation of actin filament based process GO:0032970 99 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
b cell activation GO:0042113 161 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
defense response to other organism GO:0098542 197 0.012
inflammatory response GO:0006954 244 0.012
muscle system process GO:0003012 141 0.012
protein polymerization GO:0051258 57 0.012
blood vessel morphogenesis GO:0048514 285 0.012
respiratory tube development GO:0030323 167 0.012
muscle cell differentiation GO:0042692 261 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.012
response to oxidative stress GO:0006979 123 0.012
small molecule biosynthetic process GO:0044283 132 0.012
chemotaxis GO:0006935 247 0.011
glycoprotein metabolic process GO:0009100 116 0.011
mitotic cell cycle GO:0000278 195 0.011
fat cell differentiation GO:0045444 160 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
regulation of multi organism process GO:0043900 111 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
development of primary sexual characteristics GO:0045137 143 0.011
skeletal system development GO:0001501 356 0.011
respiratory system development GO:0060541 190 0.011
ear development GO:0043583 200 0.011
muscle tissue development GO:0060537 308 0.011
cell activation involved in immune response GO:0002263 126 0.011
regulation of protein kinase activity GO:0045859 232 0.011
positive regulation of ras gtpase activity GO:0032320 65 0.011
cognition GO:0050890 149 0.011
heart morphogenesis GO:0003007 178 0.011
mitotic cell cycle process GO:1903047 159 0.011
regulation of cell cycle process GO:0010564 160 0.011
regulation of protein processing GO:0070613 96 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
regulation of secretion by cell GO:1903530 249 0.011
vesicle localization GO:0051648 86 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
regulation of protein complex assembly GO:0043254 83 0.011
t cell activation GO:0042110 289 0.011
synapse organization GO:0050808 125 0.011
locomotory behavior GO:0007626 195 0.011
renal system development GO:0072001 225 0.011
apical constriction GO:0003383 4 0.011
regulation of cell activation GO:0050865 289 0.011
epithelial cell proliferation GO:0050673 174 0.011
male sex differentiation GO:0046661 109 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
lymphocyte differentiation GO:0030098 242 0.011
mitochondrion organization GO:0007005 134 0.011
lipid localization GO:0010876 126 0.011
actin filament based movement GO:0030048 23 0.011
gonad development GO:0008406 141 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
regulation of protein catabolic process GO:0042176 108 0.011
regulation of rho protein signal transduction GO:0035023 71 0.011
positive regulation of kinase activity GO:0033674 155 0.010
cytokinetic process GO:0032506 2 0.010
regulation of homeostatic process GO:0032844 182 0.010
urogenital system development GO:0001655 261 0.010
response to inorganic substance GO:0010035 96 0.010
positive regulation of nervous system development GO:0051962 221 0.010
lateral inhibition GO:0046331 1 0.010
regulation of anatomical structure size GO:0090066 178 0.010
fertilization GO:0009566 127 0.010
regulation of cell cycle GO:0051726 281 0.010
positive regulation of proteolysis GO:0045862 85 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
establishment of vesicle localization GO:0051650 81 0.010
angiogenesis GO:0001525 201 0.010
negative regulation of neuron apoptotic process GO:0043524 92 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
macromolecule glycosylation GO:0043413 55 0.010
limb development GO:0060173 166 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
response to peptide GO:1901652 136 0.010
negative regulation of protein maturation GO:1903318 79 0.010
regulation of protein transport GO:0051223 163 0.010
synaptic vesicle localization GO:0097479 59 0.010
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
translation GO:0006412 93 0.010
activation of immune response GO:0002253 138 0.010

Aftph disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022
bone disease DOID:0080001 0 0.014
disease of anatomical entity DOID:7 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
nervous system disease DOID:863 0 0.013