Mus musculus

105 known processes

Cdk2

cyclin-dependent kinase 2

(Aliases: A630093N05Rik)

Cdk2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle process GO:0010564 160 0.947
Yeast Mouse
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.938
regulation of exit from mitosis GO:0007096 1 0.903
dna metabolic process GO:0006259 303 0.892
dna replication GO:0006260 52 0.885
mitotic cell cycle GO:0000278 195 0.882
cellular response to dna damage stimulus GO:0006974 207 0.854
Yeast Mouse
dna endoreduplication GO:0042023 4 0.840
organ regeneration GO:0031100 2 0.837
Rat
ovarian follicle development GO:0001541 40 0.806
mitotic cell cycle process GO:1903047 159 0.802
regulation of mitotic cell cycle GO:0007346 126 0.799
Yeast Mouse
cell cycle g1 s phase transition GO:0044843 57 0.796
cell cycle switching GO:0060184 1 0.752
positive regulation of cell cycle GO:0045787 92 0.750
Yeast
negative regulation of cell cycle GO:0045786 123 0.737
Yeast Mouse
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.725
positive regulation of cell cycle process GO:0090068 61 0.689
Yeast
regulation of cell cycle GO:0051726 281 0.674
germ cell development GO:0007281 185 0.651
ovulation cycle GO:0042698 59 0.619
regulation of mitotic cell cycle phase transition GO:1901990 73 0.617
Mouse
organelle fission GO:0048285 170 0.602
Yeast
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.585
chromosome segregation GO:0007059 48 0.558
Yeast
gonad development GO:0008406 141 0.555
mitotic cell cycle arrest GO:0071850 4 0.552
asymmetric neuroblast division GO:0055059 1 0.550
regulation of dna replication GO:0006275 17 0.549
development of primary sexual characteristics GO:0045137 143 0.538
modification dependent macromolecule catabolic process GO:0043632 133 0.501
regulation of cellular catabolic process GO:0031329 242 0.489
Yeast
rhythmic process GO:0048511 174 0.480
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.471
Mouse
mitotic nuclear division GO:0007067 48 0.462
cellular protein catabolic process GO:0044257 155 0.459
dna replication initiation GO:0006270 5 0.455
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.453
heterocycle catabolic process GO:0046700 280 0.449
Yeast
negative regulation of mitotic cell cycle GO:0045930 58 0.443
Yeast Mouse
regulation of meiotic cell cycle GO:0051445 34 0.435
Yeast
spermatogenesis GO:0007283 284 0.432
regulation of mitosis GO:0007088 29 0.424
neuroblast differentiation GO:0014016 2 0.422
nuclear division GO:0000280 158 0.418
Yeast
negative regulation of protein metabolic process GO:0051248 282 0.414
neuroblast fate determination GO:0007400 1 0.407
response to transition metal nanoparticle GO:1990267 11 0.407
regulation of nuclear division GO:0051783 56 0.407
protein modification by small protein conjugation or removal GO:0070647 207 0.400
cellular macromolecule catabolic process GO:0044265 206 0.394
Yeast
g1 s transition of mitotic cell cycle GO:0000082 57 0.374
regulation of cellular response to stress GO:0080135 159 0.369
Yeast
positive regulation of cell cycle phase transition GO:1901989 17 0.364
positive regulation of apoptotic process GO:0043065 217 0.362
macromolecule catabolic process GO:0009057 281 0.362
Yeast
gene silencing GO:0016458 38 0.359
Human
mitotic cell cycle checkpoint GO:0007093 31 0.357
Mouse
dna repair GO:0006281 107 0.353
Yeast
positive regulation of meiotic cell cycle GO:0051446 15 0.352
Yeast
negative regulation of cell cycle phase transition GO:1901988 48 0.351
Mouse
regulation of cell cycle g1 s phase transition GO:1902806 35 0.349
cell cycle checkpoint GO:0000075 47 0.348
Mouse
regulation of protein kinase activity GO:0045859 232 0.347
ubiquitin dependent protein catabolic process GO:0006511 129 0.343
regulation of cellular protein catabolic process GO:1903362 61 0.340
meiotic cell cycle GO:0051321 122 0.331
Yeast
negative regulation of nuclear division GO:0051784 19 0.329
regulation of chromosome organization GO:0033044 83 0.327
Yeast
positive regulation of programmed cell death GO:0043068 218 0.322
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.320
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.316
small gtpase mediated signal transduction GO:0007264 97 0.313
Human
modification dependent protein catabolic process GO:0019941 133 0.303
mitotic sister chromatid segregation GO:0000070 14 0.294
regulation of proteasomal protein catabolic process GO:0061136 46 0.293
meiotic nuclear division GO:0007126 115 0.290
Yeast
negative regulation of cellular component organization GO:0051129 194 0.289
Yeast
proteasomal protein catabolic process GO:0010498 98 0.287
cell cycle arrest GO:0007050 37 0.285
wnt signaling pathway GO:0016055 188 0.282
protein processing GO:0016485 163 0.279
male gamete generation GO:0048232 285 0.279
regulation of kinase activity GO:0043549 249 0.278
negative regulation of cell cycle process GO:0010948 69 0.275
Yeast Mouse
protein maturation GO:0051604 176 0.275
positive regulation of mitotic cell cycle GO:0045931 41 0.274
Yeast
stem cell fate determination GO:0048867 2 0.270
negative regulation of organelle organization GO:0010639 90 0.266
Yeast
cell division GO:0051301 120 0.263
Yeast
positive regulation of cell cycle g1 s phase transition GO:1902808 9 0.263
positive regulation of cell death GO:0010942 224 0.262
regulation of cell cycle phase transition GO:1901987 77 0.260
Mouse
ras protein signal transduction GO:0007265 77 0.259
Human
regulation of metaphase anaphase transition of cell cycle GO:1902099 9 0.256
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.256
sister chromatid segregation GO:0000819 20 0.252
negative regulation of cellular protein metabolic process GO:0032269 247 0.250
regulation of transferase activity GO:0051338 263 0.245
negative regulation of protein modification process GO:0031400 163 0.228
stem cell maintenance GO:0019827 130 0.227
protein ubiquitination GO:0016567 171 0.226
regulation of mitotic sister chromatid segregation GO:0033047 12 0.226
apoptotic signaling pathway GO:0097190 306 0.225
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.223
genitalia development GO:0048806 37 0.219
regulation of organelle organization GO:0033043 289 0.219
Yeast
cell fate commitment GO:0045165 210 0.216
mitotic sister chromatid separation GO:0051306 9 0.214
response to organonitrogen compound GO:0010243 246 0.213
Rat
intrinsic apoptotic signaling pathway GO:0097193 132 0.212
asymmetric stem cell division GO:0098722 3 0.210
liver development GO:0001889 66 0.210
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.202
negative regulation of ligase activity GO:0051352 3 0.196
dna recombination GO:0006310 92 0.193
Yeast
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.192
hepaticobiliary system development GO:0061008 67 0.191
regulation of proteolysis GO:0030162 164 0.190
regulation of sister chromatid segregation GO:0033045 13 0.190
regulation of cell division GO:0051302 76 0.189
Yeast
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.186
stem cell differentiation GO:0048863 268 0.184
chromosome separation GO:0051304 14 0.183
protein modification by small protein conjugation GO:0032446 187 0.183
cellular nitrogen compound catabolic process GO:0044270 280 0.182
Yeast
negative regulation of transferase activity GO:0051348 85 0.178
negative regulation of cellular protein catabolic process GO:1903363 22 0.176
positive regulation of g1 s transition of mitotic cell cycle GO:1900087 9 0.174
chromatin organization GO:0006325 206 0.173
Human Yeast
exit from mitosis GO:0010458 3 0.170
protein catabolic process GO:0030163 221 0.170
negative regulation of chromosome organization GO:2001251 30 0.168
Yeast
regulation of chromosome segregation GO:0051983 21 0.167
Yeast
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.164
response to steroid hormone GO:0048545 56 0.162
Rat
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.162
neuroblast fate commitment GO:0014017 1 0.160
jak stat cascade GO:0007259 42 0.159
Fly
negative regulation of molecular function GO:0044092 258 0.159
organelle assembly GO:0070925 177 0.153
stem cell development GO:0048864 219 0.151
gland development GO:0048732 330 0.150
response to mineralocorticoid GO:0051385 1 0.148
negative regulation of cell division GO:0051782 24 0.148
regeneration GO:0031099 38 0.146
Rat
negative regulation of cellular catabolic process GO:0031330 47 0.140
response to ketone GO:1901654 15 0.140
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.136
regulation of ligase activity GO:0051340 10 0.135
regulation of ubiquitin protein transferase activity GO:0051438 7 0.134
stem cell proliferation GO:0072089 117 0.132
regulation of nuclear cell cycle dna replication GO:0033262 2 0.132
Yeast
male meiosis GO:0007140 37 0.131
response to drug GO:0042493 75 0.130
Rat
response to glucocorticoid GO:0051384 20 0.130
chromosome organization involved in meiosis GO:0070192 39 0.129
Yeast
dna dependent dna replication GO:0006261 24 0.129
development of primary female sexual characteristics GO:0046545 73 0.124
female sex differentiation GO:0046660 84 0.123
aromatic compound catabolic process GO:0019439 286 0.123
Yeast
somatic stem cell maintenance GO:0035019 47 0.121
positive regulation of protein phosphorylation GO:0001934 242 0.119
negative regulation of proteolysis GO:0045861 74 0.115
cellular response to external stimulus GO:0071496 88 0.112
response to corticosteroid GO:0031960 20 0.111
regulation of protein maturation GO:1903317 96 0.110
neural precursor cell proliferation GO:0061351 121 0.109
chromatin modification GO:0016568 187 0.109
Human Yeast
regulation of chromatin silencing GO:0031935 2 0.108
microtubule cytoskeleton organization GO:0000226 157 0.107
Yeast
recombinational repair GO:0000725 21 0.107
Yeast
response to estradiol GO:0032355 12 0.106
Rat
microtubule based process GO:0007017 236 0.102
Yeast
regulation of protein serine threonine kinase activity GO:0071900 157 0.102
response to estrogen GO:0043627 24 0.102
Rat
regulation of mitotic metaphase anaphase transition GO:0030071 8 0.102
regulation of protein processing GO:0070613 96 0.101
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.100
Yeast
myosin filament assembly GO:0031034 2 0.100
negative regulation of mitosis GO:0045839 10 0.100
negative regulation of cell cycle arrest GO:0071157 1 0.098
dna biosynthetic process GO:0071897 22 0.098
muscle cell differentiation GO:0042692 261 0.097
positive regulation of cellular catabolic process GO:0031331 148 0.097
Yeast
female gonad development GO:0008585 71 0.096
myosin filament organization GO:0031033 3 0.095
cellular response to nutrient levels GO:0031669 64 0.095
dna damage checkpoint GO:0000077 26 0.095
Mouse
cellular component assembly involved in morphogenesis GO:0010927 139 0.094
negative regulation of chromatin silencing GO:0031936 1 0.093
response to vitamin GO:0033273 6 0.092
negative regulation of protein maturation GO:1903318 79 0.088
response to nutrient levels GO:0031667 109 0.088
histone modification GO:0016570 159 0.087
Human
cytoplasmic transport GO:0016482 234 0.087
posttranscriptional regulation of gene expression GO:0010608 155 0.084
cation transport GO:0006812 399 0.083
single fertilization GO:0007338 82 0.082
regulation of cellular amino acid metabolic process GO:0006521 5 0.082
cellular ketone metabolic process GO:0042180 84 0.081
striated muscle myosin thick filament assembly GO:0071688 1 0.079
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.079
negative regulation of cell proliferation GO:0008285 296 0.079
meiotic chromosome segregation GO:0045132 19 0.078
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 9 0.078
response to endoplasmic reticulum stress GO:0034976 53 0.077
double strand break repair via homologous recombination GO:0000724 21 0.076
Yeast
muscle cell development GO:0055001 133 0.076
cellular response to extracellular stimulus GO:0031668 81 0.075
neural tube development GO:0021915 160 0.074
cell cycle g2 m phase transition GO:0044839 20 0.073
protein localization to organelle GO:0033365 185 0.071
synaptonemal complex organization GO:0070193 15 0.070
Yeast
cytokinesis GO:0000910 17 0.070
mitochondrion organization GO:0007005 134 0.070
cell cycle comprising mitosis without cytokinesis GO:0033301 1 0.069
regulation of cytoplasmic transport GO:1903649 112 0.069
response to organic cyclic compound GO:0014070 198 0.069
Rat
synaptonemal complex assembly GO:0007130 13 0.069
Yeast
body morphogenesis GO:0010171 45 0.068
cellular homeostasis GO:0019725 240 0.068
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.068
regulation of neuron differentiation GO:0045664 281 0.068
regulation of binding GO:0051098 111 0.066
multicellular organism growth GO:0035264 161 0.066
cell adhesion GO:0007155 329 0.065
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.064
response to radiation GO:0009314 165 0.064
negative regulation of mitotic metaphase anaphase transition GO:0045841 7 0.064
cellular amine metabolic process GO:0044106 44 0.063
covalent chromatin modification GO:0016569 163 0.062
Human
nucleobase containing small molecule metabolic process GO:0055086 352 0.062
mitotic g1 dna damage checkpoint GO:0031571 4 0.062
response to extracellular stimulus GO:0009991 127 0.061
cellular amino acid metabolic process GO:0006520 103 0.061
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.061
ribonucleoside metabolic process GO:0009119 245 0.059
positive regulation of protein modification process GO:0031401 299 0.059
positive regulation of kinase activity GO:0033674 155 0.059
purine ribonucleotide metabolic process GO:0009150 290 0.057
nucleocytoplasmic transport GO:0006913 139 0.057
purine ribonucleoside catabolic process GO:0046130 205 0.056
peripheral nervous system development GO:0007422 53 0.055
cellular lipid metabolic process GO:0044255 323 0.055
Yeast
negative regulation of phosphate metabolic process GO:0045936 184 0.055
chromosome condensation GO:0030261 10 0.055
cell fate determination GO:0001709 32 0.055
metaphase plate congression GO:0051310 2 0.055
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 5 0.053
leukocyte differentiation GO:0002521 342 0.053
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.053
nucleotide metabolic process GO:0009117 332 0.053
t cell proliferation GO:0042098 120 0.052
neuron fate specification GO:0048665 30 0.052
double strand break repair GO:0006302 48 0.051
Yeast
protein localization to nucleus GO:0034504 121 0.051
purine nucleotide metabolic process GO:0006163 302 0.050
meiotic cell cycle process GO:1903046 77 0.050
Yeast
regulation of nucleocytoplasmic transport GO:0046822 73 0.049
chromatin silencing GO:0006342 15 0.049
signal transduction by p53 class mediator GO:0072331 51 0.049
regulation of protein catabolic process GO:0042176 108 0.048
regulation of apoptotic signaling pathway GO:2001233 197 0.047
striated muscle cell development GO:0055002 125 0.046
regulation of double strand break repair via homologous recombination GO:0010569 2 0.045
Yeast
transmembrane transport GO:0055085 412 0.045
positive regulation of growth GO:0045927 104 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.045
protein targeting GO:0006605 143 0.045
negative regulation of mitotic sister chromatid segregation GO:0033048 7 0.044
cellular response to topologically incorrect protein GO:0035967 25 0.044
mapk cascade GO:0000165 281 0.044
membrane organization GO:0061024 245 0.043
negative regulation of phosphorus metabolic process GO:0010563 184 0.043
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.043
response to progesterone GO:0032570 1 0.043
regulation of muscle tissue development GO:1901861 97 0.042
protein polymerization GO:0051258 57 0.042
response to uv GO:0009411 44 0.042
actomyosin structure organization GO:0031032 56 0.042
negative regulation of phosphorylation GO:0042326 166 0.042
cell aging GO:0007569 35 0.042
nuclear transport GO:0051169 139 0.041
glycerolipid metabolic process GO:0046486 122 0.041
Yeast
positive regulation of protein kinase activity GO:0045860 144 0.041
translesion synthesis GO:0019985 1 0.041
neuroblast division GO:0055057 10 0.041
negative regulation of sister chromatid segregation GO:0033046 7 0.041
stem cell division GO:0017145 30 0.040
regulation of mapk cascade GO:0043408 248 0.040
dna integrity checkpoint GO:0031570 28 0.040
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.040
Yeast
positive regulation of organelle organization GO:0010638 128 0.040
Yeast
regulation of protein ubiquitination GO:0031396 52 0.040
regulation of hydrolase activity GO:0051336 246 0.040
leukocyte proliferation GO:0070661 172 0.040
response to alcohol GO:0097305 48 0.039
Rat
amine metabolic process GO:0009308 45 0.039
protein import into nucleus GO:0006606 95 0.039
cell fate specification GO:0001708 72 0.038
regulation of mitotic sister chromatid separation GO:0010965 12 0.038
ribonucleotide metabolic process GO:0009259 291 0.038
oxidation reduction process GO:0055114 342 0.038
protein import into nucleus translocation GO:0000060 12 0.038
hematopoietic progenitor cell differentiation GO:0002244 143 0.038
mitotic g2 dna damage checkpoint GO:0007095 8 0.038
Mouse
purine nucleoside catabolic process GO:0006152 205 0.038
negative regulation of gene silencing GO:0060969 2 0.038
camera type eye development GO:0043010 266 0.038
Rat
dna catabolic process GO:0006308 19 0.037
Yeast
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
dna conformation change GO:0071103 37 0.037
glycosyl compound metabolic process GO:1901657 246 0.037
response to oxygen levels GO:0070482 62 0.036
positive regulation of proteolysis GO:0045862 85 0.036
lymphocyte differentiation GO:0030098 242 0.036
positive regulation of chromosome segregation GO:0051984 4 0.036
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.036
negative regulation of gene expression epigenetic GO:0045814 15 0.036
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.036
mitotic cytokinesis GO:0000281 4 0.035
purine containing compound catabolic process GO:0072523 213 0.035
female gamete generation GO:0007292 74 0.035
nuclear import GO:0051170 95 0.035
chromatin assembly GO:0031497 13 0.035
response to inorganic substance GO:0010035 96 0.035
Rat
cellular response to oxidative stress GO:0034599 76 0.035
g2 m transition of mitotic cell cycle GO:0000086 20 0.035
negative regulation of mitotic sister chromatid separation GO:2000816 7 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.034
positive regulation of peptidase activity GO:0010952 49 0.034
tube formation GO:0035148 140 0.034
response to iron ion GO:0010039 4 0.034
spindle assembly involved in mitosis GO:0090307 4 0.034
neuroblast proliferation GO:0007405 49 0.034
actin cytoskeleton organization GO:0030036 220 0.034
response to nutrient GO:0007584 12 0.034
intracellular protein transport GO:0006886 204 0.034
response to oxidative stress GO:0006979 123 0.034
chemotaxis GO:0006935 247 0.033
regulation of cellular component biogenesis GO:0044087 181 0.033
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
dendrite development GO:0016358 115 0.032
muscle tissue development GO:0060537 308 0.032
b cell activation GO:0042113 161 0.032
mrna metabolic process GO:0016071 84 0.032
Yeast
regulation of intracellular protein transport GO:0033157 82 0.031
negative regulation of protein processing GO:0010955 79 0.031
cellular protein complex assembly GO:0043623 116 0.031
t cell activation GO:0042110 289 0.031
response to light stimulus GO:0009416 135 0.031
regulation of dna recombination GO:0000018 34 0.031
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
dephosphorylation GO:0016311 129 0.031
positive regulation of apoptotic signaling pathway GO:2001235 95 0.030
organonitrogen compound catabolic process GO:1901565 264 0.030
positive regulation of cell division GO:0051781 31 0.030
regulation of wnt signaling pathway GO:0030111 123 0.030
regulation of reactive oxygen species metabolic process GO:2000377 40 0.030
protein import GO:0017038 101 0.029
dna catabolic process exonucleolytic GO:0000738 3 0.029
Yeast
negative regulation of apoptotic signaling pathway GO:2001234 104 0.029
myeloid cell differentiation GO:0030099 233 0.029
neuronal stem cell division GO:0036445 10 0.029
regulation of cell cycle g2 m phase transition GO:1902749 10 0.029
lymphocyte proliferation GO:0046651 164 0.029
regulation of embryonic development GO:0045995 71 0.029
single organism nuclear import GO:1902593 95 0.029
endomembrane system organization GO:0010256 147 0.029
regulation of secretion by cell GO:1903530 249 0.029
inflammatory response GO:0006954 244 0.028
regulation of protein import into nucleus GO:0042306 52 0.028
regulation of intracellular transport GO:0032386 159 0.028
epithelial cell proliferation GO:0050673 174 0.028
ribonucleoside catabolic process GO:0042454 206 0.028
dna packaging GO:0006323 30 0.027
reciprocal dna recombination GO:0035825 16 0.027
negative regulation of protein catabolic process GO:0042177 36 0.027
purine containing compound metabolic process GO:0072521 311 0.027
protein complex disassembly GO:0043241 40 0.026
mrna processing GO:0006397 63 0.026
Yeast
regulation of membrane potential GO:0042391 192 0.026
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.026
endocytosis GO:0006897 168 0.025
purine nucleotide catabolic process GO:0006195 211 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
response to ionizing radiation GO:0010212 42 0.025
organophosphate biosynthetic process GO:0090407 122 0.025
regulation of epithelial cell proliferation GO:0050678 141 0.024
positive regulation of mapk cascade GO:0043410 170 0.024
positive regulation of fibroblast proliferation GO:0048146 20 0.024
locomotory behavior GO:0007626 195 0.024
er nucleus signaling pathway GO:0006984 27 0.024
nucleoside catabolic process GO:0009164 206 0.024
regulation of secretion GO:0051046 274 0.024
asymmetric cell division GO:0008356 8 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.024
positive regulation of transferase activity GO:0051347 167 0.023
fibroblast proliferation GO:0048144 35 0.023
cellular response to gamma radiation GO:0071480 4 0.023
glial cell apoptotic process GO:0034349 3 0.023
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.023
regulation of fibroblast proliferation GO:0048145 34 0.023
reactive oxygen species metabolic process GO:0072593 84 0.023
axonogenesis GO:0007409 274 0.023
regulation of cell activation GO:0050865 289 0.023
organelle localization GO:0051640 179 0.023
chromatin assembly or disassembly GO:0006333 16 0.023
regulation of endopeptidase activity GO:0052548 89 0.023
organophosphate catabolic process GO:0046434 232 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.022
regulation of protein targeting GO:1903533 61 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
lateral inhibition GO:0046331 1 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
response to peptide GO:1901652 136 0.022
Rat
response to topologically incorrect protein GO:0035966 25 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
Rat
purine ribonucleoside metabolic process GO:0046128 241 0.022
peptidyl amino acid modification GO:0018193 336 0.022
Yeast
respiratory system development GO:0060541 190 0.021
nitrogen compound transport GO:0071705 271 0.021
apoptotic mitochondrial changes GO:0008637 48 0.021
negative regulation of chromosome segregation GO:0051985 9 0.021
Yeast
regulation of protein localization to nucleus GO:1900180 60 0.021
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 6 0.021
epithelial tube morphogenesis GO:0060562 303 0.021
cell growth GO:0016049 130 0.021
gtp catabolic process GO:0006184 143 0.021
response to unfolded protein GO:0006986 21 0.021
regulation of protein complex assembly GO:0043254 83 0.021
oogenesis GO:0048477 56 0.021
ion transmembrane transport GO:0034220 361 0.021
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 8 0.020
striated muscle tissue development GO:0014706 293 0.020
morphogenesis of embryonic epithelium GO:0016331 159 0.020
regulation of response to dna damage stimulus GO:2001020 34 0.020
Yeast
regulation of establishment of protein localization GO:0070201 181 0.020
notch signaling pathway GO:0007219 71 0.020
peptidyl threonine modification GO:0018210 31 0.020
oocyte differentiation GO:0009994 35 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
male sex differentiation GO:0046661 109 0.020
meiosis i GO:0007127 60 0.020
Yeast
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 9 0.020
blood vessel morphogenesis GO:0048514 285 0.020
neuron projection guidance GO:0097485 141 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
cellular response to peptide hormone stimulus GO:0071375 92 0.020
Rat
negative regulation of dna replication GO:0008156 4 0.020
neural tube closure GO:0001843 90 0.020
regulation of cell shape GO:0008360 39 0.020
generation of precursor metabolites and energy GO:0006091 103 0.020
sister chromatid cohesion GO:0007062 12 0.019
Yeast
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.019
cellular chemical homeostasis GO:0055082 215 0.019
microtubule polymerization or depolymerization GO:0031109 26 0.019
regulation of lymphocyte apoptotic process GO:0070228 41 0.019
monocarboxylic acid metabolic process GO:0032787 191 0.019
release of cytochrome c from mitochondria GO:0001836 23 0.019
regulation of neuron projection development GO:0010975 169 0.019
protein depolymerization GO:0051261 34 0.019
establishment of protein localization to organelle GO:0072594 118 0.019
organ growth GO:0035265 117 0.019
negative regulation of kinase activity GO:0033673 81 0.019
response to lipopolysaccharide GO:0032496 128 0.019
neuron apoptotic process GO:0051402 142 0.019
negative regulation of protein phosphorylation GO:0001933 126 0.018
positive regulation of epithelial cell proliferation GO:0050679 68 0.018
neutral lipid metabolic process GO:0006638 57 0.018
Yeast
negative regulation of cell cycle g1 s phase transition GO:1902807 18 0.018
endoplasmic reticulum unfolded protein response GO:0030968 19 0.018
urogenital system development GO:0001655 261 0.018
somatic stem cell division GO:0048103 19 0.018
positive regulation of endopeptidase activity GO:0010950 43 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
embryonic epithelial tube formation GO:0001838 130 0.018
oocyte construction GO:0007308 2 0.018
regulation of ras protein signal transduction GO:0046578 114 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
regulation of chromatin binding GO:0035561 7 0.018
multi multicellular organism process GO:0044706 109 0.018
t cell differentiation in thymus GO:0033077 77 0.018
cell recognition GO:0008037 83 0.018
carbohydrate metabolic process GO:0005975 230 0.017
positive regulation of cell development GO:0010720 237 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
homeostasis of number of cells GO:0048872 210 0.017

Cdk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
immune system cancer DOID:0060083 0 0.018
hematologic cancer DOID:2531 0 0.018
organ system cancer DOID:0050686 0 0.018