Mus musculus

0 known processes

Defb25

defensin beta 25

(Aliases: BD-25,mBD-25,OTTMUSG00000015862)

Defb25 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transmission of nerve impulse GO:0019226 76 0.055
amine metabolic process GO:0009308 45 0.047
action potential GO:0001508 78 0.046
cellular amino acid metabolic process GO:0006520 103 0.043
transmembrane transport GO:0055085 412 0.043
cellular amine metabolic process GO:0044106 44 0.042
regulation of membrane potential GO:0042391 192 0.041
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
skeletal system development GO:0001501 356 0.039
cation transport GO:0006812 399 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.036
multicellular organismal signaling GO:0035637 91 0.036
cellular ketone metabolic process GO:0042180 84 0.036
nitrogen compound transport GO:0071705 271 0.035
male gamete generation GO:0048232 285 0.035
neuronal action potential GO:0019228 54 0.033
spermatogenesis GO:0007283 284 0.033
ion transmembrane transport GO:0034220 361 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
inflammatory response GO:0006954 244 0.029
cellular response to lipid GO:0071396 145 0.028
cytokine production GO:0001816 319 0.028
regulation of cell activation GO:0050865 289 0.028
regulation of secretion by cell GO:1903530 249 0.028
negative regulation of cell proliferation GO:0008285 296 0.028
camera type eye development GO:0043010 266 0.028
circulatory system process GO:0003013 197 0.027
axonogenesis GO:0007409 274 0.027
forebrain development GO:0030900 302 0.027
cation transmembrane transport GO:0098655 266 0.027
inorganic ion transmembrane transport GO:0098660 234 0.026
hematopoietic progenitor cell differentiation GO:0002244 143 0.026
nucleoside phosphate metabolic process GO:0006753 338 0.026
response to organonitrogen compound GO:0010243 246 0.026
positive regulation of nervous system development GO:0051962 221 0.026
developmental maturation GO:0021700 193 0.025
leukocyte differentiation GO:0002521 342 0.025
g protein coupled receptor signaling pathway GO:0007186 243 0.024
cation homeostasis GO:0055080 212 0.024
metal ion homeostasis GO:0055065 189 0.024
regulation of defense response GO:0031347 233 0.024
sensory organ morphogenesis GO:0090596 242 0.024
oxidation reduction process GO:0055114 342 0.024
regulation of system process GO:0044057 200 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
cellular ion homeostasis GO:0006873 165 0.023
cellular chemical homeostasis GO:0055082 215 0.023
sensory perception GO:0007600 245 0.023
cellular metal ion homeostasis GO:0006875 151 0.022
cellular homeostasis GO:0019725 240 0.022
regulation of cytokine production GO:0001817 266 0.022
monocarboxylic acid metabolic process GO:0032787 191 0.022
regulation of secretion GO:0051046 274 0.021
skin development GO:0043588 220 0.021
carbohydrate metabolic process GO:0005975 230 0.021
renal system development GO:0072001 225 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
blood vessel morphogenesis GO:0048514 285 0.021
gland development GO:0048732 330 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
positive regulation of protein modification process GO:0031401 299 0.021
positive regulation of cell development GO:0010720 237 0.021
defense response to other organism GO:0098542 197 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
cell type specific apoptotic process GO:0097285 268 0.020
purine containing compound metabolic process GO:0072521 311 0.020
t cell activation GO:0042110 289 0.020
ossification GO:0001503 216 0.020
regulation of neuron differentiation GO:0045664 281 0.020
immune effector process GO:0002252 321 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
central nervous system neuron differentiation GO:0021953 162 0.019
nucleotide metabolic process GO:0009117 332 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
striated muscle tissue development GO:0014706 293 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
regulation of protein localization GO:0032880 231 0.019
regulation of cell cycle GO:0051726 281 0.018
blood circulation GO:0008015 195 0.018
stem cell differentiation GO:0048863 268 0.018
multicellular organism growth GO:0035264 161 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
germ cell development GO:0007281 185 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
dna metabolic process GO:0006259 303 0.018
cell adhesion GO:0007155 329 0.018
kidney development GO:0001822 213 0.018
lymphocyte differentiation GO:0030098 242 0.018
cytoplasmic transport GO:0016482 234 0.018
regulation of organelle organization GO:0033043 289 0.018
purine nucleotide metabolic process GO:0006163 302 0.017
regulation of response to wounding GO:1903034 189 0.017
cellular divalent inorganic cation homeostasis GO:0072503 127 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
regionalization GO:0003002 337 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.017
protein processing GO:0016485 163 0.017
regulation of ion transport GO:0043269 215 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
regulation of mapk cascade GO:0043408 248 0.016
ensheathment of neurons GO:0007272 76 0.016
muscle cell differentiation GO:0042692 261 0.016
response to organic cyclic compound GO:0014070 198 0.016
anion transport GO:0006820 177 0.016
cellular lipid metabolic process GO:0044255 323 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
kidney epithelium development GO:0072073 121 0.016
axon ensheathment GO:0008366 76 0.016
muscle tissue development GO:0060537 308 0.016
regulation of cell motility GO:2000145 236 0.016
calcium ion homeostasis GO:0055074 127 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
negative regulation of nervous system development GO:0051961 156 0.015
organic anion transport GO:0015711 137 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
response to acid chemical GO:0001101 111 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.015
tissue homeostasis GO:0001894 115 0.015
fat cell differentiation GO:0045444 160 0.015
response to lipopolysaccharide GO:0032496 128 0.015
respiratory system development GO:0060541 190 0.015
macromolecule catabolic process GO:0009057 281 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
nucleoside phosphate biosynthetic process GO:1901293 79 0.015
negative regulation of immune system process GO:0002683 209 0.015
urogenital system development GO:0001655 261 0.015
protein maturation GO:0051604 176 0.015
protein ubiquitination GO:0016567 171 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
regulation of kinase activity GO:0043549 249 0.015
ras protein signal transduction GO:0007265 77 0.015
protein secretion GO:0009306 111 0.015
regulation of transferase activity GO:0051338 263 0.014
cellular response to acid chemical GO:0071229 68 0.014
myelination GO:0042552 74 0.014
multi multicellular organism process GO:0044706 109 0.014
divalent inorganic cation transport GO:0072511 178 0.014
regulation of t cell activation GO:0050863 170 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
ear development GO:0043583 200 0.014
heart process GO:0003015 94 0.014
regulation of inflammatory response GO:0050727 147 0.014
response to extracellular stimulus GO:0009991 127 0.014
amide transport GO:0042886 138 0.014
muscle contraction GO:0006936 101 0.014
regulation of hormone levels GO:0010817 211 0.014
defense response to bacterium GO:0042742 119 0.014
synaptic transmission GO:0007268 329 0.014
regulation of anatomical structure size GO:0090066 178 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
cognition GO:0050890 149 0.014
carbohydrate homeostasis GO:0033500 128 0.014
intracellular protein transport GO:0006886 204 0.014
regulation of homeostatic process GO:0032844 182 0.014
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
mapk cascade GO:0000165 281 0.014
chemotaxis GO:0006935 247 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
innate immune response GO:0045087 157 0.014
response to growth factor GO:0070848 198 0.014
placenta development GO:0001890 140 0.013
regulation of cell projection organization GO:0031344 206 0.013
positive regulation of cell death GO:0010942 224 0.013
regulation of action potential GO:0098900 4 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
leukocyte migration GO:0050900 124 0.013
myeloid cell differentiation GO:0030099 233 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
glial cell differentiation GO:0010001 131 0.013
regulation of body fluid levels GO:0050878 162 0.013
cell recognition GO:0008037 83 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
regulation of cell migration GO:0030334 219 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
conditioned taste aversion GO:0001661 4 0.013
skeletal system morphogenesis GO:0048705 203 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
stem cell development GO:0048864 219 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
apoptotic signaling pathway GO:0097190 306 0.013
positive regulation of cell activation GO:0050867 158 0.013
peptide hormone secretion GO:0030072 109 0.013
connective tissue development GO:0061448 179 0.013
organic cyclic compound catabolic process GO:1901361 295 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
leukocyte mediated immunity GO:0002443 174 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
locomotory behavior GO:0007626 195 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.013
regulation of protein transport GO:0051223 163 0.012
heart contraction GO:0060047 93 0.012
membrane organization GO:0061024 245 0.012
glucose homeostasis GO:0042593 128 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
organic hydroxy compound transport GO:0015850 93 0.012
exocytosis GO:0006887 121 0.012
regulation of neuron projection development GO:0010975 169 0.012
protein catabolic process GO:0030163 221 0.012
protein localization to organelle GO:0033365 185 0.012
hormone secretion GO:0046879 128 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
regulation of protein kinase activity GO:0045859 232 0.012
regulation of ossification GO:0030278 112 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
epithelial cell proliferation GO:0050673 174 0.012
heart morphogenesis GO:0003007 178 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
mesenchyme development GO:0060485 152 0.012
regulation of cell adhesion GO:0030155 154 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
negative regulation of cell development GO:0010721 169 0.012
response to radiation GO:0009314 165 0.012
rho protein signal transduction GO:0007266 32 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
nuclear transport GO:0051169 139 0.012
microtubule based process GO:0007017 236 0.012
negative regulation of molecular function GO:0044092 258 0.012
tissue remodeling GO:0048771 102 0.012
learning or memory GO:0007611 148 0.012
regulation of feeding behavior GO:0060259 3 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
muscle system process GO:0003012 141 0.012
regulation of serotonin secretion GO:0014062 3 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
regulation of transmembrane transport GO:0034762 128 0.012
spermatid development GO:0007286 108 0.012
wnt signaling pathway GO:0016055 188 0.012
aromatic compound catabolic process GO:0019439 286 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
cell fate commitment GO:0045165 210 0.012
cell maturation GO:0048469 127 0.011
angiogenesis GO:0001525 201 0.011
anatomical structure homeostasis GO:0060249 145 0.011
habituation GO:0046959 3 0.011
positive regulation of kinase activity GO:0033674 155 0.011
peptidyl amino acid modification GO:0018193 336 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
positive regulation of cytokine production GO:0001819 174 0.011
response to inorganic substance GO:0010035 96 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
cardiac muscle tissue development GO:0048738 130 0.011
response to light stimulus GO:0009416 135 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
leukocyte proliferation GO:0070661 172 0.011
homeostasis of number of cells GO:0048872 210 0.011
regulation of neuron death GO:1901214 134 0.011
protein targeting GO:0006605 143 0.011
t cell differentiation GO:0030217 174 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
purine nucleotide biosynthetic process GO:0006164 65 0.011
ribonucleotide biosynthetic process GO:0009260 59 0.011
organelle fission GO:0048285 170 0.011
telencephalon development GO:0021537 186 0.011
carboxylic acid transport GO:0046942 100 0.011
adult behavior GO:0030534 135 0.011
oocyte axis specification GO:0007309 2 0.011
peptide secretion GO:0002790 114 0.011
bone development GO:0060348 120 0.011
protein import GO:0017038 101 0.011
positive regulation of secretion GO:0051047 130 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
camp metabolic process GO:0046058 40 0.011
organ growth GO:0035265 117 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
fertilization GO:0009566 127 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
rhythmic process GO:0048511 174 0.011
cyclic nucleotide metabolic process GO:0009187 59 0.011
regulation of t cell proliferation GO:0042129 92 0.011
sequestering of calcium ion GO:0051208 18 0.011
response to nutrient levels GO:0031667 109 0.011
adaptive immune response GO:0002250 155 0.011
positive regulation of defense response GO:0031349 124 0.011
detection of stimulus GO:0051606 84 0.011
peptide transport GO:0015833 133 0.011
positive regulation of transferase activity GO:0051347 167 0.011
heterocycle catabolic process GO:0046700 280 0.010
cellular response to biotic stimulus GO:0071216 92 0.010
organic acid transport GO:0015849 101 0.010
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.010
endocytosis GO:0006897 168 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
sequestering of metal ion GO:0051238 19 0.010
regulation of vasculature development GO:1901342 88 0.010
neuron neuron synaptic transmission GO:0007270 69 0.010
pharynx development GO:0060465 1 0.010
retina development in camera type eye GO:0060041 119 0.010
response to amino acid GO:0043200 37 0.010
epithelial cell development GO:0002064 159 0.010
wound healing GO:0042060 157 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
neuron death GO:0070997 154 0.010
calcium ion transport GO:0006816 159 0.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.010
dna endoreduplication GO:0042023 4 0.010
spermatid differentiation GO:0048515 115 0.010
ribose phosphate biosynthetic process GO:0046390 59 0.010

Defb25 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
musculoskeletal system disease DOID:17 0 0.013
central nervous system disease DOID:331 0 0.012