Mus musculus

46 known processes

P2ry12

purinergic receptor P2Y, G-protein coupled 12

(Aliases: 2900079B22Rik,P2Y12,4921504D23Rik)

P2ry12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.630
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 1 0.482
cytokine production GO:0001816 319 0.194
g protein coupled receptor signaling pathway GO:0007186 243 0.181
blood coagulation GO:0007596 76 0.172
cation transport GO:0006812 399 0.147
Rat
activation of immune response GO:0002253 138 0.146
hemostasis GO:0007599 78 0.143
regulation of cytokine production GO:0001817 266 0.137
coagulation GO:0050817 78 0.131
cellular lipid metabolic process GO:0044255 323 0.116
regulation of defense response GO:0031347 233 0.112
regulation of cell activation GO:0050865 289 0.107
immune response regulating signaling pathway GO:0002764 125 0.104
inflammatory response GO:0006954 244 0.104
detection of yeast GO:0001879 2 0.090
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.090
negative regulation of phosphate metabolic process GO:0045936 184 0.090
ras protein signal transduction GO:0007265 77 0.089
amine metabolic process GO:0009308 45 0.089
cell adhesion GO:0007155 329 0.088
Human Rat
cellular ketone metabolic process GO:0042180 84 0.088
cellular response to lipopolysaccharide GO:0071222 77 0.088
myeloid cell differentiation GO:0030099 233 0.086
nucleoside catabolic process GO:0009164 206 0.084
positive regulation of cytokine production GO:0001819 174 0.082
small gtpase mediated signal transduction GO:0007264 97 0.082
cellular response to molecule of bacterial origin GO:0071219 83 0.080
wound healing GO:0042060 157 0.076
regulation of secretion by cell GO:1903530 249 0.076
Rat
regulation of lymphocyte activation GO:0051249 240 0.074
immune effector process GO:0002252 321 0.074
mapk cascade GO:0000165 281 0.074
purinergic receptor signaling pathway GO:0035587 7 0.072
regulation of mast cell activation GO:0033003 21 0.068
regulation of inflammatory response GO:0050727 147 0.067
endocytosis GO:0006897 168 0.065
regulation of transferase activity GO:0051338 263 0.065
reactive oxygen species biosynthetic process GO:1903409 8 0.063
regulation of mapk cascade GO:0043408 248 0.062
negative regulation of phosphorus metabolic process GO:0010563 184 0.061
regulation of protein localization GO:0032880 231 0.061
gtp metabolic process GO:0046039 144 0.061
circulatory system process GO:0003013 197 0.061
regulation of leukocyte mediated immunity GO:0002703 104 0.060
regulation of cellular ketone metabolic process GO:0010565 66 0.060
hematopoietic progenitor cell differentiation GO:0002244 143 0.060
ion transmembrane transport GO:0034220 361 0.059
Rat
negative regulation of cell proliferation GO:0008285 296 0.059
cellular amino acid metabolic process GO:0006520 103 0.059
response to lipopolysaccharide GO:0032496 128 0.059
blood circulation GO:0008015 195 0.059
multicellular organismal signaling GO:0035637 91 0.058
negative regulation of protein metabolic process GO:0051248 282 0.057
reactive oxygen species metabolic process GO:0072593 84 0.057
cellular response to biotic stimulus GO:0071216 92 0.057
membrane organization GO:0061024 245 0.057
negative regulation of serotonin secretion GO:0014063 2 0.056
regulation of response to wounding GO:1903034 189 0.055
nitrogen compound transport GO:0071705 271 0.055
Rat
t cell activation GO:0042110 289 0.055
ribonucleoside metabolic process GO:0009119 245 0.054
chemotaxis GO:0006935 247 0.054
transmembrane transport GO:0055085 412 0.054
Rat
response to molecule of bacterial origin GO:0002237 143 0.053
regulation of protein transport GO:0051223 163 0.052
gtp catabolic process GO:0006184 143 0.052
regulation of system process GO:0044057 200 0.052
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.052
regulation of secretion GO:0051046 274 0.051
Rat
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.051
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.051
regulation of kinase activity GO:0043549 249 0.051
glycosyl compound catabolic process GO:1901658 206 0.051
cation homeostasis GO:0055080 212 0.050
cellular homeostasis GO:0019725 240 0.050
cellular chemical homeostasis GO:0055082 215 0.050
detection of fungus GO:0016046 2 0.050
cellular response to organonitrogen compound GO:0071417 145 0.050
divalent inorganic cation transport GO:0072511 178 0.050
Rat
regulation of protein serine threonine kinase activity GO:0071900 157 0.050
purine ribonucleoside metabolic process GO:0046128 241 0.049
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.049
axonogenesis GO:0007409 274 0.048
positive regulation of immune effector process GO:0002699 107 0.048
ribonucleotide metabolic process GO:0009259 291 0.047
negative regulation of intracellular signal transduction GO:1902532 167 0.047
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.047
negative regulation of immune system process GO:0002683 209 0.046
ribonucleoside triphosphate catabolic process GO:0009203 199 0.046
immune response activating signal transduction GO:0002757 116 0.046
regulation of anatomical structure size GO:0090066 178 0.046
regulation of protein kinase activity GO:0045859 232 0.046
rho protein signal transduction GO:0007266 32 0.046
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.046
regulation of cellular amine metabolic process GO:0033238 20 0.045
purine ribonucleotide metabolic process GO:0009150 290 0.045
regulation of ion transport GO:0043269 215 0.045
organonitrogen compound catabolic process GO:1901565 264 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.044
positive regulation of innate immune response GO:0045089 80 0.044
organic cyclic compound catabolic process GO:1901361 295 0.044
reactive nitrogen species metabolic process GO:2001057 0 0.043
regulation of map kinase activity GO:0043405 120 0.043
positive regulation of cellular amine metabolic process GO:0033240 5 0.043
lipid biosynthetic process GO:0008610 179 0.043
ribonucleotide catabolic process GO:0009261 208 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.042
protein secretion GO:0009306 111 0.042
nucleobase containing small molecule metabolic process GO:0055086 352 0.042
cellular amine metabolic process GO:0044106 44 0.042
glycerophospholipid metabolic process GO:0006650 71 0.042
negative regulation of protein modification process GO:0031400 163 0.042
carbohydrate derivative catabolic process GO:1901136 231 0.042
cognition GO:0050890 149 0.042
regulation of cellular catabolic process GO:0031329 242 0.041
neuronal action potential GO:0019228 54 0.041
positive regulation of ion transport GO:0043270 65 0.041
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.041
purine nucleoside metabolic process GO:0042278 241 0.040
purine nucleoside catabolic process GO:0006152 205 0.040
metal ion homeostasis GO:0055065 189 0.040
anatomical structure homeostasis GO:0060249 145 0.040
sequestering of metal ion GO:0051238 19 0.040
negative regulation of cell activation GO:0050866 111 0.040
activation of innate immune response GO:0002218 56 0.040
cation transmembrane transport GO:0098655 266 0.040
Rat
exocytosis GO:0006887 121 0.039
single organism cell adhesion GO:0098602 156 0.039
Human Rat
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.039
single organismal cell cell adhesion GO:0016337 131 0.039
Human Rat
glycosyl compound metabolic process GO:1901657 246 0.039
aromatic compound catabolic process GO:0019439 286 0.039
purine containing compound metabolic process GO:0072521 311 0.038
regulation of body fluid levels GO:0050878 162 0.038
oxidation reduction process GO:0055114 342 0.038
monocarboxylic acid metabolic process GO:0032787 191 0.037
phospholipid metabolic process GO:0006644 87 0.037
regulation of homeostatic process GO:0032844 182 0.037
ribose phosphate metabolic process GO:0019693 291 0.037
positive regulation of secretion GO:0051047 130 0.037
tissue homeostasis GO:0001894 115 0.036
calcium ion transport into cytosol GO:0060402 48 0.036
nucleotide metabolic process GO:0009117 332 0.036
purine nucleotide metabolic process GO:0006163 302 0.036
second messenger mediated signaling GO:0019932 73 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.036
purine nucleotide catabolic process GO:0006195 211 0.035
small molecule biosynthetic process GO:0044283 132 0.035
negative regulation of phospholipase activity GO:0010519 4 0.035
regulation of organelle organization GO:0033043 289 0.035
transmission of nerve impulse GO:0019226 76 0.035
divalent metal ion transport GO:0070838 172 0.035
Rat
monocyte extravasation GO:0035696 2 0.035
nucleoside metabolic process GO:0009116 246 0.035
organic hydroxy compound transport GO:0015850 93 0.035
Rat
purine ribonucleoside catabolic process GO:0046130 205 0.034
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
cytokine metabolic process GO:0042107 71 0.034
leukocyte activation involved in immune response GO:0002366 126 0.034
phagocytosis GO:0006909 66 0.034
action potential GO:0001508 78 0.034
cytokine secretion GO:0050663 72 0.034
inorganic ion transmembrane transport GO:0098660 234 0.034
Rat
response to growth factor GO:0070848 198 0.034
cell activation involved in immune response GO:0002263 126 0.033
purine ribonucleotide catabolic process GO:0009154 208 0.033
innate immune response GO:0045087 157 0.033
organophosphate catabolic process GO:0046434 232 0.033
negative regulation of phosphorylation GO:0042326 166 0.033
regulation of cell motility GO:2000145 236 0.032
muscle cell differentiation GO:0042692 261 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
ribonucleoside triphosphate metabolic process GO:0009199 220 0.032
guanosine containing compound metabolic process GO:1901068 144 0.032
leukocyte mediated cytotoxicity GO:0001909 62 0.032
positive regulation of cell activation GO:0050867 158 0.032
thrombin receptor signaling pathway GO:0070493 2 0.031
regulation of establishment of protein localization GO:0070201 181 0.031
microglia differentiation GO:0014004 2 0.031
negative regulation of cellular component organization GO:0051129 194 0.031
cytoplasmic transport GO:0016482 234 0.031
natural killer cell activation GO:0030101 44 0.030
actin filament organization GO:0007015 113 0.030
sensory perception GO:0007600 245 0.030
glycerolipid metabolic process GO:0046486 122 0.030
renal system development GO:0072001 225 0.030
regulation of nucleotide metabolic process GO:0006140 169 0.029
cellular calcium ion homeostasis GO:0006874 119 0.029
carbohydrate homeostasis GO:0033500 128 0.029
i kappab kinase nf kappab signaling GO:0007249 85 0.029
multicellular organismal homeostasis GO:0048871 164 0.029
cellular ion homeostasis GO:0006873 165 0.029
divalent inorganic cation homeostasis GO:0072507 138 0.029
positive regulation of endocytosis GO:0045807 42 0.029
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
phosphatidylinositol metabolic process GO:0046488 45 0.029
negative regulation of mapk cascade GO:0043409 65 0.029
negative regulation of protein phosphorylation GO:0001933 126 0.029
carbohydrate metabolic process GO:0005975 230 0.029
regulation of vesicle mediated transport GO:0060627 139 0.028
pattern recognition receptor signaling pathway GO:0002221 47 0.028
regulation of tumor necrosis factor production GO:0032680 49 0.028
regulation of phagocytosis GO:0050764 33 0.028
leukocyte migration GO:0050900 124 0.028
regulation of purine nucleotide catabolic process GO:0033121 122 0.028
blood vessel morphogenesis GO:0048514 285 0.028
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.028
regulation of membrane potential GO:0042391 192 0.028
glucose homeostasis GO:0042593 128 0.028
muscle system process GO:0003012 141 0.028
fatty acid metabolic process GO:0006631 121 0.028
positive regulation of mapk cascade GO:0043410 170 0.027
negative regulation of phagocytosis GO:0050765 4 0.027
cell recognition GO:0008037 83 0.027
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.027
leukocyte mediated immunity GO:0002443 174 0.027
protein modification by small protein conjugation GO:0032446 187 0.027
cellular response to lipid GO:0071396 145 0.026
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.026
regulation of nucleotide catabolic process GO:0030811 122 0.026
regulation of protein secretion GO:0050708 82 0.026
kidney development GO:0001822 213 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
learning or memory GO:0007611 148 0.026
myeloid leukocyte activation GO:0002274 83 0.026
regulation of reactive oxygen species metabolic process GO:2000377 40 0.026
cellular metal ion homeostasis GO:0006875 151 0.026
regulation of metal ion transport GO:0010959 106 0.026
Rat
nucleoside triphosphate metabolic process GO:0009141 230 0.026
positive regulation of dna biosynthetic process GO:2000573 4 0.026
regulation of cell migration GO:0030334 219 0.026
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.025
regulation of hormone levels GO:0010817 211 0.025
toll like receptor signaling pathway GO:0002224 38 0.025
organelle localization GO:0051640 179 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
cellular carbohydrate metabolic process GO:0044262 119 0.025
sequestering of calcium ion GO:0051208 18 0.025
positive regulation of secretion by cell GO:1903532 114 0.025
muscle contraction GO:0006936 101 0.025
calcium mediated signaling GO:0019722 46 0.025
erk1 and erk2 cascade GO:0070371 77 0.025
detection of stimulus GO:0051606 84 0.025
regulation of endocytosis GO:0030100 69 0.025
positive regulation of defense response GO:0031349 124 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
response to organonitrogen compound GO:0010243 246 0.024
maintenance of location GO:0051235 89 0.024
heterocycle catabolic process GO:0046700 280 0.024
cellular divalent inorganic cation homeostasis GO:0072503 127 0.024
regulation of hydrolase activity GO:0051336 246 0.024
positive regulation of cytokine secretion GO:0050715 41 0.024
peptidyl amino acid modification GO:0018193 336 0.024
synapse organization GO:0050808 125 0.024
positive regulation of protein modification process GO:0031401 299 0.024
regulation of rho protein signal transduction GO:0035023 71 0.024
regulation of ras protein signal transduction GO:0046578 114 0.024
cytosolic calcium ion homeostasis GO:0051480 70 0.024
negative regulation of map kinase activity GO:0043407 34 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.023
cell chemotaxis GO:0060326 81 0.023
nucleotide catabolic process GO:0009166 217 0.023
positive regulation of leukocyte mediated immunity GO:0002705 70 0.023
glial cell differentiation GO:0010001 131 0.023
positive regulation of transferase activity GO:0051347 167 0.023
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
leukocyte differentiation GO:0002521 342 0.022
regulation of t cell proliferation GO:0042129 92 0.022
positive regulation of nucleotide catabolic process GO:0030813 88 0.022
defense response to other organism GO:0098542 197 0.022
inorganic cation transmembrane transport GO:0098662 207 0.022
Rat
bone resorption GO:0045453 38 0.022
response to peptide GO:1901652 136 0.022
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.022
intestinal epithelial structure maintenance GO:0060729 4 0.022
anion transport GO:0006820 177 0.022
homeostasis of number of cells GO:0048872 210 0.022
angiogenesis GO:0001525 201 0.022
regulation of lymphocyte mediated immunity GO:0002706 84 0.021
calcium ion transport GO:0006816 159 0.021
Rat
guanosine containing compound catabolic process GO:1901069 144 0.021
cellular response to peptide GO:1901653 92 0.021
regulation of natural killer cell mediated immunity GO:0002715 19 0.021
synaptic transmission GO:0007268 329 0.021
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.021
organic acid biosynthetic process GO:0016053 86 0.021
lymphocyte proliferation GO:0046651 164 0.021
negative regulation of molecular function GO:0044092 258 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.021
wnt signaling pathway GO:0016055 188 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
purine containing compound catabolic process GO:0072523 213 0.020
negative regulation of response to wounding GO:1903035 77 0.020
calcium ion homeostasis GO:0055074 127 0.020
regulation of blood pressure GO:0008217 93 0.020
positive regulation of phagocytosis GO:0050766 26 0.020
positive regulation of homeostatic process GO:0032846 64 0.020
positive regulation of protein transport GO:0051222 93 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
response to peptide hormone GO:0043434 127 0.020
carboxylic acid biosynthetic process GO:0046394 86 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
mast cell activation GO:0045576 27 0.019
positive regulation of nervous system development GO:0051962 221 0.019
regulation of erk1 and erk2 cascade GO:0070372 71 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.019
regulation of intracellular transport GO:0032386 159 0.019
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.019
myelination GO:0042552 74 0.019
monocarboxylic acid biosynthetic process GO:0072330 61 0.019
negative regulation of leukocyte mediated immunity GO:0002704 29 0.019
regulation of serotonin secretion GO:0014062 3 0.019
regulation of cytokine secretion GO:0050707 61 0.019
negative regulation of mast cell degranulation GO:0043305 4 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
apoptotic signaling pathway GO:0097190 306 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
response to organic cyclic compound GO:0014070 198 0.019
forebrain development GO:0030900 302 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.019
regulation of interferon gamma production GO:0032649 57 0.019
alcohol metabolic process GO:0006066 116 0.018
microtubule based process GO:0007017 236 0.018
positive regulation of cell development GO:0010720 237 0.018
platelet activation GO:0030168 40 0.018
intracellular protein transport GO:0006886 204 0.018
response to oxidative stress GO:0006979 123 0.018
regulation of tube size GO:0035150 57 0.018
response to extracellular stimulus GO:0009991 127 0.018
positive regulation of tumor necrosis factor production GO:0032760 30 0.018
negative regulation of inflammatory response GO:0050728 61 0.018
stress activated mapk cascade GO:0051403 80 0.018
rhodopsin mediated signaling pathway GO:0016056 4 0.018
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.018
endomembrane system organization GO:0010256 147 0.018
dephosphorylation GO:0016311 129 0.018
regulation of leukocyte proliferation GO:0070663 121 0.018
regulation of lymphocyte proliferation GO:0050670 117 0.018
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.018
actin cytoskeleton organization GO:0030036 220 0.018
cell junction organization GO:0034330 77 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.018
cell cell adhesion GO:0098609 41 0.018
regulation of cellular component size GO:0032535 121 0.018
negative regulation of immune effector process GO:0002698 55 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
regulation of blood vessel size GO:0050880 56 0.017
protein ubiquitination GO:0016567 171 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
positive regulation of gtpase activity GO:0043547 85 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.017
adaptive immune response GO:0002250 155 0.017
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.017
microglia development GO:0014005 2 0.017
cell killing GO:0001906 67 0.017
positive regulation of gtp catabolic process GO:0033126 85 0.017
cellular response to peptide hormone stimulus GO:0071375 92 0.017
positive regulation of protein secretion GO:0050714 52 0.017
positive regulation of response to wounding GO:1903036 66 0.017
regulation of b cell activation GO:0050864 81 0.017
leukocyte proliferation GO:0070661 172 0.017
negative regulation of transferase activity GO:0051348 85 0.017
regulation of transmembrane transport GO:0034762 128 0.017
stem cell proliferation GO:0072089 117 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
carbohydrate biosynthetic process GO:0016051 74 0.017
positive regulation of intracellular transport GO:0032388 70 0.017
regulation of ion transmembrane transport GO:0034765 119 0.016
regulation of monocyte chemotaxis GO:0090025 3 0.016
phosphatidylinositol mediated signaling GO:0048015 41 0.016
sensory organ morphogenesis GO:0090596 242 0.016
positive regulation of leukocyte proliferation GO:0070665 73 0.016
peptidyl tyrosine modification GO:0018212 145 0.016
ensheathment of neurons GO:0007272 76 0.016
developmental cell growth GO:0048588 84 0.016
regulation of blood coagulation GO:0030193 28 0.016
regulation of gtp catabolic process GO:0033124 113 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
positive regulation of cell migration GO:0030335 109 0.016
mitotic cell cycle GO:0000278 195 0.016
nitric oxide biosynthetic process GO:0006809 25 0.016
response to drug GO:0042493 75 0.016
regulation of vasculature development GO:1901342 88 0.016
vascular process in circulatory system GO:0003018 62 0.016
skeletal system development GO:0001501 356 0.016
learning GO:0007612 98 0.016
protein localization to organelle GO:0033365 185 0.016
cell substrate adhesion GO:0031589 130 0.016
nuclear division GO:0000280 158 0.016
interleukin 6 production GO:0032635 58 0.016
regulation of tissue remodeling GO:0034103 38 0.016
neuron projection guidance GO:0097485 141 0.016
activation of mapk activity GO:0000187 59 0.016
interferon gamma production GO:0032609 67 0.016
canonical wnt signaling pathway GO:0060070 130 0.015
cytokine biosynthetic process GO:0042089 68 0.015
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.015
regulation of cell cycle GO:0051726 281 0.015
placenta development GO:0001890 140 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
positive regulation of cell killing GO:0031343 33 0.015
mast cell mediated immunity GO:0002448 20 0.015
axon guidance GO:0007411 141 0.015
organelle fission GO:0048285 170 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
myeloid leukocyte mediated immunity GO:0002444 42 0.015
positive regulation of organelle organization GO:0010638 128 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
heart process GO:0003015 94 0.015
toll like receptor 9 signaling pathway GO:0034162 6 0.015
regulation of cell cycle process GO:0010564 160 0.015
protein kinase b signaling GO:0043491 74 0.015
Rat
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.015
protein localization to membrane GO:0072657 108 0.015
response to insulin GO:0032868 100 0.015
dna metabolic process GO:0006259 303 0.015
regulation of cytokine biosynthetic process GO:0042035 59 0.015
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
bone remodeling GO:0046849 53 0.015
membrane lipid metabolic process GO:0006643 53 0.015
negative regulation of secretion GO:0051048 61 0.015
Rat
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.015
lipid catabolic process GO:0016042 69 0.015
sensory perception of mechanical stimulus GO:0050954 107 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
positive regulation of monocyte chemotaxis GO:0090026 2 0.014
hindbrain development GO:0030902 128 0.014
toll like receptor 7 signaling pathway GO:0034154 4 0.014
protein processing GO:0016485 163 0.014
response to defense related nitric oxide production by other organism involved in symbiotic interaction GO:0052551 2 0.014
fat cell differentiation GO:0045444 160 0.014
glucose transport GO:0015758 56 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
plasma membrane organization GO:0007009 90 0.014
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.014
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.014
regulation of actin cytoskeleton organization GO:0032956 84 0.014
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.014
regulation of immunological synapse formation GO:2000520 2 0.014
monosaccharide transport GO:0015749 58 0.014
synapse assembly GO:0007416 56 0.014
innate immune response activating signal transduction GO:0002758 50 0.014
regulation of ion homeostasis GO:2000021 64 0.014
ossification GO:0001503 216 0.014
negative regulation of defense response GO:0031348 77 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
release of sequestered calcium ion into cytosol GO:0051209 42 0.014
positive regulation of map kinase activity GO:0043406 84 0.014
lipid modification GO:0030258 65 0.014
t cell proliferation GO:0042098 120 0.014
oligodendrocyte differentiation GO:0048709 53 0.014
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.014
neuron migration GO:0001764 122 0.014
regulation of calcium ion transport into cytosol GO:0010522 31 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
smooth muscle cell chemotaxis GO:0071670 2 0.014
protein maturation GO:0051604 176 0.014
axon ensheathment GO:0008366 76 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.014
response to radiation GO:0009314 165 0.013
cell junction maintenance GO:0034331 4 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
sphingolipid metabolic process GO:0006665 45 0.013
serotonin secretion involved in inflammatory response GO:0002442 4 0.013
carboxylic acid transport GO:0046942 100 0.013
regulation of cell projection organization GO:0031344 206 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
memory GO:0007613 58 0.013
small molecule catabolic process GO:0044282 71 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
signal transduction in absence of ligand GO:0038034 55 0.013
regulation of coagulation GO:0050818 31 0.013
positive regulation of kinase activity GO:0033674 155 0.013
positive regulation of calcium mediated signaling GO:0050850 15 0.013
male gamete generation GO:0048232 285 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
microglial cell activation GO:0001774 3 0.013
lipoprotein metabolic process GO:0042157 43 0.013

P2ry12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035
immune system disease DOID:2914 0 0.035
musculoskeletal system disease DOID:17 0 0.030
connective tissue disease DOID:65 0 0.030
sensory system disease DOID:0050155 0 0.020
disease by infectious agent DOID:0050117 0 0.019
disease of metabolism DOID:0014667 0 0.018
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013