Mus musculus

300 known processes

Slc11a1

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

(Aliases: Nramp1,MGC129156,MGC129157,ity,Bcg,Ity,Lsh,Nramp)

Slc11a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune effector process GO:0002252 321 0.824
regulation of cytokine production GO:0001817 266 0.818
regulation of inflammatory response GO:0050727 147 0.782
cytokine production GO:0001816 319 0.715
inflammatory response GO:0006954 244 0.714
regulation of cell activation GO:0050865 289 0.697
defense response to other organism GO:0098542 197 0.662
cell chemotaxis GO:0060326 81 0.614
regulation of defense response GO:0031347 233 0.576
leukocyte mediated immunity GO:0002443 174 0.573
cellular response to lipopolysaccharide GO:0071222 77 0.570
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.570
t cell activation GO:0042110 289 0.566
toll like receptor 9 signaling pathway GO:0034162 6 0.544
chemotaxis GO:0006935 247 0.540
leukocyte activation involved in immune response GO:0002366 126 0.537
positive regulation of cytokine secretion GO:0050715 41 0.535
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.512
cellular response to molecule of bacterial origin GO:0071219 83 0.496
regulation of secretion GO:0051046 274 0.493
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.490
regulation of lymphocyte activation GO:0051249 240 0.483
adaptive immune response GO:0002250 155 0.464
positive regulation of cytokine production GO:0001819 174 0.442
positive regulation of macrophage chemotaxis GO:0010759 5 0.437
negative regulation of cell proliferation GO:0008285 296 0.428
regulation of response to wounding GO:1903034 189 0.410
regulation of protein serine threonine kinase activity GO:0071900 157 0.402
regulation of protein secretion GO:0050708 82 0.399
positive regulation of phagocytosis GO:0050766 26 0.396
response to molecule of bacterial origin GO:0002237 143 0.395
cytokine secretion GO:0050663 72 0.389
innate immune response GO:0045087 157 0.380
activation of immune response GO:0002253 138 0.358
regulation of cytokine secretion GO:0050707 61 0.357
leukocyte differentiation GO:0002521 342 0.344
defense response to bacterium GO:0042742 119 0.342
regulation of leukocyte proliferation GO:0070663 121 0.329
positive regulation of cell migration GO:0030335 109 0.325
myeloid leukocyte activation GO:0002274 83 0.314
negative regulation of immune system process GO:0002683 209 0.305
neutrophil chemotaxis GO:0030593 36 0.301
regulation of cell motility GO:2000145 236 0.298
positive regulation of protein phosphorylation GO:0001934 242 0.296
leukocyte migration GO:0050900 124 0.295
toll like receptor signaling pathway GO:0002224 38 0.293
immunoglobulin mediated immune response GO:0016064 69 0.292
response to lipopolysaccharide GO:0032496 128 0.287
positive regulation of immune effector process GO:0002699 107 0.277
adiponectin secretion GO:0070162 2 0.274
positive regulation of inflammatory response GO:0050729 47 0.274
protein secretion GO:0009306 111 0.272
neutrophil migration GO:1990266 37 0.259
positive regulation of cell activation GO:0050867 158 0.258
positive regulation of cell motility GO:2000147 116 0.257
leukocyte proliferation GO:0070661 172 0.257
regulation of natural killer cell chemotaxis GO:2000501 1 0.257
regulation of t cell activation GO:0050863 170 0.256
angiogenesis GO:0001525 201 0.254
eosinophil migration GO:0072677 3 0.251
cellular response to cytokine stimulus GO:0071345 189 0.250
positive regulation of endocytosis GO:0045807 42 0.249
t cell activation involved in immune response GO:0002286 43 0.240
regulation of lymphocyte proliferation GO:0050670 117 0.233
reactive oxygen species metabolic process GO:0072593 84 0.228
leukocyte chemotaxis GO:0030595 69 0.226
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.223
thymocyte migration GO:0072679 2 0.222
immune response activating signal transduction GO:0002757 116 0.222
positive regulation of kinase activity GO:0033674 155 0.215
immune response regulating signaling pathway GO:0002764 125 0.214
regulation of leukocyte mediated immunity GO:0002703 104 0.212
granulocyte migration GO:0097530 43 0.211
regulation of cell migration GO:0030334 219 0.205
innate immune response activating signal transduction GO:0002758 50 0.202
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.199
lymphocyte differentiation GO:0030098 242 0.193
cellular response to biotic stimulus GO:0071216 92 0.188
cell adhesion GO:0007155 329 0.187
positive regulation of eosinophil migration GO:2000418 2 0.187
regulation of vesicle mediated transport GO:0060627 139 0.187
cell activation involved in immune response GO:0002263 126 0.183
t cell differentiation GO:0030217 174 0.181
positive regulation of monocyte chemotaxis GO:0090026 2 0.179
positive regulation of apoptotic process GO:0043065 217 0.179
positive regulation of protein secretion GO:0050714 52 0.177
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.177
regulation of secretion by cell GO:1903530 249 0.176
homeostasis of number of cells GO:0048872 210 0.174
Mouse
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.171
regulation of map kinase activity GO:0043405 120 0.169
cellular ketone metabolic process GO:0042180 84 0.166
production of molecular mediator of immune response GO:0002440 103 0.166
myeloid leukocyte migration GO:0097529 57 0.164
myeloid cell differentiation GO:0030099 233 0.163
Mouse
amine metabolic process GO:0009308 45 0.163
b cell mediated immunity GO:0019724 71 0.162
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.160
positive regulation of lymphocyte activation GO:0051251 140 0.157
cellular amino acid metabolic process GO:0006520 103 0.155
response to organonitrogen compound GO:0010243 246 0.154
phagocytosis GO:0006909 66 0.149
regulation of t cell proliferation GO:0042129 92 0.149
lymphocyte mediated immunity GO:0002449 139 0.148
negative regulation of mast cell degranulation GO:0043305 4 0.145
positive regulation of defense response GO:0031349 124 0.142
cellular chemical homeostasis GO:0055082 215 0.142
myeloid leukocyte mediated immunity GO:0002444 42 0.138
sequestering of metal ion GO:0051238 19 0.138
positive regulation of programmed cell death GO:0043068 218 0.136
cellular response to lipid GO:0071396 145 0.135
leukocyte homeostasis GO:0001776 79 0.133
regulation of leukocyte apoptotic process GO:2000106 56 0.131
positive regulation of chemotaxis GO:0050921 38 0.131
cytosolic calcium ion homeostasis GO:0051480 70 0.129
positive regulation of leukocyte mediated immunity GO:0002705 70 0.127
regulation of innate immune response GO:0045088 91 0.125
cellular response to peptidoglycan GO:0071224 4 0.124
regulation of hormone levels GO:0010817 211 0.121
response to peptide GO:1901652 136 0.120
positive regulation of protein kinase b signaling GO:0051897 32 0.119
acute inflammatory response GO:0002526 41 0.116
mast cell degranulation GO:0043303 19 0.116
activation of innate immune response GO:0002218 56 0.115
negative regulation of protein metabolic process GO:0051248 282 0.114
positive regulation of leukocyte differentiation GO:1902107 86 0.113
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.113
regulation of endocytosis GO:0030100 69 0.111
calcium mediated signaling GO:0019722 46 0.110
positive regulation of secretion by cell GO:1903532 114 0.108
cytokine metabolic process GO:0042107 71 0.107
regulation of protein transport GO:0051223 163 0.106
cation transport GO:0006812 399 0.105
negative regulation of map kinase activity GO:0043407 34 0.103
myeloid leukocyte differentiation GO:0002573 119 0.103
regulation of protein localization GO:0032880 231 0.103
regulation of cellular amine metabolic process GO:0033238 20 0.103
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.101
t cell proliferation GO:0042098 120 0.101
positive regulation of secretion GO:0051047 130 0.099
alpha beta t cell activation GO:0046631 91 0.099
protein kinase b signaling GO:0043491 74 0.099
regulation of homeostatic process GO:0032844 182 0.099
cellular homeostasis GO:0019725 240 0.098
regulation of thymocyte migration GO:2000410 2 0.098
regulation of monocyte chemotaxis GO:0090025 3 0.098
positive regulation of t cell activation GO:0050870 101 0.097
detection of stimulus GO:0051606 84 0.096
muscle cell differentiation GO:0042692 261 0.095
pattern recognition receptor signaling pathway GO:0002221 47 0.095
second messenger mediated signaling GO:0019932 73 0.095
regulation of mapk cascade GO:0043408 248 0.094
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.093
regulation of cellular ketone metabolic process GO:0010565 66 0.092
endocytosis GO:0006897 168 0.091
b cell activation GO:0042113 161 0.091
regulation of adaptive immune response GO:0002819 90 0.091
regulation of chemokine production GO:0032642 30 0.090
g protein coupled receptor signaling pathway GO:0007186 243 0.090
negative regulation of serotonin secretion GO:0014063 2 0.090
serotonin secretion by mast cell GO:0002552 1 0.090
positive regulation of cellular amine metabolic process GO:0033240 5 0.089
regulation of establishment of protein localization GO:0070201 181 0.089
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.088
regulation of kinase activity GO:0043549 249 0.088
activation of mapk activity GO:0000187 59 0.088
regulation of system process GO:0044057 200 0.088
regulation of mast cell activation GO:0033003 21 0.087
negative regulation of cell activation GO:0050866 111 0.087
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.087
regulation of protein kinase activity GO:0045859 232 0.085
granulocyte chemotaxis GO:0071621 39 0.084
positive regulation of leukocyte proliferation GO:0070665 73 0.082
positive regulation of lymphocyte differentiation GO:0045621 61 0.081
mapk cascade GO:0000165 281 0.080
negative regulation of leukocyte proliferation GO:0070664 46 0.080
negative regulation of t cell activation GO:0050868 65 0.080
lymphocyte activation involved in immune response GO:0002285 93 0.079
glial cell differentiation GO:0010001 131 0.079
negative regulation of phosphorus metabolic process GO:0010563 184 0.079
negative regulation of lymphocyte activation GO:0051250 91 0.078
positive regulation of t cell differentiation GO:0045582 52 0.076
calcium ion transport GO:0006816 159 0.076
cellular calcium ion homeostasis GO:0006874 119 0.076
regulation of lymphocyte differentiation GO:0045619 107 0.075
regulation of mast cell activation involved in immune response GO:0033006 17 0.074
leukocyte apoptotic process GO:0071887 71 0.074
negative regulation of protein modification process GO:0031400 163 0.074
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.074
cellular metal ion homeostasis GO:0006875 151 0.073
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.073
purinergic receptor signaling pathway GO:0035587 7 0.073
positive regulation of behavior GO:0048520 40 0.072
regulation of vasculature development GO:1901342 88 0.072
mast cell activation involved in immune response GO:0002279 20 0.072
positive regulation of homeostatic process GO:0032846 64 0.071
regulation of epithelial cell proliferation GO:0050678 141 0.071
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.071
regulation of ion transport GO:0043269 215 0.071
positive regulation of innate immune response GO:0045089 80 0.070
regulation of toll like receptor signaling pathway GO:0034121 20 0.070
extracellular structure organization GO:0043062 148 0.070
chemokine production GO:0032602 34 0.069
regulation of type iia hypersensitivity GO:0001796 4 0.069
positive regulation of map kinase activity GO:0043406 84 0.068
erythrocyte differentiation GO:0030218 88 0.068
Mouse
blood vessel morphogenesis GO:0048514 285 0.067
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045425 2 0.067
t helper cell differentiation GO:0042093 28 0.066
positive regulation of protein transport GO:0051222 93 0.066
humoral immune response GO:0006959 57 0.066
divalent inorganic cation homeostasis GO:0072507 138 0.066
single organism cell adhesion GO:0098602 156 0.065
nucleobase containing small molecule metabolic process GO:0055086 352 0.065
cellular amine metabolic process GO:0044106 44 0.065
regulation of angiogenesis GO:0045765 81 0.065
regulation of intracellular transport GO:0032386 159 0.065
regulation of leukocyte differentiation GO:1902105 159 0.064
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.064
positive regulation of neutrophil migration GO:1902624 12 0.063
peptidyl amino acid modification GO:0018193 336 0.063
positive regulation of leukocyte degranulation GO:0043302 10 0.063
fc epsilon receptor signaling pathway GO:0038095 3 0.063
toll like receptor 7 signaling pathway GO:0034154 4 0.062
reactive oxygen species biosynthetic process GO:1903409 8 0.062
negative regulation of t cell proliferation GO:0042130 38 0.061
mast cell activation GO:0045576 27 0.061
defense response to virus GO:0051607 68 0.061
small gtpase mediated signal transduction GO:0007264 97 0.061
cellular response to organonitrogen compound GO:0071417 145 0.061
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.061
blood circulation GO:0008015 195 0.060
dendritic cell differentiation GO:0097028 26 0.060
skeletal system development GO:0001501 356 0.060
circulatory system process GO:0003013 197 0.059
cellular response to peptide hormone stimulus GO:0071375 92 0.059
negative regulation of phosphorylation GO:0042326 166 0.059
regulation of protein kinase b signaling GO:0051896 56 0.059
fat cell differentiation GO:0045444 160 0.059
cellular response to interferon gamma GO:0071346 25 0.059
response to organic cyclic compound GO:0014070 198 0.058
positive regulation of response to wounding GO:1903036 66 0.058
regulation of cellular amino acid metabolic process GO:0006521 5 0.058
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.057
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.057
organelle localization GO:0051640 179 0.057
tumor necrosis factor production GO:0032640 50 0.056
glucose transport GO:0015758 56 0.056
negative regulation of phosphate metabolic process GO:0045936 184 0.056
immunoglobulin production GO:0002377 73 0.056
regulation of b cell chemotaxis GO:2000537 2 0.055
positive regulation of protein modification process GO:0031401 299 0.055
metal ion homeostasis GO:0055065 189 0.055
phosphatidylinositol mediated signaling GO:0048015 41 0.055
negative regulation of cytokine production GO:0001818 84 0.055
regulation of t cell differentiation GO:0045580 83 0.055
cellular response to insulin stimulus GO:0032869 78 0.055
multicellular organismal homeostasis GO:0048871 164 0.054
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.054
gland development GO:0048732 330 0.054
positive regulation of cell death GO:0010942 224 0.054
positive regulation of calcium mediated signaling GO:0050850 15 0.053
cell type specific apoptotic process GO:0097285 268 0.053
exocytosis GO:0006887 121 0.053
regulation of fat cell differentiation GO:0045598 81 0.053
sequestering of calcium ion GO:0051208 18 0.053
mast cell mediated immunity GO:0002448 20 0.052
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.052
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.051
negative regulation of inflammatory response GO:0050728 61 0.051
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.051
regulation of erk1 and erk2 cascade GO:0070372 71 0.051
urogenital system development GO:0001655 261 0.050
jnk cascade GO:0007254 72 0.050
epithelial tube morphogenesis GO:0060562 303 0.050
cytosolic calcium ion transport GO:0060401 48 0.050
cellular response to hormone stimulus GO:0032870 150 0.050
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.050
regulated secretory pathway GO:0045055 32 0.050
positive regulation of lipid metabolic process GO:0045834 40 0.049
divalent inorganic cation transport GO:0072511 178 0.049
regulation of cellular response to stress GO:0080135 159 0.049
myeloid cell activation involved in immune response GO:0002275 34 0.049
wound healing GO:0042060 157 0.049
negative regulation of type i hypersensitivity GO:0001811 1 0.049
cellular response to interleukin 4 GO:0071353 21 0.049
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 3 0.049
regulation of multi organism process GO:0043900 111 0.049
regulation of blood pressure GO:0008217 93 0.048
muscle tissue development GO:0060537 308 0.048
response to radiation GO:0009314 165 0.048
regulation of phagocytosis GO:0050764 33 0.048
cytokine mediated signaling pathway GO:0019221 115 0.047
lymphocyte proliferation GO:0046651 164 0.047
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.047
maintenance of location GO:0051235 89 0.047
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.046
nucleoside catabolic process GO:0009164 206 0.046
negative regulation of secretion GO:0051048 61 0.046
anatomical structure homeostasis GO:0060249 145 0.046
regulation of acute inflammatory response GO:0002673 27 0.046
serotonin secretion involved in inflammatory response GO:0002442 4 0.045
regulation of stress activated mapk cascade GO:0032872 69 0.045
positive regulation of b cell chemotaxis GO:2000538 2 0.045
i kappab kinase nf kappab signaling GO:0007249 85 0.045
regulation of cellular component biogenesis GO:0044087 181 0.045
regulation of fibronectin dependent thymocyte migration GO:2000413 1 0.044
regulation of eosinophil migration GO:2000416 2 0.044
single organismal cell cell adhesion GO:0016337 131 0.044
regulation of transferase activity GO:0051338 263 0.044
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.044
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.044
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.043
negative regulation of cellular component organization GO:0051129 194 0.043
response to interferon gamma GO:0034341 34 0.043
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.042
cell recognition GO:0008037 83 0.042
regulation of chemotaxis GO:0050920 53 0.042
regulation of cytokine biosynthetic process GO:0042035 59 0.042
negative regulation of mapk cascade GO:0043409 65 0.041
renal system development GO:0072001 225 0.041
cellular lipid metabolic process GO:0044255 323 0.040
positive regulation of jun kinase activity GO:0043507 30 0.040
negative regulation of hypersensitivity GO:0002884 3 0.040
response to temperature stimulus GO:0009266 55 0.040
antigen processing and presentation GO:0019882 47 0.040
cellular response to growth factor stimulus GO:0071363 197 0.039
rho protein signal transduction GO:0007266 32 0.039
epithelial cell development GO:0002064 159 0.039
regulation of lymphocyte apoptotic process GO:0070228 41 0.039
positive regulation of protein kinase activity GO:0045860 144 0.038
response to extracellular stimulus GO:0009991 127 0.038
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.038
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.038
detection of biotic stimulus GO:0009595 10 0.038
axon guidance GO:0007411 141 0.038
leukocyte mediated cytotoxicity GO:0001909 62 0.038
b cell chemotaxis GO:0035754 3 0.038
alpha beta t cell activation involved in immune response GO:0002287 31 0.037
cytokine biosynthetic process GO:0042089 68 0.037
monosaccharide transport GO:0015749 58 0.037
toxin catabolic process GO:0009407 1 0.036
calcium ion homeostasis GO:0055074 127 0.036
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.036
tissue homeostasis GO:0001894 115 0.036
histamine production involved in inflammatory response GO:0002349 1 0.035
natural killer cell chemotaxis GO:0035747 1 0.035
apoptotic signaling pathway GO:0097190 306 0.035
myeloid cell homeostasis GO:0002262 114 0.035
Mouse
regionalization GO:0003002 337 0.035
cation homeostasis GO:0055080 212 0.034
regulation of alpha beta t cell activation GO:0046634 53 0.034
neutrophil mediated immunity GO:0002446 19 0.034
positive regulation of leukocyte apoptotic process GO:2000108 21 0.034
stress activated mapk cascade GO:0051403 80 0.034
regulation of anatomical structure size GO:0090066 178 0.033
cellular response to peptide GO:1901653 92 0.033
positive regulation of mast cell activation involved in immune response GO:0033008 10 0.033
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.033
granulocyte macrophage colony stimulating factor production GO:0032604 3 0.033
regulation of cell adhesion GO:0030155 154 0.033
ras protein signal transduction GO:0007265 77 0.033
regulation of neuron apoptotic process GO:0043523 122 0.033
endocrine process GO:0050886 39 0.033
cdc42 protein signal transduction GO:0032488 0 0.032
iron ion homeostasis GO:0055072 36 0.032
regulation of lipid metabolic process GO:0019216 118 0.032
skin development GO:0043588 220 0.032
positive regulation of mapk cascade GO:0043410 170 0.032
regulation of body fluid levels GO:0050878 162 0.032
complement receptor mediated signaling pathway GO:0002430 1 0.032
connective tissue development GO:0061448 179 0.032
regulation of interleukin 6 production GO:0032675 55 0.032
response to alcohol GO:0097305 48 0.032
response to peptide hormone GO:0043434 127 0.032
positive regulation of lymphocyte proliferation GO:0050671 70 0.032
positive regulation of acute inflammatory response GO:0002675 16 0.031
extracellular matrix organization GO:0030198 147 0.031
cellular ion homeostasis GO:0006873 165 0.031
positive regulation of granulocyte chemotaxis GO:0071624 12 0.031
central nervous system neuron differentiation GO:0021953 162 0.031
myotube differentiation GO:0014902 105 0.031
purine containing compound metabolic process GO:0072521 311 0.031
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.031
positive regulation of neutrophil chemotaxis GO:0090023 12 0.030
hormone secretion GO:0046879 128 0.030
interleukin 12 secretion GO:0072610 3 0.030
response to insulin GO:0032868 100 0.030
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.030
negative regulation of molecular function GO:0044092 258 0.030
detection of molecule of bacterial origin GO:0032490 2 0.030
regulation of reactive oxygen species metabolic process GO:2000377 40 0.030
neuron death GO:0070997 154 0.030
regulation of exocytosis GO:0017157 61 0.030
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.030
kidney development GO:0001822 213 0.030
regulation of granulocyte chemotaxis GO:0071622 17 0.030
neuron migration GO:0001764 122 0.029
morphogenesis of a branching structure GO:0001763 203 0.029
epithelial cell proliferation GO:0050673 174 0.029
regulation of alpha beta t cell differentiation GO:0046637 35 0.029
negative regulation of protein phosphorylation GO:0001933 126 0.029
inositol lipid mediated signaling GO:0048017 41 0.028
carbohydrate transport GO:0008643 62 0.028
nephron development GO:0072006 109 0.028
reactive nitrogen species metabolic process GO:2001057 0 0.028
negative regulation of defense response GO:0031348 77 0.028
cd4 positive alpha beta t cell activation GO:0035710 45 0.028
positive regulation of stem cell proliferation GO:2000648 59 0.028
regulation of cellular catabolic process GO:0031329 242 0.028
regulation of membrane potential GO:0042391 192 0.028
cellular divalent inorganic cation homeostasis GO:0072503 127 0.028
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.028
membrane organization GO:0061024 245 0.028
positive regulation of apoptotic signaling pathway GO:2001235 95 0.028
transmembrane transport GO:0055085 412 0.028
positive regulation of transferase activity GO:0051347 167 0.027
mesenchymal cell differentiation GO:0048762 107 0.027
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
serotonin production involved in inflammatory response GO:0002351 4 0.027
positive regulation of type 2 immune response GO:0002830 9 0.027
positive regulation of type iii hypersensitivity GO:0001805 3 0.027
positive regulation of tumor necrosis factor production GO:0032760 30 0.027
positive regulation of jnk cascade GO:0046330 46 0.027
erk1 and erk2 cascade GO:0070371 77 0.027
protein catabolic process GO:0030163 221 0.026
negative regulation of lymphocyte proliferation GO:0050672 45 0.026
detection of peptidoglycan GO:0032499 1 0.026
regulation of t helper cell differentiation GO:0045622 14 0.026
regulation of t helper 1 cell cytokine production GO:2000554 1 0.026
positive regulation of cd4 positive alpha beta t cell differentiation GO:0043372 14 0.026
morphogenesis of a branching epithelium GO:0061138 193 0.026
positive regulation of type ii hypersensitivity GO:0002894 4 0.026
fatty acid metabolic process GO:0006631 121 0.026
positive regulation of cellular component biogenesis GO:0044089 94 0.026
response to growth factor GO:0070848 198 0.026
macromolecule catabolic process GO:0009057 281 0.026
cytokine production involved in immune response GO:0002367 34 0.026
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.026
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.026
negative regulation of growth GO:0045926 99 0.025
positive regulation of angiogenesis GO:0045766 46 0.025
defense response to gram positive bacterium GO:0050830 50 0.025
interleukin 1 beta production GO:0032611 30 0.025
nucleoside metabolic process GO:0009116 246 0.025
striated muscle tissue development GO:0014706 293 0.025
protein activation cascade GO:0072376 19 0.025
regulation of t cell mediated immunity GO:0002709 34 0.025
negative regulation of intracellular signal transduction GO:1902532 167 0.025
oxidation reduction process GO:0055114 342 0.025
positive regulation of regulated secretory pathway GO:1903307 10 0.025
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.025
renal system process GO:0003014 48 0.024
tissue remodeling GO:0048771 102 0.024
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.024
dna biosynthetic process GO:0071897 22 0.024
positive regulation of camp mediated signaling GO:0043950 3 0.024
stem cell differentiation GO:0048863 268 0.024
response to oxygen levels GO:0070482 62 0.024
mature dendritic cell differentiation GO:0097029 3 0.024
mesenchymal cell development GO:0014031 93 0.024
cell fate commitment GO:0045165 210 0.024
regulation of interferon gamma production GO:0032649 57 0.024
neuron apoptotic process GO:0051402 142 0.024
syncytium formation by plasma membrane fusion GO:0000768 42 0.023
lysosome localization GO:0032418 20 0.023
mature natural killer cell chemotaxis GO:0035782 1 0.023
lipid localization GO:0010876 126 0.023
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.023
gliogenesis GO:0042063 141 0.023
protein ubiquitination GO:0016567 171 0.023
regulation of tumor necrosis factor production GO:0032680 49 0.023
antigen receptor mediated signaling pathway GO:0050851 64 0.023
neuron projection guidance GO:0097485 141 0.023
nitrogen compound transport GO:0071705 271 0.023
aromatic compound catabolic process GO:0019439 286 0.023
positive regulation of intracellular transport GO:0032388 70 0.023
positive regulation of exocytosis GO:0045921 20 0.023
skeletal system morphogenesis GO:0048705 203 0.023
vascular process in circulatory system GO:0003018 62 0.023
regulation of t helper 2 cell cytokine production GO:2000551 3 0.023
serotonin secretion GO:0001820 8 0.023
receptor mediated endocytosis GO:0006898 51 0.023
regulation of rho protein signal transduction GO:0035023 71 0.023
hexose transport GO:0008645 56 0.023
detection of lipoteichoic acid GO:0070392 1 0.023
ear development GO:0043583 200 0.022
negative regulation of t helper 1 cell differentiation GO:0045626 3 0.022
positive regulation of calcium ion transport GO:0051928 27 0.022
stress activated protein kinase signaling cascade GO:0031098 81 0.022
cellular carbohydrate metabolic process GO:0044262 119 0.022
olfactory learning GO:0008355 2 0.022
organic hydroxy compound transport GO:0015850 93 0.022

Slc11a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
respiratory system disease DOID:1579 0 0.030
disease of anatomical entity DOID:7 0 0.030