Mus musculus

0 known processes

Cdk8

cyclin-dependent kinase 8

(Aliases: MGC37111)

Cdk8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.138
axonogenesis GO:0007409 274 0.112
Fly
ras protein signal transduction GO:0007265 77 0.109
small gtpase mediated signal transduction GO:0007264 97 0.096
amine metabolic process GO:0009308 45 0.096
dna repair GO:0006281 107 0.094
cellular response to dna damage stimulus GO:0006974 207 0.086
Fly
dna metabolic process GO:0006259 303 0.085
cellular homeostasis GO:0019725 240 0.084
regulation of cellular component size GO:0032535 121 0.078
regulation of ras gtpase activity GO:0032318 88 0.074
asymmetric neuroblast division GO:0055059 1 0.069
positive regulation of cellular catabolic process GO:0031331 148 0.067
posttranscriptional regulation of gene expression GO:0010608 155 0.064
Yeast
regulation of translation GO:0006417 71 0.062
cellular amino acid metabolic process GO:0006520 103 0.060
cellular amine metabolic process GO:0044106 44 0.059
cation transport GO:0006812 399 0.057
purine ribonucleotide metabolic process GO:0009150 290 0.055
carbohydrate derivative biosynthetic process GO:1901137 183 0.054
regulation of cellular amine metabolic process GO:0033238 20 0.054
mitotic cell cycle process GO:1903047 159 0.052
Fly
heterocycle catabolic process GO:0046700 280 0.051
Yeast
regulation of anatomical structure size GO:0090066 178 0.051
nucleobase containing small molecule metabolic process GO:0055086 352 0.051
regulation of organelle organization GO:0033043 289 0.050
ribose phosphate metabolic process GO:0019693 291 0.050
nucleotide metabolic process GO:0009117 332 0.050
regulation of cytokine production GO:0001817 266 0.050
ribonucleotide metabolic process GO:0009259 291 0.046
negative regulation of protein metabolic process GO:0051248 282 0.045
compound eye development GO:0048749 1 0.045
divalent inorganic cation transport GO:0072511 178 0.044
translation GO:0006412 93 0.043
positive regulation of organelle organization GO:0010638 128 0.043
regulation of hydrolase activity GO:0051336 246 0.043
nucleoside phosphate metabolic process GO:0006753 338 0.042
negative regulation of dna replication GO:0008156 4 0.041
wound healing GO:0042060 157 0.041
rho protein signal transduction GO:0007266 32 0.040
regulation of cell cycle GO:0051726 281 0.039
Yeast Fly
nucleoside metabolic process GO:0009116 246 0.039
regulation of cellular catabolic process GO:0031329 242 0.039
ion transmembrane transport GO:0034220 361 0.039
organonitrogen compound biosynthetic process GO:1901566 192 0.038
carbohydrate derivative catabolic process GO:1901136 231 0.037
asymmetric stem cell division GO:0098722 3 0.037
cation transmembrane transport GO:0098655 266 0.037
macromolecule catabolic process GO:0009057 281 0.035
Yeast
cellular nitrogen compound catabolic process GO:0044270 280 0.035
Yeast
metal ion homeostasis GO:0055065 189 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.035
positive regulation of nucleoside metabolic process GO:0045979 91 0.034
ribonucleotide catabolic process GO:0009261 208 0.033
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.033
organophosphate biosynthetic process GO:0090407 122 0.033
glycosyl compound metabolic process GO:1901657 246 0.033
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.031
peptidyl amino acid modification GO:0018193 336 0.030
negative regulation of cellular protein metabolic process GO:0032269 247 0.030
positive regulation of nucleotide metabolic process GO:0045981 114 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
regulation of nucleotide catabolic process GO:0030811 122 0.029
cytokine production GO:0001816 319 0.029
positive regulation of innate immune response GO:0045089 80 0.029
cation homeostasis GO:0055080 212 0.029
cellular ion homeostasis GO:0006873 165 0.028
inorganic cation transmembrane transport GO:0098662 207 0.028
cell adhesion GO:0007155 329 0.028
endocytosis GO:0006897 168 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
Yeast
microtubule based process GO:0007017 236 0.028
gland development GO:0048732 330 0.027
cellular response to growth factor stimulus GO:0071363 197 0.027
positive regulation of growth GO:0045927 104 0.027
aromatic compound catabolic process GO:0019439 286 0.027
Yeast
regulation of nucleotide metabolic process GO:0006140 169 0.027
regulation of nucleoside metabolic process GO:0009118 130 0.027
cell type specific apoptotic process GO:0097285 268 0.026
regulation of actin nucleation GO:0051125 4 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
response to light stimulus GO:0009416 135 0.026
negative regulation of apoptotic signaling pathway GO:2001234 104 0.025
nucleoside phosphate catabolic process GO:1901292 222 0.025
protein acylation GO:0043543 64 0.025
locomotory behavior GO:0007626 195 0.025
multicellular organism growth GO:0035264 161 0.024
developmental cell growth GO:0048588 84 0.024
cellular metal ion homeostasis GO:0006875 151 0.024
angiogenesis GO:0001525 201 0.024
cellular ketone metabolic process GO:0042180 84 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.024
negative regulation of protein modification process GO:0031400 163 0.024
defense response to other organism GO:0098542 197 0.024
mitotic cell cycle GO:0000278 195 0.023
Fly
ribonucleoside metabolic process GO:0009119 245 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.022
actin cytoskeleton organization GO:0030036 220 0.022
g protein coupled receptor signaling pathway GO:0007186 243 0.022
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.022
regulation of neuron differentiation GO:0045664 281 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
positive regulation of hydrolase activity GO:0051345 148 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
positive regulation of gtpase activity GO:0043547 85 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
nitrogen compound transport GO:0071705 271 0.021
forebrain development GO:0030900 302 0.021
apoptotic signaling pathway GO:0097190 306 0.020
regulation of innate immune response GO:0045088 91 0.020
regulation of purine nucleotide catabolic process GO:0033121 122 0.020
regulation of histone modification GO:0031056 56 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
response to oxidative stress GO:0006979 123 0.020
positive regulation of nucleotide catabolic process GO:0030813 88 0.020
macromolecule methylation GO:0043414 120 0.019
regulation of gtp catabolic process GO:0033124 113 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
cellular chemical homeostasis GO:0055082 215 0.019
membrane organization GO:0061024 245 0.019
regulation of body fluid levels GO:0050878 162 0.019
developmental growth involved in morphogenesis GO:0060560 138 0.019
nucleus organization GO:0006997 45 0.018
peptidyl serine phosphorylation GO:0018105 74 0.018
central nervous system neuron differentiation GO:0021953 162 0.018
osteoclast differentiation GO:0030316 62 0.018
innate immune response GO:0045087 157 0.018
cofactor biosynthetic process GO:0051188 41 0.018
myeloid leukocyte differentiation GO:0002573 119 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
proteasomal protein catabolic process GO:0010498 98 0.018
ribonucleoside catabolic process GO:0042454 206 0.017
regulation of membrane potential GO:0042391 192 0.017
skeletal system development GO:0001501 356 0.017
cellular protein complex assembly GO:0043623 116 0.017
nucleoside catabolic process GO:0009164 206 0.017
cell division GO:0051301 120 0.017
homeostasis of number of cells GO:0048872 210 0.017
neuron projection extension GO:1990138 64 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.017
regulation of cell projection organization GO:0031344 206 0.017
cellular amide metabolic process GO:0043603 58 0.016
regulation of cellular response to growth factor stimulus GO:0090287 82 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
Fly
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
glycoprotein metabolic process GO:0009100 116 0.016
negative regulation of synapse assembly GO:0051964 3 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
neural precursor cell proliferation GO:0061351 121 0.016
cell growth GO:0016049 130 0.016
n terminal protein amino acid modification GO:0031365 6 0.016
cell proliferation involved in heart valve development GO:2000793 2 0.016
regulation of chromatin modification GO:1903308 57 0.016
epithelial cell proliferation GO:0050673 174 0.016
positive regulation of ras gtpase activity GO:0032320 65 0.016
neuronal action potential GO:0019228 54 0.016
digestive system development GO:0055123 200 0.015
guanosine containing compound catabolic process GO:1901069 144 0.015
cell maturation GO:0048469 127 0.015
lipid localization GO:0010876 126 0.015
maternal determination of anterior posterior axis embryo GO:0008358 2 0.015
protein localization to membrane GO:0072657 108 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
positive regulation of gene silencing by mirna GO:2000637 1 0.015
stem cell division GO:0017145 30 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
regulation of mitotic cell cycle phase transition GO:1901990 73 0.015
Fly
myeloid cell differentiation GO:0030099 233 0.015
regulation of protein localization GO:0032880 231 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
fat cell differentiation GO:0045444 160 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
actin filament organization GO:0007015 113 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
action potential GO:0001508 78 0.014
peptidyl serine modification GO:0018209 83 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
regulation of cell motility GO:2000145 236 0.014
negative regulation of molecular function GO:0044092 258 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
carbohydrate metabolic process GO:0005975 230 0.014
placenta development GO:0001890 140 0.014
feeding behavior GO:0007631 62 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
calcium ion transport GO:0006816 159 0.013
spermatogenesis GO:0007283 284 0.013
nucleotide catabolic process GO:0009166 217 0.013
organophosphate catabolic process GO:0046434 232 0.013
leukocyte differentiation GO:0002521 342 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
neuron apoptotic process GO:0051402 142 0.013
regulation of defense response GO:0031347 233 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
gastrulation GO:0007369 116 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
regulation of kinase activity GO:0043549 249 0.012
stem cell differentiation GO:0048863 268 0.012
positive regulation of cell development GO:0010720 237 0.012
sulfur compound biosynthetic process GO:0044272 37 0.012
regulation of proteolysis GO:0030162 164 0.012
sulfur compound metabolic process GO:0006790 100 0.012
cell fate commitment GO:0045165 210 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
response to transforming growth factor beta GO:0071559 88 0.012
ribonucleotide biosynthetic process GO:0009260 59 0.012
regulation of cytokine biosynthetic process GO:0042035 59 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
ribosomal small subunit biogenesis GO:0042274 4 0.012
lipid biosynthetic process GO:0008610 179 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.012
cellular protein catabolic process GO:0044257 155 0.012
epidermis development GO:0008544 187 0.012
regulation of interferon beta production GO:0032648 13 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
negative regulation of cell development GO:0010721 169 0.012
male gamete generation GO:0048232 285 0.011
response to growth factor GO:0070848 198 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
digestive tract development GO:0048565 190 0.011
regulation of transmembrane transport GO:0034762 128 0.011
multicellular organismal signaling GO:0035637 91 0.011
stem cell proliferation GO:0072089 117 0.011
synapse organization GO:0050808 125 0.011
positive regulation of kinase activity GO:0033674 155 0.011
synaptic transmission GO:0007268 329 0.011
skin development GO:0043588 220 0.011
negative regulation of cytokine production GO:0001818 84 0.011
regulation of ossification GO:0030278 112 0.011
chemotaxis GO:0006935 247 0.011
Fly
blood vessel morphogenesis GO:0048514 285 0.011
regulation of antimicrobial humoral response GO:0002759 3 0.011
lung morphogenesis GO:0060425 50 0.011
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
antimicrobial peptide biosynthetic process GO:0002777 2 0.011
regulation of cell size GO:0008361 72 0.011
cytokine metabolic process GO:0042107 71 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
response to organonitrogen compound GO:0010243 246 0.011
divalent metal ion transport GO:0070838 172 0.011
defense response to bacterium GO:0042742 119 0.011
regulation of actin filament based process GO:0032970 99 0.011
cytoplasmic transport GO:0016482 234 0.011
urogenital system development GO:0001655 261 0.011
regionalization GO:0003002 337 0.010
Fly
positive regulation of gtp catabolic process GO:0033126 85 0.010
regulation of ion transport GO:0043269 215 0.010
regulation of chromosome organization GO:0033044 83 0.010
positive regulation of defense response GO:0031349 124 0.010
anatomical structure homeostasis GO:0060249 145 0.010
regulation of extent of cell growth GO:0061387 52 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
gtp catabolic process GO:0006184 143 0.010
purine containing compound metabolic process GO:0072521 311 0.010
cellular macromolecule catabolic process GO:0044265 206 0.010
Yeast
adult locomotory behavior GO:0008344 91 0.010
response to temperature stimulus GO:0009266 55 0.010
regulation of cell activation GO:0050865 289 0.010
cellular transition metal ion homeostasis GO:0046916 32 0.010
maintenance of location GO:0051235 89 0.010
regulation of peptidyl lysine acetylation GO:2000756 22 0.010

Cdk8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
musculoskeletal system disease DOID:17 0 0.015