Mus musculus

33 known processes

Sprr2d

small proline-rich protein 2D

Sprr2d biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 243 0.300
t helper 2 cell cytokine production GO:0035745 4 0.272
cytokine mediated signaling pathway GO:0019221 115 0.157
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.106
regulation of hormone levels GO:0010817 211 0.105
regulation of cell migration GO:0030334 219 0.087
amide transport GO:0042886 138 0.085
regulation of cytokine production GO:0001817 266 0.085
leukocyte differentiation GO:0002521 342 0.084
apoptotic signaling pathway GO:0097190 306 0.083
cell type specific apoptotic process GO:0097285 268 0.081
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.080
cellular amine metabolic process GO:0044106 44 0.078
hematopoietic progenitor cell differentiation GO:0002244 143 0.068
lymphocyte activation involved in immune response GO:0002285 93 0.064
peptide transport GO:0015833 133 0.064
hepatocyte apoptotic process GO:0097284 11 0.063
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
striated muscle tissue development GO:0014706 293 0.057
amine metabolic process GO:0009308 45 0.056
inflammatory response GO:0006954 244 0.055
fat cell differentiation GO:0045444 160 0.055
gland development GO:0048732 330 0.055
nitrogen compound transport GO:0071705 271 0.054
regulation of cell motility GO:2000145 236 0.053
peptide secretion GO:0002790 114 0.050
cellular ketone metabolic process GO:0042180 84 0.049
negative regulation of muscle cell differentiation GO:0051148 33 0.048
regulation of establishment of protein localization GO:0070201 181 0.047
regulation of cellular ketone metabolic process GO:0010565 66 0.047
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.047
intermediate filament cytoskeleton organization GO:0045104 26 0.047
leukocyte activation involved in immune response GO:0002366 126 0.046
positive regulation of protein modification process GO:0031401 299 0.045
regulation of secretion GO:0051046 274 0.044
carbohydrate transport GO:0008643 62 0.044
regulation of cellular amine metabolic process GO:0033238 20 0.044
epithelial cell proliferation GO:0050673 174 0.043
negative regulation of t cell activation GO:0050868 65 0.043
positive regulation of cellular amine metabolic process GO:0033240 5 0.041
organic hydroxy compound metabolic process GO:1901615 203 0.040
endocrine process GO:0050886 39 0.039
cellular homeostasis GO:0019725 240 0.038
regulation of lymphocyte activation GO:0051249 240 0.038
cytokine production GO:0001816 319 0.038
cation homeostasis GO:0055080 212 0.036
regulation of protein transport GO:0051223 163 0.035
cellular ion homeostasis GO:0006873 165 0.035
regulation of secretion by cell GO:1903530 249 0.035
peptide hormone secretion GO:0030072 109 0.034
positive regulation of inflammatory response GO:0050729 47 0.034
cell activation involved in immune response GO:0002263 126 0.034
regulation of inflammatory response GO:0050727 147 0.034
regulation of renal sodium excretion GO:0035813 3 0.033
regulation of protein localization GO:0032880 231 0.032
regulation of leukocyte differentiation GO:1902105 159 0.032
regulation of t cell activation GO:0050863 170 0.032
regulation of action potential GO:0098900 4 0.032
cellular amino acid metabolic process GO:0006520 103 0.032
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.032
heart contraction GO:0060047 93 0.032
inorganic ion transmembrane transport GO:0098660 234 0.031
lymphocyte differentiation GO:0030098 242 0.031
b cell activation involved in immune response GO:0002312 50 0.030
cellular response to cytokine stimulus GO:0071345 189 0.030
odontogenesis GO:0042476 78 0.029
nucleoside phosphate biosynthetic process GO:1901293 79 0.029
ribose phosphate biosynthetic process GO:0046390 59 0.029
engulfment of apoptotic cell GO:0043652 3 0.028
purine containing compound metabolic process GO:0072521 311 0.028
positive regulation of defense response GO:0031349 124 0.028
regulation of epithelial cell proliferation GO:0050678 141 0.028
purine containing compound biosynthetic process GO:0072522 70 0.027
urogenital system development GO:0001655 261 0.027
ras protein signal transduction GO:0007265 77 0.027
positive regulation of ion transport GO:0043270 65 0.026
regulation of ion transport GO:0043269 215 0.026
extrinsic apoptotic signaling pathway GO:0097191 126 0.026
regulation of thyroid hormone generation GO:2000609 4 0.026
temperature homeostasis GO:0001659 26 0.025
cell division GO:0051301 120 0.025
immune effector process GO:0002252 321 0.025
renal sodium excretion GO:0035812 3 0.025
cellular amide metabolic process GO:0043603 58 0.025
cation transmembrane transport GO:0098655 266 0.025
nucleotide metabolic process GO:0009117 332 0.025
regulation of interleukin 13 secretion GO:2000665 2 0.025
monosaccharide transport GO:0015749 58 0.024
transmembrane transport GO:0055085 412 0.024
regulation of defense response GO:0031347 233 0.024
mature dendritic cell differentiation GO:0097029 3 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
odontogenesis of dentin containing tooth GO:0042475 66 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
regulation of acute inflammatory response to non antigenic stimulus GO:0002877 2 0.024
response to organonitrogen compound GO:0010243 246 0.024
positive regulation of nucleotide metabolic process GO:0045981 114 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
b cell activation GO:0042113 161 0.023
positive regulation of mapk cascade GO:0043410 170 0.023
glial cell differentiation GO:0010001 131 0.023
oxidation reduction process GO:0055114 342 0.023
inorganic cation transmembrane transport GO:0098662 207 0.022
regulation of cell activation GO:0050865 289 0.022
regulation of cell division GO:0051302 76 0.022
monovalent inorganic cation homeostasis GO:0055067 33 0.022
second messenger mediated signaling GO:0019932 73 0.022
t cell activation GO:0042110 289 0.022
cell differentiation involved in embryonic placenta development GO:0060706 26 0.021
peptidyl tyrosine modification GO:0018212 145 0.021
interleukin 12 secretion GO:0072610 3 0.021
muscle tissue development GO:0060537 308 0.021
regulation of heart rate GO:0002027 36 0.021
myeloid cell differentiation GO:0030099 233 0.021
purine nucleotide biosynthetic process GO:0006164 65 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
regulation of body fluid levels GO:0050878 162 0.020
wnt signaling pathway GO:0016055 188 0.020
myeloid leukocyte differentiation GO:0002573 119 0.020
hexose transport GO:0008645 56 0.020
regulation of fat cell differentiation GO:0045598 81 0.020
corticotropin releasing hormone secretion GO:0043396 2 0.020
cyclic nucleotide biosynthetic process GO:0009190 44 0.020
production of molecular mediator of immune response GO:0002440 103 0.019
norepinephrine transport GO:0015874 2 0.019
protein localization to organelle GO:0033365 185 0.019
circulatory system process GO:0003013 197 0.019
cation transport GO:0006812 399 0.019
regulation of immunological synapse formation GO:2000520 2 0.019
protein localization to nucleus GO:0034504 121 0.019
regulation of blood pressure GO:0008217 93 0.019
negative regulation of immune system process GO:0002683 209 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
interspecies interaction between organisms GO:0044419 83 0.019
regulation of system process GO:0044057 200 0.018
cellular divalent inorganic cation homeostasis GO:0072503 127 0.018
small molecule biosynthetic process GO:0044283 132 0.018
norepinephrine secretion GO:0048243 2 0.018
sensory perception GO:0007600 245 0.018
positive regulation of cytokine production GO:0001819 174 0.018
regulation of ph GO:0006885 26 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.017
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.017
regulation of production of molecular mediator of immune response GO:0002700 65 0.017
multicellular organismal signaling GO:0035637 91 0.017
natural killer cell activation involved in immune response GO:0002323 10 0.017
type 2 immune response GO:0042092 23 0.017
macromolecule catabolic process GO:0009057 281 0.017
negative regulation of inflammatory response GO:0050728 61 0.017
phenol containing compound metabolic process GO:0018958 60 0.017
cyclic purine nucleotide metabolic process GO:0052652 43 0.017
regulation of epidermal cell differentiation GO:0045604 21 0.017
protein maturation GO:0051604 176 0.017
regulation of t helper 2 cell cytokine production GO:2000551 3 0.017
biomineral tissue development GO:0031214 64 0.017
negative regulation of lymphocyte activation GO:0051250 91 0.017
regulation of lymphocyte differentiation GO:0045619 107 0.016
negative regulation of secretion GO:0051048 61 0.016
cellular lipid metabolic process GO:0044255 323 0.016
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
transepithelial chloride transport GO:0030321 4 0.016
multicellular organismal water homeostasis GO:0050891 23 0.016
regulation of keratinocyte differentiation GO:0045616 11 0.016
respiratory gaseous exchange GO:0007585 43 0.016
b cell differentiation GO:0030183 78 0.016
negative regulation of lyase activity GO:0051350 1 0.016
regulation of neuron differentiation GO:0045664 281 0.016
negative regulation of myoblast differentiation GO:0045662 18 0.016
regulation of saliva secretion GO:0046877 2 0.016
neuron migration GO:0001764 122 0.015
protein catabolic process GO:0030163 221 0.015
naphthalene containing compound metabolic process GO:0090420 1 0.015
metal ion homeostasis GO:0055065 189 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.015
negative regulation of secretion by cell GO:1903531 54 0.015
homeostasis of number of cells GO:0048872 210 0.015
cytokine secretion GO:0050663 72 0.015
regulation of muscle tissue development GO:1901861 97 0.015
multi multicellular organism process GO:0044706 109 0.015
positive regulation of t cell costimulation GO:2000525 2 0.014
leukocyte mediated immunity GO:0002443 174 0.014
blood circulation GO:0008015 195 0.014
hormone metabolic process GO:0042445 86 0.014
negative regulation of interleukin 13 production GO:0032696 2 0.014
divalent metal ion transport GO:0070838 172 0.014
adiponectin secretion GO:0070162 2 0.014
positive regulation of cellular ph reduction GO:0032849 2 0.014
mitotic cell cycle process GO:1903047 159 0.014
lipid catabolic process GO:0016042 69 0.014
positive regulation of steroid hormone secretion GO:2000833 2 0.014
regulation of engulfment of apoptotic cell GO:1901074 2 0.014
peptidyl amino acid modification GO:0018193 336 0.014
regulation of heart contraction GO:0008016 77 0.014
retina development in camera type eye GO:0060041 119 0.014
organ growth GO:0035265 117 0.014
synaptic transmission GO:0007268 329 0.014
negative regulation of leukocyte differentiation GO:1902106 51 0.014
camp biosynthetic process GO:0006171 31 0.014
gliogenesis GO:0042063 141 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
negative regulation of myeloid cell differentiation GO:0045638 38 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
histamine induced gastric acid secretion GO:0001697 1 0.014
defense response to other organism GO:0098542 197 0.014
small molecule catabolic process GO:0044282 71 0.014
positive regulation of secretion GO:0051047 130 0.013
negative regulation of epithelial cell proliferation GO:0050680 64 0.013
ribonucleotide biosynthetic process GO:0009260 59 0.013
spermatogenesis GO:0007283 284 0.013
adaptive immune response GO:0002250 155 0.013
regulation of striated muscle cell differentiation GO:0051153 81 0.013
myeloid leukocyte migration GO:0097529 57 0.013
regulation of transmembrane transport GO:0034762 128 0.013
interleukin 13 secretion GO:0072611 2 0.013
regulation of myeloid leukocyte differentiation GO:0002761 58 0.013
response to insulin GO:0032868 100 0.013
regulation of homeostatic process GO:0032844 182 0.013
defense response to virus GO:0051607 68 0.013
entry into other organism involved in symbiotic interaction GO:0051828 15 0.013
sensory perception of chemical stimulus GO:0007606 51 0.013
regulation of lipid transport GO:0032368 36 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.013
regulation of norepinephrine secretion GO:0014061 2 0.013
regulation of cell cycle GO:0051726 281 0.013
divalent inorganic cation transport GO:0072511 178 0.013
catecholamine secretion GO:0050432 15 0.013
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.013
thrombin receptor signaling pathway GO:0070493 2 0.013
blood coagulation GO:0007596 76 0.013
regulation of hormone secretion GO:0046883 88 0.013
gastrin induced gastric acid secretion GO:0001698 1 0.013
ion transmembrane transport GO:0034220 361 0.013
locomotory behavior GO:0007626 195 0.013
eosinophil activation GO:0043307 1 0.013
acid secretion GO:0046717 33 0.013
regulation of kinase activity GO:0043549 249 0.013
negative regulation of cell migration GO:0030336 59 0.013
regulation of sodium ion transport GO:0002028 29 0.012
regulation of mapk cascade GO:0043408 248 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
positive regulation of t cell activation GO:0050870 101 0.012
response to lipopolysaccharide GO:0032496 128 0.012
sodium ion transport GO:0006814 73 0.012
lipid biosynthetic process GO:0008610 179 0.012
negative regulation of protein transport GO:0051224 46 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
catecholamine transport GO:0051937 21 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
phospholipid metabolic process GO:0006644 87 0.012
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
regulation of multi organism process GO:0043900 111 0.012
positive regulation of cell death GO:0010942 224 0.012
hormone secretion GO:0046879 128 0.012
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.012
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
intracellular protein transport GO:0006886 204 0.012
regulation of adaptive immune response GO:0002819 90 0.012
calcium ion transport GO:0006816 159 0.012
anatomical structure homeostasis GO:0060249 145 0.012
vasodilation GO:0042311 28 0.012
cardiac septum development GO:0003279 59 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
positive regulation of chemokine production GO:0032722 22 0.012
regulation of corticotropin releasing hormone secretion GO:0043397 2 0.012
regulation of circadian sleep wake cycle GO:0042749 3 0.012
cellular response to acid chemical GO:0071229 68 0.012
leukocyte proliferation GO:0070661 172 0.012
antibacterial peptide biosynthetic process GO:0002780 2 0.012
negative regulation of response to wounding GO:1903035 77 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
regulation of interleukin 5 secretion GO:2000662 2 0.011
ribose phosphate metabolic process GO:0019693 291 0.011
regulation of alpha beta t cell activation GO:0046634 53 0.011
carboxylic acid catabolic process GO:0046395 51 0.011
regulation of type 2 immune response GO:0002828 18 0.011
regulation of t cell differentiation GO:0045580 83 0.011
regulation of metal ion transport GO:0010959 106 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
negative regulation of multi organism process GO:0043901 68 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
regulation of circadian rhythm GO:0042752 58 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
eosinophil degranulation GO:0043308 1 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.011
single organism nuclear import GO:1902593 95 0.011
regulation of epidermis development GO:0045682 33 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
muscle contraction GO:0006936 101 0.011
protein import GO:0017038 101 0.011
muscle cell differentiation GO:0042692 261 0.011
positive regulation of transferase activity GO:0051347 167 0.011
negative regulation of t cell cytokine production GO:0002725 1 0.011
bone development GO:0060348 120 0.011
negative regulation of nervous system development GO:0051961 156 0.010
g protein coupled receptor internalization GO:0002031 3 0.010
cellular nitrogen compound catabolic process GO:0044270 280 0.010
sensitization GO:0046960 2 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010
positive regulation of vasoconstriction GO:0045907 4 0.010
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
positive regulation of cell activation GO:0050867 158 0.010
positive regulation of nervous system development GO:0051962 221 0.010
endocrine hormone secretion GO:0060986 15 0.010
lymphocyte proliferation GO:0046651 164 0.010
positive regulation of cell motility GO:2000147 116 0.010
viral process GO:0016032 41 0.010
t cell activation involved in immune response GO:0002286 43 0.010
epidermis development GO:0008544 187 0.010
regulation of peptide hormone secretion GO:0090276 75 0.010
dopamine receptor signaling pathway GO:0007212 16 0.010
positive regulation of nucleoside metabolic process GO:0045979 91 0.010
dephosphorylation GO:0016311 129 0.010
alpha beta t cell activation GO:0046631 91 0.010
fat soluble vitamin biosynthetic process GO:0042362 4 0.010
renal tubular secretion GO:0097254 2 0.010
protein secretion GO:0009306 111 0.010
regulation of receptor activity GO:0010469 41 0.010
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.010
regulation of lipid metabolic process GO:0019216 118 0.010

Sprr2d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org