Mus musculus

167 known processes

Ercc6

excision repair cross-complementing rodent repair deficiency, complementation group 6

(Aliases: C130058G22Rik,4732403I04,CSB)

Ercc6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.101
cellular amine metabolic process GO:0044106 44 0.096
apoptotic signaling pathway GO:0097190 306 0.080
amine metabolic process GO:0009308 45 0.073
dna metabolic process GO:0006259 303 0.064
leukocyte differentiation GO:0002521 342 0.061
oxidation reduction process GO:0055114 342 0.058
ras protein signal transduction GO:0007265 77 0.054
cellular lipid metabolic process GO:0044255 323 0.052
regulation of kinase activity GO:0043549 249 0.052
protein modification by small protein conjugation or removal GO:0070647 207 0.049
cellular ketone metabolic process GO:0042180 84 0.048
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
organic cyclic compound catabolic process GO:1901361 295 0.045
multicellular organism growth GO:0035264 161 0.044
macromolecule catabolic process GO:0009057 281 0.044
cellular response to dna damage stimulus GO:0006974 207 0.043
small gtpase mediated signal transduction GO:0007264 97 0.042
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.042
negative regulation of phosphorus metabolic process GO:0010563 184 0.041
regulation of cell cycle GO:0051726 281 0.041
cytokine production GO:0001816 319 0.041
cell type specific apoptotic process GO:0097285 268 0.041
cation transport GO:0006812 399 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.040
protein ubiquitination GO:0016567 171 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
protein modification by small protein conjugation GO:0032446 187 0.039
regulation of hormone levels GO:0010817 211 0.039
striated muscle tissue development GO:0014706 293 0.039
cellular nitrogen compound catabolic process GO:0044270 280 0.038
heterocycle catabolic process GO:0046700 280 0.038
sensory perception GO:0007600 245 0.038
skeletal system development GO:0001501 356 0.038
regulation of hydrolase activity GO:0051336 246 0.037
regulation of cellular catabolic process GO:0031329 242 0.037
organic hydroxy compound metabolic process GO:1901615 203 0.037
cellular response to organonitrogen compound GO:0071417 145 0.037
regulation of protein kinase activity GO:0045859 232 0.037
nitrogen compound transport GO:0071705 271 0.036
immune effector process GO:0002252 321 0.036
purine containing compound metabolic process GO:0072521 311 0.036
organonitrogen compound biosynthetic process GO:1901566 192 0.035
mapk cascade GO:0000165 281 0.035
peptidyl amino acid modification GO:0018193 336 0.035
cytoplasmic transport GO:0016482 234 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
cellular homeostasis GO:0019725 240 0.034
negative regulation of molecular function GO:0044092 258 0.034
myeloid cell differentiation GO:0030099 233 0.034
muscle system process GO:0003012 141 0.033
aromatic compound catabolic process GO:0019439 286 0.033
negative regulation of cell proliferation GO:0008285 296 0.033
negative regulation of phosphate metabolic process GO:0045936 184 0.033
protein maturation GO:0051604 176 0.033
positive regulation of protein phosphorylation GO:0001934 242 0.033
regulation of cell motility GO:2000145 236 0.033
regulation of system process GO:0044057 200 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
regulation of transferase activity GO:0051338 263 0.032
regulation of protein localization GO:0032880 231 0.032
dna repair GO:0006281 107 0.032
mrna metabolic process GO:0016071 84 0.032
maintenance of location GO:0051235 89 0.032
male gamete generation GO:0048232 285 0.031
transmembrane transport GO:0055085 412 0.031
reactive oxygen species metabolic process GO:0072593 84 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.030
cellular macromolecule catabolic process GO:0044265 206 0.030
heart morphogenesis GO:0003007 178 0.030
positive regulation of protein modification process GO:0031401 299 0.030
circulatory system process GO:0003013 197 0.030
spermatogenesis GO:0007283 284 0.030
camera type eye development GO:0043010 266 0.029
response to oxidative stress GO:0006979 123 0.029
t cell activation GO:0042110 289 0.029
fat cell differentiation GO:0045444 160 0.029
cellular response to hormone stimulus GO:0032870 150 0.029
response to organonitrogen compound GO:0010243 246 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
endocytosis GO:0006897 168 0.029
small molecule biosynthetic process GO:0044283 132 0.029
regulation of cell migration GO:0030334 219 0.028
blood circulation GO:0008015 195 0.028
regulation of organelle organization GO:0033043 289 0.028
response to radiation GO:0009314 165 0.028
cellular response to lipid GO:0071396 145 0.028
regulation of neuron differentiation GO:0045664 281 0.028
nuclear transport GO:0051169 139 0.028
regulation of apoptotic signaling pathway GO:2001233 197 0.027
cation transmembrane transport GO:0098655 266 0.027
placenta development GO:0001890 140 0.027
positive regulation of mapk cascade GO:0043410 170 0.026
regulation of secretion by cell GO:1903530 249 0.026
nucleocytoplasmic transport GO:0006913 139 0.026
rho protein signal transduction GO:0007266 32 0.026
cellular chemical homeostasis GO:0055082 215 0.026
metal ion homeostasis GO:0055065 189 0.025
negative regulation of immune system process GO:0002683 209 0.025
regulation of cell activation GO:0050865 289 0.025
epithelial cell development GO:0002064 159 0.024
lymphocyte proliferation GO:0046651 164 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.024
regulation of lymphocyte activation GO:0051249 240 0.024
epithelial cell proliferation GO:0050673 174 0.024
regulation of ras protein signal transduction GO:0046578 114 0.024
activation of immune response GO:0002253 138 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
embryonic organ morphogenesis GO:0048562 276 0.024
muscle cell differentiation GO:0042692 261 0.024
protein catabolic process GO:0030163 221 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
modification dependent protein catabolic process GO:0019941 133 0.023
b cell activation GO:0042113 161 0.023
germ cell development GO:0007281 185 0.023
regulation of ion transport GO:0043269 215 0.023
mitochondrion organization GO:0007005 134 0.023
methylation GO:0032259 134 0.023
forebrain development GO:0030900 302 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
regulation of anatomical structure size GO:0090066 178 0.023
ribose phosphate metabolic process GO:0019693 291 0.023
myeloid leukocyte differentiation GO:0002573 119 0.023
protein processing GO:0016485 163 0.023
gland development GO:0048732 330 0.022
anion transport GO:0006820 177 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
inorganic ion transmembrane transport GO:0098660 234 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
negative regulation of phosphorylation GO:0042326 166 0.022
neuron death GO:0070997 154 0.022
regulation of mapk cascade GO:0043408 248 0.022
organic hydroxy compound biosynthetic process GO:1901617 77 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
respiratory system development GO:0060541 190 0.022
response to organic cyclic compound GO:0014070 198 0.022
cation homeostasis GO:0055080 212 0.021
leukocyte activation involved in immune response GO:0002366 126 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
nucleotide metabolic process GO:0009117 332 0.021
locomotory behavior GO:0007626 195 0.021
regulation of cellular response to stress GO:0080135 159 0.021
blood vessel morphogenesis GO:0048514 285 0.021
ion transmembrane transport GO:0034220 361 0.021
divalent metal ion transport GO:0070838 172 0.021
regulation of secretion GO:0051046 274 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
rna processing GO:0006396 105 0.021
nucleoside catabolic process GO:0009164 206 0.021
ubiquitin dependent protein catabolic process GO:0006511 129 0.021
regulation of cytokine production GO:0001817 266 0.021
ossification GO:0001503 216 0.021
organelle fission GO:0048285 170 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
gonad development GO:0008406 141 0.021
lipid localization GO:0010876 126 0.021
monocarboxylic acid metabolic process GO:0032787 191 0.021
regulation of membrane potential GO:0042391 192 0.021
regulation of defense response GO:0031347 233 0.020
leukocyte mediated immunity GO:0002443 174 0.020
purine nucleoside metabolic process GO:0042278 241 0.020
response to acid chemical GO:0001101 111 0.020
leukocyte proliferation GO:0070661 172 0.020
response to peptide GO:1901652 136 0.020
homeostasis of number of cells GO:0048872 210 0.020
muscle tissue development GO:0060537 308 0.020
actin cytoskeleton organization GO:0030036 220 0.020
sensory organ morphogenesis GO:0090596 242 0.020
regulation of proteolysis GO:0030162 164 0.020
cellular ion homeostasis GO:0006873 165 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.019
regulation of adaptive immune response GO:0002819 90 0.019
rna splicing GO:0008380 54 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
membrane organization GO:0061024 245 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
cellular calcium ion homeostasis GO:0006874 119 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
cognition GO:0050890 149 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.019
regulation of leukocyte differentiation GO:1902105 159 0.019
stem cell differentiation GO:0048863 268 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
divalent inorganic cation transport GO:0072511 178 0.019
regulation of epithelial cell proliferation GO:0050678 141 0.019
renal system development GO:0072001 225 0.018
intrinsic apoptotic signaling pathway GO:0097193 132 0.018
calcium ion transport GO:0006816 159 0.018
synaptic transmission GO:0007268 329 0.018
histone modification GO:0016570 159 0.018
positive regulation of cellular catabolic process GO:0031331 148 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
immune response regulating signaling pathway GO:0002764 125 0.018
cell adhesion GO:0007155 329 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
positive regulation of transferase activity GO:0051347 167 0.018
nucleoside metabolic process GO:0009116 246 0.018
meiotic cell cycle GO:0051321 122 0.018
g protein coupled receptor signaling pathway GO:0007186 243 0.018
hormone metabolic process GO:0042445 86 0.018
synapse organization GO:0050808 125 0.018
alcohol metabolic process GO:0006066 116 0.018
positive regulation of cell death GO:0010942 224 0.018
chromatin organization GO:0006325 206 0.018
lipid biosynthetic process GO:0008610 179 0.018
regulation of body fluid levels GO:0050878 162 0.018
rhythmic process GO:0048511 174 0.018
cell activation involved in immune response GO:0002263 126 0.017
endomembrane system organization GO:0010256 147 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
digestive tract development GO:0048565 190 0.017
regulation of protein transport GO:0051223 163 0.017
response to extracellular stimulus GO:0009991 127 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
lymphocyte activation involved in immune response GO:0002285 93 0.017
positive regulation of kinase activity GO:0033674 155 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
lateral inhibition GO:0046331 1 0.017
embryonic limb morphogenesis GO:0030326 126 0.017
organophosphate catabolic process GO:0046434 232 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
digestive system development GO:0055123 200 0.017
adaptive immune response GO:0002250 155 0.017
regulation of response to wounding GO:1903034 189 0.017
regulation of homeostatic process GO:0032844 182 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
skeletal system morphogenesis GO:0048705 203 0.017
central nervous system neuron differentiation GO:0021953 162 0.017
chromatin modification GO:0016568 187 0.017
embryonic appendage morphogenesis GO:0035113 126 0.017
axonogenesis GO:0007409 274 0.017
wnt signaling pathway GO:0016055 188 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
response to lipopolysaccharide GO:0032496 128 0.016
regulation of protein processing GO:0070613 96 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
regulation of neuron death GO:1901214 134 0.016
telencephalon development GO:0021537 186 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
positive regulation of cell development GO:0010720 237 0.016
respiratory tube development GO:0030323 167 0.016
organelle assembly GO:0070925 177 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
organic acid biosynthetic process GO:0016053 86 0.016
organic anion transport GO:0015711 137 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
angiogenesis GO:0001525 201 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
appendage development GO:0048736 166 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
positive regulation of immune effector process GO:0002699 107 0.016
ear development GO:0043583 200 0.016
intracellular protein transport GO:0006886 204 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
regulation of protein maturation GO:1903317 96 0.016
innate immune response GO:0045087 157 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
protein secretion GO:0009306 111 0.016
t cell proliferation GO:0042098 120 0.016
glucose homeostasis GO:0042593 128 0.016
protein localization to organelle GO:0033365 185 0.016
regulation of t cell activation GO:0050863 170 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
embryonic placenta development GO:0001892 98 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
positive regulation of nervous system development GO:0051962 221 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
dna recombination GO:0006310 92 0.015
response to insulin GO:0032868 100 0.015
negative regulation of growth GO:0045926 99 0.015
stem cell development GO:0048864 219 0.015
glycerolipid metabolic process GO:0046486 122 0.015
negative regulation of cell cycle GO:0045786 123 0.015
regulation of cell projection organization GO:0031344 206 0.015
rna splicing via transesterification reactions GO:0000375 43 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
protein targeting GO:0006605 143 0.015
purine containing compound catabolic process GO:0072523 213 0.015
ameboidal type cell migration GO:0001667 128 0.015
regulation of transmembrane transport GO:0034762 128 0.015
action potential GO:0001508 78 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
learning or memory GO:0007611 148 0.015
single organism nuclear import GO:1902593 95 0.015
steroid metabolic process GO:0008202 119 0.015
production of molecular mediator of immune response GO:0002440 103 0.015
skeletal muscle organ development GO:0060538 163 0.015
nuclear division GO:0000280 158 0.015
appendage morphogenesis GO:0035107 149 0.015
limb development GO:0060173 166 0.015
urogenital system development GO:0001655 261 0.015
sequestering of calcium ion GO:0051208 18 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
fatty acid metabolic process GO:0006631 121 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
nucleotide catabolic process GO:0009166 217 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
regulation of protein catabolic process GO:0042176 108 0.014
ear morphogenesis GO:0042471 118 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
regulation of intracellular transport GO:0032386 159 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
female gamete generation GO:0007292 74 0.014
regulation of ossification GO:0030278 112 0.014
positive regulation of cytokine production GO:0001819 174 0.014
chemotaxis GO:0006935 247 0.014
regulation of cell cycle process GO:0010564 160 0.014
sulfur compound metabolic process GO:0006790 100 0.014
neuron apoptotic process GO:0051402 142 0.014
circadian regulation of gene expression GO:0032922 48 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
muscle contraction GO:0006936 101 0.014
inflammatory response GO:0006954 244 0.014
response to growth factor GO:0070848 198 0.014
carbohydrate metabolic process GO:0005975 230 0.014
immune response activating signal transduction GO:0002757 116 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
heart process GO:0003015 94 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
mrna processing GO:0006397 63 0.014
neural tube development GO:0021915 160 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
positive regulation of lymphocyte activation GO:0051251 140 0.014
tube formation GO:0035148 140 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
multi multicellular organism process GO:0044706 109 0.014
myotube differentiation GO:0014902 105 0.014
macromolecule methylation GO:0043414 120 0.013
anatomical structure homeostasis GO:0060249 145 0.013
cellular alcohol biosynthetic process GO:0044108 3 0.013
peptide transport GO:0015833 133 0.013
tissue remodeling GO:0048771 102 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
regulation of protein secretion GO:0050708 82 0.013
extracellular structure organization GO:0043062 148 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
alpha beta t cell activation GO:0046631 91 0.013
stem cell proliferation GO:0072089 117 0.013
response to nutrient levels GO:0031667 109 0.013
negative regulation of protein modification process GO:0031400 163 0.013
epithelial cell morphogenesis GO:0003382 41 0.013
response to uv GO:0009411 44 0.013
oogenesis GO:0048477 56 0.013
regulation of t cell proliferation GO:0042129 92 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
regulation of organ morphogenesis GO:2000027 144 0.013
t cell differentiation GO:0030217 174 0.013
epithelial tube formation GO:0072175 130 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
hormone secretion GO:0046879 128 0.013
negative regulation of hormone metabolic process GO:0032351 4 0.013
cellular protein complex assembly GO:0043623 116 0.013
regulation of inflammatory response GO:0050727 147 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
mitotic cell cycle process GO:1903047 159 0.013
cellular response to oxidative stress GO:0034599 76 0.013
calcium ion homeostasis GO:0055074 127 0.013
response to peptide hormone GO:0043434 127 0.013
development of primary sexual characteristics GO:0045137 143 0.013
regulation of cellular component size GO:0032535 121 0.013
vacuole organization GO:0007033 38 0.013
regulation of metal ion transport GO:0010959 106 0.013
cellular protein catabolic process GO:0044257 155 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
regulation of cell division GO:0051302 76 0.013
negative regulation of hydrolase activity GO:0051346 71 0.012
response to inorganic substance GO:0010035 96 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.012
regulation of striated muscle cell differentiation GO:0051153 81 0.012
response to reactive oxygen species GO:0000302 56 0.012
regionalization GO:0003002 337 0.012
regulation of fat cell differentiation GO:0045598 81 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
regulation of blood pressure GO:0008217 93 0.012
kidney development GO:0001822 213 0.012
positive regulation of growth GO:0045927 104 0.012
negative regulation of defense response GO:0031348 77 0.012
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.012
hindbrain development GO:0030902 128 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
erk1 and erk2 cascade GO:0070371 77 0.012
sensory perception of sound GO:0007605 97 0.012
regulation of cell adhesion GO:0030155 154 0.012
mitotic cell cycle GO:0000278 195 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
meiotic nuclear division GO:0007126 115 0.012
digestive tract morphogenesis GO:0048546 147 0.012
positive regulation of cell activation GO:0050867 158 0.012
protein import GO:0017038 101 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
heart contraction GO:0060047 93 0.012
biomineral tissue development GO:0031214 64 0.012
regulation of mrna processing GO:0050684 41 0.012
regulation of production of molecular mediator of immune response GO:0002700 65 0.012
protein localization to nucleus GO:0034504 121 0.012
leukocyte migration GO:0050900 124 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
nuclear export GO:0051168 34 0.012
negative regulation of protein maturation GO:1903318 79 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.012
cellular response to external stimulus GO:0071496 88 0.012
compound eye development GO:0048749 1 0.012
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.012
protein kinase b signaling GO:0043491 74 0.012
phospholipid metabolic process GO:0006644 87 0.012
telomere maintenance in response to dna damage GO:0043247 4 0.012
energy derivation by oxidation of organic compounds GO:0015980 77 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
rna interference GO:0016246 2 0.011
negative regulation of protein processing GO:0010955 79 0.011
cell maturation GO:0048469 127 0.011
carbohydrate homeostasis GO:0033500 128 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
protein localization to membrane GO:0072657 108 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
cellular response to peptide GO:1901653 92 0.011
organelle localization GO:0051640 179 0.011
sequestering of metal ion GO:0051238 19 0.011
glycoprotein metabolic process GO:0009100 116 0.011
actin filament organization GO:0007015 113 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
organic acid transport GO:0015849 101 0.011
cardiac muscle tissue development GO:0048738 130 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
amide transport GO:0042886 138 0.011
limb morphogenesis GO:0035108 149 0.011
cardiac chamber morphogenesis GO:0003206 93 0.011
regulation of myotube differentiation GO:0010830 62 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
regulation of cellular protein catabolic process GO:1903362 61 0.011
cdp choline pathway GO:0006657 2 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
cofactor metabolic process GO:0051186 80 0.011
negative regulation of neuron death GO:1901215 98 0.011
negative regulation of transferase activity GO:0051348 85 0.011
fertilization GO:0009566 127 0.011
negative regulation of mapk cascade GO:0043409 65 0.011
tissue homeostasis GO:0001894 115 0.011
organic hydroxy compound transport GO:0015850 93 0.011
regulation of vacuole organization GO:0044088 4 0.011
bone development GO:0060348 120 0.011
developmental maturation GO:0021700 193 0.011
single organism cell adhesion GO:0098602 156 0.011
receptor mediated endocytosis GO:0006898 51 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
positive regulation of proteolysis GO:0045862 85 0.011
negative regulation of t cell activation GO:0050868 65 0.011
mrna splicing via spliceosome GO:0000398 43 0.011
regulation of mrna splicing via spliceosome GO:0048024 32 0.011
regulation of cardiac chamber formation GO:1901210 1 0.011
negative regulation of nervous system development GO:0051961 156 0.011
memory GO:0007613 58 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
negative regulation of cell activation GO:0050866 111 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
negative regulation of endothelial cell migration GO:0010596 4 0.011
muscle cell development GO:0055001 133 0.011

Ercc6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.025
disease of anatomical entity DOID:7 0 0.025
disease of metabolism DOID:0014667 0 0.022
nervous system disease DOID:863 0 0.022
musculoskeletal system disease DOID:17 0 0.021
connective tissue disease DOID:65 0 0.019
hematopoietic system disease DOID:74 0 0.019
bone disease DOID:0080001 0 0.018
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
inherited metabolic disorder DOID:655 0 0.016
blood coagulation disease DOID:1247 0 0.011