|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.567
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.355
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.350
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.331
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.239
|
Human Mouse |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.214
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.213
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.206
|
Human Mouse |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.197
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.195
|
Rat |
|
|
blood circulation
|
GO:0008015 |
195 |
0.194
|
Mouse |
|
|
regulation of system process
|
GO:0044057 |
200 |
0.192
|
Mouse Rat |
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.182
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.181
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.177
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.173
|
Human Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.173
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.164
|
Human Zebrafish Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.161
|
Human Mouse |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.158
|
|
|
|
neutrophil activation involved in immune response
|
GO:0002283 |
8 |
0.156
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.150
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.139
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.132
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.129
|
Human Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.128
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.127
|
Human Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.127
|
Human Mouse |
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.126
|
Human Mouse |
|
|
membrane organization
|
GO:0061024 |
245 |
0.126
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.124
|
Rat |
|
|
wound healing
|
GO:0042060 |
157 |
0.124
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.123
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.123
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.121
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.119
|
Mouse |
|
|
muscle contraction
|
GO:0006936 |
101 |
0.119
|
Rat |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.115
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.113
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.111
|
Human Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.110
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.109
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.104
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.101
|
Human Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.100
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.099
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.095
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.095
|
Human Mouse |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.095
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.095
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.093
|
Rat |
|
|
cytokine production
|
GO:0001816 |
319 |
0.092
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.090
|
Human Mouse |
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.089
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.088
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.088
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.088
|
Human |
|
|
angiogenesis
|
GO:0001525 |
201 |
0.086
|
Human Zebrafish Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.086
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.086
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.084
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
26 |
0.084
|
Human Mouse |
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.082
|
|
|
|
tube closure
|
GO:0060606 |
91 |
0.081
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.080
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.079
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.079
|
Human Mouse |
|
|
coagulation
|
GO:0050817 |
78 |
0.079
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.078
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.077
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.077
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.076
|
Human Mouse |
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.076
|
Human Mouse |
|
|
placenta development
|
GO:0001890 |
140 |
0.075
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.075
|
Human Mouse |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.075
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.075
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.075
|
Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.074
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.073
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.072
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.072
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.071
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.071
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.071
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
139 |
0.070
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.070
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.069
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.069
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.068
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.068
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.066
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.066
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.065
|
Mouse |
|
|
organelle localization
|
GO:0051640 |
179 |
0.064
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.063
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.063
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.063
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.062
|
Human Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.062
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.061
|
Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.061
|
|
|
|
serotonin secretion involved in inflammatory response
|
GO:0002442 |
4 |
0.060
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.060
|
|
|
|
serotonin production involved in inflammatory response
|
GO:0002351 |
4 |
0.060
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.060
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.059
|
Human Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.059
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.059
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.059
|
Mouse |
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.059
|
Human Mouse |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.057
|
|
|
|
receptor internalization
|
GO:0031623 |
16 |
0.057
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.057
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.057
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.056
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.056
|
Human Mouse |
|
|
neural tube formation
|
GO:0001841 |
108 |
0.055
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.055
|
Mouse |
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.055
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.055
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.055
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.054
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.054
|
Mouse |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.052
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.052
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.052
|
Human Mouse |
|
|
ossification
|
GO:0001503 |
216 |
0.052
|
Mouse |
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.052
|
Human Mouse |
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.052
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.052
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.051
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.050
|
Mouse |
|
|
neuron death
|
GO:0070997 |
154 |
0.050
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.050
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.050
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.049
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.049
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
28 |
0.049
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.049
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.049
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.048
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.048
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.048
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.047
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.047
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.047
|
|
|
|
fc epsilon receptor signaling pathway
|
GO:0038095 |
3 |
0.046
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.046
|
Human Mouse |
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.046
|
Human |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.046
|
Mouse |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.046
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.046
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.046
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.046
|
Human Mouse |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.045
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.045
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.045
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.045
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.045
|
Human Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.045
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
31 |
0.044
|
Human Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.044
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.044
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.044
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.044
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.044
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.044
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.044
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.044
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.043
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.043
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.043
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.043
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.043
|
Human Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.043
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.043
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.043
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.043
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.043
|
|
|
|
negative regulation of g protein coupled receptor protein signaling pathway
|
GO:0045744 |
12 |
0.043
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.042
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.042
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.042
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.042
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.042
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.041
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.041
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.041
|
Mouse |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.041
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.040
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.040
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.040
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.040
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.040
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.040
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.040
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.040
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.039
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.039
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.039
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.039
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.039
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.039
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.039
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.039
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.039
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.039
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway
|
GO:0002029 |
5 |
0.039
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.039
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.039
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.039
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.038
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.038
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.038
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.038
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.038
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.038
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.038
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.038
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
93 |
0.038
|
Mouse |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.038
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.037
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.037
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.037
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.037
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.037
|
|
|
|
fc receptor mediated stimulatory signaling pathway
|
GO:0002431 |
4 |
0.037
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.037
|
Mouse |
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.036
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.036
|
Human Mouse |
|
|
protein processing
|
GO:0016485 |
163 |
0.036
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.036
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.036
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.036
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.036
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.035
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.035
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.035
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.035
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.035
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.035
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.035
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.034
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.034
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.034
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.034
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.034
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.034
|
|
|
|
positive regulation of myeloid leukocyte cytokine production involved in immune response
|
GO:0061081 |
9 |
0.034
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.033
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.033
|
Mouse |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.033
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
19 |
0.033
|
Human Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.033
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
25 |
0.033
|
Human Mouse |
|
|
trunk neural crest cell migration
|
GO:0036484 |
4 |
0.033
|
|
|
|
vasoconstriction
|
GO:0042310 |
27 |
0.033
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.033
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.033
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.033
|
Rat |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.033
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.033
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.033
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.033
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.032
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.032
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.032
|
Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.032
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.032
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.032
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.032
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.032
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.032
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.032
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.032
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.032
|
Mouse |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.032
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.032
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.032
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.031
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.031
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.031
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.031
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.031
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.030
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.030
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.030
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.030
|
|
|
|
antigen processing and presentation of exogenous peptide antigen
|
GO:0002478 |
21 |
0.030
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.030
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.030
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
22 |
0.030
|
Rat |
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.030
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.030
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.029
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.029
|
|
|
|
myeloid leukocyte cytokine production
|
GO:0061082 |
12 |
0.029
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.029
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.029
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.029
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.029
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.029
|
Mouse |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.029
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.029
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.028
|
Mouse |
|
|
compound eye development
|
GO:0048749 |
1 |
0.028
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.028
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.028
|
|
|
|
positive regulation of vasculogenesis
|
GO:2001214 |
7 |
0.028
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.028
|
Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.028
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.028
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.028
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.028
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.028
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.028
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.027
|
|
|
|
antigen processing and presentation of exogenous antigen
|
GO:0019884 |
26 |
0.027
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.027
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.027
|
|
|
|
organ regeneration
|
GO:0031100 |
2 |
0.027
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.027
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.027
|
Mouse |
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.027
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.027
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.027
|
Mouse |
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.027
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.027
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.027
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.027
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.027
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.027
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.027
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.027
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.027
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.026
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.026
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.026
|
|
|
|
ventral trunk neural crest cell migration
|
GO:0036486 |
4 |
0.026
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.026
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.026
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.026
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.026
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.026
|
Human Mouse |
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
4 |
0.026
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.026
|
|
|
|
sympathetic neuron projection guidance
|
GO:0097491 |
4 |
0.026
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.026
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.026
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.026
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.026
|
|
|
|
sympathetic neuron projection extension
|
GO:0097490 |
4 |
0.026
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.026
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.026
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.025
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.025
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.025
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.025
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.025
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.025
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.025
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.025
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.025
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.024
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.024
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.024
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
35 |
0.024
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.024
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.024
|
Rat |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.024
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.024
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.024
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.024
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.024
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.024
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.024
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.024
|
Rat |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.024
|
|
|
|
memory
|
GO:0007613 |
58 |
0.024
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.023
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.023
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.023
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.023
|
Mouse |
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.023
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.023
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.023
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.023
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.023
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.023
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.023
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.022
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.022
|
Mouse |
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.022
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.022
|
Mouse |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.022
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.022
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.022
|
Human Mouse |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.022
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.022
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.022
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.022
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.022
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.022
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.022
|
Mouse |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.022
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.022
|
|
|
|
vascular smooth muscle cell differentiation
|
GO:0035886 |
11 |
0.022
|
|
|
|
artery development
|
GO:0060840 |
53 |
0.022
|
Zebrafish |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.021
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.021
|
|
|
|
serotonin secretion by platelet
|
GO:0002554 |
3 |
0.021
|
|
|
|
heparin biosynthetic process
|
GO:0030210 |
2 |
0.021
|
|
|
|
platelet degranulation
|
GO:0002576 |
6 |
0.021
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
26 |
0.021
|
Mouse |
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
37 |
0.021
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.021
|
Mouse |
|
|
forebrain development
|
GO:0030900 |
302 |
0.021
|
Mouse |
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.021
|
|
|
|
gonadotrophin releasing hormone neuronal migration to the hypothalamus
|
GO:0021828 |
3 |
0.021
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.021
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.021
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.021
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.021
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.021
|
Mouse |
|
|
negative regulation of intracellular transport
|
GO:0032387 |
38 |
0.021
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.021
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.020
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.020
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.020
|
|
|
|
negative adaptation of signaling pathway
|
GO:0022401 |
5 |
0.020
|
|
|
|
embryonic placenta morphogenesis
|
GO:0060669 |
25 |
0.020
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.020
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.020
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.020
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.020
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.020
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.020
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.020
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
22 |
0.020
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.020
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.020
|
Mouse |
|
|
blood coagulation
|
GO:0007596 |
76 |
0.020
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.020
|
|
|
|
positive regulation of type iii hypersensitivity
|
GO:0001805 |
3 |
0.020
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.020
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.020
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.020
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.020
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.020
|
Human |
|
|
bone remodeling
|
GO:0046849 |
53 |
0.020
|
Mouse |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.020
|
|
|
|
monoamine transport
|
GO:0015844 |
33 |
0.020
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.020
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.020
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.020
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
25 |
0.020
|
Mouse |
|
|
segmentation
|
GO:0035282 |
93 |
0.020
|
Zebrafish |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.020
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.019
|
|
|
|
glycosylation
|
GO:0070085 |
62 |
0.019
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.019
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.019
|
|
|
|
establishment of neuroblast polarity
|
GO:0045200 |
1 |
0.019
|
|
|
|
operant conditioning
|
GO:0035106 |
2 |
0.019
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.019
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.019
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.019
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.019
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.019
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.019
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.019
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.019
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.019
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.019
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.019
|
Mouse |
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.019
|
Mouse |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.019
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.018
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.018
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.018
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.018
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.018
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.018
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.018
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.018
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.018
|
|
|
|
antigen processing and presentation of peptide antigen via mhc class i
|
GO:0002474 |
9 |
0.018
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.018
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.018
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.018
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.018
|
|
|
|
neutrophil activation
|
GO:0042119 |
9 |
0.018
|
|
