|
|
synaptic transmission
|
GO:0007268 |
329 |
0.991
|
|
|
|
synaptic transmission glutamatergic
|
GO:0035249 |
36 |
0.935
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.903
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.900
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.891
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.875
|
Mouse |
|
|
learning
|
GO:0007612 |
98 |
0.870
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.835
|
Mouse Worm |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.833
|
Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.830
|
Mouse Fly |
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.824
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.779
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.768
|
Mouse |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.731
|
Mouse |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.723
|
Mouse |
|
|
positive regulation of heart rate by epinephrine norepinephrine
|
GO:0001996 |
4 |
0.696
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.689
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.684
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.681
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.667
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.665
|
|
|
|
memory
|
GO:0007613 |
58 |
0.665
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.657
|
Mouse |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.655
|
|
|
|
conditioned taste aversion
|
GO:0001661 |
4 |
0.652
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.651
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.651
|
Mouse |
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.646
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.635
|
Mouse Worm |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.627
|
|
|
|
regulation of high voltage gated calcium channel activity
|
GO:1901841 |
2 |
0.621
|
|
|
|
positive regulation of fat cell proliferation
|
GO:0070346 |
1 |
0.621
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.619
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.607
|
Mouse Worm |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.607
|
Mouse |
|
|
cell cell signaling involved in lung development
|
GO:0060495 |
1 |
0.607
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.606
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.597
|
|
|
|
response to amphetamine
|
GO:0001975 |
16 |
0.594
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.590
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.586
|
Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.584
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.584
|
|
|
|
positive regulation of the force of heart contraction by chemical signal
|
GO:0003099 |
3 |
0.583
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.583
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.579
|
|
|
|
histamine induced gastric acid secretion
|
GO:0001697 |
1 |
0.579
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.574
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.573
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.571
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.571
|
|
|
|
regulation of white fat cell proliferation
|
GO:0070350 |
2 |
0.563
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.560
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.545
|
|
|
|
positive regulation of the force of heart contraction by epinephrine norepinephrine
|
GO:0001997 |
3 |
0.539
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.538
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.535
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.535
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.528
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.526
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.522
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.520
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.514
|
|
|
|
hippocampus development
|
GO:0021766 |
52 |
0.514
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.513
|
|
|
|
bronchiole morphogenesis
|
GO:0060436 |
1 |
0.510
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.510
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.507
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.505
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.503
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.500
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.497
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.491
|
|
|
|
positive regulation of voltage gated calcium channel activity
|
GO:1901387 |
2 |
0.490
|
|
|
|
operant conditioning
|
GO:0035106 |
2 |
0.488
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.488
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.486
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.485
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.485
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
30 |
0.484
|
|
|
|
positive regulation of high voltage gated calcium channel activity
|
GO:1901843 |
1 |
0.484
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.482
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.482
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.478
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.474
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.469
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.468
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.465
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.464
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.459
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.456
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.453
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.453
|
|
|
|
camp mediated signaling
|
GO:0019933 |
15 |
0.451
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.450
|
|
|
|
sensitization
|
GO:0046960 |
2 |
0.449
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.448
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.447
|
|
|
|
semicircular canal fusion
|
GO:0060879 |
1 |
0.439
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.438
|
Mouse Worm |
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.437
|
|
|
|
serotonin metabolic process
|
GO:0042428 |
8 |
0.436
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.435
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.435
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.434
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.434
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.425
|
|
|
|
white fat cell proliferation
|
GO:0070343 |
2 |
0.423
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.423
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.418
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.417
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.416
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.415
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.408
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.406
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.403
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.397
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.391
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.391
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.390
|
Fly |
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
25 |
0.390
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.389
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.388
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.386
|
|
|
|
thyroid stimulating hormone secreting cell differentiation
|
GO:0060129 |
4 |
0.385
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.384
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.384
|
Worm |
|
|
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure
|
GO:0002025 |
3 |
0.384
|
|
|
|
regulation of systemic arterial blood pressure by norepinephrine epinephrine
|
GO:0001993 |
8 |
0.382
|
|
|
|
fear response
|
GO:0042596 |
33 |
0.381
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.381
|
|
|
|
visual behavior
|
GO:0007632 |
45 |
0.377
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.376
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.370
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.364
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.362
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.357
|
|
|
|
phospholipase c activating serotonin receptor signaling pathway
|
GO:0007208 |
1 |
0.352
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.352
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.349
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.348
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.347
|
Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.345
|
Mouse |
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.344
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.344
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.339
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.334
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.329
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.327
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.326
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.326
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
143 |
0.323
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.322
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.321
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.321
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.319
|
|
|
|
cellular response to temperature stimulus
|
GO:0071502 |
2 |
0.317
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.317
|
|
|
|
regulation of serotonin secretion
|
GO:0014062 |
3 |
0.315
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.310
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.308
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.308
|
|
|
|
regulation of synaptic transmission glutamatergic
|
GO:0051966 |
19 |
0.305
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.305
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
31 |
0.303
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
19 |
0.301
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.298
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.295
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.295
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.293
|
Fly |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.292
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.285
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.285
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.284
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.281
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.280
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.280
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.280
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.280
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.280
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.275
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.275
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.275
|
|
|
|
lung proximal distal axis specification
|
GO:0061115 |
1 |
0.272
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.269
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.268
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.267
|
|
|
|
mesenchymal epithelial cell signaling involved in lung development
|
GO:0060496 |
1 |
0.266
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.262
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.260
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.260
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.260
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.259
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.258
|
|
|
|
catecholamine metabolic process
|
GO:0006584 |
30 |
0.257
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.256
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.256
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.255
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.253
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.252
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.250
|
|
|
|
gastrin induced gastric acid secretion
|
GO:0001698 |
1 |
0.249
|
|
|
|
positive regulation of glycolytic process
|
GO:0045821 |
4 |
0.249
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.249
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.248
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.247
|
|
|
|
habituation
|
GO:0046959 |
3 |
0.247
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.245
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.244
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.238
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.237
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.235
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.235
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.232
|
|
|
|
male anatomical structure morphogenesis
|
GO:0090598 |
4 |
0.231
|
|
|
|
establishment of neuroblast polarity
|
GO:0045200 |
1 |
0.230
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.228
|
|
|
|
primary amino compound metabolic process
|
GO:1901160 |
8 |
0.227
|
|
|
|
tor signaling
|
GO:0031929 |
21 |
0.227
|
Fly |
|
|
sensory perception
|
GO:0007600 |
245 |
0.225
|
|
|
|
somatotropin secreting cell differentiation
|
GO:0060126 |
4 |
0.222
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.222
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.222
|
Mouse |
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.219
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.219
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.217
|
Worm |
|
|
membrane organization
|
GO:0061024 |
245 |
0.217
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.216
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.212
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.212
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.211
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.210
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.209
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.206
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.206
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.203
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.202
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.202
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.201
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.199
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.199
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.198
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.198
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.198
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.198
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.197
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.196
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
38 |
0.196
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.195
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.195
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.194
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.194
|
|
|
|
behavioral defense response
|
GO:0002209 |
28 |
0.191
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.190
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.189
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.189
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.188
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.186
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.186
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.186
|
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
8 |
0.185
|
|
|
|
cyclic nucleotide mediated signaling
|
GO:0019935 |
18 |
0.184
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.183
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.183
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.182
|
|
|
|
positive regulation of white fat cell proliferation
|
GO:0070352 |
1 |
0.182
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.182
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.182
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.181
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.180
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.178
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.177
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.177
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.175
|
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.175
|
|
|
|
phospholipase c activating dopamine receptor signaling pathway
|
GO:0060158 |
5 |
0.175
|
|
|
|
embryonic genitalia morphogenesis
|
GO:0030538 |
4 |
0.174
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.174
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.174
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.173
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.173
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.173
|
|
|
|
female genitalia morphogenesis
|
GO:0048807 |
3 |
0.173
|
|
|
|
negative regulation of purine nucleotide metabolic process
|
GO:1900543 |
16 |
0.171
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.171
|
|
|
|
fat cell proliferation
|
GO:0070341 |
4 |
0.171
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.170
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.169
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.168
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
15 |
0.167
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.167
|
|
|
|
behavioral response to cocaine
|
GO:0048148 |
10 |
0.166
|
|
|
|
adrenergic receptor signaling pathway
|
GO:0071875 |
13 |
0.165
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.164
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.164
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.163
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.163
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.163
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.162
|
Mouse Fly |
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.161
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.161
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.160
|
|
|
|
positive regulation of blood pressure by epinephrine norepinephrine
|
GO:0003321 |
6 |
0.160
|
|
|
|
harderian gland development
|
GO:0070384 |
2 |
0.159
|
|
|
|
regulation of the force of heart contraction
|
GO:0002026 |
17 |
0.159
|
|
|
|
detection of light stimulus
|
GO:0009583 |
25 |
0.159
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.158
|
|
|
|
regulation of cation channel activity
|
GO:2001257 |
22 |
0.158
|
|
|
|
submandibular salivary gland formation
|
GO:0060661 |
1 |
0.158
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.157
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.156
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.156
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.155
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.155
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.154
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.153
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.152
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.151
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
22 |
0.151
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.150
|
|
|
|
indole containing compound metabolic process
|
GO:0042430 |
12 |
0.149
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.146
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.145
|
|
|
|
monoamine transport
|
GO:0015844 |
33 |
0.144
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
24 |
0.144
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.144
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.143
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.143
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.143
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
27 |
0.143
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.142
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.142
|
|
|
|
regulation of camp mediated signaling
|
GO:0043949 |
7 |
0.142
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.142
|
|
|
|
response to amine
|
GO:0014075 |
16 |
0.141
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.141
|
|
|
|
response to ammonium ion
|
GO:0060359 |
21 |
0.140
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.138
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.138
|
Mouse |
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.138
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.136
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.136
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.135
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.134
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.134
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.133
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.133
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.132
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.132
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.131
|
|
|
|
mammary gland bud formation
|
GO:0060615 |
2 |
0.130
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
26 |
0.129
|
|
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.128
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.127
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.127
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.127
|
|
|
|
white fat cell differentiation
|
GO:0050872 |
15 |
0.126
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.126
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.126
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.125
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.124
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.124
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.122
|
|
|
|
negative regulation of nucleotide metabolic process
|
GO:0045980 |
16 |
0.122
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.121
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.121
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.121
|
|
|
|
positive regulation of cellular carbohydrate metabolic process
|
GO:0010676 |
29 |
0.119
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.119
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.119
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
17 |
0.118
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.118
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.117
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.117
|
|
|
|
dopamine receptor signaling pathway
|
GO:0007212 |
16 |
0.116
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.116
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.115
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.115
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.115
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.114
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.114
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.114
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.113
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.113
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.112
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.112
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.112
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.111
|
|
|
|
regulation of protein complex disassembly
|
GO:0043244 |
28 |
0.111
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.111
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
19 |
0.111
|
|
|
|
positive regulation of synaptic transmission glutamatergic
|
GO:0051968 |
8 |
0.110
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.110
|
|
|
|
midgut development
|
GO:0007494 |
4 |
0.110
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.110
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.109
|
Mouse |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.109
|
|
|
|
reflex
|
GO:0060004 |
22 |
0.108
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.108
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.107
|
|
|
|
protein complex disassembly
|
GO:0043241 |
40 |
0.106
|
|
|
|
gamma aminobutyric acid signaling pathway
|
GO:0007214 |
8 |
0.106
|
|
|
|
pigment metabolic process
|
GO:0042440 |
32 |
0.105
|
Fly |
|
|
limbic system development
|
GO:0021761 |
72 |
0.104
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.104
|
|
|
|
regulation of fat cell proliferation
|
GO:0070344 |
4 |
0.103
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.103
|
|
|
|
substrate independent telencephalic tangential migration
|
GO:0021826 |
8 |
0.103
|
|
|
|
regulation of extent of cell growth
|
GO:0061387 |
52 |
0.102
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.102
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.101
|
|
|
|
fast calcium ion dependent exocytosis of neurotransmitter
|
GO:0098746 |
1 |
0.101
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
13 |
0.100
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.100
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.100
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.100
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.100
|
|
|
|
response to cocaine
|
GO:0042220 |
14 |
0.100
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.100
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.099
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.099
|
|
|
|
somatotropin secreting cell development
|
GO:0060133 |
2 |
0.099
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.099
|
|
|
|
cerebral cortex neuron differentiation
|
GO:0021895 |
19 |
0.098
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.097
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.096
|
|
|
|
semicircular canal formation
|
GO:0060876 |
1 |
0.096
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.095
|
|
|
|
mesenchymal cell differentiation involved in lung development
|
GO:0060915 |
2 |
0.095
|
|
|
|
regulation of g protein activated inward rectifier potassium channel activity
|
GO:1900128 |
1 |
0.095
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.095
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.095
|
|
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
58 |
0.094
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.094
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.092
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.092
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.092
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.092
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.091
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.091
|
|
|
|
positive regulation of vascular endothelial growth factor receptor signaling pathway
|
GO:0030949 |
5 |
0.091
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
21 |
0.091
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.090
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.088
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.088
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.088
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.088
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.088
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.088
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.087
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.087
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.087
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.086
|
|
|
|
cell proliferation in hindbrain
|
GO:0021534 |
10 |
0.086
|
|
|
|
secondary metabolic process
|
GO:0019748 |
18 |
0.086
|
Fly |
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.086
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.085
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.085
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.085
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.085
|
|
|
|
long term synaptic depression
|
GO:0060292 |
13 |
0.085
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.085
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.084
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.084
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.083
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
43 |
0.083
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.083
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.083
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.083
|
|
|
|
protein kinase a signaling
|
GO:0010737 |
7 |
0.083
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.083
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.083
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.082
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.081
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.081
|
|
|
|
corticotropin hormone secreting cell differentiation
|
GO:0060128 |
3 |
0.081
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.081
|
|
|
|
establishment or maintenance of neuroblast polarity
|
GO:0045196 |
1 |
0.080
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.080
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.079
|
|
|
|
branch elongation involved in salivary gland morphogenesis
|
GO:0060667 |
2 |
0.079
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.078
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.078
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.078
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.078
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
3 |
0.077
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.076
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.076
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.076
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.076
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.076
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
12 |
0.076
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.076
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.076
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.076
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.075
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.075
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.075
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.075
|
Worm |
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.075
|
|
