Mus musculus

0 known processes

Oplah

5-oxoprolinase (ATP-hydrolysing)

(Aliases: MGC28663,MGC36824,1700010G02Rik)

Oplah biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid metabolic process GO:0032787 191 0.122
regulation of cellular ketone metabolic process GO:0010565 66 0.121
oxidation reduction process GO:0055114 342 0.111
cellular amino acid metabolic process GO:0006520 103 0.102
nucleoside phosphate metabolic process GO:0006753 338 0.088
nucleobase containing small molecule metabolic process GO:0055086 352 0.088
regulation of cellular amino acid metabolic process GO:0006521 5 0.080
cellular ketone metabolic process GO:0042180 84 0.074
cellular lipid metabolic process GO:0044255 323 0.071
purine ribonucleotide metabolic process GO:0009150 290 0.066
nucleotide metabolic process GO:0009117 332 0.066
fatty acid metabolic process GO:0006631 121 0.059
amine metabolic process GO:0009308 45 0.058
cellular nitrogen compound catabolic process GO:0044270 280 0.056
regulation of cellular amine metabolic process GO:0033238 20 0.054
cellular amine metabolic process GO:0044106 44 0.052
ras protein signal transduction GO:0007265 77 0.050
purine containing compound metabolic process GO:0072521 311 0.049
small molecule catabolic process GO:0044282 71 0.049
regulation of hormone levels GO:0010817 211 0.043
aromatic compound catabolic process GO:0019439 286 0.042
lipid biosynthetic process GO:0008610 179 0.042
purine nucleotide metabolic process GO:0006163 302 0.042
ribonucleotide metabolic process GO:0009259 291 0.042
small gtpase mediated signal transduction GO:0007264 97 0.041
lipid catabolic process GO:0016042 69 0.040
organic anion transport GO:0015711 137 0.040
cation homeostasis GO:0055080 212 0.039
organic hydroxy compound metabolic process GO:1901615 203 0.039
nucleoside phosphate catabolic process GO:1901292 222 0.038
anion transport GO:0006820 177 0.038
glycosyl compound metabolic process GO:1901657 246 0.038
negative regulation of cellular protein metabolic process GO:0032269 247 0.038
nucleoside metabolic process GO:0009116 246 0.038
cation transport GO:0006812 399 0.037
purine nucleoside catabolic process GO:0006152 205 0.037
purine nucleoside metabolic process GO:0042278 241 0.036
monocarboxylic acid catabolic process GO:0072329 27 0.036
ribonucleoside metabolic process GO:0009119 245 0.036
organic cyclic compound catabolic process GO:1901361 295 0.036
regulation of hydrolase activity GO:0051336 246 0.035
coenzyme metabolic process GO:0006732 52 0.035
ribonucleotide catabolic process GO:0009261 208 0.034
organic acid catabolic process GO:0016054 51 0.034
metal ion homeostasis GO:0055065 189 0.034
organophosphate catabolic process GO:0046434 232 0.034
cellular homeostasis GO:0019725 240 0.034
cellular lipid catabolic process GO:0044242 52 0.033
fatty acid oxidation GO:0019395 28 0.033
very long chain fatty acid catabolic process GO:0042760 2 0.033
nucleotide catabolic process GO:0009166 217 0.033
nitrogen compound transport GO:0071705 271 0.033
carbohydrate metabolic process GO:0005975 230 0.033
regulation of secretion GO:0051046 274 0.032
transmembrane transport GO:0055085 412 0.032
carboxylic acid catabolic process GO:0046395 51 0.032
regulation of lipid metabolic process GO:0019216 118 0.031
ribose phosphate metabolic process GO:0019693 291 0.031
cellular chemical homeostasis GO:0055082 215 0.031
heterocycle catabolic process GO:0046700 280 0.031
lipid modification GO:0030258 65 0.030
organic acid biosynthetic process GO:0016053 86 0.030
purine containing compound catabolic process GO:0072523 213 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.030
glycosyl compound catabolic process GO:1901658 206 0.029
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
maintenance of location GO:0051235 89 0.028
ion transmembrane transport GO:0034220 361 0.028
dephosphorylation GO:0016311 129 0.028
membrane organization GO:0061024 245 0.028
regulation of cellular catabolic process GO:0031329 242 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
cytokine production GO:0001816 319 0.027
nucleoside triphosphate metabolic process GO:0009141 230 0.027
reactive nitrogen species metabolic process GO:2001057 0 0.027
cofactor metabolic process GO:0051186 80 0.026
regulation of fatty acid metabolic process GO:0019217 28 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
immune effector process GO:0002252 321 0.026
peptidyl amino acid modification GO:0018193 336 0.025
lipid localization GO:0010876 126 0.025
multicellular organism growth GO:0035264 161 0.025
small molecule biosynthetic process GO:0044283 132 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
organonitrogen compound catabolic process GO:1901565 264 0.025
response to extracellular stimulus GO:0009991 127 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
organic acid transport GO:0015849 101 0.024
regulation of organelle organization GO:0033043 289 0.024
multicellular organismal homeostasis GO:0048871 164 0.023
regulation of kinase activity GO:0043549 249 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
lipid oxidation GO:0034440 29 0.022
purine nucleotide catabolic process GO:0006195 211 0.022
cell type specific apoptotic process GO:0097285 268 0.022
ribonucleoside catabolic process GO:0042454 206 0.022
negative regulation of molecular function GO:0044092 258 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
positive regulation of protein modification process GO:0031401 299 0.022
regulation of membrane potential GO:0042391 192 0.022
glucose homeostasis GO:0042593 128 0.022
nucleoside catabolic process GO:0009164 206 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
regulation of cytokine production GO:0001817 266 0.022
regulation of defense response GO:0031347 233 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
carboxylic acid transport GO:0046942 100 0.021
microtubule based process GO:0007017 236 0.021
axonogenesis GO:0007409 274 0.021
cation transmembrane transport GO:0098655 266 0.021
germ cell development GO:0007281 185 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
cellular ion homeostasis GO:0006873 165 0.021
response to organonitrogen compound GO:0010243 246 0.020
acyl coa metabolic process GO:0006637 19 0.020
skeletal system development GO:0001501 356 0.020
actin cytoskeleton organization GO:0030036 220 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
protein maturation GO:0051604 176 0.020
regulation of neuron differentiation GO:0045664 281 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
regulation of fatty acid oxidation GO:0046320 10 0.019
fat cell differentiation GO:0045444 160 0.019
regulation of cell projection organization GO:0031344 206 0.019
monocarboxylic acid biosynthetic process GO:0072330 61 0.019
protein catabolic process GO:0030163 221 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
regulation of cell cycle GO:0051726 281 0.018
regulation of homeostatic process GO:0032844 182 0.018
spermatogenesis GO:0007283 284 0.018
hormone secretion GO:0046879 128 0.018
amide transport GO:0042886 138 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.018
apoptotic signaling pathway GO:0097190 306 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
anion transmembrane transport GO:0098656 71 0.018
glucose metabolic process GO:0006006 92 0.018
regulation of secretion by cell GO:1903530 249 0.018
neuron death GO:0070997 154 0.018
regulation of response to wounding GO:1903034 189 0.018
regulation of nucleoside metabolic process GO:0009118 130 0.018
regulation of nucleotide metabolic process GO:0006140 169 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
steroid metabolic process GO:0008202 119 0.017
organelle fission GO:0048285 170 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
male gamete generation GO:0048232 285 0.017
intracellular protein transport GO:0006886 204 0.017
inflammatory response GO:0006954 244 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
monosaccharide metabolic process GO:0005996 106 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
alcohol metabolic process GO:0006066 116 0.017
negative regulation of neuron differentiation GO:0045665 101 0.017
leukocyte differentiation GO:0002521 342 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
myeloid cell differentiation GO:0030099 233 0.016
mitochondrion organization GO:0007005 134 0.016
cholesterol metabolic process GO:0008203 56 0.016
peptide secretion GO:0002790 114 0.016
innate immune response GO:0045087 157 0.016
response to peptide GO:1901652 136 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
lipid transport GO:0006869 98 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
carbohydrate homeostasis GO:0033500 128 0.016
endomembrane system organization GO:0010256 147 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.015
thioester metabolic process GO:0035383 19 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
regulation of neuron projection development GO:0010975 169 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
regulation of ras protein signal transduction GO:0046578 114 0.015
endocytosis GO:0006897 168 0.015
sensory perception GO:0007600 245 0.015
regulation of lipid biosynthetic process GO:0046890 54 0.015
carbohydrate biosynthetic process GO:0016051 74 0.015
regulation of peptide secretion GO:0002791 77 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
generation of precursor metabolites and energy GO:0006091 103 0.015
t cell activation GO:0042110 289 0.015
response to peptide hormone GO:0043434 127 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
cytokine mediated signaling pathway GO:0019221 115 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
cell activation involved in immune response GO:0002263 126 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
cell adhesion GO:0007155 329 0.015
spermatid development GO:0007286 108 0.015
peptide transport GO:0015833 133 0.014
sulfur compound biosynthetic process GO:0044272 37 0.014
dna metabolic process GO:0006259 303 0.014
chromatin modification GO:0016568 187 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
regulation of neuron death GO:1901214 134 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
circulatory system process GO:0003013 197 0.014
synaptic transmission GO:0007268 329 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
glucan metabolic process GO:0044042 32 0.014
positive regulation of fatty acid oxidation GO:0046321 4 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
regulation of cell activation GO:0050865 289 0.014
cytoplasmic transport GO:0016482 234 0.014
gland development GO:0048732 330 0.014
mitotic cell cycle GO:0000278 195 0.014
fatty acid biosynthetic process GO:0006633 41 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
macromolecule catabolic process GO:0009057 281 0.014
negative regulation of protein modification process GO:0031400 163 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
leukocyte mediated immunity GO:0002443 174 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
regulation of transferase activity GO:0051338 263 0.013
regulation of inflammatory response GO:0050727 147 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
glycerolipid metabolic process GO:0046486 122 0.013
regulation of cholesterol metabolic process GO:0090181 14 0.013
protein processing GO:0016485 163 0.013
positive regulation of cytokine production GO:0001819 174 0.013
mitotic cell cycle process GO:1903047 159 0.013
alpha amino acid metabolic process GO:1901605 59 0.013
positive regulation of cell development GO:0010720 237 0.013
cognition GO:0050890 149 0.013
chromatin organization GO:0006325 206 0.013
regulation of system process GO:0044057 200 0.013
forebrain development GO:0030900 302 0.013
protein localization to organelle GO:0033365 185 0.013
neutral lipid metabolic process GO:0006638 57 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
positive regulation of cell death GO:0010942 224 0.013
protein localization to membrane GO:0072657 108 0.013
response to organic cyclic compound GO:0014070 198 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
muscle tissue development GO:0060537 308 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
peptide hormone secretion GO:0030072 109 0.013
response to nutrient levels GO:0031667 109 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
organic hydroxy compound biosynthetic process GO:1901617 77 0.013
sulfur compound metabolic process GO:0006790 100 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
regulation of binding GO:0051098 111 0.012
negative regulation of cell development GO:0010721 169 0.012
cellular response to lipid GO:0071396 145 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
regulation of cellular response to stress GO:0080135 159 0.012
positive regulation of immune effector process GO:0002699 107 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
mapk cascade GO:0000165 281 0.012
cell killing GO:0001906 67 0.012
lateral inhibition GO:0046331 1 0.012
regulation of anatomical structure size GO:0090066 178 0.012
rho protein signal transduction GO:0007266 32 0.012
regulation of intracellular transport GO:0032386 159 0.012
striated muscle tissue development GO:0014706 293 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
gtp metabolic process GO:0046039 144 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
negative regulation of lipid metabolic process GO:0045833 30 0.012
ribonucleoside bisphosphate metabolic process GO:0033875 9 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
positive regulation of growth GO:0045927 104 0.012
response to acid chemical GO:0001101 111 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
chemotaxis GO:0006935 247 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.012
regulation of protein localization GO:0032880 231 0.012
renal system development GO:0072001 225 0.012
negative regulation of nervous system development GO:0051961 156 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
response to insulin GO:0032868 100 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
regulation of mapk cascade GO:0043408 248 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
multi multicellular organism process GO:0044706 109 0.011
amino acid transport GO:0006865 61 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
blood vessel morphogenesis GO:0048514 285 0.011
plasma membrane organization GO:0007009 90 0.011
regulation of ion transport GO:0043269 215 0.011
neuron apoptotic process GO:0051402 142 0.011
epithelial cell development GO:0002064 159 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
sterol metabolic process GO:0016125 58 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
adult behavior GO:0030534 135 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
monocarboxylic acid transport GO:0015718 44 0.011
cellular modified amino acid metabolic process GO:0006575 63 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
regulation of fatty acid biosynthetic process GO:0042304 12 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.011
methylation GO:0032259 134 0.011
learning or memory GO:0007611 148 0.011
regulation of protein transport GO:0051223 163 0.011
organelle localization GO:0051640 179 0.011
response to light stimulus GO:0009416 135 0.011
glycogen metabolic process GO:0005977 32 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
lung development GO:0030324 164 0.010
cellular response to external stimulus GO:0071496 88 0.010
central nervous system neuron differentiation GO:0021953 162 0.010
regulation of protein processing GO:0070613 96 0.010
gtp catabolic process GO:0006184 143 0.010
regulation of proteolysis GO:0030162 164 0.010
hormone metabolic process GO:0042445 86 0.010
protein ubiquitination GO:0016567 171 0.010
hematopoietic stem cell migration GO:0035701 1 0.010
positive regulation of gtpase activity GO:0043547 85 0.010
regulation of purine nucleotide catabolic process GO:0033121 122 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
muscle system process GO:0003012 141 0.010
cellular alcohol metabolic process GO:0044107 3 0.010
ossification GO:0001503 216 0.010
organic hydroxy compound transport GO:0015850 93 0.010
positive regulation of secretion by cell GO:1903532 114 0.010
cellular response to acid chemical GO:0071229 68 0.010
regulation of t cell activation GO:0050863 170 0.010
cellularization GO:0007349 1 0.010
regulation of cell cycle process GO:0010564 160 0.010
circadian rhythm GO:0007623 114 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
protein targeting GO:0006605 143 0.010
hexose metabolic process GO:0019318 98 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
regulation of ras gtpase activity GO:0032318 88 0.010
polysaccharide metabolic process GO:0005976 39 0.010
energy derivation by oxidation of organic compounds GO:0015980 77 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
negative regulation of proteolysis GO:0045861 74 0.010

Oplah disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
central nervous system disease DOID:331 0 0.013
sensory system disease DOID:0050155 0 0.010