Mus musculus

0 known processes

Nalcn

sodium leak channel, non-selective

(Aliases: A530023G15Rik,Vgcnl1,AI849508)

Nalcn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 329 0.131
Worm
locomotory behavior GO:0007626 195 0.080
Fly
positive regulation of nervous system development GO:0051962 221 0.067
regulation of neuron projection development GO:0010975 169 0.065
membrane organization GO:0061024 245 0.060
transmembrane transport GO:0055085 412 0.060
Fly
positive regulation of cell development GO:0010720 237 0.060
regulation of neuron differentiation GO:0045664 281 0.055
regulation of membrane potential GO:0042391 192 0.053
ion transmembrane transport GO:0034220 361 0.048
Fly
action potential GO:0001508 78 0.047
g protein coupled receptor signaling pathway GO:0007186 243 0.046
neuronal action potential GO:0019228 54 0.046
multicellular organismal signaling GO:0035637 91 0.046
positive regulation of neuron differentiation GO:0045666 141 0.044
inorganic ion transmembrane transport GO:0098660 234 0.044
telencephalon development GO:0021537 186 0.043
cellular amino acid metabolic process GO:0006520 103 0.041
regulation of hormone levels GO:0010817 211 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.040
forebrain development GO:0030900 302 0.039
adult behavior GO:0030534 135 0.038
Fly
sensory perception GO:0007600 245 0.038
Fly
cognition GO:0050890 149 0.037
regulation of protein kinase activity GO:0045859 232 0.036
cation transport GO:0006812 399 0.033
Fly
gliogenesis GO:0042063 141 0.032
axonogenesis GO:0007409 274 0.031
regulation of system process GO:0044057 200 0.031
spermatogenesis GO:0007283 284 0.029
sensory organ morphogenesis GO:0090596 242 0.028
camera type eye development GO:0043010 266 0.028
cation transmembrane transport GO:0098655 266 0.028
Fly
nitrogen compound transport GO:0071705 271 0.028
cellular lipid metabolic process GO:0044255 323 0.028
learning or memory GO:0007611 148 0.028
striated muscle tissue development GO:0014706 293 0.028
cell adhesion GO:0007155 329 0.028
cation homeostasis GO:0055080 212 0.027
myelination GO:0042552 74 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
transmission of nerve impulse GO:0019226 76 0.027
glial cell differentiation GO:0010001 131 0.027
negative regulation of cell proliferation GO:0008285 296 0.026
microtubule based process GO:0007017 236 0.026
regulation of organelle organization GO:0033043 289 0.026
positive regulation of cell projection organization GO:0031346 95 0.026
regulation of cellular amino acid metabolic process GO:0006521 5 0.025
amine metabolic process GO:0009308 45 0.025
cell type specific apoptotic process GO:0097285 268 0.025
cellular ketone metabolic process GO:0042180 84 0.025
positive regulation of protein modification process GO:0031401 299 0.025
regulation of cell projection organization GO:0031344 206 0.024
metal ion homeostasis GO:0055065 189 0.024
multicellular organism growth GO:0035264 161 0.023
cellular amine metabolic process GO:0044106 44 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
male gamete generation GO:0048232 285 0.023
macromolecule catabolic process GO:0009057 281 0.023
learning GO:0007612 98 0.022
peptidyl amino acid modification GO:0018193 336 0.022
mapk cascade GO:0000165 281 0.022
single organism cell adhesion GO:0098602 156 0.022
nucleotide metabolic process GO:0009117 332 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
engulfment of apoptotic cell GO:0043652 3 0.022
central nervous system neuron differentiation GO:0021953 162 0.022
dna metabolic process GO:0006259 303 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
neuromuscular process GO:0050905 99 0.021
organelle fission GO:0048285 170 0.021
regulation of ion transport GO:0043269 215 0.021
rhythmic process GO:0048511 174 0.021
Fly
synapse organization GO:0050808 125 0.021
positive regulation of neuron projection development GO:0010976 79 0.021
compound eye development GO:0048749 1 0.020
memory GO:0007613 58 0.020
ensheathment of neurons GO:0007272 76 0.020
activation of mapkkk activity GO:0000185 1 0.020
regulation of kinase activity GO:0043549 249 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.020
regulation of transferase activity GO:0051338 263 0.020
ear development GO:0043583 200 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
sa node cell action potential GO:0086015 4 0.019
muscle tissue development GO:0060537 308 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
regulation of peptide secretion GO:0002791 77 0.019
negative regulation of nervous system development GO:0051961 156 0.019
dendrite development GO:0016358 115 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
nuclear division GO:0000280 158 0.019
regulation of secretion by cell GO:1903530 249 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
hormone secretion GO:0046879 128 0.019
ribonucleotide metabolic process GO:0009259 291 0.018
regulation of neurotransmitter levels GO:0001505 87 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
actin filament organization GO:0007015 113 0.018
regulation of hormone secretion GO:0046883 88 0.018
cytokinetic process GO:0032506 2 0.018
neuron migration GO:0001764 122 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
cytoplasmic transport GO:0016482 234 0.018
reflex GO:0060004 22 0.018
dephosphorylation GO:0016311 129 0.018
defecation GO:0030421 1 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
cellular homeostasis GO:0019725 240 0.017
protein localization to organelle GO:0033365 185 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
germ cell development GO:0007281 185 0.017
sensory perception of sound GO:0007605 97 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
cellular protein complex assembly GO:0043623 116 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
intracellular protein transport GO:0006886 204 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
wnt signaling pathway GO:0016055 188 0.017
protein ubiquitination GO:0016567 171 0.017
associative learning GO:0008306 61 0.017
response to organonitrogen compound GO:0010243 246 0.016
positive regulation of transferase activity GO:0051347 167 0.016
regulation of neuron death GO:1901214 134 0.016
neurotransmitter transport GO:0006836 76 0.016
peptide secretion GO:0002790 114 0.016
axon ensheathment GO:0008366 76 0.016
olfactory learning GO:0008355 2 0.016
negative regulation of cell development GO:0010721 169 0.016
divalent inorganic cation transport GO:0072511 178 0.016
adult locomotory behavior GO:0008344 91 0.016
Fly
regulation of transmembrane transport GO:0034762 128 0.016
endocytosis GO:0006897 168 0.016
regulation of secretion GO:0051046 274 0.016
stem cell differentiation GO:0048863 268 0.016
positive regulation of kinase activity GO:0033674 155 0.016
cellular macromolecule catabolic process GO:0044265 206 0.015
epidermis development GO:0008544 187 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
apoptotic signaling pathway GO:0097190 306 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
response to organic cyclic compound GO:0014070 198 0.015
regulation of anatomical structure size GO:0090066 178 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
cardiac muscle cell contraction GO:0086003 7 0.015
peptide hormone secretion GO:0030072 109 0.015
exocytosis GO:0006887 121 0.015
muscle cell differentiation GO:0042692 261 0.015
cellular chemical homeostasis GO:0055082 215 0.015
regulation of proteolysis GO:0030162 164 0.015
regulation of metal ion transport GO:0010959 106 0.015
regulation of peptide transport GO:0090087 91 0.015
organic cyclic compound catabolic process GO:1901361 295 0.014
organic hydroxy compound transport GO:0015850 93 0.014
heterocycle catabolic process GO:0046700 280 0.014
aromatic compound catabolic process GO:0019439 286 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
gland development GO:0048732 330 0.014
calcium ion homeostasis GO:0055074 127 0.014
rna processing GO:0006396 105 0.014
skeletal system development GO:0001501 356 0.014
cell substrate adhesion GO:0031589 130 0.014
regulation of peptide hormone secretion GO:0090276 75 0.014
carbohydrate homeostasis GO:0033500 128 0.014
cellular ion homeostasis GO:0006873 165 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
oxidation reduction process GO:0055114 342 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
hindbrain development GO:0030902 128 0.014
muscle contraction GO:0006936 101 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
response to radiation GO:0009314 165 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
oligodendrocyte development GO:0014003 20 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
neural precursor cell proliferation GO:0061351 121 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
mrna metabolic process GO:0016071 84 0.014
divalent metal ion transport GO:0070838 172 0.014
response to acid chemical GO:0001101 111 0.014
regulation of actin filament based process GO:0032970 99 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
lipid transport GO:0006869 98 0.013
regulation of hydrolase activity GO:0051336 246 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
regulation of cell cycle GO:0051726 281 0.013
protein catabolic process GO:0030163 221 0.013
extracellular matrix organization GO:0030198 147 0.013
muscle system process GO:0003012 141 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
regulation of neuronal synaptic plasticity GO:0048168 30 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
photoreceptor cell differentiation GO:0046530 52 0.013
endomembrane system organization GO:0010256 147 0.013
establishment of organelle localization GO:0051656 122 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.012
organ growth GO:0035265 117 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
oligodendrocyte differentiation GO:0048709 53 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
lung development GO:0030324 164 0.012
regulation of blood circulation GO:1903522 93 0.012
spermatid development GO:0007286 108 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
positive regulation of map kinase activity GO:0043406 84 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
negative regulation of protein metabolic process GO:0051248 282 0.012
regulation of map kinase activity GO:0043405 120 0.012
t cell activation GO:0042110 289 0.012
nerve development GO:0021675 67 0.012
renal system development GO:0072001 225 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
chromatin organization GO:0006325 206 0.012
potassium ion transmembrane transport GO:0071805 43 0.012
positive regulation of cell death GO:0010942 224 0.012
cellularization GO:0007349 1 0.012
positive regulation of ion transport GO:0043270 65 0.012
regulation of glial cell differentiation GO:0045685 41 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
epithelial cell development GO:0002064 159 0.012
cell proliferation in hindbrain GO:0021534 10 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
mrna processing GO:0006397 63 0.012
skeletal muscle organ development GO:0060538 163 0.012
fat cell differentiation GO:0045444 160 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
regulation of homeostatic process GO:0032844 182 0.012
peptide transport GO:0015833 133 0.012
methylation GO:0032259 134 0.012
glycosyl compound metabolic process GO:1901657 246 0.011
blood circulation GO:0008015 195 0.011
histone modification GO:0016570 159 0.011
regulation of mapk cascade GO:0043408 248 0.011
purine containing compound metabolic process GO:0072521 311 0.011
response to osmotic stress GO:0006970 21 0.011
stem cell proliferation GO:0072089 117 0.011
protein targeting GO:0006605 143 0.011
insulin secretion GO:0030073 89 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
positive regulation of protein export from nucleus GO:0046827 4 0.011
regulation of cell adhesion GO:0030155 154 0.011
neuron death GO:0070997 154 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
regulation of exocytosis GO:0017157 61 0.011
regulation of cell migration GO:0030334 219 0.011
actin filament polymerization GO:0030041 44 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
regulation of feeding behavior GO:0060259 3 0.011
cellular protein catabolic process GO:0044257 155 0.011
lipid localization GO:0010876 126 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
regulation of muscle system process GO:0090257 80 0.011
organelle assembly GO:0070925 177 0.011
respiratory system development GO:0060541 190 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
chromatin modification GO:0016568 187 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
extracellular structure organization GO:0043062 148 0.011
synapse assembly GO:0007416 56 0.011
negative regulation of molecular function GO:0044092 258 0.011
oocyte axis specification GO:0007309 2 0.011
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.011
carbohydrate metabolic process GO:0005975 230 0.011
multicellular organismal response to stress GO:0033555 62 0.011
protein localization to membrane GO:0072657 108 0.011
oocyte construction GO:0007308 2 0.011
muscle cell development GO:0055001 133 0.011
regulation of cell motility GO:2000145 236 0.011
asymmetric stem cell division GO:0098722 3 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
oocyte anterior posterior axis specification GO:0007314 2 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.010
negative regulation of cellular protein metabolic process GO:0032269 247 0.010
positive regulation of secretion GO:0051047 130 0.010
actin cytoskeleton organization GO:0030036 220 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
stem cell maintenance GO:0019827 130 0.010
wound healing GO:0042060 157 0.010
mitotic cell cycle GO:0000278 195 0.010
phenol containing compound metabolic process GO:0018958 60 0.010
ossification GO:0001503 216 0.010
hormone metabolic process GO:0042445 86 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
cranial nerve development GO:0021545 41 0.010
regulation of intracellular transport GO:0032386 159 0.010
negative regulation of bone trabecula formation GO:1900155 1 0.010
positive regulation of organelle organization GO:0010638 128 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
lymphocyte differentiation GO:0030098 242 0.010
striated muscle cell development GO:0055002 125 0.010
skin development GO:0043588 220 0.010

Nalcn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.044
disease of anatomical entity DOID:7 0 0.044
central nervous system disease DOID:331 0 0.028
disease of mental health DOID:150 0 0.019
non syndromic intellectual disability DOID:0050889 0 0.019
developmental disorder of mental health DOID:0060037 0 0.019
intellectual disability DOID:1059 0 0.019
specific developmental disorder DOID:0060038 0 0.019
brain disease DOID:936 0 0.017
sensory system disease DOID:0050155 0 0.015
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.011
retinal disease DOID:5679 0 0.011
eye disease DOID:5614 0 0.011
retinal degeneration DOID:8466 0 0.011
eye and adnexa disease DOID:1492 0 0.011