Mus musculus

91 known processes

Ttn

titin

(Aliases: AF006999,L56,mdm,D330041I19Rik,D830007G01Rik,2310057K23Rik,shru,2310036G12Rik,AV006427,2310074I15Rik,1100001C23Rik)

Ttn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component assembly involved in morphogenesis GO:0010927 139 1.000
actin cytoskeleton organization GO:0030036 220 0.999
actomyosin structure organization GO:0031032 56 0.999
myofibril assembly GO:0030239 34 0.999
organelle assembly GO:0070925 177 0.995
muscle cell development GO:0055001 133 0.994
cardiac muscle tissue development GO:0048738 130 0.947
sodium ion import GO:0097369 1 0.947
cardiac muscle cell development GO:0055013 39 0.944
muscle tissue development GO:0060537 308 0.938
striated muscle cell development GO:0055002 125 0.904
striated muscle tissue development GO:0014706 293 0.895
calcium ion transport into cytosol GO:0060402 48 0.886
muscle fiber development GO:0048747 76 0.878
response to glycoside GO:1903416 2 0.864
muscle system process GO:0003012 141 0.832
muscle contraction GO:0006936 101 0.824
cardiac muscle tissue morphogenesis GO:0055008 44 0.813
sarcomere organization GO:0045214 24 0.804
myosin filament organization GO:0031033 3 0.783
regulation of ion transmembrane transport GO:0034765 119 0.777
inorganic ion transmembrane transport GO:0098660 234 0.774
regulation of ion transmembrane transporter activity GO:0032412 54 0.764
ion transmembrane transport GO:0034220 361 0.724
myotube differentiation GO:0014902 105 0.707
cellular metal ion homeostasis GO:0006875 151 0.699
skeletal muscle organ development GO:0060538 163 0.664
sequestering of calcium ion GO:0051208 18 0.663
cardiocyte differentiation GO:0035051 87 0.659
striated muscle contraction GO:0006941 45 0.639
sodium ion export GO:0071436 2 0.636
muscle tissue morphogenesis GO:0060415 53 0.615
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 12 0.581
regulation of skeletal muscle adaptation GO:0014733 12 0.564
regulation of skeletal muscle contraction GO:0014819 3 0.538
regulation of ion transport GO:0043269 215 0.525
muscle cell differentiation GO:0042692 261 0.524
blood circulation GO:0008015 195 0.505
cellular calcium ion homeostasis GO:0006874 119 0.486
calcium ion transmembrane transport GO:0070588 85 0.484
glycosyl compound metabolic process GO:1901657 246 0.464
regulation of membrane potential GO:0042391 192 0.450
cytosolic calcium ion transport GO:0060401 48 0.420
dna metabolic process GO:0006259 303 0.390
muscle adaptation GO:0043500 39 0.388
regulation of atp metabolic process GO:1903578 17 0.386
regulation of transmembrane transport GO:0034762 128 0.384
regulation of ion homeostasis GO:2000021 64 0.377
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 9 0.374
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.372
skeletal myofibril assembly GO:0014866 4 0.371
cellular response to organonitrogen compound GO:0071417 145 0.370
cardiac muscle contraction GO:0060048 32 0.358
inorganic cation transmembrane transport GO:0098662 207 0.356
regulation of potassium ion transmembrane transporter activity GO:1901016 7 0.354
regulation of muscle adaptation GO:0043502 31 0.342
cation transport GO:0006812 399 0.330
cellular divalent inorganic cation homeostasis GO:0072503 127 0.321
regulation of metal ion transport GO:0010959 106 0.311
divalent inorganic cation transport GO:0072511 178 0.308
regulation of membrane repolarization GO:0060306 7 0.308
regulation of cellular ketone metabolic process GO:0010565 66 0.293
endoplasmic reticulum to cytosol transport GO:1903513 12 0.291
cellular response to lipid GO:0071396 145 0.289
response to organonitrogen compound GO:0010243 246 0.289
cellular response to organic cyclic compound GO:0071407 87 0.281
cation transmembrane transport GO:0098655 266 0.279
release of sequestered calcium ion into cytosol GO:0051209 42 0.267
sequestering of metal ion GO:0051238 19 0.259
regulation of transporter activity GO:0032409 57 0.248
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.242
cation homeostasis GO:0055080 212 0.235
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.232
purine ribonucleoside metabolic process GO:0046128 241 0.232
cellular chemical homeostasis GO:0055082 215 0.228
regulation of the force of heart contraction GO:0002026 17 0.226
atp metabolic process GO:0046034 75 0.225
positive regulation of ion transport GO:0043270 65 0.223
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 7 0.220
actin filament organization GO:0007015 113 0.211
cellular protein complex assembly GO:0043623 116 0.211
myosin filament assembly GO:0031034 2 0.209
skeletal muscle fiber development GO:0048741 58 0.207
negative regulation of cellular amine metabolic process GO:0033239 1 0.199
potassium ion transmembrane transport GO:0071805 43 0.198
regulation of muscle system process GO:0090257 80 0.196
response to purine containing compound GO:0014074 28 0.195
calcium ion transport GO:0006816 159 0.193
regulation of atp biosynthetic process GO:2001169 3 0.192
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 12 0.187
heart morphogenesis GO:0003007 178 0.163
cytosolic calcium ion homeostasis GO:0051480 70 0.160
regulation of purine nucleotide metabolic process GO:1900542 169 0.155
cardiac chamber development GO:0003205 108 0.154
regulation of cation channel activity GO:2001257 22 0.154
relaxation of muscle GO:0090075 18 0.152
cytoplasmic transport GO:0016482 234 0.150
regulation of heart contraction GO:0008016 77 0.150
myotube cell development GO:0014904 60 0.146
regulation of system process GO:0044057 200 0.140
response to activity GO:0014823 13 0.139
regulation of cellular catabolic process GO:0031329 242 0.137
regulation of cellular amine metabolic process GO:0033238 20 0.137
regulation of skeletal muscle fiber development GO:0048742 36 0.136
amine metabolic process GO:0009308 45 0.136
positive regulation of cellular respiration GO:1901857 3 0.135
negative regulation of molecular function GO:0044092 258 0.135
regulation of myotube differentiation GO:0010830 62 0.134
purine containing compound metabolic process GO:0072521 311 0.132
positive regulation of ion transmembrane transport GO:0034767 24 0.126
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.126
regulation of intracellular transport GO:0032386 159 0.125
regulation of blood circulation GO:1903522 93 0.123
regulation of cardiac muscle contraction GO:0055117 21 0.123
oxidation reduction process GO:0055114 342 0.121
purine nucleotide metabolic process GO:0006163 302 0.117
response to organic cyclic compound GO:0014070 198 0.116
regulation of potassium ion transmembrane transport GO:1901379 11 0.115
purine nucleoside metabolic process GO:0042278 241 0.114
purine nucleoside monophosphate catabolic process GO:0009128 58 0.114
transition between fast and slow fiber GO:0014883 9 0.112
positive regulation of transmembrane transport GO:0034764 29 0.111
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 10 0.110
divalent inorganic cation homeostasis GO:0072507 138 0.108
ribose phosphate metabolic process GO:0019693 291 0.105
nucleoside monophosphate metabolic process GO:0009123 85 0.105
cellular amine metabolic process GO:0044106 44 0.104
neuron apoptotic process GO:0051402 142 0.103
response to oxidative stress GO:0006979 123 0.101
positive regulation of atp biosynthetic process GO:2001171 2 0.098
ribonucleoside catabolic process GO:0042454 206 0.097
cellular potassium ion transport GO:0071804 43 0.095
regulation of atp catabolic process GO:1903289 9 0.095
divalent metal ion transport GO:0070838 172 0.095
dna biosynthetic process GO:0071897 22 0.095
regulation of organelle organization GO:0033043 289 0.095
cellular homeostasis GO:0019725 240 0.094
nucleoside monophosphate catabolic process GO:0009125 59 0.094
regulation of striated muscle contraction GO:0006942 25 0.093
fatty acid metabolic process GO:0006631 121 0.093
membrane repolarization GO:0086009 7 0.092
negative regulation of homeostatic process GO:0032845 71 0.092
ribonucleoside triphosphate catabolic process GO:0009203 199 0.091
nucleoside phosphate metabolic process GO:0006753 338 0.091
regulation of hydrolase activity GO:0051336 246 0.090
regulation of calcium ion transport GO:0051924 69 0.088
maintenance of location GO:0051235 89 0.088
ribonucleoside metabolic process GO:0009119 245 0.088
regulation of neuron differentiation GO:0045664 281 0.086
regulation of mitochondrion organization GO:0010821 27 0.084
regulation of homeostatic process GO:0032844 182 0.082
purine nucleoside monophosphate metabolic process GO:0009126 81 0.081
monocarboxylic acid metabolic process GO:0032787 191 0.080
myeloid cell differentiation GO:0030099 233 0.080
nucleoside triphosphate metabolic process GO:0009141 230 0.079
purine nucleotide catabolic process GO:0006195 211 0.078
positive regulation of potassium ion transmembrane transporter activity GO:1901018 1 0.078
skeletal muscle myosin thick filament assembly GO:0030241 1 0.076
sodium ion transmembrane transport GO:0035725 49 0.076
organic cyclic compound catabolic process GO:1901361 295 0.076
cellular ion homeostasis GO:0006873 165 0.075
positive regulation of transporter activity GO:0032411 17 0.075
cellular ketone metabolic process GO:0042180 84 0.074
cell junction organization GO:0034330 77 0.074
purine containing compound catabolic process GO:0072523 213 0.073
apoptotic signaling pathway GO:0097190 306 0.073
heart process GO:0003015 94 0.073
heart contraction GO:0060047 93 0.070
regulation of sarcomere organization GO:0060297 4 0.070
cellular response to cytokine stimulus GO:0071345 189 0.070
organonitrogen compound biosynthetic process GO:1901566 192 0.070
purine nucleoside triphosphate metabolic process GO:0009144 226 0.069
mitochondrion organization GO:0007005 134 0.069
organonitrogen compound catabolic process GO:1901565 264 0.067
skeletal muscle adaptation GO:0043501 16 0.066
positive regulation of potassium ion transmembrane transport GO:1901381 3 0.065
purine ribonucleoside catabolic process GO:0046130 205 0.064
cardiac muscle cell contraction GO:0086003 7 0.064
cardiac myofibril assembly GO:0055003 12 0.064
regulation of cytoplasmic transport GO:1903649 112 0.063
cellular respiration GO:0045333 38 0.063
circulatory system process GO:0003013 197 0.062
response to catecholamine GO:0071869 4 0.062
regulation of leukocyte differentiation GO:1902105 159 0.062
nucleobase containing small molecule metabolic process GO:0055086 352 0.061
heterocycle catabolic process GO:0046700 280 0.061
regulation of striated muscle cell differentiation GO:0051153 81 0.060
striated muscle adaptation GO:0014888 26 0.060
ribonucleoside triphosphate metabolic process GO:0009199 220 0.060
nucleotide metabolic process GO:0009117 332 0.059
negative regulation of phosphate metabolic process GO:0045936 184 0.059
leukocyte differentiation GO:0002521 342 0.059
regulation of ryanodine sensitive calcium release channel activity GO:0060314 10 0.059
cardiac septum development GO:0003279 59 0.059
skeletal muscle cell differentiation GO:0035914 66 0.059
multicellular organismal aging GO:0010259 24 0.057
negative regulation of cell proliferation GO:0008285 296 0.056
response to camp GO:0051591 14 0.055
lipid modification GO:0030258 65 0.055
metal ion homeostasis GO:0055065 189 0.055
aromatic compound catabolic process GO:0019439 286 0.054
positive regulation of alkaline phosphatase activity GO:0010694 3 0.053
cellular lipid metabolic process GO:0044255 323 0.053
ribonucleotide metabolic process GO:0009259 291 0.053
response to inorganic substance GO:0010035 96 0.053
regulation of calcium ion transport into cytosol GO:0010522 31 0.052
response to oxygen levels GO:0070482 62 0.052
generation of precursor metabolites and energy GO:0006091 103 0.052
striated muscle cell proliferation GO:0014855 39 0.052
galactose metabolic process GO:0006012 4 0.052
transmembrane transport GO:0055085 412 0.052
purine ribonucleotide metabolic process GO:0009150 290 0.051
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.051
cardiac ventricle development GO:0003231 83 0.050
positive regulation of potassium ion transport GO:0043268 3 0.049
striated muscle myosin thick filament assembly GO:0071688 1 0.049
relaxation of smooth muscle GO:0044557 8 0.049
skeletal muscle thin filament assembly GO:0030240 2 0.048
cellular response to dna damage stimulus GO:0006974 207 0.048
muscle filament sliding GO:0030049 1 0.048
positive regulation of nucleotide metabolic process GO:0045981 114 0.048
reactive oxygen species metabolic process GO:0072593 84 0.048
peptidyl amino acid modification GO:0018193 336 0.047
positive regulation of hydrolase activity GO:0051345 148 0.046
regulation of secretion by cell GO:1903530 249 0.045
positive regulation of organelle organization GO:0010638 128 0.045
protein catabolic process GO:0030163 221 0.045
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.043
regulation of receptor activity GO:0010469 41 0.043
regulation of cytoskeleton organization GO:0051493 122 0.042
calcium ion homeostasis GO:0055074 127 0.041
cellular response to biotic stimulus GO:0071216 92 0.040
anatomical structure homeostasis GO:0060249 145 0.040
ras protein signal transduction GO:0007265 77 0.039
regulation of actin filament based process GO:0032970 99 0.039
cellular protein catabolic process GO:0044257 155 0.039
negative regulation of protein modification process GO:0031400 163 0.039
regulation of heart rate GO:0002027 36 0.038
ribonucleoside monophosphate catabolic process GO:0009158 57 0.038
nucleoside metabolic process GO:0009116 246 0.038
actin filament based movement GO:0030048 23 0.038
establishment of blood nerve barrier GO:0008065 3 0.037
carbohydrate metabolic process GO:0005975 230 0.037
sa node cell action potential GO:0086015 4 0.037
intrinsic apoptotic signaling pathway GO:0097193 132 0.036
i kappab kinase nf kappab signaling GO:0007249 85 0.036
protein localization to organelle GO:0033365 185 0.036
cellular response to molecule of bacterial origin GO:0071219 83 0.036
regulation of anatomical structure size GO:0090066 178 0.036
cellular response to steroid hormone stimulus GO:0071383 33 0.035
response to alkaloid GO:0043279 34 0.035
carbohydrate derivative catabolic process GO:1901136 231 0.035
potassium ion transport GO:0006813 52 0.035
cellular response to oxidative stress GO:0034599 76 0.035
dephosphorylation GO:0016311 129 0.035
negative regulation of neuron death GO:1901215 98 0.035
regulation of heart growth GO:0060420 31 0.034
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
cardiac cell development GO:0055006 41 0.034
organophosphate biosynthetic process GO:0090407 122 0.034
actin mediated cell contraction GO:0070252 15 0.034
ventricular cardiac muscle cell action potential GO:0086005 4 0.033
regulation of protein localization GO:0032880 231 0.033
regulation of feeding behavior GO:0060259 3 0.032
response to organophosphorus GO:0046683 22 0.032
rna dependent dna replication GO:0006278 3 0.032
regulation of muscle contraction GO:0006937 49 0.032
microtubule based process GO:0007017 236 0.031
calcium ion import GO:0070509 14 0.031
embryonic heart tube development GO:0035050 65 0.030
regulation of cell projection organization GO:0031344 206 0.030
cellular modified amino acid metabolic process GO:0006575 63 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.030
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.029
microtubule cytoskeleton organization GO:0000226 157 0.029
regulation of protein stability GO:0031647 52 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.029
hematopoietic stem cell differentiation GO:0060218 8 0.028
positive regulation of phosphatase activity GO:0010922 4 0.028
cellular response to lipopolysaccharide GO:0071222 77 0.028
response to hypoxia GO:0001666 58 0.028
positive regulation of mitochondrion organization GO:0010822 17 0.028
cellular response to acid chemical GO:0071229 68 0.028
cellular amino acid metabolic process GO:0006520 103 0.028
cellular response to tumor necrosis factor GO:0071356 21 0.027
necrotic cell death GO:0070265 30 0.027
wound healing GO:0042060 157 0.027
energy homeostasis GO:0097009 15 0.027
positive regulation of neuron projection development GO:0010976 79 0.027
regulation of secretion GO:0051046 274 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
skeletal system morphogenesis GO:0048705 203 0.027
cardiac muscle fiber development GO:0048739 4 0.026
stem cell differentiation GO:0048863 268 0.026
organophosphate catabolic process GO:0046434 232 0.026
positive regulation of homeostatic process GO:0032846 64 0.026
av node cell to bundle of his cell communication GO:0086067 2 0.026
response to muscle stretch GO:0035994 1 0.026
response to temperature stimulus GO:0009266 55 0.026
negative regulation of smooth muscle cell migration GO:0014912 2 0.026
regulation of cellular respiration GO:0043457 10 0.025
actin polymerization or depolymerization GO:0008154 54 0.025
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.025
actin myosin filament sliding GO:0033275 1 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
regulation of muscle tissue development GO:1901861 97 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
regulation of nucleotide metabolic process GO:0006140 169 0.024
nucleoside biosynthetic process GO:0009163 21 0.024
methylation GO:0032259 134 0.024
protein localization to nucleus GO:0034504 121 0.024
cellular response to caffeine GO:0071313 4 0.024
macromolecule catabolic process GO:0009057 281 0.024
response to starvation GO:0042594 65 0.024
protein modification by small protein conjugation GO:0032446 187 0.024
ribonucleoside monophosphate metabolic process GO:0009161 80 0.024
vasoconstriction GO:0042310 27 0.024
purine nucleoside biosynthetic process GO:0042451 19 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
microtubule based movement GO:0007018 84 0.023
rna processing GO:0006396 105 0.023
vascular smooth muscle contraction GO:0014829 5 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
regulation of protein secretion GO:0050708 82 0.023
cellular macromolecule catabolic process GO:0044265 206 0.023
positive regulation of atpase activity GO:0032781 3 0.023
purine ribonucleoside biosynthetic process GO:0046129 19 0.023
peptidyl serine modification GO:0018209 83 0.023
b cell mediated immunity GO:0019724 71 0.023
regulation of chromosome organization GO:0033044 83 0.023
ribonucleotide catabolic process GO:0009261 208 0.022
neuron death GO:0070997 154 0.022
smooth muscle contraction GO:0006939 44 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
protein targeting GO:0006605 143 0.022
negative regulation of cytosolic calcium ion concentration GO:0051481 2 0.022
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.022
canonical wnt signaling pathway GO:0060070 130 0.022
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.022
response to extracellular stimulus GO:0009991 127 0.022
regeneration GO:0031099 38 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
syncytium formation GO:0006949 43 0.021
regulation of protein transport GO:0051223 163 0.021
atp catabolic process GO:0006200 55 0.021
cardiac ventricle morphogenesis GO:0003208 50 0.021
nucleotide catabolic process GO:0009166 217 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
cellular response to thyroid hormone stimulus GO:0097067 1 0.021
positive regulation of cation channel activity GO:2001259 8 0.021
regulation of cytokine production GO:0001817 266 0.021
response to thyroid hormone GO:0097066 2 0.021
regulation of transferase activity GO:0051338 263 0.021
regulation of voltage gated calcium channel activity GO:1901385 4 0.021
energy derivation by oxidation of organic compounds GO:0015980 77 0.020
multi organism behavior GO:0051705 62 0.020
positive regulation of protein transport GO:0051222 93 0.020
regulation of myeloid cell differentiation GO:0045637 96 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.020
protein alkylation GO:0008213 81 0.020
feeding behavior GO:0007631 62 0.020
regulation of organ growth GO:0046620 61 0.020
muscle cell proliferation GO:0033002 52 0.019
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.019
regulation of cellular amino acid metabolic process GO:0006521 5 0.019
positive regulation of sodium ion transmembrane transport GO:1902307 4 0.019
positive regulation of glial cell proliferation GO:0060252 4 0.019
regulation of circadian rhythm GO:0042752 58 0.019
negative regulation of glycolytic process GO:0045820 4 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
protein secretion GO:0009306 111 0.019
body morphogenesis GO:0010171 45 0.019
regulation of protein binding GO:0043393 60 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
regulation of glutamate receptor signaling pathway GO:1900449 16 0.019
regulation of myoblast differentiation GO:0045661 29 0.019
response to amino acid GO:0043200 37 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
sulfur compound metabolic process GO:0006790 100 0.018
ribonucleoside monophosphate biosynthetic process GO:0009156 9 0.018
multicellular organismal signaling GO:0035637 91 0.018
acetylcholine transport GO:0015870 2 0.018
regulation of dephosphorylation GO:0035303 18 0.018
positive regulation of cell development GO:0010720 237 0.018
cellular response to amino acid stimulus GO:0071230 29 0.018
myoblast differentiation GO:0045445 52 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
positive regulation of lipid storage GO:0010884 10 0.018
embryonic placenta development GO:0001892 98 0.018
macromolecule methylation GO:0043414 120 0.018
regulation of skeletal muscle contraction by calcium ion signaling GO:0014722 3 0.018
glycoprotein metabolic process GO:0009100 116 0.018
negative regulation of protein phosphorylation GO:0001933 126 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
telomere maintenance GO:0000723 19 0.017
regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902253 13 0.017
positive regulation of cell projection organization GO:0031346 95 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
positive regulation of fatty acid oxidation GO:0046321 4 0.017
peripheral nervous system neuron axonogenesis GO:0048936 3 0.017
regulation of neuron projection development GO:0010975 169 0.017
positive regulation of secretion GO:0051047 130 0.017
regulation of blood pressure GO:0008217 93 0.017
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.017
glycolytic process GO:0006096 20 0.017
organelle localization GO:0051640 179 0.017
protein depolymerization GO:0051261 34 0.017
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.017
positive regulation of cytoplasmic transport GO:1903651 40 0.017
cytokine production GO:0001816 319 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
signal transduction by p53 class mediator GO:0072331 51 0.017
carbohydrate catabolic process GO:0016052 32 0.017
positive regulation of mitochondrial calcium ion concentration GO:0051561 3 0.017
cardiac muscle cell differentiation GO:0055007 69 0.017
positive regulation of nucleoside metabolic process GO:0045979 91 0.017
apoptotic mitochondrial changes GO:0008637 48 0.017
cellular response to inorganic substance GO:0071241 37 0.017
cardiac conduction GO:0061337 17 0.016
mitochondrial rna metabolic process GO:0000959 7 0.016
chromatin organization GO:0006325 206 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
negative regulation of protein complex disassembly GO:0043242 22 0.016
regulation of kinase activity GO:0043549 249 0.016
regulation of alkaline phosphatase activity GO:0010692 6 0.016
protein import into nucleus GO:0006606 95 0.016
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.016
mitotic cell cycle GO:0000278 195 0.016
regulation of wound healing GO:0061041 40 0.016
leukocyte activation involved in immune response GO:0002366 126 0.016
modification dependent protein catabolic process GO:0019941 133 0.016
positive regulation of striated muscle contraction GO:0045989 3 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
positive regulation of vasoconstriction GO:0045907 4 0.016
carbohydrate transport GO:0008643 62 0.016
positive regulation of calcium ion transport GO:0051928 27 0.016
germ cell development GO:0007281 185 0.016
regulation of calcium ion transmembrane transport GO:1903169 20 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
determination of adult lifespan GO:0008340 11 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
ventricular septum development GO:0003281 42 0.015
cell communication by electrical coupling involved in cardiac conduction GO:0086064 2 0.015
cell adhesion GO:0007155 329 0.015
innate immune response GO:0045087 157 0.015
telomere maintenance via telomerase GO:0007004 1 0.015
nucleoside phosphate biosynthetic process GO:1901293 79 0.015
compound eye development GO:0048749 1 0.015
response to tumor necrosis factor GO:0034612 26 0.015
multi multicellular organism process GO:0044706 109 0.015
vagus nerve development GO:0021564 3 0.015
mitotic cytokinesis GO:0000281 4 0.015
actin filament polymerization GO:0030041 44 0.015
positive regulation of bone remodeling GO:0046852 13 0.015
regulation of adaptive immune response GO:0002819 90 0.015
spermatogenesis GO:0007283 284 0.015
cellular response to decreased oxygen levels GO:0036294 18 0.014
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
positive regulation of immune effector process GO:0002699 107 0.014
negative regulation of protein depolymerization GO:1901880 21 0.014
cardiac chamber morphogenesis GO:0003206 93 0.014
positive regulation of necrotic cell death GO:0010940 1 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
response to lipopolysaccharide GO:0032496 128 0.014
response to nutrient levels GO:0031667 109 0.014
organ growth GO:0035265 117 0.014
response to drug GO:0042493 75 0.014
ribonucleoside biosynthetic process GO:0042455 21 0.014
cellular response to salt stress GO:0071472 1 0.014
tissue regeneration GO:0042246 22 0.014
olfactory learning GO:0008355 2 0.014
membrane depolarization during sa node cell action potential GO:0086046 2 0.014
regulation of lymphocyte mediated immunity GO:0002706 84 0.014

Ttn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.992
disease of anatomical entity DOID:7 0 0.992
musculoskeletal system disease DOID:17 0 0.992
muscle tissue disease DOID:66 0 0.992
myopathy DOID:423 0 0.850
heart disease DOID:114 0 0.850
cardiomyopathy DOID:0050700 0 0.850
cardiovascular system disease DOID:1287 0 0.850
muscular dystrophy DOID:9884 0 0.717
dilated cardiomyopathy DOID:12930 0 0.255
intrinsic cardiomyopathy DOID:0060036 0 0.255
limb girdle muscular dystrophy DOID:11724 0 0.211
nervous system disease DOID:863 0 0.041
neuropathy DOID:870 0 0.027
neuromuscular disease DOID:440 0 0.024
disease of metabolism DOID:0014667 0 0.015
hypertrophic cardiomyopathy DOID:11984 0 0.014