Mus musculus

13 known processes

Sprr2e

small proline-rich protein 2E

Sprr2e biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of ion transport GO:0043269 215 0.057
response to lipopolysaccharide GO:0032496 128 0.043
transmembrane transport GO:0055085 412 0.043
nucleotide metabolic process GO:0009117 332 0.042
cation transmembrane transport GO:0098655 266 0.040
regulation of blood pressure GO:0008217 93 0.039
cellular homeostasis GO:0019725 240 0.037
response to molecule of bacterial origin GO:0002237 143 0.037
cellular ion homeostasis GO:0006873 165 0.037
cellular chemical homeostasis GO:0055082 215 0.033
male gamete generation GO:0048232 285 0.032
regulation of system process GO:0044057 200 0.030
regulation of systemic arterial blood pressure GO:0003073 61 0.029
ion transmembrane transport GO:0034220 361 0.029
cellular amine metabolic process GO:0044106 44 0.029
aromatic compound catabolic process GO:0019439 286 0.029
metal ion homeostasis GO:0055065 189 0.029
cellular metal ion homeostasis GO:0006875 151 0.028
cation transport GO:0006812 399 0.028
cellular response to lipid GO:0071396 145 0.028
cellular response to lipopolysaccharide GO:0071222 77 0.027
inflammatory response GO:0006954 244 0.027
camera type eye development GO:0043010 266 0.027
divalent inorganic cation transport GO:0072511 178 0.027
regulation of defense response GO:0031347 233 0.027
regulation of inflammatory response GO:0050727 147 0.026
cellular calcium ion homeostasis GO:0006874 119 0.025
response to organic cyclic compound GO:0014070 198 0.025
regulation of secretion GO:0051046 274 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
response to organonitrogen compound GO:0010243 246 0.024
cytosolic calcium ion homeostasis GO:0051480 70 0.024
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.023
meiotic nuclear division GO:0007126 115 0.023
regulation of cell cycle GO:0051726 281 0.023
spermatogenesis GO:0007283 284 0.023
regulation of anatomical structure size GO:0090066 178 0.023
regulation of cell activation GO:0050865 289 0.022
cellular potassium ion transport GO:0071804 43 0.022
potassium ion transmembrane transport GO:0071805 43 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
regulation of membrane potential GO:0042391 192 0.022
interleukin 5 secretion GO:0072603 2 0.021
cellular response to molecule of bacterial origin GO:0071219 83 0.021
regulation of tube size GO:0035150 57 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
negative regulation of interleukin 13 production GO:0032696 2 0.021
negative regulation of cell proliferation GO:0008285 296 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
protein catabolic process GO:0030163 221 0.020
regulation of secretion by cell GO:1903530 249 0.020
blood vessel morphogenesis GO:0048514 285 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
regulation of neuron differentiation GO:0045664 281 0.020
organelle fission GO:0048285 170 0.019
nuclear division GO:0000280 158 0.019
cellular response to biotic stimulus GO:0071216 92 0.019
cell cell recognition GO:0009988 44 0.019
synaptic transmission GO:0007268 329 0.019
fertilization GO:0009566 127 0.019
purine containing compound metabolic process GO:0072521 311 0.019
t cell activation GO:0042110 289 0.019
ribonucleotide metabolic process GO:0009259 291 0.018
cellular amino acid metabolic process GO:0006520 103 0.018
calcium ion homeostasis GO:0055074 127 0.018
response to light stimulus GO:0009416 135 0.018
cell type specific apoptotic process GO:0097285 268 0.018
regulation of mapk cascade GO:0043408 248 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
negative regulation of immune system process GO:0002683 209 0.018
nitrogen compound transport GO:0071705 271 0.018
cation homeostasis GO:0055080 212 0.018
regulation of response to wounding GO:1903034 189 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
apoptotic signaling pathway GO:0097190 306 0.017
regulation of kinase activity GO:0043549 249 0.017
regulation of cytokine production GO:0001817 266 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
organelle localization GO:0051640 179 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
regulation of protein serine threonine kinase activity GO:0071900 157 0.017
regulation of stress activated mapk cascade GO:0032872 69 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
ribose phosphate metabolic process GO:0019693 291 0.016
regulation of interleukin 13 secretion GO:2000665 2 0.016
regulation of cell migration GO:0030334 219 0.016
oxidation reduction process GO:0055114 342 0.016
epithelial cell development GO:0002064 159 0.016
calcium ion transport GO:0006816 159 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.016
regulation of hormone levels GO:0010817 211 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
protein secretion GO:0009306 111 0.016
heterocycle catabolic process GO:0046700 280 0.016
germ cell development GO:0007281 185 0.015
organic hydroxy compound transport GO:0015850 93 0.015
negative regulation of cell size GO:0045792 3 0.015
regulation of protein localization GO:0032880 231 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
sperm egg recognition GO:0035036 37 0.015
mapk cascade GO:0000165 281 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
glycoprotein metabolic process GO:0009100 116 0.015
transmission of nerve impulse GO:0019226 76 0.015
lipid transport GO:0006869 98 0.015
conditioned taste aversion GO:0001661 4 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.015
positive regulation of protein modification process GO:0031401 299 0.015
cellular response to amino acid stimulus GO:0071230 29 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.014
gland development GO:0048732 330 0.014
multicellular organism growth GO:0035264 161 0.014
sequestering of metal ion GO:0051238 19 0.014
spermatid development GO:0007286 108 0.014
positive regulation of cell development GO:0010720 237 0.014
dna metabolic process GO:0006259 303 0.014
sensory perception GO:0007600 245 0.014
regulation of protein transport GO:0051223 163 0.014
hormone secretion GO:0046879 128 0.014
smooth muscle contraction GO:0006939 44 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
protein maturation GO:0051604 176 0.014
interleukin 13 secretion GO:0072611 2 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
regulation of cell motility GO:2000145 236 0.014
multicellular organismal signaling GO:0035637 91 0.014
regulation of adaptive immune response GO:0002819 90 0.014
regulation of organelle organization GO:0033043 289 0.014
translation GO:0006412 93 0.014
potassium ion transport GO:0006813 52 0.014
nucleotide biosynthetic process GO:0009165 78 0.014
organic anion transport GO:0015711 137 0.014
response to acid chemical GO:0001101 111 0.014
regulation of interleukin 5 secretion GO:2000662 2 0.014
adaptive immune response GO:0002250 155 0.014
tissue remodeling GO:0048771 102 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
regulation of proteolysis GO:0030162 164 0.013
ribose phosphate biosynthetic process GO:0046390 59 0.013
microtubule based process GO:0007017 236 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
stem cell differentiation GO:0048863 268 0.013
negative regulation of protein modification process GO:0031400 163 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
cell division GO:0051301 120 0.013
anion transport GO:0006820 177 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.013
membrane organization GO:0061024 245 0.013
negative regulation of interleukin 5 production GO:0032714 4 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
cell growth GO:0016049 130 0.013
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.013
negative regulation of interleukin 5 secretion GO:2000663 1 0.013
striated muscle tissue development GO:0014706 293 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
regulation of action potential GO:0098900 4 0.012
carbohydrate homeostasis GO:0033500 128 0.012
negative regulation of serotonin secretion GO:0014063 2 0.012
leukocyte migration GO:0050900 124 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
regulation of cellular amino acid metabolic process GO:0006521 5 0.012
response to peptide hormone GO:0043434 127 0.012
regulation of cellular amine metabolic process GO:0033238 20 0.012
lymphocyte proliferation GO:0046651 164 0.012
angiogenesis GO:0001525 201 0.012
regulation of transferase activity GO:0051338 263 0.012
regulation of map kinase activity GO:0043405 120 0.012
neuron apoptotic process GO:0051402 142 0.012
oocyte axis specification GO:0007309 2 0.012
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.012
organophosphate catabolic process GO:0046434 232 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
negative regulation of systemic arterial blood pressure GO:0003085 15 0.012
regulation of circadian sleep wake cycle GO:0042749 3 0.012
macromolecule catabolic process GO:0009057 281 0.012
regulation of cellular response to stress GO:0080135 159 0.012
neuron death GO:0070997 154 0.012
regulation of neuron death GO:1901214 134 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
glucose homeostasis GO:0042593 128 0.012
leukocyte proliferation GO:0070661 172 0.012
response to inorganic substance GO:0010035 96 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
action potential GO:0001508 78 0.012
cytoplasmic transport GO:0016482 234 0.011
mature dendritic cell differentiation GO:0097029 3 0.011
regulation of cellular component size GO:0032535 121 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
meiotic cell cycle GO:0051321 122 0.011
sulfur compound metabolic process GO:0006790 100 0.011
blood circulation GO:0008015 195 0.011
peptide secretion GO:0002790 114 0.011
vascular process in circulatory system GO:0003018 62 0.011
defense response to bacterium GO:0042742 119 0.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.011
maintenance of location GO:0051235 89 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
intracellular mrna localization GO:0008298 4 0.011
response to growth factor GO:0070848 198 0.011
negative regulation of interleukin 13 secretion GO:2000666 1 0.011
muscle cell differentiation GO:0042692 261 0.011
positive regulation of transferase activity GO:0051347 167 0.011
renal system process GO:0003014 48 0.011
positive regulation of kinase activity GO:0033674 155 0.011
nucleoside catabolic process GO:0009164 206 0.011
regulation of blood vessel size GO:0050880 56 0.011
immune effector process GO:0002252 321 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.011
negative regulation of blood pressure GO:0045776 22 0.011
fat cell differentiation GO:0045444 160 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
lateral inhibition GO:0046331 1 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
lipid biosynthetic process GO:0008610 179 0.011
digestive tract development GO:0048565 190 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress GO:1902219 1 0.010
response to amino acid GO:0043200 37 0.010
purine containing compound biosynthetic process GO:0072522 70 0.010
positive regulation of monocyte chemotaxis GO:0090026 2 0.010
forebrain development GO:0030900 302 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
regulation of jnk cascade GO:0046328 62 0.010
myotube differentiation GO:0014902 105 0.010
leukocyte mediated immunity GO:0002443 174 0.010
amide transport GO:0042886 138 0.010
glycosyl compound metabolic process GO:1901657 246 0.010
positive regulation of vasoconstriction GO:0045907 4 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
divalent metal ion transport GO:0070838 172 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
neuronal action potential GO:0019228 54 0.010
protein processing GO:0016485 163 0.010
regulation of t cell activation GO:0050863 170 0.010
regulation of serotonin secretion GO:0014062 3 0.010
memory GO:0007613 58 0.010

Sprr2e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.018
eye disease DOID:5614 0 0.018
disease of metabolism DOID:0014667 0 0.016
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
cancer DOID:162 0 0.015
retinal disease DOID:5679 0 0.014
neurodegenerative disease DOID:1289 0 0.013
central nervous system disease DOID:331 0 0.013