Mus musculus

54 known processes

Cdk1

cyclin-dependent kinase 1

(Aliases: p34<CDC2>,Cdc2,Cdc2a)

Cdk1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
histone serine phosphorylation GO:0035404 5 0.998
spindle assembly involved in mitosis GO:0090307 4 0.998
histone phosphorylation GO:0016572 9 0.997
Rat
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.996
meiosis i GO:0007127 60 0.996
Yeast
regulation of spindle organization GO:0090224 2 0.995
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.993
chromosome segregation GO:0007059 48 0.993
Yeast
dna metabolic process GO:0006259 303 0.993
Yeast Mouse Rat
meiotic cell cycle process GO:1903046 77 0.992
Yeast
microtubule depolymerization GO:0007019 15 0.990
cell cycle comprising mitosis without cytokinesis GO:0033301 1 0.988
chromatin modification GO:0016568 187 0.987
Yeast Rat
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.984
mitotic cytokinesis GO:0000281 4 0.982
cellular protein catabolic process GO:0044257 155 0.980
female meiosis i GO:0007144 7 0.974
spindle midzone assembly GO:0051255 1 0.973
regulation of microtubule depolymerization GO:0031114 13 0.968
spindle assembly involved in meiosis GO:0090306 4 0.966
regulation of mitotic spindle organization GO:0060236 2 0.965
nuclear division GO:0000280 158 0.961
Yeast Worm Fly
regulation of exit from mitosis GO:0007096 1 0.954
negative regulation of microtubule depolymerization GO:0007026 13 0.952
microtubule cytoskeleton organization GO:0000226 157 0.950
Yeast
dna packaging GO:0006323 30 0.944
Rat
ubiquitin dependent protein catabolic process GO:0006511 129 0.943
spindle assembly involved in female meiosis GO:0007056 3 0.941
cellular response to dna damage stimulus GO:0006974 207 0.936
microtubule based movement GO:0007018 84 0.935
mitotic cell cycle process GO:1903047 159 0.931
mitotic nuclear division GO:0007067 48 0.928
Worm
female meiotic division GO:0007143 21 0.927
modification dependent protein catabolic process GO:0019941 133 0.926
organelle assembly GO:0070925 177 0.926
dna replication GO:0006260 52 0.925
Yeast Mouse Rat
meiotic nuclear division GO:0007126 115 0.922
Yeast Worm Fly
dna conformation change GO:0071103 37 0.921
Rat
chromosome condensation GO:0030261 10 0.920
Rat
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.919
spindle assembly GO:0051225 13 0.908
oocyte maturation GO:0001556 18 0.907
Worm
protein depolymerization GO:0051261 34 0.904
cytokinesis GO:0000910 17 0.903
cytokinetic process GO:0032506 2 0.899
protein catabolic process GO:0030163 221 0.896
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.892
mitotic centrosome separation GO:0007100 4 0.886
regulation of cellular protein catabolic process GO:1903362 61 0.882
chromatin organization GO:0006325 206 0.881
Yeast Rat
mitotic cell cycle GO:0000278 195 0.878
chromosome movement towards spindle pole GO:0051305 3 0.875
meiotic cell cycle GO:0051321 122 0.874
Yeast Worm Fly
cyclin catabolic process GO:0008054 1 0.873
mitotic cell cycle embryonic GO:0045448 5 0.870
negative regulation of cellular component organization GO:0051129 194 0.864
Yeast
positive regulation of protein phosphorylation GO:0001934 242 0.863
Worm
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.859
modification dependent macromolecule catabolic process GO:0043632 133 0.859
regulation of mitotic sister chromatid segregation GO:0033047 12 0.857
regulation of ubiquitin protein transferase activity GO:0051438 7 0.856
mitotic sister chromatid segregation GO:0000070 14 0.841
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.839
meiotic cytokinesis GO:0033206 5 0.838
regulation of proteasomal protein catabolic process GO:0061136 46 0.833
negative regulation of protein depolymerization GO:1901880 21 0.832
microtubule based process GO:0007017 236 0.829
Yeast
mitotic spindle assembly checkpoint GO:0007094 7 0.828
covalent chromatin modification GO:0016569 163 0.821
Rat
regulation of cell cycle process GO:0010564 160 0.814
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.804
negative regulation of cell cycle GO:0045786 123 0.801
metaphase plate congression GO:0051310 2 0.798
microtubule polymerization or depolymerization GO:0031109 26 0.794
germ cell development GO:0007281 185 0.792
Worm Fly
dephosphorylation GO:0016311 129 0.788
proteasomal protein catabolic process GO:0010498 98 0.786
cellular macromolecule catabolic process GO:0044265 206 0.781
Yeast
mitotic chromosome condensation GO:0007076 1 0.779
cell division GO:0051301 120 0.776
Yeast Worm Fly
regulation of protein complex disassembly GO:0043244 28 0.772
regulation of chromosome segregation GO:0051983 21 0.758
Yeast
positive regulation of chromosome segregation GO:0051984 4 0.744
organelle fission GO:0048285 170 0.739
Yeast Worm Fly
negative regulation of cellular protein catabolic process GO:1903363 22 0.726
negative regulation of mitotic cell cycle GO:0045930 58 0.725
peptidyl serine phosphorylation GO:0018105 74 0.722
Human Yeast
cleavage furrow formation GO:0036089 2 0.717
spindle assembly involved in female meiosis i GO:0007057 2 0.704
response to iron ion GO:0010039 4 0.701
positive regulation of dna replication GO:0045740 9 0.701
Yeast Mouse Rat
regulation of cell division GO:0051302 76 0.699
Yeast Worm
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.688
regulation of mitotic cell cycle GO:0007346 126 0.684
regulation of cellular catabolic process GO:0031329 242 0.672
Yeast
spindle checkpoint GO:0031577 12 0.671
attachment of spindle microtubules to kinetochore GO:0008608 4 0.644
regulation of protein depolymerization GO:1901879 26 0.643
negative regulation of sister chromatid segregation GO:0033046 7 0.636
mitotic cell cycle checkpoint GO:0007093 31 0.631
positive regulation of cell cycle GO:0045787 92 0.628
Yeast Rat Worm
regulation of cell cycle GO:0051726 281 0.617
regulation of chromosome organization GO:0033044 83 0.608
Yeast
protein complex disassembly GO:0043241 40 0.602
meiotic spindle organization GO:0000212 9 0.601
macromolecule catabolic process GO:0009057 281 0.600
Yeast
peptidyl amino acid modification GO:0018193 336 0.599
Human Yeast
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.593
organelle localization GO:0051640 179 0.589
Worm
regulation of protein kinase activity GO:0045859 232 0.585
Worm
asymmetric neuroblast division GO:0055059 1 0.582
Fly
macromolecular complex disassembly GO:0032984 43 0.572
heterocycle catabolic process GO:0046700 280 0.569
Yeast
regulation of microtubule based process GO:0032886 52 0.562
Yeast
leukocyte homeostasis GO:0001776 79 0.551
peptidyl serine modification GO:0018209 83 0.551
Human Yeast
spindle organization GO:0007051 28 0.539
positive regulation of meiotic cell cycle GO:0051446 15 0.532
Yeast Worm
positive regulation of mitotic cell cycle GO:0045931 41 0.527
Yeast Rat
regulation of proteolysis GO:0030162 164 0.527
gene silencing GO:0016458 38 0.514
regulation of cell cycle phase transition GO:1901987 77 0.507
dna replication independent nucleosome assembly GO:0006336 1 0.495
cellular protein complex disassembly GO:0043624 36 0.475
negative regulation of mitotic metaphase anaphase transition GO:0045841 7 0.472
astral microtubule organization GO:0030953 3 0.458
histone modification GO:0016570 159 0.451
Rat
negative regulation of cell cycle process GO:0010948 69 0.448
cell cycle checkpoint GO:0000075 47 0.446
positive regulation of exit from mitosis GO:0031536 1 0.442
regulation of microtubule cytoskeleton organization GO:0070507 37 0.434
Yeast
positive regulation of nfat protein import into nucleus GO:0051533 1 0.433
positive regulation of cellular catabolic process GO:0031331 148 0.426
Yeast
regulation of transferase activity GO:0051338 263 0.421
Worm
sister chromatid segregation GO:0000819 20 0.411
chromosome separation GO:0051304 14 0.410
asymmetric stem cell division GO:0098722 3 0.408
Fly
regulation of cytokinesis GO:0032465 5 0.407
negative regulation of protein complex disassembly GO:0043242 22 0.397
oocyte differentiation GO:0009994 35 0.396
Worm
establishment of organelle localization GO:0051656 122 0.395
Worm
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.384
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.383
positive regulation of fibroblast proliferation GO:0048146 20 0.381
mitotic sister chromatid separation GO:0051306 9 0.378
regulation of protein maturation GO:1903317 96 0.375
t cell homeostasis GO:0043029 35 0.374
negative regulation of phosphorus metabolic process GO:0010563 184 0.371
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.371
development of primary sexual characteristics GO:0045137 143 0.360
Worm
mitotic spindle organization GO:0007052 10 0.349
translesion synthesis GO:0019985 1 0.345
centrosome separation GO:0051299 4 0.345
regulation of protein localization GO:0032880 231 0.338
Yeast Rat Fly
regulation of mitotic metaphase anaphase transition GO:0030071 8 0.335
chromosome organization involved in meiosis GO:0070192 39 0.334
Yeast
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.333
negative regulation of cytoskeleton organization GO:0051494 36 0.327
developmental maturation GO:0021700 193 0.320
Worm
negative regulation of proteolysis GO:0045861 74 0.319
positive regulation of organelle organization GO:0010638 128 0.314
Yeast Worm
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.310
lymphocyte homeostasis GO:0002260 64 0.309
negative regulation of organelle organization GO:0010639 90 0.303
Yeast
cellular nitrogen compound catabolic process GO:0044270 280 0.301
Yeast
ventricular cardiac muscle cell development GO:0055015 11 0.300
Rat
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.299
g1 s transition of mitotic cell cycle GO:0000082 57 0.297
Mouse Fly
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.295
regulation of protein serine threonine kinase activity GO:0071900 157 0.281
Worm
regulation of protein processing GO:0070613 96 0.279
mitotic spindle checkpoint GO:0071174 9 0.279
fertilization GO:0009566 127 0.276
Worm
synaptonemal complex organization GO:0070193 15 0.272
Yeast
regulation of metaphase anaphase transition of cell cycle GO:1902099 9 0.272
regulation of intracellular protein transport GO:0033157 82 0.268
Rat
small gtpase mediated signal transduction GO:0007264 97 0.265
regulation of organelle organization GO:0033043 289 0.259
Yeast Worm
mrna metabolic process GO:0016071 84 0.257
Yeast
positive regulation of cellular protein catabolic process GO:1903364 34 0.257
protein modification by small protein conjugation or removal GO:0070647 207 0.252
establishment of chromosome localization GO:0051303 6 0.242
centrosome duplication GO:0051298 16 0.242
positive regulation of heart growth GO:0060421 18 0.240
Rat
positive regulation of chromosome organization GO:2001252 33 0.238
ras protein signal transduction GO:0007265 77 0.237
negative regulation of cellular catabolic process GO:0031330 47 0.235
protein ubiquitination GO:0016567 171 0.234
negative regulation of phosphate metabolic process GO:0045936 184 0.232
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.228
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.227
female gamete generation GO:0007292 74 0.227
Worm Fly
negative regulation of cell cycle phase transition GO:1901988 48 0.221
oocyte development GO:0048599 33 0.220
Worm
negative regulation of cellular protein metabolic process GO:0032269 247 0.218
histone h3 s10 phosphorylation GO:0043987 1 0.216
centrosome cycle GO:0007098 23 0.216
negative regulation of mitosis GO:0045839 10 0.215
positive regulation of cell division GO:0051781 31 0.213
Worm
positive regulation of mitosis GO:0045840 14 0.212
positive regulation of protein modification process GO:0031401 299 0.210
Worm
nucleoside phosphate catabolic process GO:1901292 222 0.208
microtubule anchoring GO:0034453 9 0.205
homeostasis of number of cells GO:0048872 210 0.202
striated muscle cell proliferation GO:0014855 39 0.201
Rat
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 2 0.190
mrna processing GO:0006397 63 0.189
Yeast
regulation of kinase activity GO:0043549 249 0.188
Worm
endocytosis GO:0006897 168 0.186
neuron migration GO:0001764 122 0.185
regulation of dephosphorylation GO:0035303 18 0.183
mrna 3 end processing GO:0031124 16 0.183
neural tube development GO:0021915 160 0.181
maintenance of location GO:0051235 89 0.181
regulation of embryonic development GO:0045995 71 0.179
dendrite development GO:0016358 115 0.178
genitalia development GO:0048806 37 0.176
Worm
female meiosis chromosome segregation GO:0016321 1 0.175
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.174
dna integrity checkpoint GO:0031570 28 0.174
negative regulation of protein maturation GO:1903318 79 0.172
cell cycle g2 m phase transition GO:0044839 20 0.167
Fly
negative regulation of chromosome organization GO:2001251 30 0.164
Yeast
positive regulation of protein kinase activity GO:0045860 144 0.158
Worm
single fertilization GO:0007338 82 0.157
Worm
peptidyl threonine phosphorylation GO:0018107 31 0.157
Human
protein maturation GO:0051604 176 0.156
regulation of mitotic cell cycle phase transition GO:1901990 73 0.155
positive regulation of chromatin modification GO:1903310 28 0.155
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 9 0.152
protein localization to nucleus GO:0034504 121 0.151
Rat
fibroblast proliferation GO:0048144 35 0.150
nuclear transport GO:0051169 139 0.149
Rat
negative regulation of protein processing GO:0010955 79 0.149
regulation of cellular ketone metabolic process GO:0010565 66 0.148
regulation of cytoskeleton organization GO:0051493 122 0.148
Yeast
activation of anaphase promoting complex activity GO:0051488 1 0.141
type b pancreatic cell proliferation GO:0044342 10 0.140
protein processing GO:0016485 163 0.137
protein modification by small protein conjugation GO:0032446 187 0.135
male meiosis GO:0007140 37 0.132
Fly
negative regulation of protein metabolic process GO:0051248 282 0.130
regulation of nuclear division GO:0051783 56 0.128
Worm
protein dna complex subunit organization GO:0071824 28 0.126
regulation of mitosis GO:0007088 29 0.126
meiotic chromosome segregation GO:0045132 19 0.125
meiosis ii GO:0007135 7 0.123
organic cyclic compound catabolic process GO:1901361 295 0.122
Yeast
negative regulation of gene expression epigenetic GO:0045814 15 0.121
lateral inhibition GO:0046331 1 0.115
dna ligation GO:0006266 3 0.115
regulation of meiotic cell cycle GO:0051445 34 0.115
Yeast Worm
male gamete generation GO:0048232 285 0.114
Fly
protein localization to chromosome GO:0034502 6 0.113
Human
aromatic compound catabolic process GO:0019439 286 0.112
Yeast
negative regulation of mitotic sister chromatid separation GO:2000816 7 0.112
nucleotide metabolic process GO:0009117 332 0.112
purine ribonucleotide metabolic process GO:0009150 290 0.111
cardiac muscle tissue growth GO:0055017 37 0.110
Rat
negative regulation of protein modification process GO:0031400 163 0.109
dna endoreduplication GO:0042023 4 0.106
negative regulation of phosphorylation GO:0042326 166 0.105
negative regulation of protein dephosphorylation GO:0035308 2 0.105
regulation of mrna metabolic process GO:1903311 43 0.104
neural tube formation GO:0001841 108 0.103
regulation of cardiac muscle tissue development GO:0055024 31 0.100
Rat
regulation of dna replication GO:0006275 17 0.099
Yeast Mouse Rat
dna dependent dna replication GO:0006261 24 0.099
Yeast Mouse
establishment or maintenance of cell polarity GO:0007163 86 0.099
regulation of fibroblast proliferation GO:0048145 34 0.099
response to organic cyclic compound GO:0014070 198 0.098
Rat
regulation of nucleocytoplasmic transport GO:0046822 73 0.098
Rat
negative regulation of protein phosphorylation GO:0001933 126 0.094
body morphogenesis GO:0010171 45 0.094
ribose phosphate metabolic process GO:0019693 291 0.092
embryonic epithelial tube formation GO:0001838 130 0.089
cardiac muscle tissue development GO:0048738 130 0.089
Rat
cellular homeostasis GO:0019725 240 0.088
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.088
muscle cell differentiation GO:0042692 261 0.087
Rat
muscle tissue development GO:0060537 308 0.087
Rat
axonogenesis GO:0007409 274 0.086
purine nucleotide metabolic process GO:0006163 302 0.086
digestive system development GO:0055123 200 0.086
purine ribonucleoside catabolic process GO:0046130 205 0.086
positive regulation of nervous system development GO:0051962 221 0.085
nucleoside phosphate metabolic process GO:0006753 338 0.085
positive regulation of mrna 3 end processing GO:0031442 5 0.085
regulation of cellular amino acid metabolic process GO:0006521 5 0.084
cellular response to lipid GO:0071396 145 0.084
cardiocyte differentiation GO:0035051 87 0.083
Rat
ribonucleoside metabolic process GO:0009119 245 0.082
single organism nuclear import GO:1902593 95 0.082
Rat
positive regulation of cellular amine metabolic process GO:0033240 5 0.082
multicellular organismal reproductive behavior GO:0033057 23 0.082
ribonucleotide metabolic process GO:0009259 291 0.081
response to oxidative stress GO:0006979 123 0.081
Rat
cardiac muscle cell development GO:0055013 39 0.080
Rat
regulation of dna dependent dna replication GO:0090329 8 0.079
Yeast Mouse
regulation of binding GO:0051098 111 0.079
rna processing GO:0006396 105 0.078
Yeast
negative regulation of mitotic sister chromatid segregation GO:0033048 7 0.077
chromatin assembly or disassembly GO:0006333 16 0.077
protein localization to organelle GO:0033365 185 0.076
Human Rat
regulation of cell projection organization GO:0031344 206 0.076
organ growth GO:0035265 117 0.076
Rat
response to uv GO:0009411 44 0.075
positive regulation of cell cycle process GO:0090068 61 0.072
Yeast Worm
cellular chemical homeostasis GO:0055082 215 0.072
regulation of protein catabolic process GO:0042176 108 0.072
ribonucleoside catabolic process GO:0042454 206 0.072
heart growth GO:0060419 45 0.071
Rat
ventricular cardiac muscle cell differentiation GO:0055012 17 0.071
Rat
positive regulation of transferase activity GO:0051347 167 0.070
Worm
intracellular protein transport GO:0006886 204 0.069
Rat
thymus development GO:0048538 41 0.069
cytoplasmic transport GO:0016482 234 0.069
Rat
response to inorganic substance GO:0010035 96 0.068
Rat
gland development GO:0048732 330 0.068
endomembrane system organization GO:0010256 147 0.067
protein localization to chromosome centromeric region GO:0071459 1 0.067
Human
cell cycle switching GO:0060184 1 0.066
exit from mitosis GO:0010458 3 0.065
oxidation reduction process GO:0055114 342 0.065
regulation of sister chromatid cohesion GO:0007063 5 0.065
Yeast
spindle localization GO:0051653 22 0.064
protein targeting GO:0006605 143 0.064
Rat
regulation of protein dephosphorylation GO:0035304 4 0.063
regeneration GO:0031099 38 0.063
Rat
cell type specific apoptotic process GO:0097285 268 0.063
synaptonemal complex assembly GO:0007130 13 0.063
Yeast
regulation of mitotic sister chromatid separation GO:0010965 12 0.063
stem cell differentiation GO:0048863 268 0.062
regulation of cellular amine metabolic process GO:0033238 20 0.061
response to oxygen levels GO:0070482 62 0.061
cellular ketone metabolic process GO:0042180 84 0.061
sister chromatid cohesion GO:0007062 12 0.060
Yeast
purine ribonucleoside metabolic process GO:0046128 241 0.060
multi organism behavior GO:0051705 62 0.060
regulation of meiosis i GO:0060631 7 0.059
cellular response to organic cyclic compound GO:0071407 87 0.059
negative regulation of meiotic cell cycle GO:0051447 14 0.058
Yeast
regulation of mapk cascade GO:0043408 248 0.058
negative regulation of nuclear division GO:0051784 19 0.058
regulation of ras protein signal transduction GO:0046578 114 0.058
ribonucleoside triphosphate metabolic process GO:0009199 220 0.058
multi multicellular organism process GO:0044706 109 0.057
purine containing compound metabolic process GO:0072521 311 0.057
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.057
wnt signaling pathway GO:0016055 188 0.056
regulation of protein targeting GO:1903533 61 0.055
Rat
mapk cascade GO:0000165 281 0.055
positive regulation of cell cycle phase transition GO:1901989 17 0.055
regulation of organ growth GO:0046620 61 0.053
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.053
positive regulation of mitotic metaphase anaphase transition GO:0045842 2 0.053
oogenesis GO:0048477 56 0.052
Worm Fly
regulation of protein import into nucleus GO:0042306 52 0.052
Rat
cell fate commitment GO:0045165 210 0.052
Fly
chromosome localization GO:0050000 8 0.052
stem cell development GO:0048864 219 0.051
regulation of ligase activity GO:0051340 10 0.051
cellular response to hormone stimulus GO:0032870 150 0.049
cell maturation GO:0048469 127 0.049
Worm
protein import GO:0017038 101 0.049
Rat
negative regulation of cell division GO:0051782 24 0.049
positive regulation of histone modification GO:0031058 28 0.049
regulation of purine nucleotide metabolic process GO:1900542 169 0.048
amine metabolic process GO:0009308 45 0.048
guanosine containing compound metabolic process GO:1901068 144 0.048
negative regulation of protein catabolic process GO:0042177 36 0.048
negative regulation of chromosome segregation GO:0051985 9 0.047
Yeast
regulation of synaptic plasticity GO:0048167 87 0.047
nucleoside triphosphate metabolic process GO:0009141 230 0.047
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.046
forebrain development GO:0030900 302 0.046
regulation of chromatin silencing GO:0031935 2 0.046
positive regulation of attachment of spindle microtubules to kinetochore GO:0051987 2 0.046
cell fate determination GO:0001709 32 0.045
regulation of nucleoside metabolic process GO:0009118 130 0.045
regulation of secretion GO:0051046 274 0.045
striated muscle cell development GO:0055002 125 0.045
Rat
positive regulation of intracellular protein transport GO:0090316 42 0.045
Rat
positive regulation of intracellular transport GO:0032388 70 0.045
Rat
regulation of cellular response to stress GO:0080135 159 0.044
Yeast
regulation of protein transport GO:0051223 163 0.044
Rat
stem cell maintenance GO:0019827 130 0.043
posttranscriptional regulation of gene expression GO:0010608 155 0.043
reproductive behavior GO:0019098 32 0.043
digestive tract development GO:0048565 190 0.042
neural tube closure GO:0001843 90 0.042
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 8 0.042
negative regulation of molecular function GO:0044092 258 0.042
regulation of mrna processing GO:0050684 41 0.042
positive regulation of nuclear division GO:0051785 27 0.041
Worm
cardiac cell development GO:0055006 41 0.040
Rat
peptidyl threonine modification GO:0018210 31 0.040
Human
regulation of glycogen catabolic process GO:0005981 2 0.040
response to cell cycle checkpoint signaling GO:0072396 1 0.040
chromatin silencing GO:0006342 15 0.039
cellular amino acid metabolic process GO:0006520 103 0.039
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.039
Rat
response to drug GO:0042493 75 0.038
Rat
cellular amine metabolic process GO:0044106 44 0.038
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.038
chromatin remodeling GO:0006338 32 0.038
Yeast
nucleocytoplasmic transport GO:0006913 139 0.038
Rat
regulation of muscle tissue development GO:1901861 97 0.038
Rat
nucleoside triphosphate catabolic process GO:0009143 205 0.037
purine containing compound catabolic process GO:0072523 213 0.037
regulation of neuron projection development GO:0010975 169 0.037
regulation of chromatin modification GO:1903308 57 0.037
purine nucleoside triphosphate metabolic process GO:0009144 226 0.037
dna recombination GO:0006310 92 0.036
Yeast
hematopoietic progenitor cell differentiation GO:0002244 143 0.036
cellular response to acid chemical GO:0071229 68 0.036
cellular response to inorganic substance GO:0071241 37 0.036
positive regulation of protein catabolic process GO:0045732 60 0.036
muscle cell development GO:0055001 133 0.035
Rat
regulation of secretion by cell GO:1903530 249 0.035
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
positive regulation of nucleotide metabolic process GO:0045981 114 0.035
reciprocal meiotic recombination GO:0007131 16 0.034
rho protein signal transduction GO:0007266 32 0.033
cellular response to radiation GO:0071478 28 0.033
positive regulation of gtp catabolic process GO:0033126 85 0.033
organonitrogen compound catabolic process GO:1901565 264 0.033
nuclear import GO:0051170 95 0.033
Rat
nucleoside catabolic process GO:0009164 206 0.033
positive regulation of organ growth GO:0046622 29 0.032
Rat
regulation of cell motility GO:2000145 236 0.032
regulation of defense response GO:0031347 233 0.032
regulation of establishment of protein localization GO:0070201 181 0.032
Rat
digestive tract morphogenesis GO:0048546 147 0.032
regulation of chromatin organization GO:1902275 57 0.032
response to decreased oxygen levels GO:0036293 59 0.032
positive regulation of protein localization to nucleus GO:1900182 30 0.032
Rat
purine nucleoside catabolic process GO:0006152 205 0.031
regulation of histone modification GO:0031056 56 0.031
histone acetylation GO:0016573 41 0.031
generation of precursor metabolites and energy GO:0006091 103 0.031
regulation of neuron differentiation GO:0045664 281 0.030
spindle assembly checkpoint GO:0071173 9 0.030
response to acid chemical GO:0001101 111 0.030
establishment of protein localization to organelle GO:0072594 118 0.030
Rat
positive regulation of kinase activity GO:0033674 155 0.029
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
purine nucleotide catabolic process GO:0006195 211 0.029
cellular response to metal ion GO:0071248 31 0.029
regulation of sister chromatid segregation GO:0033045 13 0.029
protein import into nucleus GO:0006606 95 0.029
Rat
cellular response to hexose stimulus GO:0071331 47 0.029
cell cycle g1 s phase transition GO:0044843 57 0.028
Mouse Fly
positive regulation of synaptic plasticity GO:0031915 4 0.028
blastocyst development GO:0001824 80 0.028
regulation of dna recombination GO:0000018 34 0.028
Yeast
membrane organization GO:0061024 245 0.028
multi organism reproductive behavior GO:0044705 29 0.027
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.027
ribonucleotide catabolic process GO:0009261 208 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.027
regulation of purine nucleotide catabolic process GO:0033121 122 0.027
regulation of nucleotide catabolic process GO:0030811 122 0.027
negative regulation of dephosphorylation GO:0035305 9 0.027
synaptic transmission GO:0007268 329 0.026
muscle cell proliferation GO:0033002 52 0.026
Rat
regulation of cardiac muscle cell proliferation GO:0060043 23 0.026
Rat
carbohydrate metabolic process GO:0005975 230 0.026
centrosome organization GO:0051297 26 0.025
positive regulation of oocyte maturation GO:1900195 2 0.025
purine nucleoside monophosphate catabolic process GO:0009128 58 0.025
energy derivation by oxidation of organic compounds GO:0015980 77 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
regulation of mrna 3 end processing GO:0031440 6 0.025
microtubule nucleation GO:0007020 2 0.025
positive regulation of proteolysis GO:0045862 85 0.025
carbohydrate homeostasis GO:0033500 128 0.025
cellularization GO:0007349 1 0.025
positive regulation of viral genome replication GO:0045070 2 0.025
adult locomotory behavior GO:0008344 91 0.025
cdc42 protein signal transduction GO:0032488 0 0.025
myeloid cell differentiation GO:0030099 233 0.024
rna interference GO:0016246 2 0.024
nucleotide catabolic process GO:0009166 217 0.024
nuclear migration GO:0007097 6 0.024
Worm
apoptotic signaling pathway GO:0097190 306 0.024
atp metabolic process GO:0046034 75 0.024
organophosphate catabolic process GO:0046434 232 0.023
regulation of leukocyte differentiation GO:1902105 159 0.023
purine nucleoside triphosphate catabolic process GO:0009146 203 0.023
spermatogenesis GO:0007283 284 0.023
Fly
purine nucleoside metabolic process GO:0042278 241 0.023
regulation of cell cycle checkpoint GO:1901976 9 0.023
negative regulation of necrotic cell death GO:0060547 11 0.022

Cdk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 0 0.024
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.024