Mus musculus

66 known processes

Pdcd6

programmed cell death 6

(Aliases: Alg2,PS2,MA-3,AV299538,alg-2)

Pdcd6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.661
cellular protein catabolic process GO:0044257 155 0.250
transmembrane transport GO:0055085 412 0.235
modification dependent macromolecule catabolic process GO:0043632 133 0.233
ion transmembrane transport GO:0034220 361 0.221
cellular macromolecule catabolic process GO:0044265 206 0.193
organelle assembly GO:0070925 177 0.181
modification dependent protein catabolic process GO:0019941 133 0.174
viral budding GO:0046755 1 0.145
regulation of organelle organization GO:0033043 289 0.126
regulation of cellular component biogenesis GO:0044087 181 0.120
cofactor metabolic process GO:0051186 80 0.105
protein maturation GO:0051604 176 0.104
cation transmembrane transport GO:0098655 266 0.101
exosomal secretion GO:1990182 1 0.095
nucleotide metabolic process GO:0009117 332 0.092
ubiquitin dependent protein catabolic process GO:0006511 129 0.074
negative regulation of cellular component organization GO:0051129 194 0.072
sphingolipid biosynthetic process GO:0030148 26 0.071
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.071
pigment biosynthetic process GO:0046148 26 0.070
virion assembly GO:0019068 1 0.066
protein catabolic process GO:0030163 221 0.062
protein modification by small protein conjugation or removal GO:0070647 207 0.061
apoptotic mitochondrial changes GO:0008637 48 0.058
oxidation reduction process GO:0055114 342 0.058
stem cell differentiation GO:0048863 268 0.057
lipid homeostasis GO:0055088 63 0.057
cell growth GO:0016049 130 0.056
microtubule based process GO:0007017 236 0.055
response to organonitrogen compound GO:0010243 246 0.054
interspecies interaction between organisms GO:0044419 83 0.052
cation transport GO:0006812 399 0.050
Mouse
protein processing GO:0016485 163 0.050
membrane organization GO:0061024 245 0.049
cellular protein complex assembly GO:0043623 116 0.047
inorganic ion transmembrane transport GO:0098660 234 0.047
inorganic cation transmembrane transport GO:0098662 207 0.046
vesicle organization GO:0016050 60 0.046
macromolecule catabolic process GO:0009057 281 0.045
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.045
negative regulation of cell proliferation GO:0008285 296 0.044
peroxisomal transport GO:0043574 4 0.044
purine ribonucleoside metabolic process GO:0046128 241 0.044
amine metabolic process GO:0009308 45 0.044
positive regulation of organelle organization GO:0010638 128 0.043
regulation of vesicle mediated transport GO:0060627 139 0.043
viral process GO:0016032 41 0.043
regulation of cellular amine metabolic process GO:0033238 20 0.042
protein modification by small protein conjugation GO:0032446 187 0.040
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.039
cellular amine metabolic process GO:0044106 44 0.039
cellular amino acid metabolic process GO:0006520 103 0.038
cytoplasmic transport GO:0016482 234 0.038
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.037
regulation of secretion by cell GO:1903530 249 0.037
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.037
nucleoside metabolic process GO:0009116 246 0.037
protein ubiquitination GO:0016567 171 0.036
organonitrogen compound catabolic process GO:1901565 264 0.036
nitrogen compound transport GO:0071705 271 0.036
Mouse
glycosyl compound metabolic process GO:1901657 246 0.036
lipid biosynthetic process GO:0008610 179 0.035
cellular response to lipid GO:0071396 145 0.035
positive regulation of proteolysis GO:0045862 85 0.034
establishment or maintenance of cell polarity GO:0007163 86 0.034
morphogenesis of embryonic epithelium GO:0016331 159 0.034
regulation of cytoskeleton organization GO:0051493 122 0.034
cellular homeostasis GO:0019725 240 0.034
Mouse
positive regulation of cell death GO:0010942 224 0.033
locomotory behavior GO:0007626 195 0.032
neural tube development GO:0021915 160 0.031
synaptic transmission GO:0007268 329 0.031
positive regulation of secretion GO:0051047 130 0.031
Mouse
mapk cascade GO:0000165 281 0.031
ribonucleoside metabolic process GO:0009119 245 0.031
positive regulation of kinase activity GO:0033674 155 0.031
apoptotic signaling pathway GO:0097190 306 0.030
regulation of anatomical structure size GO:0090066 178 0.030
regulation of exocytosis GO:0017157 61 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
regulation of proteolysis GO:0030162 164 0.029
cellular ketone metabolic process GO:0042180 84 0.029
microtubule cytoskeleton organization GO:0000226 157 0.029
ribose phosphate metabolic process GO:0019693 291 0.028
ras protein signal transduction GO:0007265 77 0.028
ameboidal type cell migration GO:0001667 128 0.028
engulfment of apoptotic cell GO:0043652 3 0.028
proteasomal protein catabolic process GO:0010498 98 0.028
regulation of cell growth GO:0001558 91 0.027
carboxylic acid catabolic process GO:0046395 51 0.027
cellular lipid metabolic process GO:0044255 323 0.027
cation homeostasis GO:0055080 212 0.027
Mouse
regulation of multi organism process GO:0043900 111 0.027
spermatogenesis GO:0007283 284 0.027
exocytosis GO:0006887 121 0.027
neural tube formation GO:0001841 108 0.026
positive regulation of secretion by cell GO:1903532 114 0.026
Mouse
stem cell maintenance GO:0019827 130 0.026
blood vessel morphogenesis GO:0048514 285 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.026
gland development GO:0048732 330 0.026
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.025
meiotic cell cycle GO:0051321 122 0.025
purine containing compound catabolic process GO:0072523 213 0.025
heterocycle catabolic process GO:0046700 280 0.025
cellular chemical homeostasis GO:0055082 215 0.025
Mouse
membrane lipid biosynthetic process GO:0046467 32 0.024
male gamete generation GO:0048232 285 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
purine nucleobase metabolic process GO:0006144 4 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
oocyte axis specification GO:0007309 2 0.023
protein localization to organelle GO:0033365 185 0.023
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.023
epithelial tube formation GO:0072175 130 0.022
meiotic cell cycle process GO:1903046 77 0.022
regulation of hydrolase activity GO:0051336 246 0.022
purine nucleobase biosynthetic process GO:0009113 3 0.022
negative regulation of protein metabolic process GO:0051248 282 0.022
negative regulation of apoptotic signaling pathway GO:2001234 104 0.022
regulation of secretion GO:0051046 274 0.022
Mouse
purine nucleotide metabolic process GO:0006163 302 0.022
protein oligomerization GO:0051259 67 0.022
asymmetric stem cell division GO:0098722 3 0.021
nucleoside monophosphate metabolic process GO:0009123 85 0.021
regulation of cell cycle GO:0051726 281 0.021
cellular metal ion homeostasis GO:0006875 151 0.021
Mouse
regulation of mitochondrion organization GO:0010821 27 0.021
positive regulation of protein modification process GO:0031401 299 0.020
regulation of hormone levels GO:0010817 211 0.020
Mouse
response to organic cyclic compound GO:0014070 198 0.020
regulation of lipid metabolic process GO:0019216 118 0.020
regulation of cellular amino acid metabolic process GO:0006521 5 0.020
sulfur compound metabolic process GO:0006790 100 0.020
cellular ion homeostasis GO:0006873 165 0.020
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.020
purine nucleoside monophosphate metabolic process GO:0009126 81 0.020
negative regulation of organelle organization GO:0010639 90 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
regulation of response to wounding GO:1903034 189 0.019
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
stem cell development GO:0048864 219 0.019
protein polymerization GO:0051258 57 0.019
organelle fission GO:0048285 170 0.019
regulation of ion transmembrane transporter activity GO:0032412 54 0.019
mitotic cell cycle GO:0000278 195 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.019
anion transport GO:0006820 177 0.019
cellular response to dna damage stimulus GO:0006974 207 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.019
protein import GO:0017038 101 0.018
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.018
leukocyte proliferation GO:0070661 172 0.018
embryonic epithelial tube formation GO:0001838 130 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
intracellular protein transport GO:0006886 204 0.018
Mouse
negative regulation of molecular function GO:0044092 258 0.018
Mouse
purine containing compound metabolic process GO:0072521 311 0.018
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.018
steroid metabolic process GO:0008202 119 0.018
atp metabolic process GO:0046034 75 0.018
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.018
regulation of protein complex assembly GO:0043254 83 0.017
pole plasm assembly GO:0007315 2 0.017
establishment of protein localization to organelle GO:0072594 118 0.017
Mouse
regulation of actin filament length GO:0030832 45 0.017
sphingolipid metabolic process GO:0006665 45 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
embryonic organ morphogenesis GO:0048562 276 0.017
axonogenesis GO:0007409 274 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
ribonucleoside monophosphate metabolic process GO:0009161 80 0.017
response to oxidative stress GO:0006979 123 0.017
sterol metabolic process GO:0016125 58 0.017
epithelium migration GO:0090132 63 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
wnt signaling pathway GO:0016055 188 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
skin development GO:0043588 220 0.017
nucleoside phosphate biosynthetic process GO:1901293 79 0.017
endocytosis GO:0006897 168 0.017
regulation of defense response GO:0031347 233 0.017
organic cyclic compound catabolic process GO:1901361 295 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.016
response to inorganic substance GO:0010035 96 0.016
regulation of cell motility GO:2000145 236 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.016
regulation of inflammatory response GO:0050727 147 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
positive regulation of exocytosis GO:0045921 20 0.016
cell maturation GO:0048469 127 0.016
mitotic cell cycle process GO:1903047 159 0.016
regulation of cell substrate adhesion GO:0010810 73 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
retrograde transport endosome to golgi GO:0042147 2 0.015
nucleoside monophosphate catabolic process GO:0009125 59 0.015
establishment of vesicle localization GO:0051650 81 0.015
regulation of neuron differentiation GO:0045664 281 0.015
sensory perception GO:0007600 245 0.015
nucleoside catabolic process GO:0009164 206 0.015
organic acid biosynthetic process GO:0016053 86 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
regulation of cellular component size GO:0032535 121 0.015
extracellular structure organization GO:0043062 148 0.015
regulation of cell migration GO:0030334 219 0.015
maternal determination of anterior posterior axis embryo GO:0008358 2 0.015
positive regulation of cytoskeleton organization GO:0051495 49 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
regulation of protein catabolic process GO:0042176 108 0.015
neuron migration GO:0001764 122 0.015
positive regulation of cell development GO:0010720 237 0.015
synapse organization GO:0050808 125 0.015
cell division GO:0051301 120 0.014
epidermis development GO:0008544 187 0.014
cofactor transport GO:0051181 4 0.014
small molecule biosynthetic process GO:0044283 132 0.014
divalent inorganic cation transport GO:0072511 178 0.014
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
mitochondrion organization GO:0007005 134 0.014
erbb signaling pathway GO:0038127 32 0.014
glycerolipid biosynthetic process GO:0045017 50 0.014
protein targeting to peroxisome GO:0006625 4 0.014
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.014
extracellular matrix organization GO:0030198 147 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
regulation of protein transport GO:0051223 163 0.014
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.013
Mouse
developmental cell growth GO:0048588 84 0.013
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 6 0.013
actin filament organization GO:0007015 113 0.013
positive regulation of cell cycle process GO:0090068 61 0.013
regulation of reproductive process GO:2000241 66 0.013
l ascorbic acid metabolic process GO:0019852 4 0.013
epithelial cell migration GO:0010631 63 0.013
inflammatory response GO:0006954 244 0.013
pigment metabolic process GO:0042440 32 0.013
cell type specific apoptotic process GO:0097285 268 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
negative regulation of response to wounding GO:1903035 77 0.013
myeloid cell differentiation GO:0030099 233 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
negative regulation of nervous system development GO:0051961 156 0.013
negative regulation of immune system process GO:0002683 209 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
dephosphorylation GO:0016311 129 0.013
small molecule catabolic process GO:0044282 71 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
early endosome to late endosome transport GO:0045022 2 0.012
regulation of protein localization GO:0032880 231 0.012
Mouse
carboxylic acid biosynthetic process GO:0046394 86 0.012
intracellular mrna localization GO:0008298 4 0.012
regulation of ion transport GO:0043269 215 0.012
Mouse
mesenchymal cell differentiation GO:0048762 107 0.012
carbohydrate metabolic process GO:0005975 230 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
proteasome assembly GO:0043248 1 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
negative regulation of synaptic vesicle transport GO:1902804 3 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
nucleoside biosynthetic process GO:0009163 21 0.012
amide transport GO:0042886 138 0.012
Mouse
vesicle localization GO:0051648 86 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
regulation of membrane potential GO:0042391 192 0.012
negative regulation of cell development GO:0010721 169 0.012
regulation of neuron projection development GO:0010975 169 0.012
oocyte construction GO:0007308 2 0.012
organic acid catabolic process GO:0016054 51 0.012
tissue migration GO:0090130 68 0.012
ribonucleotide biosynthetic process GO:0009260 59 0.012
regulation of cytokine production GO:0001817 266 0.012
nucleobase biosynthetic process GO:0046112 3 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
regulation of erbb signaling pathway GO:1901184 16 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
positive regulation of cell adhesion GO:0045785 80 0.011
positive regulation of growth GO:0045927 104 0.011
positive regulation of endopeptidase activity GO:0010950 43 0.011
multi multicellular organism process GO:0044706 109 0.011
developmental maturation GO:0021700 193 0.011
aromatic compound catabolic process GO:0019439 286 0.011
proteasomal ubiquitin independent protein catabolic process GO:0010499 1 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.011
monocarboxylic acid catabolic process GO:0072329 27 0.011
response to acid chemical GO:0001101 111 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
positive regulation of atpase activity GO:0032781 3 0.011
phospholipid metabolic process GO:0006644 87 0.011
protein homooligomerization GO:0051260 43 0.011
synaptic vesicle transport GO:0048489 57 0.011
negative regulation of erbb signaling pathway GO:1901185 7 0.011
adherens junction maintenance GO:0034334 1 0.011
lipid catabolic process GO:0016042 69 0.011
skeletal system development GO:0001501 356 0.011
organic anion transport GO:0015711 137 0.011
rhythmic process GO:0048511 174 0.011
forebrain development GO:0030900 302 0.011
transcription factor import into nucleus GO:0042991 26 0.011
Mouse
synaptic vesicle localization GO:0097479 59 0.010
immune effector process GO:0002252 321 0.010
regulation of peptidase activity GO:0052547 96 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010
regulation of transporter activity GO:0032409 57 0.010
peptide transport GO:0015833 133 0.010
Mouse
regulation of epidermal growth factor receptor signaling pathway GO:0042058 13 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
regulation of circadian sleep wake cycle GO:0042749 3 0.010
ossification GO:0001503 216 0.010
regulation of response to dna damage stimulus GO:2001020 34 0.010

Pdcd6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.035
inherited metabolic disorder DOID:655 0 0.035
epilepsy syndrome DOID:1826 0 0.022
central nervous system disease DOID:331 0 0.022
brain disease DOID:936 0 0.022
electroclinical syndrome DOID:0050701 0 0.022
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010