Mus musculus

27 known processes

Smurf1

SMAD specific E3 ubiquitin protein ligase 1

(Aliases: 4930431E10Rik,mKIAA1625)

Smurf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pigment accumulation GO:0043476 1 0.999
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.811
negative regulation of cellular amine metabolic process GO:0033239 1 0.601
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.542
negative regulation of phosphorylation GO:0042326 166 0.409
Mouse
negative regulation of pathway restricted smad protein phosphorylation GO:0060394 1 0.386
regulation of cellular amine metabolic process GO:0033238 20 0.381
negative regulation of osteoblast proliferation GO:0033689 4 0.349
negative regulation of protein phosphorylation GO:0001933 126 0.304
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.297
negative regulation of synapse assembly GO:0051964 3 0.296
negative regulation of phosphorus metabolic process GO:0010563 184 0.289
Mouse
negative regulation of defense response GO:0031348 77 0.286
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.257
cellular macromolecule catabolic process GO:0044265 206 0.254
Human Mouse Fly
cardiac muscle contraction GO:0060048 32 0.239
brainstem development GO:0003360 3 0.237
negative regulation of protein modification process GO:0031400 163 0.232
regulation of cell proliferation involved in heart valve morphogenesis GO:0003250 1 0.224
regulation of defense response GO:0031347 233 0.195
Mouse
peptidyl serine modification GO:0018209 83 0.194
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.193
regulation of smad protein import into nucleus GO:0060390 3 0.183
striated muscle contraction GO:0006941 45 0.175
ubiquitin dependent protein catabolic process GO:0006511 129 0.173
Human Mouse Fly
kidney mesenchyme morphogenesis GO:0072131 4 0.168
regulation of response to wounding GO:1903034 189 0.167
regulation of transferase activity GO:0051338 263 0.160
negative regulation of peptidyl threonine phosphorylation GO:0010801 6 0.159
macromolecule catabolic process GO:0009057 281 0.158
Human Mouse Fly
cellular amine metabolic process GO:0044106 44 0.158
cellular response to organic cyclic compound GO:0071407 87 0.156
cell proliferation involved in heart valve development GO:2000793 2 0.156
cellular protein complex assembly GO:0043623 116 0.156
regulation of cellular amino acid metabolic process GO:0006521 5 0.149
regulation of mapk cascade GO:0043408 248 0.143
Mouse
cellular ketone metabolic process GO:0042180 84 0.143
stress activated mapk cascade GO:0051403 80 0.142
Mouse
metanephric mesenchyme morphogenesis GO:0072133 4 0.139
positive regulation of protein modification process GO:0031401 299 0.139
cell adhesion GO:0007155 329 0.137
negative regulation of cellular protein metabolic process GO:0032269 247 0.136
regulation of inflammatory response GO:0050727 147 0.136
regulation of muscle contraction GO:0006937 49 0.135
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.134
Human Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.134
regulation of peptidyl serine phosphorylation GO:0033135 39 0.130
nephrogenic mesenchyme development GO:0072076 3 0.128
protein modification by small protein conjugation GO:0032446 187 0.126
social behavior GO:0035176 21 0.125
amine metabolic process GO:0009308 45 0.122
modification dependent protein catabolic process GO:0019941 133 0.120
Human Mouse Fly
proteasomal protein catabolic process GO:0010498 98 0.119
Human Mouse
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.119
Human
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.117
Human Mouse Fly
regulation of stress activated mapk cascade GO:0032872 69 0.110
Mouse
t cell activation GO:0042110 289 0.110
Mouse
mapk cascade GO:0000165 281 0.109
Mouse
heterocycle catabolic process GO:0046700 280 0.107
modification dependent macromolecule catabolic process GO:0043632 133 0.107
Human Mouse Fly
cellular amino acid metabolic process GO:0006520 103 0.106
negative regulation of inflammatory response GO:0050728 61 0.106
regulation of intracellular transport GO:0032386 159 0.101
positive regulation of smad protein import into nucleus GO:0060391 2 0.099
peptidyl serine phosphorylation GO:0018105 74 0.098
positive regulation of cellular catabolic process GO:0031331 148 0.096
smad protein complex assembly GO:0007183 1 0.095
cell proliferation involved in heart valve morphogenesis GO:0003249 1 0.094
stress activated protein kinase signaling cascade GO:0031098 81 0.094
Mouse
heart contraction GO:0060047 93 0.093
positive regulation of intracellular transport GO:0032388 70 0.092
response to growth factor GO:0070848 198 0.092
Human Mouse Fly
camera type eye development GO:0043010 266 0.090
negative regulation of molecular function GO:0044092 258 0.090
Mouse
germ cell development GO:0007281 185 0.089
Fly
cellular protein catabolic process GO:0044257 155 0.089
Human Mouse Fly
endothelial cell activation GO:0042118 1 0.087
gland development GO:0048732 330 0.087
inflammatory response GO:0006954 244 0.087
intracellular protein transport GO:0006886 204 0.084
Human
positive regulation of transferase activity GO:0051347 167 0.084
regulation of cardiac muscle contraction GO:0055117 21 0.082
ras protein signal transduction GO:0007265 77 0.082
lens development in camera type eye GO:0002088 62 0.082
cardiac endothelial cell differentiation GO:0003348 4 0.081
aromatic compound catabolic process GO:0019439 286 0.081
negative regulation of phosphate metabolic process GO:0045936 184 0.079
Mouse
jnk cascade GO:0007254 72 0.079
Mouse
immune effector process GO:0002252 321 0.079
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.079
Human Fly
protein localization to organelle GO:0033365 185 0.079
nucleoside triphosphate catabolic process GO:0009143 205 0.077
endocardial cell differentiation GO:0060956 4 0.077
intraspecies interaction between organisms GO:0051703 21 0.077
protein catabolic process GO:0030163 221 0.076
Human Mouse Fly
pigmentation GO:0043473 71 0.076
muscle contraction GO:0006936 101 0.076
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.074
Human
positive regulation of protein catabolic process GO:0045732 60 0.074
Mouse
negative regulation of cellular component organization GO:0051129 194 0.073
peptidyl threonine modification GO:0018210 31 0.072
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.071
Human Fly
regulation of cytoplasmic transport GO:1903649 112 0.071
cellular response to growth factor stimulus GO:0071363 197 0.069
Human Mouse Fly
positive regulation of mapk cascade GO:0043410 170 0.069
response to organic cyclic compound GO:0014070 198 0.069
positive regulation of cellular amine metabolic process GO:0033240 5 0.068
nucleoside phosphate metabolic process GO:0006753 338 0.068
cellular nitrogen compound catabolic process GO:0044270 280 0.068
nitrogen compound transport GO:0071705 271 0.068
positive regulation of protein import into nucleus GO:0042307 26 0.067
nucleobase containing small molecule metabolic process GO:0055086 352 0.067
regulation of cellular component biogenesis GO:0044087 181 0.067
Mouse
homeostasis of number of cells GO:0048872 210 0.067
small gtpase mediated signal transduction GO:0007264 97 0.066
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.066
nuclear transport GO:0051169 139 0.065
Human
skeletal system development GO:0001501 356 0.065
leukocyte proliferation GO:0070661 172 0.064
Mouse
renal system development GO:0072001 225 0.064
regulation of lymphocyte activation GO:0051249 240 0.064
Mouse
establishment of protein localization to organelle GO:0072594 118 0.064
regulation of muscle system process GO:0090257 80 0.063
regulation of protein targeting GO:1903533 61 0.063
response to fluid shear stress GO:0034405 7 0.063
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.063
respiratory system development GO:0060541 190 0.062
positive regulation of protein phosphorylation GO:0001934 242 0.062
peptidyl threonine phosphorylation GO:0018107 31 0.062
rho protein signal transduction GO:0007266 32 0.061
heart morphogenesis GO:0003007 178 0.060
Mouse
regulation of blood circulation GO:1903522 93 0.059
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.059
Mouse
regulation of neuron differentiation GO:0045664 281 0.059
Mouse
regulation of heart contraction GO:0008016 77 0.058
protein polyubiquitination GO:0000209 33 0.058
Human Mouse
regulation of purine nucleotide catabolic process GO:0033121 122 0.058
negative regulation of cell proliferation GO:0008285 296 0.058
Mouse
regulation of nucleocytoplasmic transport GO:0046822 73 0.057
hepaticobiliary system development GO:0061008 67 0.057
regulation of kinase activity GO:0043549 249 0.057
negative regulation of response to wounding GO:1903035 77 0.056
membrane organization GO:0061024 245 0.055
neural tube development GO:0021915 160 0.055
regulation of protein localization GO:0032880 231 0.053
osteoblast fate commitment GO:0002051 4 0.053
respiratory tube development GO:0030323 167 0.053
positive regulation of kinase activity GO:0033674 155 0.053
protein import GO:0017038 101 0.052
bmp signaling pathway GO:0030509 93 0.052
Human Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.052
Human Fly
chemotaxis GO:0006935 247 0.052
positive regulation of intracellular protein transport GO:0090316 42 0.052
regulation of protein import into nucleus GO:0042306 52 0.052
regulation of intracellular protein transport GO:0033157 82 0.051
regulation of protein complex assembly GO:0043254 83 0.051
nucleotide metabolic process GO:0009117 332 0.051
muscle system process GO:0003012 141 0.051
dna metabolic process GO:0006259 303 0.051
purine containing compound catabolic process GO:0072523 213 0.051
single organism nuclear import GO:1902593 95 0.050
positive regulation of proteolysis GO:0045862 85 0.050
myeloid cell homeostasis GO:0002262 114 0.050
positive regulation of protein kinase activity GO:0045860 144 0.049
protein ubiquitination GO:0016567 171 0.049
peptide transport GO:0015833 133 0.049
protein import into nucleus GO:0006606 95 0.049
regulation of cellular response to growth factor stimulus GO:0090287 82 0.049
Human Mouse
regulation of cell adhesion GO:0030155 154 0.048
regulation of protein kinase activity GO:0045859 232 0.048
regulation of cell cycle GO:0051726 281 0.048
male gamete generation GO:0048232 285 0.048
cytoplasmic transport GO:0016482 234 0.048
Human
axonogenesis GO:0007409 274 0.048
negative regulation of growth GO:0045926 99 0.048
protein targeting GO:0006605 143 0.048
regulation of pathway restricted smad protein phosphorylation GO:0060393 6 0.048
digestive system development GO:0055123 200 0.047
Fly
regulation of protein transport GO:0051223 163 0.047
positive regulation of stress activated mapk cascade GO:0032874 48 0.047
regulation of hair cycle GO:0042634 11 0.047
regulation of wound healing GO:0061041 40 0.046
digestive tract development GO:0048565 190 0.046
Fly
organonitrogen compound catabolic process GO:1901565 264 0.046
glycosyl compound catabolic process GO:1901658 206 0.046
ribonucleoside metabolic process GO:0009119 245 0.045
embryonic organ morphogenesis GO:0048562 276 0.045
skeletal system morphogenesis GO:0048705 203 0.045
lymphocyte differentiation GO:0030098 242 0.045
cation transport GO:0006812 399 0.045
Mouse
spermatogenesis GO:0007283 284 0.045
regulation of peptidyl threonine phosphorylation GO:0010799 12 0.044
carbohydrate derivative catabolic process GO:1901136 231 0.044
amide transport GO:0042886 138 0.044
urogenital system development GO:0001655 261 0.044
embryonic skeletal system development GO:0048706 120 0.044
locomotory behavior GO:0007626 195 0.044
nucleocytoplasmic transport GO:0006913 139 0.043
Human
purine ribonucleoside metabolic process GO:0046128 241 0.043
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.043
regulation of system process GO:0044057 200 0.043
circulatory system process GO:0003013 197 0.042
Mouse
positive regulation of cell development GO:0010720 237 0.042
regionalization GO:0003002 337 0.042
positive regulation of protein localization to nucleus GO:1900182 30 0.042
actin cytoskeleton organization GO:0030036 220 0.042
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.042
Human Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.042
Human Fly
regulation of establishment of protein localization GO:0070201 181 0.042
regulation of cell migration GO:0030334 219 0.041
morphogenesis of embryonic epithelium GO:0016331 159 0.041
heart process GO:0003015 94 0.041
embryonic epithelial tube formation GO:0001838 130 0.041
bone development GO:0060348 120 0.041
positive regulation of cytoplasmic transport GO:1903651 40 0.041
neuron projection guidance GO:0097485 141 0.040
regulation of hydrolase activity GO:0051336 246 0.040
purine nucleoside triphosphate catabolic process GO:0009146 203 0.040
ossification GO:0001503 216 0.040
regulation of hormone levels GO:0010817 211 0.040
lung development GO:0030324 164 0.040
regulation of alpha beta t cell activation GO:0046634 53 0.040
Mouse
muscle tissue development GO:0060537 308 0.039
guanosine containing compound metabolic process GO:1901068 144 0.039
cytokine production GO:0001816 319 0.039
negative regulation of ligase activity GO:0051352 3 0.039
connective tissue development GO:0061448 179 0.039
regulation of jnk cascade GO:0046328 62 0.039
Mouse
negative regulation of bmp signaling pathway GO:0030514 35 0.039
Fly
positive regulation of cell projection organization GO:0031346 95 0.039
cell cell junction organization GO:0045216 72 0.039
Mouse
gtp metabolic process GO:0046039 144 0.039
synapse organization GO:0050808 125 0.038
Mouse
molting cycle GO:0042303 90 0.038
regulation of neuron projection development GO:0010975 169 0.038
Mouse
synapse assembly GO:0007416 56 0.038
hair cycle GO:0042633 90 0.038
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.038
kidney development GO:0001822 213 0.038
nuclear import GO:0051170 95 0.038
regulation of muscle tissue development GO:1901861 97 0.038
cell junction organization GO:0034330 77 0.038
Mouse
protein localization to nucleus GO:0034504 121 0.038
positive regulation of nervous system development GO:0051962 221 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.037
regulation of t cell anergy GO:0002667 4 0.037
Mouse
skin development GO:0043588 220 0.037
single organism cell adhesion GO:0098602 156 0.037
formation of primary germ layer GO:0001704 77 0.037
response to bmp GO:0071772 14 0.037
spermatid differentiation GO:0048515 115 0.037
multi organism behavior GO:0051705 62 0.036
regulation of gtp catabolic process GO:0033124 113 0.036
purine containing compound metabolic process GO:0072521 311 0.036
wnt signaling pathway GO:0016055 188 0.036
peptidyl amino acid modification GO:0018193 336 0.036
regulation of rho protein signal transduction GO:0035023 71 0.036
developmental growth involved in morphogenesis GO:0060560 138 0.036
nucleoside catabolic process GO:0009164 206 0.035
purine nucleotide metabolic process GO:0006163 302 0.035
leukocyte differentiation GO:0002521 342 0.035
epithelial tube morphogenesis GO:0060562 303 0.035
stem cell differentiation GO:0048863 268 0.035
primary neural tube formation GO:0014020 95 0.034
response to monosaccharide GO:0034284 67 0.034
myeloid cell differentiation GO:0030099 233 0.034
regulation of bmp signaling pathway GO:0030510 60 0.034
Fly
regulation of cellular protein catabolic process GO:1903362 61 0.034
protein modification by small protein conjugation or removal GO:0070647 207 0.034
regulation of proteolysis GO:0030162 164 0.034
regulation of cellular response to stress GO:0080135 159 0.034
Mouse
cell fate commitment GO:0045165 210 0.034
reproductive behavior GO:0019098 32 0.034
ribonucleoside catabolic process GO:0042454 206 0.033
cellular response to lipid GO:0071396 145 0.033
blood circulation GO:0008015 195 0.033
Mouse
neural tube formation GO:0001841 108 0.033
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
sebaceous gland development GO:0048733 7 0.033
organ growth GO:0035265 117 0.033
outflow tract morphogenesis GO:0003151 53 0.033
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.032
endomembrane system organization GO:0010256 147 0.032
actin filament organization GO:0007015 113 0.032
liver development GO:0001889 66 0.032
regulation of nucleoside metabolic process GO:0009118 130 0.032
peptide secretion GO:0002790 114 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.032
epidermis development GO:0008544 187 0.032
organic cyclic compound catabolic process GO:1901361 295 0.032
nucleoside triphosphate metabolic process GO:0009141 230 0.031
transmembrane transport GO:0055085 412 0.031
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.031
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.031
Mouse
gonad development GO:0008406 141 0.031
wound healing GO:0042060 157 0.031
negative regulation of smad protein complex assembly GO:0010991 1 0.031
digestive tract morphogenesis GO:0048546 147 0.031
Fly
stem cell proliferation GO:0072089 117 0.031
muscle cell development GO:0055001 133 0.031
positive regulation of protein transport GO:0051222 93 0.031
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.031
insulin secretion GO:0030073 89 0.031
protein localization to membrane GO:0072657 108 0.031
single organismal cell cell adhesion GO:0016337 131 0.031
embryonic skeletal system morphogenesis GO:0048704 91 0.030
purine nucleotide catabolic process GO:0006195 211 0.030
neural tube closure GO:0001843 90 0.030
negative regulation of osteoblast differentiation GO:0045668 30 0.030
muscle cell differentiation GO:0042692 261 0.030
cell substrate adhesion GO:0031589 130 0.030
maintenance of location GO:0051235 89 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.030
peptide hormone secretion GO:0030072 109 0.030
regulation of cell cycle process GO:0010564 160 0.029
positive regulation of cellular protein catabolic process GO:1903364 34 0.029
lymphocyte proliferation GO:0046651 164 0.029
Mouse
regulation of t cell activation GO:0050863 170 0.029
Mouse
nuclear division GO:0000280 158 0.029
t cell anergy GO:0002870 4 0.028
Mouse
organelle localization GO:0051640 179 0.028
microtubule based process GO:0007017 236 0.028
regulation of synapse assembly GO:0051963 29 0.028
chromatin organization GO:0006325 206 0.028
regulation of lymphocyte anergy GO:0002911 4 0.028
Mouse
regulation of proteasomal protein catabolic process GO:0061136 46 0.028
negative regulation of intracellular signal transduction GO:1902532 167 0.028
Mouse
hormone secretion GO:0046879 128 0.028
retinal ganglion cell axon guidance GO:0031290 18 0.027
forebrain development GO:0030900 302 0.027
cardiac septum development GO:0003279 59 0.027
negative regulation of ossification GO:0030279 49 0.027
purine nucleoside triphosphate metabolic process GO:0009144 226 0.027
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.027
Mouse
negative regulation of nervous system development GO:0051961 156 0.027
negative regulation of wound healing GO:0061045 14 0.027
cell type specific apoptotic process GO:0097285 268 0.027
pathway restricted smad protein phosphorylation GO:0060389 10 0.026
regulation of lymphocyte proliferation GO:0050670 117 0.026
Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.026
cell division GO:0051301 120 0.026
striated muscle tissue development GO:0014706 293 0.026
fat cell differentiation GO:0045444 160 0.026
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.026
purine nucleoside catabolic process GO:0006152 205 0.026
ion transmembrane transport GO:0034220 361 0.026
Mouse
spermatid development GO:0007286 108 0.025
positive regulation of protein ubiquitination GO:0031398 27 0.025
erythrocyte differentiation GO:0030218 88 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
gastrulation GO:0007369 116 0.025
regulation of osteoblast proliferation GO:0033688 15 0.024
regulation of leukocyte differentiation GO:1902105 159 0.024
t cell proliferation GO:0042098 120 0.024
Mouse
positive regulation of cell adhesion GO:0045785 80 0.024
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.024
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
endodermal cell fate specification GO:0001714 4 0.024
regulation of ras protein signal transduction GO:0046578 114 0.024
regulation of protein localization to nucleus GO:1900180 60 0.024
positive regulation of nucleotide metabolic process GO:0045981 114 0.024
epithelial cell proliferation GO:0050673 174 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.024
striated muscle cell development GO:0055002 125 0.023
multicellular organism growth GO:0035264 161 0.023
positive regulation of neuron projection development GO:0010976 79 0.023
stem cell maintenance GO:0019827 130 0.023
epithelial tube formation GO:0072175 130 0.023
multi organism reproductive behavior GO:0044705 29 0.023
regulation of ligase activity GO:0051340 10 0.023
cardiac chamber development GO:0003205 108 0.023
organophosphate catabolic process GO:0046434 232 0.023
axon guidance GO:0007411 141 0.023
cellular homeostasis GO:0019725 240 0.023
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.023
Human Mouse Fly
negative regulation of lymphocyte activation GO:0051250 91 0.023
Mouse
positive regulation of lymphocyte anergy GO:0002913 4 0.023
Mouse
stem cell development GO:0048864 219 0.022
regulation of t cell proliferation GO:0042129 92 0.022
Mouse
positive regulation of gtpase activity GO:0043547 85 0.022
regulation of ossification GO:0030278 112 0.022
regulation of binding GO:0051098 111 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
positive regulation of gtp catabolic process GO:0033126 85 0.022
meiotic nuclear division GO:0007126 115 0.022
inorganic ion transmembrane transport GO:0098660 234 0.022
Mouse
adherens junction assembly GO:0034333 22 0.022
regulation of map kinase activity GO:0043405 120 0.022
regulation of anatomical structure size GO:0090066 178 0.022
cell growth GO:0016049 130 0.022
positive regulation of t cell anergy GO:0002669 4 0.022
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.022
tube formation GO:0035148 140 0.022
meiotic cell cycle GO:0051321 122 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.021
negative regulation of cell activation GO:0050866 111 0.021
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.021
adult behavior GO:0030534 135 0.021
regulation of smad protein complex assembly GO:0010990 1 0.021
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.021
regulation of cellular component size GO:0032535 121 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
positive regulation of nucleoside metabolic process GO:0045979 91 0.021
nephron development GO:0072006 109 0.021
covalent chromatin modification GO:0016569 163 0.021
myeloid leukocyte differentiation GO:0002573 119 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
Mouse
sensory perception GO:0007600 245 0.020
smoothened signaling pathway GO:0007224 105 0.020
hindbrain development GO:0030902 128 0.020
cation transmembrane transport GO:0098655 266 0.020
Mouse
extracellular matrix organization GO:0030198 147 0.020
regulation of stem cell differentiation GO:2000736 50 0.020
regulation of ras gtpase activity GO:0032318 88 0.020
regulation of cytokine production GO:0001817 266 0.020
regulation of chromosome organization GO:0033044 83 0.020
adaptive immune response GO:0002250 155 0.020
Mouse
regulation of cellular catabolic process GO:0031329 242 0.020
mesoderm development GO:0007498 100 0.020
apoptotic signaling pathway GO:0097190 306 0.020
development of primary sexual characteristics GO:0045137 143 0.020
palate development GO:0060021 76 0.020
response to sterol GO:0036314 4 0.020
negative regulation of t cell activation GO:0050868 65 0.020
Mouse
purine nucleoside metabolic process GO:0042278 241 0.020
tube closure GO:0060606 91 0.020
osteoblast development GO:0002076 17 0.020
regulation of osteoblast differentiation GO:0045667 67 0.019
inorganic cation transmembrane transport GO:0098662 207 0.019
Mouse
establishment of planar polarity GO:0001736 28 0.019
lymphocyte anergy GO:0002249 4 0.019
Mouse
smad protein signal transduction GO:0060395 21 0.019
gtp catabolic process GO:0006184 143 0.019
endoderm development GO:0007492 45 0.019
somite development GO:0061053 81 0.019
regulation of protein catabolic process GO:0042176 108 0.019
Mouse
blastocyst development GO:0001824 80 0.019
synaptic transmission GO:0007268 329 0.019
Mouse
negative regulation of protein complex assembly GO:0031333 25 0.019
embryonic placenta development GO:0001892 98 0.019
regulation of organ morphogenesis GO:2000027 144 0.019
g protein coupled receptor signaling pathway GO:0007186 243 0.019
negative regulation of lymphocyte proliferation GO:0050672 45 0.019
Mouse
compound eye development GO:0048749 1 0.019
t cell differentiation GO:0030217 174 0.019
glycosyl compound metabolic process GO:1901657 246 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.019
renal tubule morphogenesis GO:0061333 72 0.019
ameboidal type cell migration GO:0001667 128 0.018
negative regulation of apoptotic signaling pathway GO:2001234 104 0.018
p38mapk cascade GO:0038066 4 0.018
cellular component assembly involved in morphogenesis GO:0010927 139 0.018
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.018
asymmetric neuroblast division GO:0055059 1 0.018
guanosine containing compound catabolic process GO:1901069 144 0.018
nucleoside metabolic process GO:0009116 246 0.018
segmentation GO:0035282 93 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
multicellular organismal reproductive behavior GO:0033057 23 0.018
cardiac ventricle development GO:0003231 83 0.018
positive regulation of nucleotide catabolic process GO:0030813 88 0.018
nephron epithelium development GO:0072009 92 0.018
response to organonitrogen compound GO:0010243 246 0.018
chromosome segregation GO:0007059 48 0.018
morphogenesis of a branching epithelium GO:0061138 193 0.018
positive regulation of organelle organization GO:0010638 128 0.018
asymmetric stem cell division GO:0098722 3 0.018
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.017
regulation of ion transmembrane transport GO:0034765 119 0.017
Mouse
b cell activation GO:0042113 161 0.017
mesonephros development GO:0001823 97 0.017
cell junction maintenance GO:0034331 4 0.017
regulation of transporter activity GO:0032409 57 0.017
Mouse
formation of anatomical boundary GO:0048859 6 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
protein maturation GO:0051604 176 0.017
regulation of hippo signaling GO:0035330 1 0.017
endocrine system development GO:0035270 98 0.017
regulation of blood pressure GO:0008217 93 0.017
Mouse
regulation of protein ubiquitination GO:0031396 52 0.017
mesoderm morphogenesis GO:0048332 64 0.017
regulation of leukocyte proliferation GO:0070663 121 0.017
Mouse
organelle fission GO:0048285 170 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
defense response to other organism GO:0098542 197 0.017
Mouse
alpha beta t cell activation GO:0046631 91 0.017
Mouse
regulation of cell motility GO:2000145 236 0.017
ureteric bud development GO:0001657 94 0.017
positive regulation of map kinase activity GO:0043406 84 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017

Smurf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.125
cancer DOID:162 0 0.104
organ system cancer DOID:0050686 0 0.104
disease of anatomical entity DOID:7 0 0.091
cardiovascular system disease DOID:1287 0 0.091
heart disease DOID:114 0 0.078
musculoskeletal system disease DOID:17 0 0.022
gastrointestinal system cancer DOID:3119 0 0.019