Mus musculus

0 known processes

Megf6

multiple EGF-like-domains 6

(Aliases: MGC49785,2600001P17Rik,Egfl3)

Megf6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small gtpase mediated signal transduction GO:0007264 97 0.106
negative regulation of cellular component organization GO:0051129 194 0.092
amine metabolic process GO:0009308 45 0.079
regulation of neuron differentiation GO:0045664 281 0.077
Mouse
regulation of organelle organization GO:0033043 289 0.076
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.073
regulation of cellular amine metabolic process GO:0033238 20 0.064
positive regulation of cellular amine metabolic process GO:0033240 5 0.063
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.061
regulation of cellular ketone metabolic process GO:0010565 66 0.058
camera type eye development GO:0043010 266 0.055
Mouse
wnt signaling pathway GO:0016055 188 0.055
rho protein signal transduction GO:0007266 32 0.054
purine nucleoside triphosphate metabolic process GO:0009144 226 0.053
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.053
organic cyclic compound catabolic process GO:1901361 295 0.052
sensory organ morphogenesis GO:0090596 242 0.052
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
negative regulation of neuron projection development GO:0010977 50 0.051
nucleobase containing small molecule metabolic process GO:0055086 352 0.050
cellular amino acid metabolic process GO:0006520 103 0.050
cellular amine metabolic process GO:0044106 44 0.050
positive regulation of cell development GO:0010720 237 0.050
Mouse
cell adhesion GO:0007155 329 0.050
Mouse
ribose phosphate metabolic process GO:0019693 291 0.048
cellular ketone metabolic process GO:0042180 84 0.048
gtp catabolic process GO:0006184 143 0.047
ossification GO:0001503 216 0.047
nucleotide metabolic process GO:0009117 332 0.047
single organism cell adhesion GO:0098602 156 0.047
Mouse
ribonucleoside metabolic process GO:0009119 245 0.045
muscle tissue development GO:0060537 308 0.044
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.043
purine nucleoside triphosphate catabolic process GO:0009146 203 0.041
ribonucleoside triphosphate metabolic process GO:0009199 220 0.041
actin cytoskeleton organization GO:0030036 220 0.040
regulation of cell migration GO:0030334 219 0.040
regeneration GO:0031099 38 0.040
Mouse
negative regulation of nervous system development GO:0051961 156 0.040
forebrain development GO:0030900 302 0.040
apoptotic signaling pathway GO:0097190 306 0.039
ribonucleoside triphosphate catabolic process GO:0009203 199 0.039
guanosine containing compound catabolic process GO:1901069 144 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.039
retina development in camera type eye GO:0060041 119 0.039
Mouse
positive regulation of organelle organization GO:0010638 128 0.039
sensory perception GO:0007600 245 0.038
negative regulation of cell development GO:0010721 169 0.037
carbohydrate derivative catabolic process GO:1901136 231 0.036
developmental maturation GO:0021700 193 0.036
Mouse
purine containing compound metabolic process GO:0072521 311 0.036
organonitrogen compound catabolic process GO:1901565 264 0.036
chemotaxis GO:0006935 247 0.036
nucleoside phosphate catabolic process GO:1901292 222 0.036
ras protein signal transduction GO:0007265 77 0.036
nucleoside metabolic process GO:0009116 246 0.036
regulation of cell projection organization GO:0031344 206 0.035
Mouse
neuron apoptotic process GO:0051402 142 0.035
immune effector process GO:0002252 321 0.034
stem cell development GO:0048864 219 0.034
epithelial tube morphogenesis GO:0060562 303 0.034
extracellular matrix organization GO:0030198 147 0.034
regulation of secretion by cell GO:1903530 249 0.033
kidney epithelium development GO:0072073 121 0.033
positive regulation of gtp catabolic process GO:0033126 85 0.033
purine nucleoside catabolic process GO:0006152 205 0.033
nucleoside triphosphate metabolic process GO:0009141 230 0.032
nucleotide catabolic process GO:0009166 217 0.032
organophosphate catabolic process GO:0046434 232 0.032
muscle cell differentiation GO:0042692 261 0.032
glycosyl compound metabolic process GO:1901657 246 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
regulation of protein localization GO:0032880 231 0.031
cellular nitrogen compound catabolic process GO:0044270 280 0.031
extracellular structure organization GO:0043062 148 0.030
regulation of nucleoside metabolic process GO:0009118 130 0.030
positive regulation of gtpase activity GO:0043547 85 0.030
negative regulation of cell proliferation GO:0008285 296 0.030
connective tissue development GO:0061448 179 0.030
positive regulation of cellular catabolic process GO:0031331 148 0.030
membrane organization GO:0061024 245 0.030
regulation of neuron death GO:1901214 134 0.030
myotube differentiation GO:0014902 105 0.030
regulation of cell adhesion GO:0030155 154 0.030
purine nucleotide catabolic process GO:0006195 211 0.029
regulation of gtp catabolic process GO:0033124 113 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
cell type specific apoptotic process GO:0097285 268 0.029
purine ribonucleoside catabolic process GO:0046130 205 0.029
positive regulation of hydrolase activity GO:0051345 148 0.029
ribonucleoside catabolic process GO:0042454 206 0.028
purine nucleotide metabolic process GO:0006163 302 0.028
regulation of establishment of protein localization GO:0070201 181 0.028
cell substrate adhesion GO:0031589 130 0.028
developmental cell growth GO:0048588 84 0.028
purine ribonucleoside metabolic process GO:0046128 241 0.028
nuclear division GO:0000280 158 0.028
negative regulation of synapse assembly GO:0051964 3 0.028
positive regulation of cell adhesion GO:0045785 80 0.027
stem cell differentiation GO:0048863 268 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
positive regulation of protein kinase activity GO:0045860 144 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.026
regulation of cellular response to growth factor stimulus GO:0090287 82 0.026
morphogenesis of embryonic epithelium GO:0016331 159 0.026
fat cell differentiation GO:0045444 160 0.026
regulation of ossification GO:0030278 112 0.026
skeletal system morphogenesis GO:0048705 203 0.026
regulation of ras gtpase activity GO:0032318 88 0.026
cellular response to organonitrogen compound GO:0071417 145 0.025
positive regulation of ras gtpase activity GO:0032320 65 0.025
neuron death GO:0070997 154 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.025
regulation of ras protein signal transduction GO:0046578 114 0.025
negative regulation of protein modification process GO:0031400 163 0.024
organelle localization GO:0051640 179 0.024
macromolecule catabolic process GO:0009057 281 0.024
mapk cascade GO:0000165 281 0.024
nucleoside catabolic process GO:0009164 206 0.024
regulation of cell motility GO:2000145 236 0.024
negative regulation of cell projection organization GO:0031345 56 0.024
positive regulation of nucleotide metabolic process GO:0045981 114 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
purine containing compound catabolic process GO:0072523 213 0.023
ribonucleotide catabolic process GO:0009261 208 0.023
axonogenesis GO:0007409 274 0.023
regionalization GO:0003002 337 0.023
regulation of nucleotide catabolic process GO:0030811 122 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
lateral inhibition GO:0046331 1 0.023
tube formation GO:0035148 140 0.023
regulation of transferase activity GO:0051338 263 0.023
regulation of cellular catabolic process GO:0031329 242 0.023
positive regulation of transferase activity GO:0051347 167 0.023
cytokine production GO:0001816 319 0.022
striated muscle tissue development GO:0014706 293 0.022
Mouse
intracellular protein transport GO:0006886 204 0.022
inflammatory response GO:0006954 244 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
epithelial tube formation GO:0072175 130 0.022
positive regulation of nucleotide catabolic process GO:0030813 88 0.022
regulation of mapk cascade GO:0043408 248 0.022
regulation of anatomical structure size GO:0090066 178 0.022
heterocycle catabolic process GO:0046700 280 0.022
organelle fission GO:0048285 170 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.022
protein catabolic process GO:0030163 221 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.022
male gamete generation GO:0048232 285 0.021
regulation of neuron projection development GO:0010975 169 0.021
Mouse
cell growth GO:0016049 130 0.021
oxidation reduction process GO:0055114 342 0.021
aromatic compound catabolic process GO:0019439 286 0.021
myeloid cell differentiation GO:0030099 233 0.021
positive regulation of mapk cascade GO:0043410 170 0.021
gtp metabolic process GO:0046039 144 0.021
cellular lipid metabolic process GO:0044255 323 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
cation transmembrane transport GO:0098655 266 0.021
regulation of response to wounding GO:1903034 189 0.021
Mouse
ear development GO:0043583 200 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
cellular response to hormone stimulus GO:0032870 150 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
Mouse
ribonucleotide metabolic process GO:0009259 291 0.020
interleukin 8 secretion GO:0072606 3 0.020
single organismal cell cell adhesion GO:0016337 131 0.020
Mouse
telencephalon development GO:0021537 186 0.020
regulation of rho gtpase activity GO:0032319 58 0.020
negative regulation of molecular function GO:0044092 258 0.020
dendrite development GO:0016358 115 0.020
Mouse
synaptic transmission GO:0007268 329 0.020
pallium development GO:0021543 120 0.020
peptidyl amino acid modification GO:0018193 336 0.019
gland development GO:0048732 330 0.019
regulation of secretion GO:0051046 274 0.019
g protein coupled receptor signaling pathway GO:0007186 243 0.019
histone modification GO:0016570 159 0.019
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
regulation of cellular component size GO:0032535 121 0.019
regulation of kinase activity GO:0043549 249 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
limb development GO:0060173 166 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
mesonephric epithelium development GO:0072163 94 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
developmental growth involved in morphogenesis GO:0060560 138 0.018
positive regulation of nervous system development GO:0051962 221 0.018
Mouse
transmembrane transport GO:0055085 412 0.018
skeletal muscle cell differentiation GO:0035914 66 0.018
Mouse
primary neural tube formation GO:0014020 95 0.018
protein processing GO:0016485 163 0.018
interleukin 8 production GO:0032637 4 0.018
peptidyl tyrosine modification GO:0018212 145 0.018
protein ubiquitination GO:0016567 171 0.018
regulation of hydrolase activity GO:0051336 246 0.017
embryonic epithelial tube formation GO:0001838 130 0.017
microtubule based process GO:0007017 236 0.017
cytoplasmic transport GO:0016482 234 0.017
carbohydrate homeostasis GO:0033500 128 0.017
regulation of interleukin 8 production GO:0032677 3 0.017
blood vessel morphogenesis GO:0048514 285 0.017
phospholipid metabolic process GO:0006644 87 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
germ cell development GO:0007281 185 0.017
respiratory system development GO:0060541 190 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
leukocyte differentiation GO:0002521 342 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
neural tube development GO:0021915 160 0.017
appendage morphogenesis GO:0035107 149 0.017
regulation of neuron apoptotic process GO:0043523 122 0.017
tube closure GO:0060606 91 0.017
regulation of cell growth GO:0001558 91 0.017
regulation of cell size GO:0008361 72 0.017
protein localization to organelle GO:0033365 185 0.016
epithelial cell proliferation GO:0050673 174 0.016
response to growth factor GO:0070848 198 0.016
neural tube closure GO:0001843 90 0.016
covalent chromatin modification GO:0016569 163 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
wound healing GO:0042060 157 0.016
positive regulation of protein modification process GO:0031401 299 0.016
meiotic cell cycle GO:0051321 122 0.016
t cell activation GO:0042110 289 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
skeletal system development GO:0001501 356 0.016
positive regulation of kinase activity GO:0033674 155 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
gliogenesis GO:0042063 141 0.016
canonical wnt signaling pathway GO:0060070 130 0.016
cardiac chamber development GO:0003205 108 0.016
regulation of cytoskeleton organization GO:0051493 122 0.015
regulation of inflammatory response GO:0050727 147 0.015
lymphocyte differentiation GO:0030098 242 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
meiotic nuclear division GO:0007126 115 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
regulation of system process GO:0044057 200 0.015
cellular chemical homeostasis GO:0055082 215 0.015
positive regulation of rho gtpase activity GO:0032321 41 0.015
positive regulation of nucleoside metabolic process GO:0045979 91 0.015
microtubule cytoskeleton organization GO:0000226 157 0.015
metencephalon development GO:0022037 89 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
regulation of axon extension GO:0030516 43 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
embryonic appendage morphogenesis GO:0035113 126 0.015
urogenital system development GO:0001655 261 0.015
regulation of rho protein signal transduction GO:0035023 71 0.015
cation transport GO:0006812 399 0.015
regulation of actin filament based process GO:0032970 99 0.015
lung development GO:0030324 164 0.015
synapse organization GO:0050808 125 0.015
regulation of cell cycle GO:0051726 281 0.015
renal system development GO:0072001 225 0.015
placenta development GO:0001890 140 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
neural tube formation GO:0001841 108 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
regulation of cell cycle process GO:0010564 160 0.014
regulation of protein transport GO:0051223 163 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
cellular response to external stimulus GO:0071496 88 0.014
regulation of canonical wnt signaling pathway GO:0060828 82 0.014
regulation of cell substrate adhesion GO:0010810 73 0.014
negative regulation of neuron projection regeneration GO:0070571 3 0.014
endomembrane system organization GO:0010256 147 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
axon guidance GO:0007411 141 0.014
skeletal muscle organ development GO:0060538 163 0.014
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.014
lateral line system development GO:0048925 1 0.014
negative regulation of response to wounding GO:1903035 77 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
plasma membrane organization GO:0007009 90 0.014
glucose homeostasis GO:0042593 128 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
protein maturation GO:0051604 176 0.013
response to starvation GO:0042594 65 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
regulation of protein kinase activity GO:0045859 232 0.013
regulation of body fluid levels GO:0050878 162 0.013
cell maturation GO:0048469 127 0.013
Mouse
negative regulation of ossification GO:0030279 49 0.013
neuron projection guidance GO:0097485 141 0.013
regulation of binding GO:0051098 111 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
maintenance of location GO:0051235 89 0.013
heart morphogenesis GO:0003007 178 0.013
metal ion homeostasis GO:0055065 189 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
stem cell maintenance GO:0019827 130 0.013
regulation of hormone levels GO:0010817 211 0.013
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.013
regulation of intracellular transport GO:0032386 159 0.013
cellular homeostasis GO:0019725 240 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
stem cell proliferation GO:0072089 117 0.013
neuron projection extension GO:1990138 64 0.013
cellular protein complex assembly GO:0043623 116 0.013
t cell differentiation GO:0030217 174 0.013
b cell activation GO:0042113 161 0.013
osteoclast differentiation GO:0030316 62 0.013
negative regulation of cell motility GO:2000146 61 0.012
cerebral cortex development GO:0021987 86 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
anatomical structure homeostasis GO:0060249 145 0.012
small molecule biosynthetic process GO:0044283 132 0.012
regulation of protein catabolic process GO:0042176 108 0.012
respiratory tube development GO:0030323 167 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
negative regulation of cell migration GO:0030336 59 0.012
cell matrix adhesion GO:0007160 68 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
cell recognition GO:0008037 83 0.012
Mouse
mitotic cell cycle process GO:1903047 159 0.012
negative regulation of neuron apoptotic process GO:0043524 92 0.012
regulation of cell activation GO:0050865 289 0.012
regulation of homeostatic process GO:0032844 182 0.012
spermatogenesis GO:0007283 284 0.012
sensory system development GO:0048880 3 0.012
cellular response to acid chemical GO:0071229 68 0.012
leukocyte migration GO:0050900 124 0.012
cell activation involved in immune response GO:0002263 126 0.012
cognition GO:0050890 149 0.012
gonad development GO:0008406 141 0.012
anatomical structure maturation GO:0071695 49 0.012
regulation of proteolysis GO:0030162 164 0.012
neuron migration GO:0001764 122 0.012
epithelial cell development GO:0002064 159 0.012
response to organonitrogen compound GO:0010243 246 0.012
negative regulation of neuron death GO:1901215 98 0.011
neuromuscular process GO:0050905 99 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
glial cell differentiation GO:0010001 131 0.011
negative regulation of cell activation GO:0050866 111 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
bone development GO:0060348 120 0.011
positive regulation of neuron projection development GO:0010976 79 0.011
Mouse
development of primary sexual characteristics GO:0045137 143 0.011
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
positive regulation of response to wounding GO:1903036 66 0.011
Mouse
protein localization to membrane GO:0072657 108 0.011
homeostasis of number of cells GO:0048872 210 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
positive regulation of cell death GO:0010942 224 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
positive regulation of growth GO:0045927 104 0.011
protein targeting GO:0006605 143 0.011
cellular response to lipid GO:0071396 145 0.011
positive regulation of cell substrate adhesion GO:0010811 47 0.011
compound eye development GO:0048749 1 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
midgut development GO:0007494 4 0.011
protein secretion GO:0009306 111 0.011
establishment of tissue polarity GO:0007164 28 0.011
regulation of osteoblast differentiation GO:0045667 67 0.011
kidney development GO:0001822 213 0.011
exocytosis GO:0006887 121 0.011
neuron maturation GO:0042551 29 0.011
Mouse
cell fate commitment GO:0045165 210 0.011
regulation of protein secretion GO:0050708 82 0.011
negative regulation of cytokine production GO:0001818 84 0.011
regulation of striated muscle cell differentiation GO:0051153 81 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
appendage development GO:0048736 166 0.011
somatic stem cell maintenance GO:0035019 47 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
cardiac ventricle development GO:0003231 83 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
sensory perception of mechanical stimulus GO:0050954 107 0.010
regulation of myotube differentiation GO:0010830 62 0.010
negative regulation of organelle organization GO:0010639 90 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
response to extracellular stimulus GO:0009991 127 0.010
skin development GO:0043588 220 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010
regulation of membrane potential GO:0042391 192 0.010
regulation of myeloid cell differentiation GO:0045637 96 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
chromatin organization GO:0006325 206 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
positive regulation of interleukin 8 production GO:0032757 2 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
digestive system development GO:0055123 200 0.010
myoblast differentiation GO:0045445 52 0.010
negative regulation of protein transport GO:0051224 46 0.010
mesenchyme development GO:0060485 152 0.010
negative regulation of cell cycle GO:0045786 123 0.010
cellular protein catabolic process GO:0044257 155 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
regulation of cytokine production GO:0001817 266 0.010

Megf6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
sensory system disease DOID:0050155 0 0.013