Mus musculus

37 known processes

Lipa

lysosomal acid lipase A

(Aliases: Lal,Lip1,AA960673,Lip-1)

Lipa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.259
lipid catabolic process GO:0016042 69 0.251
Worm
cellular protein catabolic process GO:0044257 155 0.214
amine metabolic process GO:0009308 45 0.205
cellular amino acid metabolic process GO:0006520 103 0.176
cellular lipid metabolic process GO:0044255 323 0.175
Worm
regulation of cellular ketone metabolic process GO:0010565 66 0.172
glycerolipid metabolic process GO:0046486 122 0.171
Worm
macromolecule catabolic process GO:0009057 281 0.170
protein catabolic process GO:0030163 221 0.167
organonitrogen compound catabolic process GO:1901565 264 0.161
defense response to other organism GO:0098542 197 0.157
Worm
innate immune response GO:0045087 157 0.157
regulation of body fluid levels GO:0050878 162 0.152
peptidyl amino acid modification GO:0018193 336 0.150
cellular amine metabolic process GO:0044106 44 0.143
regulation of membrane potential GO:0042391 192 0.142
cation transport GO:0006812 399 0.134
transmembrane transport GO:0055085 412 0.134
carbohydrate metabolic process GO:0005975 230 0.130
cellular ketone metabolic process GO:0042180 84 0.126
regulation of cellular amine metabolic process GO:0033238 20 0.125
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.122
regulation of defense response GO:0031347 233 0.121
developmental maturation GO:0021700 193 0.120
vacuole organization GO:0007033 38 0.119
circulatory system process GO:0003013 197 0.117
ion transmembrane transport GO:0034220 361 0.117
epidermis development GO:0008544 187 0.113
mapk cascade GO:0000165 281 0.112
leukocyte differentiation GO:0002521 342 0.111
dna metabolic process GO:0006259 303 0.111
nucleobase containing small molecule metabolic process GO:0055086 352 0.109
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.106
wound healing GO:0042060 157 0.105
gland development GO:0048732 330 0.104
cellular macromolecule catabolic process GO:0044265 206 0.102
regulation of cellular amino acid metabolic process GO:0006521 5 0.101
skin development GO:0043588 220 0.100
positive regulation of mapk cascade GO:0043410 170 0.099
inflammatory response GO:0006954 244 0.097
regulation of cytokine production GO:0001817 266 0.094
positive regulation of protein modification process GO:0031401 299 0.092
sensory perception of umami taste GO:0050917 4 0.092
coagulation GO:0050817 78 0.090
cellular ion homeostasis GO:0006873 165 0.087
anion transport GO:0006820 177 0.086
organophosphate biosynthetic process GO:0090407 122 0.084
cholesterol storage GO:0010878 4 0.084
fatty acid metabolic process GO:0006631 121 0.083
metal ion homeostasis GO:0055065 189 0.083
purine nucleoside triphosphate metabolic process GO:0009144 226 0.081
organophosphate catabolic process GO:0046434 232 0.081
regulation of lipid metabolic process GO:0019216 118 0.080
locomotory behavior GO:0007626 195 0.080
regulation of reactive oxygen species metabolic process GO:2000377 40 0.080
regulation of innate immune response GO:0045088 91 0.079
epithelial cell proliferation GO:0050673 174 0.079
tissue homeostasis GO:0001894 115 0.079
maintenance of location GO:0051235 89 0.078
Worm
aromatic compound catabolic process GO:0019439 286 0.078
regulation of map kinase activity GO:0043405 120 0.077
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.077
lipid transport GO:0006869 98 0.076
organic hydroxy compound transport GO:0015850 93 0.076
nucleotide metabolic process GO:0009117 332 0.075
pigmentation GO:0043473 71 0.075
nucleoside phosphate metabolic process GO:0006753 338 0.074
monosaccharide metabolic process GO:0005996 106 0.074
regulation of cellular catabolic process GO:0031329 242 0.073
Worm
regulation of kinase activity GO:0043549 249 0.073
lipid localization GO:0010876 126 0.073
Worm
male gamete generation GO:0048232 285 0.073
skeletal system development GO:0001501 356 0.072
cellular homeostasis GO:0019725 240 0.072
t cell activation GO:0042110 289 0.072
positive regulation of innate immune response GO:0045089 80 0.071
morphogenesis of a branching epithelium GO:0061138 193 0.071
sensory perception GO:0007600 245 0.071
regulation of vesicle mediated transport GO:0060627 139 0.071
regulation of nitrogen cycle metabolic process GO:1903314 1 0.070
purine nucleotide metabolic process GO:0006163 302 0.070
positive regulation of phagocytosis engulfment GO:0060100 3 0.069
purine nucleoside metabolic process GO:0042278 241 0.066
cellular lipid catabolic process GO:0044242 52 0.066
Worm
apoptotic signaling pathway GO:0097190 306 0.065
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.065
positive regulation of fatty acid oxidation GO:0046321 4 0.064
positive regulation of lymphocyte activation GO:0051251 140 0.064
regulation of canonical wnt signaling pathway GO:0060828 82 0.064
wnt signaling pathway GO:0016055 188 0.064
cytokine production GO:0001816 319 0.063
monocarboxylic acid metabolic process GO:0032787 191 0.063
response to oxidative stress GO:0006979 123 0.062
regulation of cell activation GO:0050865 289 0.062
cellular nitrogen compound catabolic process GO:0044270 280 0.060
cellular response to hormone stimulus GO:0032870 150 0.060
myeloid leukocyte differentiation GO:0002573 119 0.060
placenta development GO:0001890 140 0.060
blood vessel morphogenesis GO:0048514 285 0.059
carbohydrate derivative catabolic process GO:1901136 231 0.059
cell substrate adhesion GO:0031589 130 0.059
defense response to bacterium GO:0042742 119 0.058
Worm
positive regulation of cellular amine metabolic process GO:0033240 5 0.058
purine containing compound biosynthetic process GO:0072522 70 0.058
regulation of intracellular transport GO:0032386 159 0.058
purine nucleoside triphosphate catabolic process GO:0009146 203 0.057
lipid biosynthetic process GO:0008610 179 0.056
endocytosis GO:0006897 168 0.056
organic acid transport GO:0015849 101 0.056
positive regulation of defense response GO:0031349 124 0.056
modification dependent protein catabolic process GO:0019941 133 0.056
regulation of mapk cascade GO:0043408 248 0.055
negative regulation of growth GO:0045926 99 0.055
cation homeostasis GO:0055080 212 0.055
purine containing compound metabolic process GO:0072521 311 0.055
ribose phosphate metabolic process GO:0019693 291 0.055
regulation of organelle organization GO:0033043 289 0.055
negative regulation of transferase activity GO:0051348 85 0.054
cellular response to lipid GO:0071396 145 0.054
vitamin metabolic process GO:0006766 23 0.054
ribose phosphate biosynthetic process GO:0046390 59 0.054
ribonucleotide metabolic process GO:0009259 291 0.054
regulation of transferase activity GO:0051338 263 0.054
regulation of protein kinase activity GO:0045859 232 0.053
regulation of leukocyte mediated immunity GO:0002703 104 0.053
forebrain development GO:0030900 302 0.053
regulation of lymphocyte activation GO:0051249 240 0.053
response to nutrient levels GO:0031667 109 0.052
Worm
regulation of cell migration GO:0030334 219 0.052
regulation of response to wounding GO:1903034 189 0.052
purine nucleotide biosynthetic process GO:0006164 65 0.051
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.051
negative regulation of cell proliferation GO:0008285 296 0.051
nucleoside catabolic process GO:0009164 206 0.051
multicellular organism growth GO:0035264 161 0.051
reactive oxygen species biosynthetic process GO:1903409 8 0.051
phospholipid transfer to membrane GO:0006649 2 0.051
regulation of organ morphogenesis GO:2000027 144 0.051
regulation of apoptotic signaling pathway GO:2001233 197 0.050
nucleoside metabolic process GO:0009116 246 0.050
cellular metal ion homeostasis GO:0006875 151 0.050
regulation of protein catabolic process GO:0042176 108 0.049
transmission of nerve impulse GO:0019226 76 0.049
angiogenesis GO:0001525 201 0.049
spermatogenesis GO:0007283 284 0.049
anatomical structure homeostasis GO:0060249 145 0.049
lipid storage GO:0019915 36 0.049
Worm
monocarboxylic acid catabolic process GO:0072329 27 0.049
canonical wnt signaling pathway GO:0060070 130 0.048
carbohydrate derivative biosynthetic process GO:1901137 183 0.048
lipid modification GO:0030258 65 0.048
organic cyclic compound catabolic process GO:1901361 295 0.048
regulation of response to oxidative stress GO:1902882 19 0.047
organic anion transport GO:0015711 137 0.047
myeloid cell differentiation GO:0030099 233 0.047
carboxylic acid transport GO:0046942 100 0.046
tissue remodeling GO:0048771 102 0.046
negative regulation of intracellular signal transduction GO:1902532 167 0.046
purine ribonucleotide metabolic process GO:0009150 290 0.046
cell adhesion GO:0007155 329 0.046
purine ribonucleoside metabolic process GO:0046128 241 0.046
nitrogen compound transport GO:0071705 271 0.046
small molecule catabolic process GO:0044282 71 0.046
fat soluble vitamin biosynthetic process GO:0042362 4 0.046
multicellular organismal homeostasis GO:0048871 164 0.046
ear development GO:0043583 200 0.045
hair follicle development GO:0001942 85 0.044
regulation of blood pressure GO:0008217 93 0.044
hormone metabolic process GO:0042445 86 0.044
purine ribonucleotide catabolic process GO:0009154 208 0.044
positive regulation of phagocytosis GO:0050766 26 0.044
glycosyl compound metabolic process GO:1901657 246 0.044
ribonucleotide catabolic process GO:0009261 208 0.043
nucleoside phosphate biosynthetic process GO:1901293 79 0.043
ribonucleotide biosynthetic process GO:0009260 59 0.043
negative regulation of phosphorus metabolic process GO:0010563 184 0.043
ribonucleoside catabolic process GO:0042454 206 0.043
cellular response to starvation GO:0009267 57 0.043
Worm
cellular calcium ion homeostasis GO:0006874 119 0.043
regulation of endocytosis GO:0030100 69 0.043
epithelial tube morphogenesis GO:0060562 303 0.043
response to organic cyclic compound GO:0014070 198 0.043
regulation of protein serine threonine kinase activity GO:0071900 157 0.042
cellular response to organonitrogen compound GO:0071417 145 0.042
regulation of wnt signaling pathway GO:0030111 123 0.042
skeletal system morphogenesis GO:0048705 203 0.042
organelle localization GO:0051640 179 0.042
cellular chemical homeostasis GO:0055082 215 0.042
lysosome organization GO:0007040 21 0.042
lytic vacuole organization GO:0080171 21 0.041
ribonucleoside metabolic process GO:0009119 245 0.041
organic hydroxy compound metabolic process GO:1901615 203 0.041
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.041
nucleotide catabolic process GO:0009166 217 0.041
sulfur compound metabolic process GO:0006790 100 0.041
neuronal action potential GO:0019228 54 0.041
regulation of fatty acid metabolic process GO:0019217 28 0.041
detection of stimulus GO:0051606 84 0.041
cellular carbohydrate metabolic process GO:0044262 119 0.041
blood coagulation GO:0007596 76 0.040
calcium ion homeostasis GO:0055074 127 0.040
cation transmembrane transport GO:0098655 266 0.040
ubiquitin dependent protein catabolic process GO:0006511 129 0.040
organonitrogen compound biosynthetic process GO:1901566 192 0.040
heterocycle catabolic process GO:0046700 280 0.040
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.040
single organismal cell cell adhesion GO:0016337 131 0.040
regulation of myeloid leukocyte differentiation GO:0002761 58 0.040
eye photoreceptor cell differentiation GO:0001754 41 0.040
cellular response to thyroid hormone stimulus GO:0097067 1 0.040
blood circulation GO:0008015 195 0.040
ras protein signal transduction GO:0007265 77 0.039
regulation of system process GO:0044057 200 0.039
purine nucleotide catabolic process GO:0006195 211 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.039
purine nucleoside catabolic process GO:0006152 205 0.039
divalent inorganic cation homeostasis GO:0072507 138 0.038
cellular response to external stimulus GO:0071496 88 0.038
Worm
ameboidal type cell migration GO:0001667 128 0.038
activation of adenylate cyclase activity GO:0007190 4 0.038
response to organonitrogen compound GO:0010243 246 0.038
cell maturation GO:0048469 127 0.038
branching morphogenesis of an epithelial tube GO:0048754 159 0.038
reactive oxygen species metabolic process GO:0072593 84 0.038
positive regulation of endocytosis GO:0045807 42 0.038
purine ribonucleotide biosynthetic process GO:0009152 59 0.038
rho protein signal transduction GO:0007266 32 0.038
receptor mediated endocytosis GO:0006898 51 0.037
ribonucleoside triphosphate catabolic process GO:0009203 199 0.037
ribonucleoside triphosphate metabolic process GO:0009199 220 0.037
nucleoside phosphate catabolic process GO:1901292 222 0.037
epithelial cell development GO:0002064 159 0.037
gliogenesis GO:0042063 141 0.037
phospholipid metabolic process GO:0006644 87 0.036
regulation of protein transport GO:0051223 163 0.036
peptide metabolic process GO:0006518 46 0.036
single organism cell adhesion GO:0098602 156 0.036
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.036
nucleotide biosynthetic process GO:0009165 78 0.035
nucleoside triphosphate metabolic process GO:0009141 230 0.035
negative regulation of immune system process GO:0002683 209 0.035
positive regulation of leukocyte differentiation GO:1902107 86 0.035
divalent inorganic cation transport GO:0072511 178 0.035
glycosyl compound catabolic process GO:1901658 206 0.035
positive regulation of kinase activity GO:0033674 155 0.035
immune effector process GO:0002252 321 0.035
embryonic organ morphogenesis GO:0048562 276 0.035
hemostasis GO:0007599 78 0.034
purine containing compound catabolic process GO:0072523 213 0.034
lipid oxidation GO:0034440 29 0.034
connective tissue development GO:0061448 179 0.034
regulation of t cell activation GO:0050863 170 0.034
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.034
adult behavior GO:0030534 135 0.034
response to starvation GO:0042594 65 0.034
Worm
stem cell differentiation GO:0048863 268 0.033
cell fate commitment GO:0045165 210 0.033
regulation of cell growth GO:0001558 91 0.033
mitochondrion organization GO:0007005 134 0.033
photoreceptor cell differentiation GO:0046530 52 0.033
cognition GO:0050890 149 0.033
regulation of leukocyte differentiation GO:1902105 159 0.033
nucleoside triphosphate catabolic process GO:0009143 205 0.033
small gtpase mediated signal transduction GO:0007264 97 0.033
peptidyl tyrosine phosphorylation GO:0018108 143 0.033
regulation of epithelial cell proliferation GO:0050678 141 0.033
regulation of cellular response to stress GO:0080135 159 0.033
Worm
response to growth factor GO:0070848 198 0.033
synaptic transmission GO:0007268 329 0.033
regulation of hydrolase activity GO:0051336 246 0.032
nucleoside monophosphate metabolic process GO:0009123 85 0.032
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.032
reactive nitrogen species metabolic process GO:2001057 0 0.032
gonad development GO:0008406 141 0.032
alcohol metabolic process GO:0006066 116 0.032
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.032
regulation of secretion GO:0051046 274 0.032
protein localization to organelle GO:0033365 185 0.032
regulation of inflammatory response GO:0050727 147 0.032
positive regulation of cytokine production GO:0001819 174 0.031
glucose homeostasis GO:0042593 128 0.031
lymphocyte mediated immunity GO:0002449 139 0.031
autophagy GO:0006914 45 0.031
Worm
positive regulation of immune effector process GO:0002699 107 0.031
hexose metabolic process GO:0019318 98 0.031
negative regulation of protein modification process GO:0031400 163 0.031
cellular divalent inorganic cation homeostasis GO:0072503 127 0.031
regulation of secretion by cell GO:1903530 249 0.031
lung development GO:0030324 164 0.031
leukocyte mediated immunity GO:0002443 174 0.031
proteasomal protein catabolic process GO:0010498 98 0.031
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.031
positive regulation of protein transport GO:0051222 93 0.031
urogenital system development GO:0001655 261 0.030
regulation of cell motility GO:2000145 236 0.030
positive regulation of protein phosphorylation GO:0001934 242 0.030
small molecule biosynthetic process GO:0044283 132 0.030
regulation of hormone levels GO:0010817 211 0.030
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.030
regulation of lipid storage GO:0010883 20 0.030
regulation of establishment of protein localization GO:0070201 181 0.030
neuromuscular process GO:0050905 99 0.030
lymphocyte proliferation GO:0046651 164 0.029
bone remodeling GO:0046849 53 0.029
sensory organ morphogenesis GO:0090596 242 0.029
response to peptide hormone GO:0043434 127 0.029
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.029
regulation of binding GO:0051098 111 0.029
response to bile acid GO:1903412 1 0.029
negative regulation of cellular amine metabolic process GO:0033239 1 0.029
protein autophosphorylation GO:0046777 61 0.029
morphogenesis of a branching structure GO:0001763 203 0.029
organelle assembly GO:0070925 177 0.028
cellular response to growth factor stimulus GO:0071363 197 0.028
camera type eye development GO:0043010 266 0.028
cell growth GO:0016049 130 0.028
negative regulation of apoptotic signaling pathway GO:2001234 104 0.028
cellular response to nutrient levels GO:0031669 64 0.028
Worm
lymphocyte differentiation GO:0030098 242 0.028
ceramide metabolic process GO:0006672 31 0.028
lateral inhibition GO:0046331 1 0.028
carbohydrate homeostasis GO:0033500 128 0.028
action potential GO:0001508 78 0.028
immune response regulating signaling pathway GO:0002764 125 0.028
positive regulation of cell motility GO:2000147 116 0.028
regulation of ion transport GO:0043269 215 0.028
development of primary sexual characteristics GO:0045137 143 0.028
kidney development GO:0001822 213 0.027
negative regulation of phosphorylation GO:0042326 166 0.027
cellular response to extracellular stimulus GO:0031668 81 0.027
Worm
methylation GO:0032259 134 0.027
renal system development GO:0072001 225 0.027
glucose metabolic process GO:0006006 92 0.027
adaptive immune response GO:0002250 155 0.027
erk1 and erk2 cascade GO:0070371 77 0.027
negative regulation of protein phosphorylation GO:0001933 126 0.027
regulation of lymphocyte proliferation GO:0050670 117 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.026
sphingolipid catabolic process GO:0030149 7 0.026
exocytosis GO:0006887 121 0.026
positive regulation of lipid metabolic process GO:0045834 40 0.026
rhythmic process GO:0048511 174 0.026
triglyceride metabolic process GO:0006641 51 0.026
Worm
organic acid catabolic process GO:0016054 51 0.026
response to molecule of bacterial origin GO:0002237 143 0.026
t cell proliferation GO:0042098 120 0.026
response to peptide GO:1901652 136 0.026
divalent metal ion transport GO:0070838 172 0.026
carboxylic acid catabolic process GO:0046395 51 0.026
oligosaccharide catabolic process GO:0009313 2 0.026
cellular response to peptide hormone stimulus GO:0071375 92 0.026
cerebellum development GO:0021549 77 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
muscle cell differentiation GO:0042692 261 0.025
regulation of ion homeostasis GO:2000021 64 0.025
alpha beta t cell activation GO:0046631 91 0.025
energy derivation by oxidation of organic compounds GO:0015980 77 0.025
nucleocytoplasmic transport GO:0006913 139 0.025
plasma membrane organization GO:0007009 90 0.025
protein kinase b signaling GO:0043491 74 0.025
glutamate metabolic process GO:0006536 9 0.025
steroid metabolic process GO:0008202 119 0.025
organ regeneration GO:0031100 2 0.025
regulation of neuron differentiation GO:0045664 281 0.025
nuclear transport GO:0051169 139 0.025
regulation of erk1 and erk2 cascade GO:0070372 71 0.025
photoreceptor cell development GO:0042461 40 0.024
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.024
heart morphogenesis GO:0003007 178 0.024
negative regulation of cell growth GO:0030308 44 0.024
axonogenesis GO:0007409 274 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
generation of precursor metabolites and energy GO:0006091 103 0.024
body fluid secretion GO:0007589 53 0.024
negative regulation of mapk cascade GO:0043409 65 0.024
cyclic purine nucleotide metabolic process GO:0052652 43 0.024
negative regulation of dna replication GO:0008156 4 0.024
multi multicellular organism process GO:0044706 109 0.024
neuron migration GO:0001764 122 0.024
regulation of fatty acid oxidation GO:0046320 10 0.024
negative regulation of map kinase activity GO:0043407 34 0.024
response to thyroid hormone GO:0097066 2 0.024
cell type specific apoptotic process GO:0097285 268 0.024
adult locomotory behavior GO:0008344 91 0.024
regulation of lymphocyte mediated immunity GO:0002706 84 0.024
hair cycle GO:0042633 90 0.024
response to low density lipoprotein particle GO:0055098 2 0.024
central nervous system neuron differentiation GO:0021953 162 0.023
anion transmembrane transport GO:0098656 71 0.023
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.023
regulation of camp biosynthetic process GO:0030817 25 0.023
cellular amide metabolic process GO:0043603 58 0.023
neutral lipid metabolic process GO:0006638 57 0.023
Worm
lymphocyte activation involved in immune response GO:0002285 93 0.023
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.023
regulation of proteolysis GO:0030162 164 0.023
positive regulation of map kinase activity GO:0043406 84 0.023
regulation of cellular component size GO:0032535 121 0.023
cellular response to molecule of bacterial origin GO:0071219 83 0.023
response to lipopolysaccharide GO:0032496 128 0.023
chemotaxis GO:0006935 247 0.023
germ cell development GO:0007281 185 0.023
regulation of tube size GO:0035150 57 0.023
epithelial cell morphogenesis GO:0003382 41 0.023
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.023
positive regulation of cell death GO:0010942 224 0.023
sterol metabolic process GO:0016125 58 0.023
protein processing GO:0016485 163 0.023
bmp signaling pathway GO:0030509 93 0.023
glycerolipid biosynthetic process GO:0045017 50 0.022
sphingolipid metabolic process GO:0006665 45 0.022
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.022
fatty acid oxidation GO:0019395 28 0.022
eye photoreceptor cell development GO:0042462 31 0.022
amino acid transmembrane transport GO:0003333 37 0.022
cellular response to prostaglandin e stimulus GO:0071380 1 0.022
cytoplasmic transport GO:0016482 234 0.022
regulation of multi organism process GO:0043900 111 0.022
tissue migration GO:0090130 68 0.022
hematopoietic progenitor cell differentiation GO:0002244 143 0.022
digestive system development GO:0055123 200 0.022
response to acid chemical GO:0001101 111 0.022
erythrocyte differentiation GO:0030218 88 0.022
positive regulation of secretion GO:0051047 130 0.022
membrane organization GO:0061024 245 0.022
apoptotic process involved in mammary gland involution GO:0060057 4 0.022
positive regulation of macroautophagy GO:0016239 3 0.022
Worm
limb morphogenesis GO:0035108 149 0.022
positive regulation of secretion by cell GO:1903532 114 0.022
intracellular protein transport GO:0006886 204 0.022
regulation of neuron projection development GO:0010975 169 0.022
regulation of protein kinase b signaling GO:0051896 56 0.022
acute inflammatory response GO:0002526 41 0.022
ammonia assimilation cycle GO:0019676 2 0.021
regulation of myeloid cell differentiation GO:0045637 96 0.021
molting cycle GO:0042303 90 0.021
protein localization to nucleus GO:0034504 121 0.021
hindbrain morphogenesis GO:0021575 46 0.021
regulation of osteoclast differentiation GO:0045670 36 0.021
biomineral tissue development GO:0031214 64 0.021
cellular response to acid chemical GO:0071229 68 0.021
positive regulation of camp mediated signaling GO:0043950 3 0.021
cell division GO:0051301 120 0.021
stress activated protein kinase signaling cascade GO:0031098 81 0.021
fatty acid transmembrane transport GO:1902001 1 0.021
regulation of receptor activity GO:0010469 41 0.021
response to steroid hormone GO:0048545 56 0.021
platelet aggregation GO:0070527 20 0.021
learning or memory GO:0007611 148 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.020
regulation of cellular protein catabolic process GO:1903362 61 0.020
regulation of phagocytosis GO:0050764 33 0.020
development of primary female sexual characteristics GO:0046545 73 0.020
cyclic nucleotide metabolic process GO:0009187 59 0.020
ribonucleoside monophosphate metabolic process GO:0009161 80 0.020
respiratory tube development GO:0030323 167 0.020
regulation of cell cycle GO:0051726 281 0.020
positive regulation of intracellular transport GO:0032388 70 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.020
negative regulation of wnt signaling pathway GO:0030178 73 0.020
response to insulin GO:0032868 100 0.020
acylglycerol metabolic process GO:0006639 55 0.020
Worm
actin filament organization GO:0007015 113 0.020
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.020
mechanoreceptor differentiation GO:0042490 67 0.020
metencephalon development GO:0022037 89 0.020
sterol transport GO:0015918 38 0.020
calcium ion transport GO:0006816 159 0.020
modification dependent macromolecule catabolic process GO:0043632 133 0.020
camp biosynthetic process GO:0006171 31 0.020
response to vitamin a GO:0033189 1 0.020
cellular response to insulin stimulus GO:0032869 78 0.020
cellular response to lipopolysaccharide GO:0071222 77 0.020
osteoclast differentiation GO:0030316 62 0.020
inner ear receptor cell differentiation GO:0060113 61 0.019
keratinocyte proliferation GO:0043616 21 0.019
myeloid leukocyte activation GO:0002274 83 0.019
second messenger mediated signaling GO:0019932 73 0.019
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.019

Lipa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.523
inherited metabolic disorder DOID:655 0 0.348
lysosomal storage disease DOID:3211 0 0.061
disease of anatomical entity DOID:7 0 0.051
integumentary system disease DOID:16 0 0.051
sensory system disease DOID:0050155 0 0.049
nervous system disease DOID:863 0 0.049
eye and adnexa disease DOID:1492 0 0.043
eye disease DOID:5614 0 0.043
retinal disease DOID:5679 0 0.030
central nervous system disease DOID:331 0 0.026
acquired metabolic disease DOID:0060158 0 0.024
metal metabolism disorder DOID:896 0 0.021
retinal degeneration DOID:8466 0 0.020
lipid storage disease DOID:9455 0 0.020
sphingolipidosis DOID:1927 0 0.020