Mus musculus

45 known processes

Smyd2

SET and MYND domain containing 2

(Aliases: Zmynd14,1110020E07Rik,4930402C15,KMT3C)

Smyd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation or removal GO:0070647 207 0.120
protein modification by small protein conjugation GO:0032446 187 0.080
protein ubiquitination GO:0016567 171 0.066
nucleobase containing small molecule metabolic process GO:0055086 352 0.064
cellular amine metabolic process GO:0044106 44 0.060
nucleotide metabolic process GO:0009117 332 0.058
amine metabolic process GO:0009308 45 0.051
negative regulation of protein metabolic process GO:0051248 282 0.049
Mouse
negative regulation of molecular function GO:0044092 258 0.047
Mouse
cellular protein catabolic process GO:0044257 155 0.045
cytokine production GO:0001816 319 0.044
positive regulation of protein modification process GO:0031401 299 0.042
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.041
regulation of cellular amine metabolic process GO:0033238 20 0.041
spermatogenesis GO:0007283 284 0.039
male gamete generation GO:0048232 285 0.039
regulation of transferase activity GO:0051338 263 0.038
Mouse
cation transport GO:0006812 399 0.038
response to organonitrogen compound GO:0010243 246 0.036
cellular ketone metabolic process GO:0042180 84 0.036
mitochondrion organization GO:0007005 134 0.036
regulation of hydrolase activity GO:0051336 246 0.035
leukocyte differentiation GO:0002521 342 0.035
apoptotic signaling pathway GO:0097190 306 0.033
negative regulation of intracellular signal transduction GO:1902532 167 0.033
regulation of protein kinase activity GO:0045859 232 0.033
Mouse
macromolecule catabolic process GO:0009057 281 0.032
glycosyl compound metabolic process GO:1901657 246 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.029
dna metabolic process GO:0006259 303 0.029
Mouse
cellular homeostasis GO:0019725 240 0.029
cellular amino acid metabolic process GO:0006520 103 0.028
rho protein signal transduction GO:0007266 32 0.028
epithelial tube morphogenesis GO:0060562 303 0.028
organophosphate biosynthetic process GO:0090407 122 0.027
positive regulation of programmed cell death GO:0043068 218 0.027
signal transduction involved in dna damage checkpoint GO:0072422 3 0.027
transmembrane transport GO:0055085 412 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
purine containing compound metabolic process GO:0072521 311 0.026
protein polyubiquitination GO:0000209 33 0.026
regulation of secretion GO:0051046 274 0.025
small gtpase mediated signal transduction GO:0007264 97 0.025
regulation of response to wounding GO:1903034 189 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
Mouse
regulation of ion transport GO:0043269 215 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
regulation of cellular amino acid metabolic process GO:0006521 5 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
Mouse
negative regulation of protein modification process GO:0031400 163 0.023
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.023
negative regulation of transferase activity GO:0051348 85 0.023
Mouse
regulation of membrane potential GO:0042391 192 0.023
regulation of cytokine production GO:0001817 266 0.022
intrinsic apoptotic signaling pathway GO:0097193 132 0.022
cellular response to dna damage stimulus GO:0006974 207 0.022
Human
ras protein signal transduction GO:0007265 77 0.022
wnt signaling pathway GO:0016055 188 0.022
cation transmembrane transport GO:0098655 266 0.021
immune effector process GO:0002252 321 0.021
peptidyl amino acid modification GO:0018193 336 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
regulation of feeding behavior GO:0060259 3 0.021
carbohydrate metabolic process GO:0005975 230 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
cellular lipid metabolic process GO:0044255 323 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
ion transmembrane transport GO:0034220 361 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
positive regulation of cell migration GO:0030335 109 0.020
inflammatory response GO:0006954 244 0.020
regulation of cell motility GO:2000145 236 0.020
organic cyclic compound catabolic process GO:1901361 295 0.019
positive regulation of cell death GO:0010942 224 0.019
regulation of cell growth GO:0001558 91 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
aromatic compound catabolic process GO:0019439 286 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.019
Mouse
regulation of kinase activity GO:0043549 249 0.019
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
intracellular protein transport GO:0006886 204 0.018
regulation of secretion by cell GO:1903530 249 0.018
regulation of protein localization GO:0032880 231 0.018
protein catabolic process GO:0030163 221 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
wound healing GO:0042060 157 0.018
regulation of transmembrane transport GO:0034762 128 0.018
epithelial cell proliferation GO:0050673 174 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.017
axonogenesis GO:0007409 274 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
Mouse
positive regulation of organelle organization GO:0010638 128 0.017
regulation of cell migration GO:0030334 219 0.017
protein processing GO:0016485 163 0.017
protein localization to organelle GO:0033365 185 0.017
response to inorganic substance GO:0010035 96 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
cellular protein complex assembly GO:0043623 116 0.017
cell type specific apoptotic process GO:0097285 268 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.017
positive regulation of cell development GO:0010720 237 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
connective tissue development GO:0061448 179 0.017
oxidation reduction process GO:0055114 342 0.017
sensory perception GO:0007600 245 0.017
membrane organization GO:0061024 245 0.017
lipid biosynthetic process GO:0008610 179 0.017
ribose phosphate metabolic process GO:0019693 291 0.016
neuron apoptotic process GO:0051402 142 0.016
positive regulation of cell motility GO:2000147 116 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
regulation of defense response GO:0031347 233 0.016
organic acid biosynthetic process GO:0016053 86 0.016
modification dependent protein catabolic process GO:0019941 133 0.016
regulation of organelle organization GO:0033043 289 0.016
Zebrafish
response to extracellular stimulus GO:0009991 127 0.016
cytoplasmic transport GO:0016482 234 0.016
ketone catabolic process GO:0042182 3 0.016
regulation of protein catabolic process GO:0042176 108 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
Mouse
carboxylic acid biosynthetic process GO:0046394 86 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
fat cell differentiation GO:0045444 160 0.016
positive regulation of cytokine production GO:0001819 174 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
mapk cascade GO:0000165 281 0.015
development of primary sexual characteristics GO:0045137 143 0.015
heterocycle catabolic process GO:0046700 280 0.015
cell growth GO:0016049 130 0.015
organophosphate catabolic process GO:0046434 232 0.015
spermatid development GO:0007286 108 0.015
respiratory system development GO:0060541 190 0.015
adult behavior GO:0030534 135 0.015
negative regulation of neuron apoptotic process GO:0043524 92 0.015
neurotransmitter transport GO:0006836 76 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
anatomical structure homeostasis GO:0060249 145 0.015
homeostasis of number of cells GO:0048872 210 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
regulation of transporter activity GO:0032409 57 0.014
regulation of hormone levels GO:0010817 211 0.014
regulation of mapk cascade GO:0043408 248 0.014
protein modification by small protein removal GO:0070646 21 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
regulation of peptidase activity GO:0052547 96 0.014
small molecule biosynthetic process GO:0044283 132 0.014
regulation of neuron differentiation GO:0045664 281 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
protein localization to nucleus GO:0034504 121 0.014
synaptic transmission GO:0007268 329 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
regulation of neurotransmitter levels GO:0001505 87 0.014
urogenital system development GO:0001655 261 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
leukocyte migration GO:0050900 124 0.014
ameboidal type cell migration GO:0001667 128 0.014
lymphocyte differentiation GO:0030098 242 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
forebrain development GO:0030900 302 0.014
organic hydroxy compound transport GO:0015850 93 0.014
t cell activation GO:0042110 289 0.014
divalent metal ion transport GO:0070838 172 0.014
response to oxidative stress GO:0006979 123 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
positive regulation of apoptotic signaling pathway GO:2001235 95 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
innate immune response GO:0045087 157 0.013
response to peptide GO:1901652 136 0.013
steroid metabolic process GO:0008202 119 0.013
germ cell development GO:0007281 185 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
regulation of cell cycle GO:0051726 281 0.013
ovulation cycle GO:0042698 59 0.013
regulation of proteolysis GO:0030162 164 0.013
regulation of intracellular transport GO:0032386 159 0.013
renal system development GO:0072001 225 0.013
maintenance of location GO:0051235 89 0.013
protein dna complex subunit organization GO:0071824 28 0.013
Mouse
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.013
immune response activating signal transduction GO:0002757 116 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
regulation of protein transport GO:0051223 163 0.013
transmission of nerve impulse GO:0019226 76 0.013
macromolecule methylation GO:0043414 120 0.012
dephosphorylation GO:0016311 129 0.012
regulation of inflammatory response GO:0050727 147 0.012
action potential GO:0001508 78 0.012
muscle cell differentiation GO:0042692 261 0.012
Zebrafish Mouse
striated muscle tissue development GO:0014706 293 0.012
Zebrafish Mouse
multicellular organismal signaling GO:0035637 91 0.012
activation of adenylate cyclase activity GO:0007190 4 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of homeostatic process GO:0032844 182 0.012
positive regulation of transferase activity GO:0051347 167 0.012
negative regulation of kinase activity GO:0033673 81 0.012
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.012
alcohol metabolic process GO:0006066 116 0.012
nucleotide catabolic process GO:0009166 217 0.012
regulation of cell activation GO:0050865 289 0.012
muscle tissue development GO:0060537 308 0.012
Zebrafish Mouse
nucleotide biosynthetic process GO:0009165 78 0.012
negative regulation of neuron death GO:1901215 98 0.012
metal ion homeostasis GO:0055065 189 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
response to endoplasmic reticulum stress GO:0034976 53 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
response to peptide hormone GO:0043434 127 0.012
nitrogen compound transport GO:0071705 271 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
rhodopsin mediated signaling pathway GO:0016056 4 0.012
nuclear transport GO:0051169 139 0.012
striated muscle cell development GO:0055002 125 0.012
Zebrafish Mouse
cellular macromolecule catabolic process GO:0044265 206 0.012
organelle assembly GO:0070925 177 0.012
Zebrafish
response to nutrient levels GO:0031667 109 0.012
endocytosis GO:0006897 168 0.012
regulation of map kinase activity GO:0043405 120 0.012
regulation of neuron death GO:1901214 134 0.012
nucleoside metabolic process GO:0009116 246 0.012
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.012
methylation GO:0032259 134 0.011
interleukin 8 production GO:0032637 4 0.011
chemotaxis GO:0006935 247 0.011
branching morphogenesis of an epithelial tube GO:0048754 159 0.011
epithelial cell development GO:0002064 159 0.011
cell activation involved in immune response GO:0002263 126 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
intracellular receptor signaling pathway GO:0030522 74 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
small molecule catabolic process GO:0044282 71 0.011
gonad development GO:0008406 141 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
locomotory behavior GO:0007626 195 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
regulation of body fluid levels GO:0050878 162 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
skin development GO:0043588 220 0.011
glycoprotein metabolic process GO:0009100 116 0.011
lung development GO:0030324 164 0.011
lateral inhibition GO:0046331 1 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
t cell differentiation GO:0030217 174 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
nucleoside catabolic process GO:0009164 206 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.011
regulation of anatomical structure size GO:0090066 178 0.011
protein import GO:0017038 101 0.011
signal transduction by p53 class mediator GO:0072331 51 0.011
Human
actin cytoskeleton organization GO:0030036 220 0.011
Zebrafish
double strand break repair via nonhomologous end joining GO:0006303 10 0.011
protein targeting GO:0006605 143 0.011
cellular modified amino acid metabolic process GO:0006575 63 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
cellular response to lipid GO:0071396 145 0.011
Mouse
gland development GO:0048732 330 0.011
camera type eye development GO:0043010 266 0.010
organelle localization GO:0051640 179 0.010
regulation of binding GO:0051098 111 0.010
response to acid chemical GO:0001101 111 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010
positive regulation of kinase activity GO:0033674 155 0.010
regulation of protein ubiquitination GO:0031396 52 0.010
response to lipopolysaccharide GO:0032496 128 0.010
respiratory tube development GO:0030323 167 0.010
chromatin organization GO:0006325 206 0.010
purine nucleotide biosynthetic process GO:0006164 65 0.010
protein maturation GO:0051604 176 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
neuron death GO:0070997 154 0.010
adult locomotory behavior GO:0008344 91 0.010
spermatid differentiation GO:0048515 115 0.010
immune response regulating signaling pathway GO:0002764 125 0.010
organonitrogen compound catabolic process GO:1901565 264 0.010
b cell activation GO:0042113 161 0.010
regulation of cell cycle process GO:0010564 160 0.010
endomembrane system organization GO:0010256 147 0.010
dna replication independent nucleosome assembly GO:0006336 1 0.010
negative regulation of cytokine production GO:0001818 84 0.010
fertilization GO:0009566 127 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
blood circulation GO:0008015 195 0.010
Zebrafish

Smyd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.042
central nervous system disease DOID:331 0 0.025
neurodegenerative disease DOID:1289 0 0.025