|
positive regulation of peptide secretion
|
GO:0002793 |
33 |
0.763
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.636
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.516
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.472
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.465
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.389
|
|
|
regulation of integrin biosynthetic process
|
GO:0045113 |
1 |
0.364
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
4 |
0.355
|
|
|
integrin biosynthetic process
|
GO:0045112 |
1 |
0.313
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.296
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.274
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.238
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.182
|
|
|
cation transport
|
GO:0006812 |
399 |
0.176
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.151
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.150
|
|
|
cognition
|
GO:0050890 |
149 |
0.147
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.146
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.137
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.125
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.122
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.119
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.106
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.102
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.100
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.099
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.092
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.092
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.085
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.082
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.081
|
|
|
memory
|
GO:0007613 |
58 |
0.079
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.075
|
|
|
amide transport
|
GO:0042886 |
138 |
0.074
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.073
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.066
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.065
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.064
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.063
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.061
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.057
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.056
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.056
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.055
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.054
|
|
|
circadian sleep wake cycle rem sleep
|
GO:0042747 |
1 |
0.053
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.051
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.050
|
|
|
protein processing
|
GO:0016485 |
163 |
0.049
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.045
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.045
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.044
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.044
|
|
|
regulation of cation channel activity
|
GO:2001257 |
22 |
0.042
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.040
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.040
|
|
|
positive regulation of voltage gated calcium channel activity
|
GO:1901387 |
2 |
0.039
|
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
20 |
0.038
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.038
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.037
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.036
|
|
|
membrane raft assembly
|
GO:0001765 |
3 |
0.036
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.035
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.035
|
|
|
organelle membrane fusion
|
GO:0090174 |
1 |
0.033
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.032
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.032
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.031
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
4 |
0.029
|
|
|
regulation of calcium ion transmembrane transport
|
GO:1903169 |
20 |
0.028
|
|
|
autophagic vacuole fusion
|
GO:0000046 |
1 |
0.028
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.028
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.027
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.027
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
15 |
0.027
|
|
|
maintenance of epithelial cell apical basal polarity
|
GO:0045199 |
2 |
0.027
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.026
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.026
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
46 |
0.025
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.025
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.024
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
24 |
0.024
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.024
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.024
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.024
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.024
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.023
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.023
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.023
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.023
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.023
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.023
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.022
|
|
|
entry into cell of other organism involved in symbiotic interaction
|
GO:0051806 |
15 |
0.022
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.022
|
|
|
vesicle fusion
|
GO:0006906 |
16 |
0.022
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.022
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.022
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.021
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.021
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.020
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.020
|
|
|
carbon catabolite regulation of transcription
|
GO:0045990 |
4 |
0.020
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.020
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.020
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.020
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.020
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.020
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.020
|
|
|
type b pancreatic cell proliferation
|
GO:0044342 |
10 |
0.020
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.020
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.020
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.019
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.019
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.019
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.019
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.019
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.019
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.019
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.018
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.018
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.018
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.018
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.018
|
|
|
regulation of neutrophil apoptotic process
|
GO:0033029 |
1 |
0.018
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.018
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.018
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.018
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.018
|
|
|
detection of muscle stretch
|
GO:0035995 |
1 |
0.018
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.018
|
|
|
entry into host
|
GO:0044409 |
15 |
0.017
|
|
|
maintenance of apical basal cell polarity
|
GO:0035090 |
3 |
0.017
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.017
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.017
|
|
|
response to muscle stretch
|
GO:0035994 |
1 |
0.017
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.017
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.017
|
|
|
cellular response to hepatocyte growth factor stimulus
|
GO:0035729 |
2 |
0.017
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.017
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.017
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.017
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.016
|
|
|
plasma cell differentiation
|
GO:0002317 |
3 |
0.016
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.016
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.016
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
29 |
0.016
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.016
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.016
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.016
|
|
|
entry into other organism involved in symbiotic interaction
|
GO:0051828 |
15 |
0.016
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.016
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.016
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.016
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.016
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.016
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.016
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.016
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.016
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.016
|
|
|
positive regulation of calcium ion transmembrane transporter activity
|
GO:1901021 |
8 |
0.016
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.016
|
|
|
cellular response to antibiotic
|
GO:0071236 |
4 |
0.015
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.015
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.015
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.015
|
Mouse |
|
inflammatory response
|
GO:0006954 |
244 |
0.015
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.015
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.015
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.015
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.015
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.015
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.015
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.015
|
|
|
positive regulation of rac protein signal transduction
|
GO:0035022 |
1 |
0.015
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.015
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.014
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.014
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.014
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.014
|
|
|
entry into host cell
|
GO:0030260 |
15 |
0.014
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.014
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.014
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.014
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.014
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.014
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.014
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.013
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.013
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.013
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.013
|
|
|
negative regulation of immunological synapse formation
|
GO:2000521 |
1 |
0.013
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.013
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.013
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.013
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.013
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.013
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.013
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.013
|
|
|
negative regulation of glycoprotein metabolic process
|
GO:1903019 |
3 |
0.013
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.013
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.013
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.013
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.013
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.013
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.013
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.012
|
Human |
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.012
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.012
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.012
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.012
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.012
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.012
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.012
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.012
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.012
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.012
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.012
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.012
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.012
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.012
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.012
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.012
|
|
|
primitive erythrocyte differentiation
|
GO:0060319 |
3 |
0.012
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.012
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.012
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.012
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.012
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.011
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.011
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.011
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.011
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.011
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.011
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.011
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.011
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.011
|
|
|
glycoprotein catabolic process
|
GO:0006516 |
5 |
0.011
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.011
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.011
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.011
|
|
|
movement in environment of other organism involved in symbiotic interaction
|
GO:0052192 |
15 |
0.011
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.011
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.011
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.011
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.011
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.011
|
|
|
action potential
|
GO:0001508 |
78 |
0.011
|
|
|
interaction with host
|
GO:0051701 |
22 |
0.011
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.011
|
|
|
fibril organization
|
GO:0097435 |
2 |
0.011
|
|
|
lung development
|
GO:0030324 |
164 |
0.011
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.011
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.011
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.011
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.011
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.011
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.011
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.011
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.011
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.010
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.010
|
|
|
heart process
|
GO:0003015 |
94 |
0.010
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
27 |
0.010
|
|
|
ossification
|
GO:0001503 |
216 |
0.010
|
|
|
response to calcium ion
|
GO:0051592 |
20 |
0.010
|
Mouse |
|
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell
|
GO:0002291 |
2 |
0.010
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.010
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.010
|
|