Mus musculus

62 known processes

Dio3

deiodinase, iodothyronine type III

(Aliases: MGC124117,MGC124118)

Dio3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of female receptivity GO:0045924 6 0.088
positive regulation of cellular amine metabolic process GO:0033240 5 0.073
camera type eye development GO:0043010 266 0.068
placenta development GO:0001890 140 0.067
cellular amino acid metabolic process GO:0006520 103 0.066
carbon catabolite activation of transcription GO:0045991 4 0.065
female mating behavior GO:0060180 8 0.065
retinal cone cell development GO:0046549 8 0.058
embryonic placenta development GO:0001892 98 0.054
spermatogenesis GO:0007283 284 0.053
epithelial tube morphogenesis GO:0060562 303 0.050
striated muscle tissue development GO:0014706 293 0.050
male gamete generation GO:0048232 285 0.049
regulation of response to drug GO:2001023 2 0.048
carbon catabolite regulation of transcription GO:0045990 4 0.047
sensory perception of umami taste GO:0050917 4 0.047
gland development GO:0048732 330 0.046
regulation of phospholipase c activity GO:1900274 3 0.046
sensory perception of mechanical stimulus GO:0050954 107 0.043
morphogenesis of a branching epithelium GO:0061138 193 0.043
cholesterol homeostasis GO:0042632 44 0.043
sensory perception GO:0007600 245 0.043
labyrinthine layer development GO:0060711 49 0.042
positive regulation of cell death GO:0010942 224 0.042
regulation of membrane potential GO:0042391 192 0.041
protein catabolic process GO:0030163 221 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
regulation of muscle tissue development GO:1901861 97 0.039
negative regulation of female receptivity GO:0007621 2 0.038
inflammatory response GO:0006954 244 0.036
nitrogen compound transport GO:0071705 271 0.036
lipid homeostasis GO:0055088 63 0.036
muscle cell differentiation GO:0042692 261 0.035
male sex differentiation GO:0046661 109 0.035
regulation of feeding behavior GO:0060259 3 0.034
forebrain development GO:0030900 302 0.033
cellular ketone metabolic process GO:0042180 84 0.033
macromolecule catabolic process GO:0009057 281 0.033
positive regulation of apoptotic process GO:0043065 217 0.033
transmission of nerve impulse GO:0019226 76 0.033
posttranscriptional regulation of gene expression GO:0010608 155 0.033
heart process GO:0003015 94 0.032
action potential GO:0001508 78 0.032
response to lipopolysaccharide GO:0032496 128 0.032
neural tube formation GO:0001841 108 0.031
acetylcholine transport GO:0015870 2 0.031
blood circulation GO:0008015 195 0.031
positive regulation of programmed cell death GO:0043068 218 0.031
cellular response to lipopolysaccharide GO:0071222 77 0.031
regulation of homeostatic process GO:0032844 182 0.031
cellular response to molecule of bacterial origin GO:0071219 83 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.030
lung development GO:0030324 164 0.030
cellular response to monosaccharide stimulus GO:0071326 47 0.029
skeletal muscle organ development GO:0060538 163 0.029
fertilization GO:0009566 127 0.029
response to acid chemical GO:0001101 111 0.028
mesonephric epithelium development GO:0072163 94 0.028
cellular response to biotic stimulus GO:0071216 92 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
limb development GO:0060173 166 0.028
proteasomal protein catabolic process GO:0010498 98 0.028
telencephalon development GO:0021537 186 0.028
cardiac muscle tissue development GO:0048738 130 0.028
cytoplasmic transport GO:0016482 234 0.028
cellular macromolecule catabolic process GO:0044265 206 0.027
translation GO:0006412 93 0.027
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.027
negative regulation of translational initiation GO:0045947 4 0.027
cellular modified amino acid metabolic process GO:0006575 63 0.027
carbohydrate homeostasis GO:0033500 128 0.027
type i pneumocyte differentiation GO:0060509 7 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
carbohydrate metabolic process GO:0005975 230 0.027
cellular chemical homeostasis GO:0055082 215 0.026
skeletal system development GO:0001501 356 0.026
respiratory tube development GO:0030323 167 0.026
positive regulation of nervous system development GO:0051962 221 0.026
morphogenesis of a branching structure GO:0001763 203 0.026
cellular carbohydrate metabolic process GO:0044262 119 0.026
regulation of glucose metabolic process GO:0010906 60 0.025
female courtship behavior GO:0008050 3 0.025
neural tube development GO:0021915 160 0.025
oxidation reduction process GO:0055114 342 0.025
cognition GO:0050890 149 0.025
homeostasis of number of cells GO:0048872 210 0.025
male gonad development GO:0008584 88 0.024
appendage morphogenesis GO:0035107 149 0.024
epithelial cell development GO:0002064 159 0.024
appendage development GO:0048736 166 0.024
multicellular organismal signaling GO:0035637 91 0.024
mesonephros development GO:0001823 97 0.024
cellular response to acid chemical GO:0071229 68 0.024
granulocyte differentiation GO:0030851 17 0.024
peptidyl amino acid modification GO:0018193 336 0.024
tube formation GO:0035148 140 0.024
organic hydroxy compound metabolic process GO:1901615 203 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
embryonic limb morphogenesis GO:0030326 126 0.024
ear development GO:0043583 200 0.024
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.024
acetate ester transport GO:1901374 2 0.023
cardiac septum development GO:0003279 59 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
development of primary male sexual characteristics GO:0046546 88 0.023
generation of precursor metabolites and energy GO:0006091 103 0.023
multicellular organism growth GO:0035264 161 0.023
carboxylic acid biosynthetic process GO:0046394 86 0.022
regulation of translation GO:0006417 71 0.022
myeloid cell homeostasis GO:0002262 114 0.022
regionalization GO:0003002 337 0.022
monosaccharide metabolic process GO:0005996 106 0.022
t cell activation GO:0042110 289 0.022
regulation of receptor activity GO:0010469 41 0.022
embryonic organ morphogenesis GO:0048562 276 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
intracellular receptor signaling pathway GO:0030522 74 0.021
regulation of hormone levels GO:0010817 211 0.021
circulatory system process GO:0003013 197 0.021
regulation of blood circulation GO:1903522 93 0.021
developmental cell growth GO:0048588 84 0.021
developmental growth involved in morphogenesis GO:0060560 138 0.021
regulation of ossification GO:0030278 112 0.021
regulation of cholesterol metabolic process GO:0090181 14 0.021
negative regulation of translation GO:0017148 22 0.021
cellular amine metabolic process GO:0044106 44 0.020
limb morphogenesis GO:0035108 149 0.020
embryonic appendage morphogenesis GO:0035113 126 0.020
sensory perception of sound GO:0007605 97 0.020
ossification GO:0001503 216 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
cellular protein catabolic process GO:0044257 155 0.020
hematopoietic progenitor cell differentiation GO:0002244 143 0.020
regulation of response to wounding GO:1903034 189 0.020
embryonic placenta morphogenesis GO:0060669 25 0.020
liver development GO:0001889 66 0.020
cellular homeostasis GO:0019725 240 0.020
cardiac muscle cell differentiation GO:0055007 69 0.020
cation transport GO:0006812 399 0.020
heart contraction GO:0060047 93 0.020
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.019
endocrine system development GO:0035270 98 0.019
regulation of intracellular transport GO:0032386 159 0.019
organic acid biosynthetic process GO:0016053 86 0.019
morphogenesis of embryonic epithelium GO:0016331 159 0.019
neural tube closure GO:0001843 90 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.019
labyrinthine layer morphogenesis GO:0060713 21 0.019
chromatin organization GO:0006325 206 0.019
response to drug GO:0042493 75 0.019
energy homeostasis GO:0097009 15 0.018
maintenance of location GO:0051235 89 0.018
cellular response to hexose stimulus GO:0071331 47 0.018
positive regulation of cell development GO:0010720 237 0.018
response to molecule of bacterial origin GO:0002237 143 0.018
histone modification GO:0016570 159 0.018
sterol homeostasis GO:0055092 45 0.018
cell growth GO:0016049 130 0.018
mapk cascade GO:0000165 281 0.018
cellular response to carbohydrate stimulus GO:0071322 50 0.018
muscle tissue development GO:0060537 308 0.017
response to organonitrogen compound GO:0010243 246 0.017
regulation of inflammatory response GO:0050727 147 0.017
eye photoreceptor cell development GO:0042462 31 0.017
neural precursor cell proliferation GO:0061351 121 0.017
skeletal system morphogenesis GO:0048705 203 0.017
regulation of carbohydrate metabolic process GO:0006109 75 0.017
regulation of myotube differentiation GO:0010830 62 0.017
ureteric bud development GO:0001657 94 0.017
wound healing GO:0042060 157 0.017
cardiocyte differentiation GO:0035051 87 0.017
mammary gland duct morphogenesis GO:0060603 38 0.016
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.016
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.016
regulation of transferase activity GO:0051338 263 0.016
regulation of cell projection organization GO:0031344 206 0.016
lung epithelium development GO:0060428 37 0.016
rhythmic process GO:0048511 174 0.016
methylation GO:0032259 134 0.016
cellular glucose homeostasis GO:0001678 52 0.016
endochondral bone morphogenesis GO:0060350 50 0.016
embryonic epithelial tube formation GO:0001838 130 0.016
glandular epithelial cell differentiation GO:0002067 38 0.016
cellular response to glucose stimulus GO:0071333 45 0.016
primary neural tube formation GO:0014020 95 0.016
central nervous system neuron differentiation GO:0021953 162 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
monocarboxylic acid biosynthetic process GO:0072330 61 0.016
heart morphogenesis GO:0003007 178 0.016
mammary gland morphogenesis GO:0060443 54 0.015
kidney development GO:0001822 213 0.015
sensory organ morphogenesis GO:0090596 242 0.015
single organism cell adhesion GO:0098602 156 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
response to extracellular stimulus GO:0009991 127 0.015
negative regulation of protein localization to nucleus GO:1900181 23 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
glucose homeostasis GO:0042593 128 0.015
chromatin modification GO:0016568 187 0.015
epithelial cell proliferation GO:0050673 174 0.015
regulation of heart contraction GO:0008016 77 0.015
renal system development GO:0072001 225 0.015
positive regulation of phospholipase c activity GO:0010863 2 0.015
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.015
protein localization to organelle GO:0033365 185 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
amide transport GO:0042886 138 0.015
regulation of protein localization GO:0032880 231 0.015
hexose metabolic process GO:0019318 98 0.015
response to monosaccharide GO:0034284 67 0.015
erythrocyte differentiation GO:0030218 88 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
thyroid hormone mediated signaling pathway GO:0002154 3 0.015
nuclear division GO:0000280 158 0.015
positive regulation of phospholipase activity GO:0010518 3 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
hepaticobiliary system development GO:0061008 67 0.015
organ growth GO:0035265 117 0.014
hormone secretion GO:0046879 128 0.014
response to leptin GO:0044321 7 0.014
regulation of osteoblast differentiation GO:0045667 67 0.014
cardiac septum morphogenesis GO:0060411 46 0.014
multi multicellular organism process GO:0044706 109 0.014
chondrocyte differentiation GO:0002062 72 0.014
metal ion homeostasis GO:0055065 189 0.014
small molecule biosynthetic process GO:0044283 132 0.014
cellular response to extracellular stimulus GO:0031668 81 0.014
cellular response to drug GO:0035690 15 0.014
bone development GO:0060348 120 0.014
positive regulation of myotube differentiation GO:0010831 24 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
respiratory system development GO:0060541 190 0.014
regulation of striated muscle cell differentiation GO:0051153 81 0.014
ion transmembrane transport GO:0034220 361 0.014
cartilage development GO:0051216 140 0.013
protein dna complex subunit organization GO:0071824 28 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
steroid metabolic process GO:0008202 119 0.013
regulation of protein import into nucleus GO:0042306 52 0.013
urogenital system development GO:0001655 261 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
cell type specific apoptotic process GO:0097285 268 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
tube closure GO:0060606 91 0.013
adult locomotory behavior GO:0008344 91 0.013
response to retinoic acid GO:0032526 56 0.013
regulation of protein complex assembly GO:0043254 83 0.013
transmembrane transport GO:0055085 412 0.013
amine metabolic process GO:0009308 45 0.013
development of primary sexual characteristics GO:0045137 143 0.013
cholesterol metabolic process GO:0008203 56 0.013
glucose metabolic process GO:0006006 92 0.013
energy derivation by oxidation of organic compounds GO:0015980 77 0.012
positive regulation of receptor activity GO:2000273 17 0.012
protein targeting GO:0006605 143 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
protein ubiquitination GO:0016567 171 0.012
intracellular protein transport GO:0006886 204 0.012
positive regulation of ossification GO:0045778 47 0.012
retinal cone cell differentiation GO:0042670 8 0.012
photoreceptor cell differentiation GO:0046530 52 0.012
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
peptide secretion GO:0002790 114 0.012
spermatid development GO:0007286 108 0.012
cation transmembrane transport GO:0098655 266 0.012
regulation of mapk cascade GO:0043408 248 0.012
organelle fission GO:0048285 170 0.012
type b pancreatic cell proliferation GO:0044342 10 0.012
cytoplasmic sequestering of transcription factor GO:0042994 5 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
cellular hyperosmotic salinity response GO:0071475 0 0.012
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.012
cation homeostasis GO:0055080 212 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
blood coagulation GO:0007596 76 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.011
regulation of secretion GO:0051046 274 0.011
cardiac chamber development GO:0003205 108 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.011
prostate gland development GO:0030850 48 0.011
adult behavior GO:0030534 135 0.011
protein import GO:0017038 101 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
stem cell differentiation GO:0048863 268 0.011
cardiac chamber morphogenesis GO:0003206 93 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
embryonic camera type eye development GO:0031076 36 0.011
epithelial tube formation GO:0072175 130 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
digestive tract development GO:0048565 190 0.011
regulation of cell activation GO:0050865 289 0.011
digestive system development GO:0055123 200 0.011
response to nutrient levels GO:0031667 109 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
subpallium development GO:0021544 20 0.011
dna modification GO:0006304 50 0.011
chondrocyte hypertrophy GO:0003415 4 0.011
positive regulation of muscle cell differentiation GO:0051149 39 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
regulation of thyroid hormone mediated signaling pathway GO:0002155 3 0.011
bone morphogenesis GO:0060349 78 0.011
regulation of kinase activity GO:0043549 249 0.011
regulation of protein transport GO:0051223 163 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
regulation of translational initiation GO:0006446 15 0.011
regulation of organelle organization GO:0033043 289 0.011
response to temperature stimulus GO:0009266 55 0.011
regulation of body fluid levels GO:0050878 162 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
dephosphorylation GO:0016311 129 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.011
protein acylation GO:0043543 64 0.010
fat cell differentiation GO:0045444 160 0.010
response to vitamin d GO:0033280 3 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
nuclear import GO:0051170 95 0.010
angiogenesis GO:0001525 201 0.010
microtubule based process GO:0007017 236 0.010
calcium ion transport GO:0006816 159 0.010
neuronal action potential GO:0019228 54 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
histone acetylation GO:0016573 41 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
regulation of defense response GO:0031347 233 0.010
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
circadian rhythm GO:0007623 114 0.010
muscle system process GO:0003012 141 0.010
nuclear transport GO:0051169 139 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
bone mineralization GO:0030282 54 0.010
germ cell development GO:0007281 185 0.010
protein maturation GO:0051604 176 0.010
cell maturation GO:0048469 127 0.010

Dio3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
endocrine system disease DOID:28 0 0.021
thyroid gland disease DOID:50 0 0.014
hypothyroidism DOID:1459 0 0.014