Mus musculus

12 known processes

Tor2a

torsin family 2, member A

Tor2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.073
cellular ketone metabolic process GO:0042180 84 0.069
positive regulation of apoptotic signaling pathway GO:2001235 95 0.052
amine metabolic process GO:0009308 45 0.041
carbohydrate derivative biosynthetic process GO:1901137 183 0.040
regulation of cell activation GO:0050865 289 0.040
cation homeostasis GO:0055080 212 0.040
membrane organization GO:0061024 245 0.039
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.036
nitrogen compound transport GO:0071705 271 0.036
regulation of t cell activation GO:0050863 170 0.036
purine containing compound transmembrane transport GO:0072530 2 0.034
cellular response to cytokine stimulus GO:0071345 189 0.034
regulation of lymphocyte activation GO:0051249 240 0.034
metal ion homeostasis GO:0055065 189 0.033
transmembrane transport GO:0055085 412 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
homeostasis of number of cells GO:0048872 210 0.031
regulation of cellular ketone metabolic process GO:0010565 66 0.031
mapk cascade GO:0000165 281 0.030
immune effector process GO:0002252 321 0.030
camera type eye development GO:0043010 266 0.029
organelle localization GO:0051640 179 0.029
cellular amine metabolic process GO:0044106 44 0.029
transition metal ion homeostasis GO:0055076 54 0.029
regulation of defense response GO:0031347 233 0.028
negative regulation of immune system process GO:0002683 209 0.027
t cell activation GO:0042110 289 0.026
glycoprotein metabolic process GO:0009100 116 0.026
protein localization to nucleus GO:0034504 121 0.025
skeletal system development GO:0001501 356 0.025
leukocyte differentiation GO:0002521 342 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
regulation of apoptotic signaling pathway GO:2001233 197 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
cellular amino acid metabolic process GO:0006520 103 0.023
apoptotic signaling pathway GO:0097190 306 0.022
skin development GO:0043588 220 0.022
cation transmembrane transport GO:0098655 266 0.022
positive regulation of cell death GO:0010942 224 0.021
regulation of system process GO:0044057 200 0.021
embryonic organ morphogenesis GO:0048562 276 0.021
mitotic cell cycle GO:0000278 195 0.021
morphogenesis of a branching epithelium GO:0061138 193 0.020
response to light stimulus GO:0009416 135 0.020
hematopoietic progenitor cell differentiation GO:0002244 143 0.020
organism emergence from protective structure GO:0071684 4 0.020
cellular transition metal ion homeostasis GO:0046916 32 0.019
nuclear membrane organization GO:0071763 4 0.019
Mouse
protein oligomerization GO:0051259 67 0.019
endomembrane system organization GO:0010256 147 0.019
Mouse
cellular lipid metabolic process GO:0044255 323 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
regulation of mapk cascade GO:0043408 248 0.019
regulation of leukocyte differentiation GO:1902105 159 0.018
t cell differentiation GO:0030217 174 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
cellular chemical homeostasis GO:0055082 215 0.018
leukocyte homeostasis GO:0001776 79 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
cell killing GO:0001906 67 0.018
lymphocyte homeostasis GO:0002260 64 0.018
carbohydrate metabolic process GO:0005975 230 0.018
protein homooligomerization GO:0051260 43 0.017
nucleotide transmembrane transport GO:1901679 2 0.017
proteasomal protein catabolic process GO:0010498 98 0.017
hatching GO:0035188 4 0.017
lung development GO:0030324 164 0.017
cytokine production GO:0001816 319 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
cytokine mediated signaling pathway GO:0019221 115 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
cation transport GO:0006812 399 0.016
circulatory system process GO:0003013 197 0.016
regulation of secretion GO:0051046 274 0.015
cellular homeostasis GO:0019725 240 0.015
neuron death GO:0070997 154 0.015
peptidyl amino acid modification GO:0018193 336 0.015
regulation of secretion by cell GO:1903530 249 0.015
regulation of kinase activity GO:0043549 249 0.015
adaptive immune response GO:0002250 155 0.015
cytoplasmic transport GO:0016482 234 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
blood circulation GO:0008015 195 0.015
respiratory tube development GO:0030323 167 0.015
cellular response to lipid GO:0071396 145 0.015
sequestering of metal ion GO:0051238 19 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
leukocyte proliferation GO:0070661 172 0.014
amide transport GO:0042886 138 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
lymphocyte differentiation GO:0030098 242 0.014
t cell mediated immunity GO:0002456 50 0.014
multicellular organism growth GO:0035264 161 0.014
heart process GO:0003015 94 0.014
macromolecule catabolic process GO:0009057 281 0.014
embryonic skeletal system development GO:0048706 120 0.014
regulation of ion transport GO:0043269 215 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
lateral inhibition GO:0046331 1 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
lymphocyte mediated immunity GO:0002449 139 0.014
mitotic cell cycle process GO:1903047 159 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
gland development GO:0048732 330 0.014
nuclear division GO:0000280 158 0.014
retina development in camera type eye GO:0060041 119 0.013
regulation of intracellular transport GO:0032386 159 0.013
organelle fission GO:0048285 170 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
interleukin 6 production GO:0032635 58 0.013
endocytosis GO:0006897 168 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
cellular ion homeostasis GO:0006873 165 0.013
male gamete generation GO:0048232 285 0.013
regulation of protein kinase activity GO:0045859 232 0.013
chromatin modification GO:0016568 187 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
regulation of membrane potential GO:0042391 192 0.013
cell type specific apoptotic process GO:0097285 268 0.013
morphogenesis of a branching structure GO:0001763 203 0.013
t cell proliferation GO:0042098 120 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
blood vessel morphogenesis GO:0048514 285 0.012
wound healing GO:0042060 157 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
negative regulation of molecular function GO:0044092 258 0.012
response to acid chemical GO:0001101 111 0.012
lymphocyte proliferation GO:0046651 164 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
skeletal system morphogenesis GO:0048705 203 0.012
forebrain development GO:0030900 302 0.012
protein localization to organelle GO:0033365 185 0.012
positive regulation of protein modification process GO:0031401 299 0.012
striated muscle tissue development GO:0014706 293 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
peptide transport GO:0015833 133 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
meiotic nuclear division GO:0007126 115 0.012
epidermis development GO:0008544 187 0.012
positive regulation of transferase activity GO:0051347 167 0.012
nucleus organization GO:0006997 45 0.012
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
regulation of neuron death GO:1901214 134 0.011
appendage development GO:0048736 166 0.011
regulation of protein localization GO:0032880 231 0.011
regulation of cellular response to stress GO:0080135 159 0.011
sterol homeostasis GO:0055092 45 0.011
sensory perception GO:0007600 245 0.011
limb development GO:0060173 166 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
positive regulation of cell activation GO:0050867 158 0.011
regulation of homeostatic process GO:0032844 182 0.011
positive regulation of kinase activity GO:0033674 155 0.011
vesicle organization GO:0016050 60 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
negative regulation of protein metabolic process GO:0051248 282 0.011
sensory organ morphogenesis GO:0090596 242 0.011
intracellular protein transport GO:0006886 204 0.011
regulation of cytokine production GO:0001817 266 0.011
lipid biosynthetic process GO:0008610 179 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
response to radiation GO:0009314 165 0.011
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.011
inner ear receptor cell differentiation GO:0060113 61 0.011
positive regulation of cytokine production GO:0001819 174 0.011
response to growth factor GO:0070848 198 0.011
sequestering of calcium ion GO:0051208 18 0.011
leukocyte mediated cytotoxicity GO:0001909 62 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
regulation of heart contraction GO:0008016 77 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
negative regulation of lymphocyte activation GO:0051250 91 0.011
calcium ion homeostasis GO:0055074 127 0.011
regulation of ossification GO:0030278 112 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
peptidyl tyrosine phosphorylation GO:0018108 143 0.010
nucleobase containing small molecule metabolic process GO:0055086 352 0.010
response to temperature stimulus GO:0009266 55 0.010
rhythmic process GO:0048511 174 0.010
translation GO:0006412 93 0.010
regulation of blood pressure GO:0008217 93 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
myeloid cell differentiation GO:0030099 233 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
leukocyte mediated immunity GO:0002443 174 0.010
i kappab kinase nf kappab signaling GO:0007249 85 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
regulation of multi organism process GO:0043900 111 0.010
response to lipopolysaccharide GO:0032496 128 0.010
divalent inorganic cation transport GO:0072511 178 0.010
regulation of anatomical structure size GO:0090066 178 0.010

Tor2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
central nervous system disease DOID:331 0 0.015
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
disease of mental health DOID:150 0 0.012