Mus musculus

5 known processes

Bckdhb

branched chain ketoacid dehydrogenase E1, beta polypeptide

Bckdhb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
coenzyme metabolic process GO:0006732 52 0.419
cellular amino acid metabolic process GO:0006520 103 0.297
Human
carboxylic acid catabolic process GO:0046395 51 0.278
Human
cellular lipid metabolic process GO:0044255 323 0.167
small molecule catabolic process GO:0044282 71 0.136
Human
nucleobase containing small molecule metabolic process GO:0055086 352 0.128
cellular ketone metabolic process GO:0042180 84 0.109
organic acid catabolic process GO:0016054 51 0.100
Human
purine ribonucleotide metabolic process GO:0009150 290 0.090
nucleoside phosphate metabolic process GO:0006753 338 0.086
cellular modified amino acid metabolic process GO:0006575 63 0.076
monocarboxylic acid metabolic process GO:0032787 191 0.070
purine nucleoside metabolic process GO:0042278 241 0.068
acyl coa metabolic process GO:0006637 19 0.061
glycosyl compound metabolic process GO:1901657 246 0.061
sulfur compound metabolic process GO:0006790 100 0.057
amine metabolic process GO:0009308 45 0.056
ribonucleoside metabolic process GO:0009119 245 0.055
regulation of cellular ketone metabolic process GO:0010565 66 0.054
fatty acid oxidation GO:0019395 28 0.053
alpha amino acid metabolic process GO:1901605 59 0.053
generation of precursor metabolites and energy GO:0006091 103 0.052
oxidation reduction process GO:0055114 342 0.052
nucleoside metabolic process GO:0009116 246 0.047
mitochondrion organization GO:0007005 134 0.044
regulation of membrane potential GO:0042391 192 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
transmembrane transport GO:0055085 412 0.043
thioester metabolic process GO:0035383 19 0.042
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.041
negative regulation of cellular protein metabolic process GO:0032269 247 0.037
ribose phosphate metabolic process GO:0019693 291 0.035
cellular amine metabolic process GO:0044106 44 0.035
ribonucleoside triphosphate metabolic process GO:0009199 220 0.034
cell type specific apoptotic process GO:0097285 268 0.034
liver development GO:0001889 66 0.034
regulation of feeding behavior GO:0060259 3 0.034
glycerol ether metabolic process GO:0006662 2 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.033
regulation of organelle organization GO:0033043 289 0.033
organic cyclic compound catabolic process GO:1901361 295 0.033
cofactor metabolic process GO:0051186 80 0.032
alpha amino acid catabolic process GO:1901606 18 0.031
purine nucleotide metabolic process GO:0006163 302 0.031
nucleotide metabolic process GO:0009117 332 0.031
cellular amino acid catabolic process GO:0009063 25 0.030
Human
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
protein localization to organelle GO:0033365 185 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
purine containing compound metabolic process GO:0072521 311 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.028
hormone metabolic process GO:0042445 86 0.027
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
aromatic compound catabolic process GO:0019439 286 0.026
intrinsic apoptotic signaling pathway GO:0097193 132 0.026
protein processing GO:0016485 163 0.026
hepaticobiliary system development GO:0061008 67 0.026
apoptotic signaling pathway GO:0097190 306 0.025
organonitrogen compound catabolic process GO:1901565 264 0.025
Human
lipid catabolic process GO:0016042 69 0.025
response to molecule of bacterial origin GO:0002237 143 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.024
heterocycle catabolic process GO:0046700 280 0.024
fatty acid metabolic process GO:0006631 121 0.024
cellular lipid catabolic process GO:0044242 52 0.024
intracellular protein transport GO:0006886 204 0.024
dna metabolic process GO:0006259 303 0.023
ribonucleotide metabolic process GO:0009259 291 0.023
coenzyme biosynthetic process GO:0009108 23 0.023
regulation of cell activation GO:0050865 289 0.023
multicellular organismal signaling GO:0035637 91 0.023
neuron apoptotic process GO:0051402 142 0.023
transmission of nerve impulse GO:0019226 76 0.022
striated muscle tissue development GO:0014706 293 0.022
gland development GO:0048732 330 0.022
mitochondrial translation GO:0032543 4 0.022
neuronal action potential GO:0019228 54 0.022
action potential GO:0001508 78 0.022
homeostasis of number of cells GO:0048872 210 0.022
t cell activation GO:0042110 289 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
muscle cell differentiation GO:0042692 261 0.021
ether metabolic process GO:0018904 2 0.021
cofactor biosynthetic process GO:0051188 41 0.020
cytokine production GO:0001816 319 0.020
peptidyl amino acid modification GO:0018193 336 0.020
muscle tissue development GO:0060537 308 0.020
multicellular organism growth GO:0035264 161 0.020
urogenital system development GO:0001655 261 0.020
macromolecule catabolic process GO:0009057 281 0.020
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.019
membrane organization GO:0061024 245 0.019
regulation of hormone levels GO:0010817 211 0.019
lipid biosynthetic process GO:0008610 179 0.019
regulation of cytokine production GO:0001817 266 0.019
microtubule based process GO:0007017 236 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
defecation GO:0030421 1 0.018
positive regulation of protein modification process GO:0031401 299 0.018
acetyl coa biosynthetic process GO:0006085 5 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
myelination GO:0042552 74 0.018
renal system development GO:0072001 225 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
endocytosis GO:0006897 168 0.018
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
negative regulation of apoptotic signaling pathway GO:2001234 104 0.017
male gamete generation GO:0048232 285 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
spermatogenesis GO:0007283 284 0.017
mitochondrial transport GO:0006839 36 0.017
positive regulation of lymphocyte activation GO:0051251 140 0.016
purine nucleoside monophosphate metabolic process GO:0009126 81 0.016
immune effector process GO:0002252 321 0.016
positive regulation of cell activation GO:0050867 158 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
regulation of cellular catabolic process GO:0031329 242 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
cellular protein complex assembly GO:0043623 116 0.015
defense response to other organism GO:0098542 197 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
response to organonitrogen compound GO:0010243 246 0.015
Rat
establishment of protein localization to peroxisome GO:0072663 4 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
anion transport GO:0006820 177 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
small molecule biosynthetic process GO:0044283 132 0.015
leukocyte apoptotic process GO:0071887 71 0.015
peptide metabolic process GO:0006518 46 0.015
negative regulation of protein modification process GO:0031400 163 0.015
positive regulation of growth GO:0045927 104 0.015
response to lipopolysaccharide GO:0032496 128 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
maintenance of location GO:0051235 89 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
dicarboxylic acid metabolic process GO:0043648 18 0.014
myeloid cell differentiation GO:0030099 233 0.014
leukocyte homeostasis GO:0001776 79 0.014
response to inorganic substance GO:0010035 96 0.014
lipid modification GO:0030258 65 0.014
cytoplasmic transport GO:0016482 234 0.014
gonad development GO:0008406 141 0.014
monocarboxylic acid catabolic process GO:0072329 27 0.014
substantia nigra development GO:0021762 2 0.014
sulfur compound biosynthetic process GO:0044272 37 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
protein maturation GO:0051604 176 0.014
nucleoside phosphate biosynthetic process GO:1901293 79 0.014
ion transmembrane transport GO:0034220 361 0.014
regulation of protein localization GO:0032880 231 0.014
fat cell differentiation GO:0045444 160 0.014
regulation of kinase activity GO:0043549 249 0.013
positive regulation of cell development GO:0010720 237 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
organic acid biosynthetic process GO:0016053 86 0.013
development of primary sexual characteristics GO:0045137 143 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.013
fatty acid beta oxidation GO:0006635 16 0.013
lymphocyte homeostasis GO:0002260 64 0.013
negative regulation of immune system process GO:0002683 209 0.013
leukocyte differentiation GO:0002521 342 0.013
mapk cascade GO:0000165 281 0.013
regulation of transferase activity GO:0051338 263 0.013
cardiac muscle tissue development GO:0048738 130 0.013
ensheathment of neurons GO:0007272 76 0.013
organophosphate catabolic process GO:0046434 232 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
neuron death GO:0070997 154 0.013
kidney development GO:0001822 213 0.013
anatomical structure homeostasis GO:0060249 145 0.013
regulation of protein kinase activity GO:0045859 232 0.012
cation transport GO:0006812 399 0.012
ketone catabolic process GO:0042182 3 0.012
regulation of secretion by cell GO:1903530 249 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
positive regulation of glycolytic process GO:0045821 4 0.012
positive regulation of organelle organization GO:0010638 128 0.012
innate immune response GO:0045087 157 0.012
protein oligomerization GO:0051259 67 0.012
male gonad development GO:0008584 88 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
protein targeting GO:0006605 143 0.012
lymphocyte proliferation GO:0046651 164 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
tissue homeostasis GO:0001894 115 0.012
methylation GO:0032259 134 0.012
locomotory behavior GO:0007626 195 0.012
response to oxidative stress GO:0006979 123 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
lymphocyte differentiation GO:0030098 242 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
ribonucleotide biosynthetic process GO:0009260 59 0.012
translation GO:0006412 93 0.012
response to oxygen levels GO:0070482 62 0.012
cation transmembrane transport GO:0098655 266 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
negative regulation of molecular function GO:0044092 258 0.011
sensory perception GO:0007600 245 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
regulation of neuron death GO:1901214 134 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
gtp catabolic process GO:0006184 143 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
regulation of t cell activation GO:0050863 170 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
positive regulation of t cell activation GO:0050870 101 0.011
skeletal system development GO:0001501 356 0.011
response to testosterone GO:0033574 3 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
lipid localization GO:0010876 126 0.011
positive regulation of cell death GO:0010942 224 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
purine containing compound catabolic process GO:0072523 213 0.011
atp metabolic process GO:0046034 75 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
t cell differentiation GO:0030217 174 0.011
epithelial cell development GO:0002064 159 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
circulatory system process GO:0003013 197 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
connective tissue development GO:0061448 179 0.011
heart morphogenesis GO:0003007 178 0.011
cell proliferation in hindbrain GO:0021534 10 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
cellular protein catabolic process GO:0044257 155 0.010
protein localization to membrane GO:0072657 108 0.010
immune response activating signal transduction GO:0002757 116 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
endomembrane system organization GO:0010256 147 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
lymphocyte apoptotic process GO:0070227 54 0.010
bone development GO:0060348 120 0.010
regulation of homeostatic process GO:0032844 182 0.010
histone modification GO:0016570 159 0.010
glutamine family amino acid biosynthetic process GO:0009084 2 0.010
regulation of lymphocyte proliferation GO:0050670 117 0.010
negative regulation of organelle organization GO:0010639 90 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
guanosine containing compound catabolic process GO:1901069 144 0.010
protein import GO:0017038 101 0.010
lung development GO:0030324 164 0.010

Bckdhb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.667
Human
amino acid metabolic disorder DOID:9252 0 0.667
Human
inherited metabolic disorder DOID:655 0 0.667
Human
organic acidemia DOID:0060159 0 0.125
Human
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
sensory system disease DOID:0050155 0 0.022
eye and adnexa disease DOID:1492 0 0.022
eye disease DOID:5614 0 0.022
central nervous system disease DOID:331 0 0.014