Mus musculus

0 known processes

Slx4

SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)

(Aliases: D16Bwg1016e,Btbd12,AI256635,AI426760)

Slx4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.056
Human
nucleobase containing small molecule metabolic process GO:0055086 352 0.047
regulation of cellular catabolic process GO:0031329 242 0.045
cellular amino acid metabolic process GO:0006520 103 0.044
cellular ketone metabolic process GO:0042180 84 0.044
cellular amine metabolic process GO:0044106 44 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
macromolecule catabolic process GO:0009057 281 0.041
Human
amine metabolic process GO:0009308 45 0.039
cation transport GO:0006812 399 0.039
regulation of cellular ketone metabolic process GO:0010565 66 0.039
cellular response to dna damage stimulus GO:0006974 207 0.035
Human
nucleotide metabolic process GO:0009117 332 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
ribonucleotide metabolic process GO:0009259 291 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.035
nucleoside metabolic process GO:0009116 246 0.034
spermatogenesis GO:0007283 284 0.033
cellular component assembly involved in morphogenesis GO:0010927 139 0.033
heterocycle catabolic process GO:0046700 280 0.032
Human
organelle assembly GO:0070925 177 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
cellular lipid metabolic process GO:0044255 323 0.031
male gamete generation GO:0048232 285 0.031
regulation of organelle organization GO:0033043 289 0.031
purine ribonucleoside metabolic process GO:0046128 241 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
transmembrane transport GO:0055085 412 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.030
Human
purine nucleoside metabolic process GO:0042278 241 0.030
positive regulation of protein phosphorylation GO:0001934 242 0.030
purine containing compound metabolic process GO:0072521 311 0.030
ras protein signal transduction GO:0007265 77 0.029
organonitrogen compound catabolic process GO:1901565 264 0.029
peptidyl amino acid modification GO:0018193 336 0.029
organic cyclic compound catabolic process GO:1901361 295 0.028
Human
intracellular protein transport GO:0006886 204 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
purine nucleotide catabolic process GO:0006195 211 0.028
glycosyl compound metabolic process GO:1901657 246 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.027
microtubule cytoskeleton organization GO:0000226 157 0.027
mitotic cell cycle GO:0000278 195 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
striated muscle tissue development GO:0014706 293 0.027
response to organonitrogen compound GO:0010243 246 0.026
membrane organization GO:0061024 245 0.026
regulation of transferase activity GO:0051338 263 0.026
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
small gtpase mediated signal transduction GO:0007264 97 0.026
anion transport GO:0006820 177 0.026
negative regulation of cellular amine metabolic process GO:0033239 1 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.025
nucleotide catabolic process GO:0009166 217 0.025
organophosphate catabolic process GO:0046434 232 0.025
leukocyte differentiation GO:0002521 342 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
inorganic ion transmembrane transport GO:0098660 234 0.025
positive regulation of protein modification process GO:0031401 299 0.025
muscle tissue development GO:0060537 308 0.025
actin cytoskeleton organization GO:0030036 220 0.025
apoptotic signaling pathway GO:0097190 306 0.024
reactive oxygen species metabolic process GO:0072593 84 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
muscle cell differentiation GO:0042692 261 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
Human
purine containing compound catabolic process GO:0072523 213 0.023
microtubule based process GO:0007017 236 0.023
organonitrogen compound biosynthetic process GO:1901566 192 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.023
protein processing GO:0016485 163 0.023
endomembrane system organization GO:0010256 147 0.023
protein catabolic process GO:0030163 221 0.022
regulation of hydrolase activity GO:0051336 246 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
positive regulation of cellular catabolic process GO:0031331 148 0.022
cytoplasmic transport GO:0016482 234 0.022
regulation of cell cycle GO:0051726 281 0.022
cellular homeostasis GO:0019725 240 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
cytokine production GO:0001816 319 0.022
homeostasis of number of cells GO:0048872 210 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
cell type specific apoptotic process GO:0097285 268 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
dna repair GO:0006281 107 0.021
Human
purine ribonucleotide catabolic process GO:0009154 208 0.021
cation transmembrane transport GO:0098655 266 0.021
aromatic compound catabolic process GO:0019439 286 0.021
Human
myeloid cell differentiation GO:0030099 233 0.021
ion transmembrane transport GO:0034220 361 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
protein maturation GO:0051604 176 0.021
germ cell development GO:0007281 185 0.021
regulation of nucleotide catabolic process GO:0030811 122 0.020
regulation of kinase activity GO:0043549 249 0.020
modification dependent protein catabolic process GO:0019941 133 0.020
embryonic organ morphogenesis GO:0048562 276 0.020
regulation of protein localization GO:0032880 231 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
oxidation reduction process GO:0055114 342 0.020
regulation of mapk cascade GO:0043408 248 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
organic anion transport GO:0015711 137 0.020
regulation of anatomical structure size GO:0090066 178 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
cellular chemical homeostasis GO:0055082 215 0.019
protein ubiquitination GO:0016567 171 0.019
spermatid differentiation GO:0048515 115 0.019
rho protein signal transduction GO:0007266 32 0.019
lymphocyte differentiation GO:0030098 242 0.019
regulation of membrane potential GO:0042391 192 0.019
nucleoside catabolic process GO:0009164 206 0.019
regulation of cellular response to stress GO:0080135 159 0.019
negative regulation of molecular function GO:0044092 258 0.019
spermatid development GO:0007286 108 0.018
cilium assembly GO:0042384 81 0.018
glycerolipid metabolic process GO:0046486 122 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
nuclear transport GO:0051169 139 0.018
regulation of neuron differentiation GO:0045664 281 0.018
chemotaxis GO:0006935 247 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
protein localization to organelle GO:0033365 185 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
cellular protein catabolic process GO:0044257 155 0.018
t cell activation GO:0042110 289 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
regulation of mitotic cell cycle GO:0007346 126 0.017
regulation of protein kinase activity GO:0045859 232 0.017
cation homeostasis GO:0055080 212 0.017
positive regulation of cell death GO:0010942 224 0.017
nitrogen compound transport GO:0071705 271 0.017
mitotic cell cycle process GO:1903047 159 0.017
regulation of cellular component size GO:0032535 121 0.017
regulation of cell activation GO:0050865 289 0.017
engulfment of apoptotic cell GO:0043652 3 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
mapk cascade GO:0000165 281 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
cellular ion homeostasis GO:0006873 165 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
cellular protein complex assembly GO:0043623 116 0.017
regulation of metal ion transport GO:0010959 106 0.017
regulation of intracellular transport GO:0032386 159 0.017
organelle fission GO:0048285 170 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
negative regulation of protein modification process GO:0031400 163 0.016
fertilization GO:0009566 127 0.016
regulation of secretion by cell GO:1903530 249 0.016
camera type eye development GO:0043010 266 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
cilium morphogenesis GO:0060271 102 0.016
carbohydrate metabolic process GO:0005975 230 0.016
chromatin organization GO:0006325 206 0.016
covalent chromatin modification GO:0016569 163 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
skeletal system development GO:0001501 356 0.016
small molecule biosynthetic process GO:0044283 132 0.016
lipid biosynthetic process GO:0008610 179 0.016
histone modification GO:0016570 159 0.016
heart morphogenesis GO:0003007 178 0.016
glycoprotein metabolic process GO:0009100 116 0.016
gtp catabolic process GO:0006184 143 0.016
nuclear division GO:0000280 158 0.016
regulation of ion transport GO:0043269 215 0.016
mrna metabolic process GO:0016071 84 0.016
metal ion homeostasis GO:0055065 189 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
glucose homeostasis GO:0042593 128 0.016
sensory perception GO:0007600 245 0.015
stem cell differentiation GO:0048863 268 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
response to inorganic substance GO:0010035 96 0.015
compound eye development GO:0048749 1 0.015
response to light stimulus GO:0009416 135 0.015
positive regulation of nervous system development GO:0051962 221 0.015
regulation of proteolysis GO:0030162 164 0.015
negative regulation of immune system process GO:0002683 209 0.015
cell growth GO:0016049 130 0.015
regulation of protein transport GO:0051223 163 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
rna processing GO:0006396 105 0.015
protein targeting GO:0006605 143 0.015
regulation of cell cycle process GO:0010564 160 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
regulation of secretion GO:0051046 274 0.014
gland development GO:0048732 330 0.014
immune effector process GO:0002252 321 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
gtp metabolic process GO:0046039 144 0.014
organic acid transport GO:0015849 101 0.014
guanosine containing compound metabolic process GO:1901068 144 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
regulation of cytokine production GO:0001817 266 0.014
response to oxidative stress GO:0006979 123 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
response to radiation GO:0009314 165 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
divalent inorganic cation transport GO:0072511 178 0.014
regulation of cell projection organization GO:0031344 206 0.014
calcium ion transport GO:0006816 159 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
regulation of t cell activation GO:0050863 170 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
leukocyte migration GO:0050900 124 0.014
response to growth factor GO:0070848 198 0.014
oocyte construction GO:0007308 2 0.014
ossification GO:0001503 216 0.014
oocyte axis specification GO:0007309 2 0.014
regionalization GO:0003002 337 0.014
positive regulation of cell development GO:0010720 237 0.014
development of primary sexual characteristics GO:0045137 143 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
meiotic cell cycle GO:0051321 122 0.014
fatty acid metabolic process GO:0006631 121 0.013
macromolecule methylation GO:0043414 120 0.013
positive regulation of transferase activity GO:0051347 167 0.013
protein localization to membrane GO:0072657 108 0.013
mitochondrion organization GO:0007005 134 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
leukocyte proliferation GO:0070661 172 0.013
cell adhesion GO:0007155 329 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
regulation of protein catabolic process GO:0042176 108 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
positive regulation of kinase activity GO:0033674 155 0.013
methylation GO:0032259 134 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
regulation of cell motility GO:2000145 236 0.013
sequestering of metal ion GO:0051238 19 0.013
epithelial cell development GO:0002064 159 0.013
cell division GO:0051301 120 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
axonogenesis GO:0007409 274 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
endocytosis GO:0006897 168 0.013
negative regulation of cell development GO:0010721 169 0.013
synaptic transmission GO:0007268 329 0.013
digestive system development GO:0055123 200 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
divalent metal ion transport GO:0070838 172 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
regulation of body fluid levels GO:0050878 162 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
exocytosis GO:0006887 121 0.013
sequestering of calcium ion GO:0051208 18 0.013
sensory organ morphogenesis GO:0090596 242 0.013
regulation of homeostatic process GO:0032844 182 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
acetylcholine secretion neurotransmission GO:0014055 2 0.013
forebrain development GO:0030900 302 0.013
chromatin modification GO:0016568 187 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
phospholipid metabolic process GO:0006644 87 0.012
developmental maturation GO:0021700 193 0.012
b cell activation GO:0042113 161 0.012
regulation of chromosome organization GO:0033044 83 0.012
maintenance of location GO:0051235 89 0.012
retrograde transport endosome to golgi GO:0042147 2 0.012
asymmetric stem cell division GO:0098722 3 0.012
angiogenesis GO:0001525 201 0.012
smoothened signaling pathway GO:0007224 105 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
regulation of ral gtpase activity GO:0032315 4 0.012
protein secretion GO:0009306 111 0.012
carboxylic acid transport GO:0046942 100 0.012
anatomical structure homeostasis GO:0060249 145 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
blood circulation GO:0008015 195 0.012
negative regulation of proteolysis GO:0045861 74 0.012
translation GO:0006412 93 0.012
neural tube formation GO:0001841 108 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
fat cell differentiation GO:0045444 160 0.012
positive regulation of cilium movement GO:0003353 1 0.012
response to acid chemical GO:0001101 111 0.012
skeletal system morphogenesis GO:0048705 203 0.012
protein alkylation GO:0008213 81 0.012
alcohol metabolic process GO:0006066 116 0.012
epithelial cell proliferation GO:0050673 174 0.012
actin filament organization GO:0007015 113 0.012
positive regulation of organelle organization GO:0010638 128 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
regulation of translation GO:0006417 71 0.011
blood vessel morphogenesis GO:0048514 285 0.011
regulation of binding GO:0051098 111 0.011
respiratory system development GO:0060541 190 0.011
cytokinetic process GO:0032506 2 0.011
positive regulation of cell activation GO:0050867 158 0.011
response to lipopolysaccharide GO:0032496 128 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
negative regulation of organelle organization GO:0010639 90 0.011
renal system development GO:0072001 225 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
negative regulation of cell cycle GO:0045786 123 0.011
neuron death GO:0070997 154 0.011
cell activation involved in immune response GO:0002263 126 0.011
mitotic cytokinesis GO:0000281 4 0.011
single organism cell adhesion GO:0098602 156 0.011
regulation of neuron death GO:1901214 134 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
lipid localization GO:0010876 126 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
appendage development GO:0048736 166 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
regulation of hormone levels GO:0010817 211 0.011
inflammatory response GO:0006954 244 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
regulation of system process GO:0044057 200 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
regulation of neuron projection development GO:0010975 169 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
organic acid biosynthetic process GO:0016053 86 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
myosin filament organization GO:0031033 3 0.011
atp metabolic process GO:0046034 75 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
calcium ion homeostasis GO:0055074 127 0.010
bone development GO:0060348 120 0.010
gonad development GO:0008406 141 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
circulatory system process GO:0003013 197 0.010
lymphocyte proliferation GO:0046651 164 0.010
multi multicellular organism process GO:0044706 109 0.010
positive regulation of protein catabolic process GO:0045732 60 0.010
peptidyl serine modification GO:0018209 83 0.010
cofactor metabolic process GO:0051186 80 0.010
locomotory behavior GO:0007626 195 0.010
connective tissue development GO:0061448 179 0.010
muscle system process GO:0003012 141 0.010
myeloid cell homeostasis GO:0002262 114 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
myosin filament assembly GO:0031034 2 0.010
protein localization to nucleus GO:0034504 121 0.010
meiotic nuclear division GO:0007126 115 0.010
regulation of cell migration GO:0030334 219 0.010
cellular response to biotic stimulus GO:0071216 92 0.010
Human
female gamete generation GO:0007292 74 0.010
leukocyte activation involved in immune response GO:0002366 126 0.010
regulation of protein processing GO:0070613 96 0.010
sulfur compound metabolic process GO:0006790 100 0.010

Slx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
Human
nervous system disease DOID:863 0 0.029
immune system disease DOID:2914 0 0.027
Human
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
organ system cancer DOID:0050686 0 0.025
musculoskeletal system disease DOID:17 0 0.017
central nervous system disease DOID:331 0 0.017
hematopoietic system disease DOID:74 0 0.016
Human
bone disease DOID:0080001 0 0.012
connective tissue disease DOID:65 0 0.012
disease of metabolism DOID:0014667 0 0.011