Mus musculus

12 known processes

Uba3

ubiquitin-like modifier activating enzyme 3

(Aliases: A830034N06Rik,Ube1c,AW546539,AI848246,AI256736)

Uba3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic cyclic compound catabolic process GO:1901361 295 0.787
cellular protein catabolic process GO:0044257 155 0.645
guanosine containing compound metabolic process GO:1901068 144 0.621
ribonucleoside triphosphate metabolic process GO:0009199 220 0.501
guanosine containing compound catabolic process GO:1901069 144 0.446
carbohydrate derivative catabolic process GO:1901136 231 0.416
glycosyl compound metabolic process GO:1901657 246 0.378
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.376
organelle localization GO:0051640 179 0.347
macromolecule catabolic process GO:0009057 281 0.334
nucleoside triphosphate metabolic process GO:0009141 230 0.328
purine containing compound catabolic process GO:0072523 213 0.327
establishment of organelle localization GO:0051656 122 0.326
purine ribonucleotide catabolic process GO:0009154 208 0.312
nucleotide catabolic process GO:0009166 217 0.311
nucleotide metabolic process GO:0009117 332 0.297
purine ribonucleoside catabolic process GO:0046130 205 0.294
regulation of cellular catabolic process GO:0031329 242 0.288
cellular macromolecule catabolic process GO:0044265 206 0.284
nucleoside phosphate metabolic process GO:0006753 338 0.284
protein neddylation GO:0045116 1 0.273
Yeast Worm
ribonucleoside triphosphate catabolic process GO:0009203 199 0.270
protein modification by small protein conjugation or removal GO:0070647 207 0.269
Yeast Worm
cellularization GO:0007349 1 0.262
purine ribonucleoside metabolic process GO:0046128 241 0.252
synaptic transmission GO:0007268 329 0.249
purine nucleoside metabolic process GO:0042278 241 0.246
glycosyl compound catabolic process GO:1901658 206 0.221
organophosphate catabolic process GO:0046434 232 0.219
proteasomal protein catabolic process GO:0010498 98 0.217
gtp metabolic process GO:0046039 144 0.216
nucleoside phosphate catabolic process GO:1901292 222 0.213
gtp catabolic process GO:0006184 143 0.195
ribose phosphate metabolic process GO:0019693 291 0.193
aromatic compound catabolic process GO:0019439 286 0.192
purine containing compound metabolic process GO:0072521 311 0.191
modification dependent protein catabolic process GO:0019941 133 0.190
heterocycle catabolic process GO:0046700 280 0.189
protein catabolic process GO:0030163 221 0.184
purine ribonucleotide metabolic process GO:0009150 290 0.181
nucleoside catabolic process GO:0009164 206 0.178
negative regulation of protein metabolic process GO:0051248 282 0.167
ribonucleoside catabolic process GO:0042454 206 0.165
dna metabolic process GO:0006259 303 0.163
cellular nitrogen compound catabolic process GO:0044270 280 0.153
ribonucleotide metabolic process GO:0009259 291 0.151
nucleobase containing small molecule metabolic process GO:0055086 352 0.148
positive regulation of dna templated transcription elongation GO:0032786 2 0.141
nucleoside triphosphate catabolic process GO:0009143 205 0.141
ribonucleoside metabolic process GO:0009119 245 0.140
purine nucleoside catabolic process GO:0006152 205 0.128
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.128
purine nucleoside triphosphate metabolic process GO:0009144 226 0.126
modification dependent macromolecule catabolic process GO:0043632 133 0.120
organonitrogen compound catabolic process GO:1901565 264 0.114
germ cell development GO:0007281 185 0.111
regulation of cell cycle GO:0051726 281 0.111
purine nucleoside triphosphate catabolic process GO:0009146 203 0.111
nucleoside metabolic process GO:0009116 246 0.102
regulation of cell projection organization GO:0031344 206 0.100
cell division GO:0051301 120 0.095
purine nucleotide metabolic process GO:0006163 302 0.095
cellular response to dna damage stimulus GO:0006974 207 0.093
ribonucleotide catabolic process GO:0009261 208 0.093
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.089
regulation of mitochondrial fission GO:0090140 3 0.085
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.081
negative regulation of synapse assembly GO:0051964 3 0.077
intra golgi vesicle mediated transport GO:0006891 1 0.076
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.076
regulation of cell cycle process GO:0010564 160 0.075
regulation of protein catabolic process GO:0042176 108 0.074
male gamete generation GO:0048232 285 0.074
spermatid differentiation GO:0048515 115 0.074
positive regulation of cellular catabolic process GO:0031331 148 0.072
cytokinesis GO:0000910 17 0.071
purine nucleotide catabolic process GO:0006195 211 0.063
negative regulation of cellular protein metabolic process GO:0032269 247 0.062
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.062
regulation of organelle organization GO:0033043 289 0.060
spermatid development GO:0007286 108 0.058
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.056
ubiquitin dependent protein catabolic process GO:0006511 129 0.053
axonogenesis GO:0007409 274 0.053
regulation of protein localization GO:0032880 231 0.051
meiotic cell cycle process GO:1903046 77 0.047
regulation of cellular component size GO:0032535 121 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.045
regulation of neuron projection development GO:0010975 169 0.045
protein localization to organelle GO:0033365 185 0.044
protein modification by small protein conjugation GO:0032446 187 0.044
Yeast Worm
metaphase plate congression GO:0051310 2 0.043
cell growth GO:0016049 130 0.042
regulation of mitotic cell cycle GO:0007346 126 0.042
positive regulation of cell death GO:0010942 224 0.041
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.040
regulation of long term synaptic potentiation GO:1900271 4 0.039
regulation of cell migration GO:0030334 219 0.037
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.037
small gtpase mediated signal transduction GO:0007264 97 0.036
cytoplasmic transport GO:0016482 234 0.035
striated muscle tissue development GO:0014706 293 0.035
proteasome assembly GO:0043248 1 0.035
regulation of cell motility GO:2000145 236 0.035
dna templated transcription elongation GO:0006354 13 0.034
stem cell differentiation GO:0048863 268 0.034
meiotic cell cycle GO:0051321 122 0.033
regulation of anatomical structure size GO:0090066 178 0.032
neuron projection guidance GO:0097485 141 0.031
regulation of vesicle mediated transport GO:0060627 139 0.031
regulation of cell size GO:0008361 72 0.030
membrane fusion GO:0061025 38 0.030
synapse organization GO:0050808 125 0.029
regulation of secretion GO:0051046 274 0.028
regulation of kinase activity GO:0043549 249 0.027
regulation of nucleotide catabolic process GO:0030811 122 0.027
mitotic cell cycle GO:0000278 195 0.026
nitrogen compound transport GO:0071705 271 0.026
exocytosis GO:0006887 121 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
regulation of neuron differentiation GO:0045664 281 0.025
regulation of protein transport GO:0051223 163 0.025
regulation of jnk cascade GO:0046328 62 0.024
regulation of mapk cascade GO:0043408 248 0.024
endomembrane system organization GO:0010256 147 0.024
regulation of proteolysis GO:0030162 164 0.024
vesicle localization GO:0051648 86 0.023
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.023
ras protein signal transduction GO:0007265 77 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
negative regulation of mitotic cell cycle GO:0045930 58 0.023
regulation of stress activated mapk cascade GO:0032872 69 0.023
chromatin modification GO:0016568 187 0.023
ribonucleoside monophosphate metabolic process GO:0009161 80 0.022
hematopoietic progenitor cell differentiation GO:0002244 143 0.022
mitotic cytokinesis GO:0000281 4 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
chromatin organization GO:0006325 206 0.021
spermatogenesis GO:0007283 284 0.020
regulation of secretion by cell GO:1903530 249 0.020
positive regulation of secretion GO:0051047 130 0.020
lipid localization GO:0010876 126 0.020
positive regulation of cell cycle GO:0045787 92 0.020
membrane organization GO:0061024 245 0.020
microtubule based process GO:0007017 236 0.020
mitotic cell cycle process GO:1903047 159 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
negative regulation of cell cycle process GO:0010948 69 0.019
developmental cell growth GO:0048588 84 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
positive regulation of proteolysis GO:0045862 85 0.018
positive regulation of oxidative stress induced cell death GO:1903209 6 0.018
positive regulation of secretion by cell GO:1903532 114 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
golgi vesicle transport GO:0048193 30 0.018
chromosome segregation GO:0007059 48 0.018
regionalization GO:0003002 337 0.018
establishment of vesicle localization GO:0051650 81 0.017
macromolecular complex disassembly GO:0032984 43 0.017
regulation of cellular response to stress GO:0080135 159 0.017
response to light stimulus GO:0009416 135 0.017
cellular protein complex assembly GO:0043623 116 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
transmembrane transport GO:0055085 412 0.017
body morphogenesis GO:0010171 45 0.017
negative regulation of immune system process GO:0002683 209 0.016
purine nucleoside monophosphate metabolic process GO:0009126 81 0.016
mitochondrion organization GO:0007005 134 0.016
epithelial cell proliferation GO:0050673 174 0.016
response to organonitrogen compound GO:0010243 246 0.016
neuron neuron synaptic transmission GO:0007270 69 0.015
regulation of cellular protein catabolic process GO:1903362 61 0.015
regulation of cell shape GO:0008360 39 0.015
intracellular protein transport GO:0006886 204 0.015
endoplasmic reticulum organization GO:0007029 10 0.015
isg15 protein conjugation GO:0032020 4 0.015
mitochondrion distribution GO:0048311 4 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
negative regulation of protein modification process GO:0031400 163 0.015
cell adhesion GO:0007155 329 0.015
telencephalon development GO:0021537 186 0.015
protein ubiquitination GO:0016567 171 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
regulation of ras gtpase activity GO:0032318 88 0.015
organelle fission GO:0048285 170 0.015
histone modification GO:0016570 159 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
positive regulation of mitochondrial fission GO:0090141 2 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
dna repair GO:0006281 107 0.014
protein targeting GO:0006605 143 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.013
regulation of cell growth GO:0001558 91 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
maintenance of location GO:0051235 89 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.013
negative regulation of protein processing GO:0010955 79 0.013
nucleus localization GO:0051647 20 0.013
positive regulation of cell development GO:0010720 237 0.013
positive regulation of nervous system development GO:0051962 221 0.013
regulation of protein kinase activity GO:0045859 232 0.012
cell maturation GO:0048469 127 0.012
negative regulation of nervous system development GO:0051961 156 0.012
rho protein signal transduction GO:0007266 32 0.012
learning or memory GO:0007611 148 0.012
regulation of hydrolase activity GO:0051336 246 0.012
wnt signaling pathway GO:0016055 188 0.012
vesicle organization GO:0016050 60 0.012
cell cycle g1 s phase transition GO:0044843 57 0.012
protein modification by small protein removal GO:0070646 21 0.012
forebrain development GO:0030900 302 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
cellular amine metabolic process GO:0044106 44 0.012
skeletal muscle cell differentiation GO:0035914 66 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 9 0.011
carbohydrate homeostasis GO:0033500 128 0.011
response to growth factor GO:0070848 198 0.011
stress activated mapk cascade GO:0051403 80 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.011
negative regulation of cell motility GO:2000146 61 0.011
neuron migration GO:0001764 122 0.011
regulation of proteasomal protein catabolic process GO:0061136 46 0.011
myeloid cell differentiation GO:0030099 233 0.011
response to transforming growth factor beta GO:0071559 88 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
microtubule cytoskeleton organization GO:0000226 157 0.010
neurotransmitter transport GO:0006836 76 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
regulation of translation GO:0006417 71 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
gonad development GO:0008406 141 0.010

Uba3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
central nervous system disease DOID:331 0 0.016
neurodegenerative disease DOID:1289 0 0.016