Mus musculus

375 known processes

Cdk5

cyclin-dependent kinase 5

(Aliases: Crk6,AW048668)

Cdk5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
serine phosphorylation of stat protein GO:0042501 3 0.388
vesicle localization GO:0051648 86 0.219
Rat
microtubule based process GO:0007017 236 0.169
establishment of vesicle localization GO:0051650 81 0.159
Rat
positive regulation of intracellular transport GO:0032388 70 0.156
synaptic vesicle localization GO:0097479 59 0.132
Rat
cilium morphogenesis GO:0060271 102 0.121
camera type eye development GO:0043010 266 0.113
Zebrafish
establishment of organelle localization GO:0051656 122 0.112
Rat
regulation of cellular amino acid metabolic process GO:0006521 5 0.099
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.092
Fly
synaptic transmission GO:0007268 329 0.089
protein localization to membrane GO:0072657 108 0.076
membrane organization GO:0061024 245 0.076
microtubule cytoskeleton organization GO:0000226 157 0.074
organonitrogen compound catabolic process GO:1901565 264 0.070
establishment of protein localization to membrane GO:0090150 54 0.069
transmembrane transport GO:0055085 412 0.063
intracellular protein transport GO:0006886 204 0.062
amine metabolic process GO:0009308 45 0.062
regulation of establishment of protein localization GO:0070201 181 0.061
positive regulation of protein targeting to membrane GO:0090314 7 0.059
positive regulation of protein phosphorylation GO:0001934 242 0.059
apoptotic signaling pathway GO:0097190 306 0.058
Fly
regulation of transferase activity GO:0051338 263 0.057
regulation of protein transport GO:0051223 163 0.055
cilium assembly GO:0042384 81 0.053
protein targeting to membrane GO:0006612 20 0.053
organelle assembly GO:0070925 177 0.053
regulation of cell projection organization GO:0031344 206 0.052
cellular amine metabolic process GO:0044106 44 0.052
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.050
nucleobase containing small molecule metabolic process GO:0055086 352 0.049
purine nucleoside triphosphate catabolic process GO:0009146 203 0.049
regulation of neuron differentiation GO:0045664 281 0.048
cellular amino acid metabolic process GO:0006520 103 0.047
ribonucleotide metabolic process GO:0009259 291 0.045
positive regulation of programmed cell death GO:0043068 218 0.044
Rat
response to endoplasmic reticulum stress GO:0034976 53 0.044
Fly
regulation of microtubule based process GO:0032886 52 0.044
organophosphate catabolic process GO:0046434 232 0.043
ion transmembrane transport GO:0034220 361 0.041
nucleotide catabolic process GO:0009166 217 0.041
peptidyl threonine phosphorylation GO:0018107 31 0.040
organic cyclic compound catabolic process GO:1901361 295 0.039
positive regulation of kinase activity GO:0033674 155 0.039
adult behavior GO:0030534 135 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.037
organelle localization GO:0051640 179 0.037
Rat Fly
positive regulation of apoptotic process GO:0043065 217 0.036
Rat
nucleoside metabolic process GO:0009116 246 0.036
nucleoside catabolic process GO:0009164 206 0.035
cytoplasmic transport GO:0016482 234 0.034
purine nucleotide metabolic process GO:0006163 302 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.033
regulation of protein localization GO:0032880 231 0.033
cellular macromolecule catabolic process GO:0044265 206 0.033
cellular nitrogen compound catabolic process GO:0044270 280 0.032
aromatic compound catabolic process GO:0019439 286 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
negative regulation of cell development GO:0010721 169 0.031
regulation of organelle organization GO:0033043 289 0.031
purine containing compound metabolic process GO:0072521 311 0.031
regulation of kinase activity GO:0043549 249 0.031
nitrogen compound transport GO:0071705 271 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
ribonucleoside metabolic process GO:0009119 245 0.030
intrinsic apoptotic signaling pathway GO:0097193 132 0.030
Fly
negative regulation of cellular component organization GO:0051129 194 0.030
regulation of microtubule cytoskeleton organization GO:0070507 37 0.029
positive regulation of protein modification process GO:0031401 299 0.029
negative regulation of cell projection organization GO:0031345 56 0.028
organelle fission GO:0048285 170 0.028
nucleotide metabolic process GO:0009117 332 0.027
negative regulation of growth GO:0045926 99 0.027
immune effector process GO:0002252 321 0.027
Fly
ribonucleoside catabolic process GO:0042454 206 0.027
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.026
heterocycle catabolic process GO:0046700 280 0.026
peptidyl amino acid modification GO:0018193 336 0.026
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
cellular lipid metabolic process GO:0044255 323 0.026
protein targeting GO:0006605 143 0.026
ribonucleotide catabolic process GO:0009261 208 0.026
protein ubiquitination GO:0016567 171 0.026
regulation of protein kinase activity GO:0045859 232 0.026
regulation of protein targeting to membrane GO:0090313 9 0.026
positive regulation of intracellular protein transport GO:0090316 42 0.026
regulation of neuron projection development GO:0010975 169 0.026
positive regulation of secretion GO:0051047 130 0.025
lateral inhibition GO:0046331 1 0.025
carbohydrate derivative catabolic process GO:1901136 231 0.025
ubiquitin dependent protein catabolic process GO:0006511 129 0.025
regulation of proteolysis GO:0030162 164 0.025
Human
regulation of gtp catabolic process GO:0033124 113 0.025
modification dependent macromolecule catabolic process GO:0043632 133 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
regulation of vesicle mediated transport GO:0060627 139 0.024
acetylcholine transport GO:0015870 2 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
cation transport GO:0006812 399 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
organic hydroxy compound metabolic process GO:1901615 203 0.024
Fly
regulation of cellular component biogenesis GO:0044087 181 0.023
Fly
purine nucleoside metabolic process GO:0042278 241 0.023
response to inorganic substance GO:0010035 96 0.023
macromolecule catabolic process GO:0009057 281 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
purine containing compound catabolic process GO:0072523 213 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.023
regulation of cytoskeleton organization GO:0051493 122 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.022
establishment of synaptic vesicle localization GO:0097480 57 0.022
Rat
regulation of cell size GO:0008361 72 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
neural tube development GO:0021915 160 0.022
inorganic cation transmembrane transport GO:0098662 207 0.022
protein modification by small protein conjugation GO:0032446 187 0.021
dna metabolic process GO:0006259 303 0.021
positive regulation of tor signaling GO:0032008 3 0.021
sensory system development GO:0048880 3 0.021
neuron neuron synaptic transmission GO:0007270 69 0.020
regulation of exocytosis GO:0017157 61 0.020
response to radiation GO:0009314 165 0.020
cellular component assembly involved in morphogenesis GO:0010927 139 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
positive regulation of cell death GO:0010942 224 0.019
Rat
guanosine containing compound metabolic process GO:1901068 144 0.019
regulation of cell growth GO:0001558 91 0.019
negative regulation of neuron differentiation GO:0045665 101 0.019
positive regulation of transferase activity GO:0051347 167 0.019
negative regulation of nervous system development GO:0051961 156 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
skeletal system development GO:0001501 356 0.019
gtp metabolic process GO:0046039 144 0.019
endomembrane system organization GO:0010256 147 0.019
cellular protein catabolic process GO:0044257 155 0.018
establishment of melanosome localization GO:0032401 11 0.018
regulation of anatomical structure size GO:0090066 178 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
glycerolipid metabolic process GO:0046486 122 0.018
actin cytoskeleton organization GO:0030036 220 0.018
Rat
nucleoside triphosphate catabolic process GO:0009143 205 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
retina development in camera type eye GO:0060041 119 0.018
Zebrafish
peptidyl tyrosine modification GO:0018212 145 0.018
glial cell differentiation GO:0010001 131 0.017
cellular ketone metabolic process GO:0042180 84 0.017
ephrin receptor signaling pathway GO:0048013 20 0.017
regionalization GO:0003002 337 0.017
golgi to endosome transport GO:0006895 3 0.017
developmental maturation GO:0021700 193 0.017
regulation of cell cycle GO:0051726 281 0.017
nuclear division GO:0000280 158 0.017
purine nucleotide catabolic process GO:0006195 211 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
rho protein signal transduction GO:0007266 32 0.016
cation transmembrane transport GO:0098655 266 0.016
smoothened signaling pathway GO:0007224 105 0.016
skin development GO:0043588 220 0.016
regulation of protein complex assembly GO:0043254 83 0.016
divalent inorganic cation transport GO:0072511 178 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
positive regulation of organelle organization GO:0010638 128 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
peptide secretion GO:0002790 114 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.015
regulation of hydrolase activity GO:0051336 246 0.015
kidney development GO:0001822 213 0.015
acetate ester transport GO:1901374 2 0.015
response to organic cyclic compound GO:0014070 198 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
spermatogenesis GO:0007283 284 0.015
multicellular organism growth GO:0035264 161 0.015
positive regulation of cell projection organization GO:0031346 95 0.015
anatomical structure maturation GO:0071695 49 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
negative regulation of synapse assembly GO:0051964 3 0.015
regulation of cellular response to stress GO:0080135 159 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
peptidyl tyrosine phosphorylation GO:0018108 143 0.015
transmission of nerve impulse GO:0019226 76 0.015
regulation of secretion GO:0051046 274 0.015
cellular chemical homeostasis GO:0055082 215 0.015
renal system development GO:0072001 225 0.014
positive regulation of nervous system development GO:0051962 221 0.014
compound eye development GO:0048749 1 0.014
sequestering of calcium ion GO:0051208 18 0.014
locomotory behavior GO:0007626 195 0.014
Fly
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
regulation of binding GO:0051098 111 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
cell cycle arrest GO:0007050 37 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
mapk cascade GO:0000165 281 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
phenol containing compound metabolic process GO:0018958 60 0.014
Fly
reactive oxygen species metabolic process GO:0072593 84 0.014
pigment metabolic process GO:0042440 32 0.014
Fly
regulation of cell motility GO:2000145 236 0.014
glycerophospholipid metabolic process GO:0006650 71 0.014
fat cell differentiation GO:0045444 160 0.014
cellular response to biotic stimulus GO:0071216 92 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
positive regulation of protein transport GO:0051222 93 0.013
pigmentation GO:0043473 71 0.013
carbohydrate homeostasis GO:0033500 128 0.013
neural retina development GO:0003407 41 0.013
Zebrafish
glycoprotein metabolic process GO:0009100 116 0.013
regulation of ion transport GO:0043269 215 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
response to metal ion GO:0010038 47 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
regulation of cell cycle process GO:0010564 160 0.013
calcium ion homeostasis GO:0055074 127 0.013
positive regulation of cell cycle process GO:0090068 61 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
peptidyl glutamic acid modification GO:0018200 13 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
lateral line system development GO:0048925 1 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
regulation of tor signaling GO:0032006 17 0.013
divalent metal ion transport GO:0070838 172 0.013
hydrogen ion transmembrane transport GO:1902600 25 0.013
regulation of neurotransmitter levels GO:0001505 87 0.013
regulation of actin filament based process GO:0032970 99 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
metal ion homeostasis GO:0055065 189 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
endocytosis GO:0006897 168 0.013
Rat
positive regulation of cell development GO:0010720 237 0.012
response to growth factor GO:0070848 198 0.012
cell adhesion GO:0007155 329 0.012
phospholipid metabolic process GO:0006644 87 0.012
innate immune response GO:0045087 157 0.012
Fly
positive regulation of ion transport GO:0043270 65 0.012
peptide hormone secretion GO:0030072 109 0.012
protein import GO:0017038 101 0.012
cell growth GO:0016049 130 0.012
cellular homeostasis GO:0019725 240 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
hormone secretion GO:0046879 128 0.012
negative regulation of molecular function GO:0044092 258 0.012
layer formation in cerebral cortex GO:0021819 13 0.012
attachment of spindle microtubules to kinetochore GO:0008608 4 0.012
synaptic vesicle transport GO:0048489 57 0.012
Rat
modification dependent protein catabolic process GO:0019941 133 0.012
axoneme assembly GO:0035082 15 0.012
jak stat cascade GO:0007259 42 0.012
protein catabolic process GO:0030163 221 0.012
retina morphogenesis in camera type eye GO:0060042 45 0.012
Zebrafish
macroautophagy GO:0016236 21 0.012
response to organonitrogen compound GO:0010243 246 0.012
ceramide biosynthetic process GO:0046513 20 0.012
ras protein signal transduction GO:0007265 77 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
extracellular structure organization GO:0043062 148 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
nuclear transport GO:0051169 139 0.011
lipid biosynthetic process GO:0008610 179 0.011
nuclear import GO:0051170 95 0.011
gland development GO:0048732 330 0.011
neuron projection guidance GO:0097485 141 0.011
gtp catabolic process GO:0006184 143 0.011
calcium ion transport GO:0006816 159 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
regulation of endocytosis GO:0030100 69 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
sensory organ morphogenesis GO:0090596 242 0.011
Zebrafish
cell division GO:0051301 120 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
urogenital system development GO:0001655 261 0.011
sequestering of metal ion GO:0051238 19 0.011
forebrain cell migration GO:0021885 58 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
regulation of mapk cascade GO:0043408 248 0.011
carbohydrate metabolic process GO:0005975 230 0.011
axonogenesis GO:0007409 274 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
synapse assembly GO:0007416 56 0.011
positive regulation of neuron projection development GO:0010976 79 0.011
regulation of intracellular transport GO:0032386 159 0.011
hindbrain maturation GO:0021578 6 0.011
negative regulation of cell growth GO:0030308 44 0.011
positive regulation of cell activation GO:0050867 158 0.011
male gamete generation GO:0048232 285 0.011
regulation of homeostatic process GO:0032844 182 0.010
cation homeostasis GO:0055080 212 0.010
tube formation GO:0035148 140 0.010
cellular ion homeostasis GO:0006873 165 0.010
cellular response to extracellular stimulus GO:0031668 81 0.010
maintenance of location GO:0051235 89 0.010
negative regulation of neuron projection development GO:0010977 50 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.010
asymmetric stem cell division GO:0098722 3 0.010
positive regulation of homeostatic process GO:0032846 64 0.010
epidermis development GO:0008544 187 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
regulation of peptide hormone secretion GO:0090276 75 0.010
proton transport GO:0015992 35 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
regulation of transmembrane transport GO:0034762 128 0.010

Cdk5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011