Mus musculus

37 known processes

Map3k12

mitogen-activated protein kinase kinase kinase 12

(Aliases: DLK,Zpk,MUK)

Map3k12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of membrane potential GO:0042391 192 0.122
transmembrane transport GO:0055085 412 0.099
ion transmembrane transport GO:0034220 361 0.097
apoptotic signaling pathway GO:0097190 306 0.080
regulation of kinase activity GO:0043549 249 0.080
Worm
regulation of postsynaptic membrane potential GO:0060078 48 0.065
membrane depolarization GO:0051899 64 0.063
intrinsic apoptotic signaling pathway GO:0097193 132 0.057
cellular ketone metabolic process GO:0042180 84 0.056
regulation of cellular catabolic process GO:0031329 242 0.056
negative regulation of molecular function GO:0044092 258 0.054
anion transport GO:0006820 177 0.054
cytoplasmic transport GO:0016482 234 0.053
synaptic transmission GO:0007268 329 0.045
Worm Fly
regulation of actin filament based process GO:0032970 99 0.043
nitrogen compound transport GO:0071705 271 0.043
regulation of protein serine threonine kinase activity GO:0071900 157 0.042
Worm
muscle tissue development GO:0060537 308 0.042
negative regulation of phosphate metabolic process GO:0045936 184 0.041
positive regulation of kinase activity GO:0033674 155 0.041
Worm
dna repair GO:0006281 107 0.039
nucleotide metabolic process GO:0009117 332 0.039
regulation of protein kinase activity GO:0045859 232 0.039
Worm
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
positive regulation of protein phosphorylation GO:0001934 242 0.037
Worm
male gamete generation GO:0048232 285 0.035
Fly
neuron neuron synaptic transmission GO:0007270 69 0.035
macromolecule catabolic process GO:0009057 281 0.034
regulation of apoptotic signaling pathway GO:2001233 197 0.034
multicellular organismal response to stress GO:0033555 62 0.034
negative regulation of protein metabolic process GO:0051248 282 0.034
lipid transport GO:0006869 98 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.033
regulation of secretion GO:0051046 274 0.032
respiratory system development GO:0060541 190 0.032
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.032
regulation of transmembrane transport GO:0034762 128 0.032
organic anion transport GO:0015711 137 0.032
regulation of stress activated mapk cascade GO:0032872 69 0.032
lung development GO:0030324 164 0.032
negative regulation of phosphorylation GO:0042326 166 0.032
organelle localization GO:0051640 179 0.031
dna metabolic process GO:0006259 303 0.031
protein modification by small protein conjugation GO:0032446 187 0.031
regulation of jnk cascade GO:0046328 62 0.031
endomembrane system organization GO:0010256 147 0.031
Fly
cellular nitrogen compound catabolic process GO:0044270 280 0.031
protein localization to organelle GO:0033365 185 0.031
learning or memory GO:0007611 148 0.031
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.031
exocytosis GO:0006887 121 0.031
nucleoside metabolic process GO:0009116 246 0.031
actin cytoskeleton organization GO:0030036 220 0.030
vesicle localization GO:0051648 86 0.030
cytoskeleton dependent intracellular transport GO:0030705 50 0.030
regulation of cellular response to stress GO:0080135 159 0.030
cell adhesion GO:0007155 329 0.029
leukocyte differentiation GO:0002521 342 0.029
multicellular organismal signaling GO:0035637 91 0.029
regulation of ion transport GO:0043269 215 0.029
intracellular protein transport GO:0006886 204 0.029
jnk cascade GO:0007254 72 0.029
regulation of organelle organization GO:0033043 289 0.029
homeostasis of number of cells GO:0048872 210 0.028
regulation of cytoskeleton organization GO:0051493 122 0.028
stem cell proliferation GO:0072089 117 0.028
microtubule based transport GO:0010970 50 0.028
regulation of hydrolase activity GO:0051336 246 0.027
aromatic compound catabolic process GO:0019439 286 0.027
establishment of organelle localization GO:0051656 122 0.027
axon cargo transport GO:0008088 33 0.027
regulation of transferase activity GO:0051338 263 0.027
Worm
amine metabolic process GO:0009308 45 0.027
fat cell differentiation GO:0045444 160 0.027
protein targeting GO:0006605 143 0.027
mitotic cell cycle GO:0000278 195 0.027
protein import GO:0017038 101 0.026
negative regulation of transferase activity GO:0051348 85 0.026
protein polymerization GO:0051258 57 0.026
nuclear division GO:0000280 158 0.026
stress activated mapk cascade GO:0051403 80 0.026
heterocycle catabolic process GO:0046700 280 0.026
negative regulation of protein modification process GO:0031400 163 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.025
nucleocytoplasmic transport GO:0006913 139 0.025
meiotic cell cycle GO:0051321 122 0.025
positive regulation of nervous system development GO:0051962 221 0.025
blood circulation GO:0008015 195 0.025
negative regulation of jun kinase activity GO:0043508 9 0.025
cellular response to dna damage stimulus GO:0006974 207 0.024
hormone secretion GO:0046879 128 0.024
regulation of hormone levels GO:0010817 211 0.024
ossification GO:0001503 216 0.024
protein import into nucleus GO:0006606 95 0.024
fear response GO:0042596 33 0.024
peptide transport GO:0015833 133 0.024
response to amino acid GO:0043200 37 0.024
carbohydrate derivative biosynthetic process GO:1901137 183 0.024
myeloid cell differentiation GO:0030099 233 0.024
gland development GO:0048732 330 0.023
stem cell maintenance GO:0019827 130 0.023
response to organonitrogen compound GO:0010243 246 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.023
neuronal action potential GO:0019228 54 0.023
peptide hormone secretion GO:0030072 109 0.023
purine nucleotide catabolic process GO:0006195 211 0.023
skeletal system development GO:0001501 356 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
spermatogenesis GO:0007283 284 0.022
Fly
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
steroid metabolic process GO:0008202 119 0.022
divalent inorganic cation transport GO:0072511 178 0.022
wnt signaling pathway GO:0016055 188 0.022
stress activated protein kinase signaling cascade GO:0031098 81 0.022
negative regulation of protein phosphorylation GO:0001933 126 0.022
synaptic vesicle transport GO:0048489 57 0.022
regulation of receptor activity GO:0010469 41 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
organic cyclic compound catabolic process GO:1901361 295 0.021
multicellular organism growth GO:0035264 161 0.021
digestive system development GO:0055123 200 0.021
negative regulation of phosphorus metabolic process GO:0010563 184 0.021
microtubule based process GO:0007017 236 0.021
positive regulation of homeostatic process GO:0032846 64 0.021
glycoprotein metabolic process GO:0009100 116 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
defecation GO:0030421 1 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
behavioral fear response GO:0001662 28 0.021
connective tissue development GO:0061448 179 0.021
cellular lipid metabolic process GO:0044255 323 0.021
regulation of map kinase activity GO:0043405 120 0.021
Worm
translation GO:0006412 93 0.021
regulation of cell cycle GO:0051726 281 0.020
purine containing compound metabolic process GO:0072521 311 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
regulation of actin cytoskeleton organization GO:0032956 84 0.020
nucleoside catabolic process GO:0009164 206 0.020
regulation of homeostatic process GO:0032844 182 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
axonogenesis GO:0007409 274 0.020
Fly
embryonic placenta development GO:0001892 98 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
leukocyte migration GO:0050900 124 0.020
regulation of establishment of protein localization GO:0070201 181 0.019
learning GO:0007612 98 0.019
placenta development GO:0001890 140 0.019
digestive tract morphogenesis GO:0048546 147 0.019
response to molecule of bacterial origin GO:0002237 143 0.019
axon transport of mitochondrion GO:0019896 2 0.019
muscle contraction GO:0006936 101 0.019
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.019
regulation of protein catabolic process GO:0042176 108 0.019
membrane organization GO:0061024 245 0.019
forebrain development GO:0030900 302 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
striated muscle tissue development GO:0014706 293 0.019
appendage development GO:0048736 166 0.019
cytokine production GO:0001816 319 0.019
cellular amine metabolic process GO:0044106 44 0.019
actin polymerization or depolymerization GO:0008154 54 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.018
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.018
camera type eye development GO:0043010 266 0.018
regulation of mapk cascade GO:0043408 248 0.018
Worm
multi multicellular organism process GO:0044706 109 0.018
negative regulation of kinase activity GO:0033673 81 0.018
cerebellum morphogenesis GO:0021587 42 0.018
microtubule based movement GO:0007018 84 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
regulation of system process GO:0044057 200 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
Worm
cognition GO:0050890 149 0.018
cellular amino acid metabolic process GO:0006520 103 0.018
oxidation reduction process GO:0055114 342 0.018
cardiac muscle tissue development GO:0048738 130 0.018
establishment of vesicle localization GO:0051650 81 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
sequestering of calcium ion GO:0051208 18 0.018
regulation of secretion by cell GO:1903530 249 0.018
sequestering of metal ion GO:0051238 19 0.018
meiotic nuclear division GO:0007126 115 0.017
regulation of stem cell proliferation GO:0072091 78 0.017
canonical wnt signaling pathway GO:0060070 130 0.017
transmission of nerve impulse GO:0019226 76 0.017
t cell activation GO:0042110 289 0.017
alcohol metabolic process GO:0006066 116 0.017
response to lipopolysaccharide GO:0032496 128 0.017
embryonic limb morphogenesis GO:0030326 126 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
carboxylic acid transport GO:0046942 100 0.017
regulation of cellular ketone metabolic process GO:0010565 66 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
actin filament based movement GO:0030048 23 0.017
mapk cascade GO:0000165 281 0.017
Worm
gastrulation GO:0007369 116 0.017
reactive nitrogen species metabolic process GO:2001057 0 0.017
neurotransmitter secretion GO:0007269 62 0.017
respiratory tube development GO:0030323 167 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
behavioral defense response GO:0002209 28 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
skeletal muscle organ development GO:0060538 163 0.017
regulation of transporter activity GO:0032409 57 0.016
regulation of protein localization GO:0032880 231 0.016
adult locomotory behavior GO:0008344 91 0.016
rna processing GO:0006396 105 0.016
action potential GO:0001508 78 0.016
cellular response to biotic stimulus GO:0071216 92 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
cell type specific apoptotic process GO:0097285 268 0.016
endocytosis GO:0006897 168 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
epidermis development GO:0008544 187 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
cellular response to lipid GO:0071396 145 0.016
determination of left right symmetry GO:0007368 80 0.016
cartilage development GO:0051216 140 0.016
regulation of cell migration GO:0030334 219 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
dna recombination GO:0006310 92 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
nuclear transport GO:0051169 139 0.016
regulation of jun kinase activity GO:0043506 40 0.016
purine containing compound catabolic process GO:0072523 213 0.016
leukocyte proliferation GO:0070661 172 0.015
tissue remodeling GO:0048771 102 0.015
peptide secretion GO:0002790 114 0.015
fertilization GO:0009566 127 0.015
neuron projection guidance GO:0097485 141 0.015
lipid localization GO:0010876 126 0.015
response to radiation GO:0009314 165 0.015
leukocyte mediated immunity GO:0002443 174 0.015
retina development in camera type eye GO:0060041 119 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
carbohydrate homeostasis GO:0033500 128 0.015
protein processing GO:0016485 163 0.015
positive regulation of mapk cascade GO:0043410 170 0.015
Worm
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
anion transmembrane transport GO:0098656 71 0.015
t cell differentiation GO:0030217 174 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
glial cell differentiation GO:0010001 131 0.014
regulation of phospholipase a2 activity GO:0032429 3 0.014
organelle fission GO:0048285 170 0.014
synaptic vesicle localization GO:0097479 59 0.014
positive regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000060 8 0.014
sensory perception GO:0007600 245 0.014
dendrite development GO:0016358 115 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
protein maturation GO:0051604 176 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
protein ubiquitination GO:0016567 171 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
neuromuscular process GO:0050905 99 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
tissue homeostasis GO:0001894 115 0.014
angiogenesis GO:0001525 201 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
rna interference GO:0016246 2 0.014
cell division GO:0051301 120 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
gene silencing GO:0016458 38 0.014
rho protein signal transduction GO:0007266 32 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
macromolecular complex disassembly GO:0032984 43 0.014
negative regulation of cell cycle GO:0045786 123 0.014
mitotic cell cycle process GO:1903047 159 0.014
regulation of leukocyte mediated immunity GO:0002703 104 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
formation of radial glial scaffolds GO:0021943 4 0.013
negative regulation of wnt signaling pathway GO:0030178 73 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
regulation of muscle tissue development GO:1901861 97 0.013
amide transport GO:0042886 138 0.013
nuclear import GO:0051170 95 0.013
adult behavior GO:0030534 135 0.013
gonad development GO:0008406 141 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
regulation of intracellular transport GO:0032386 159 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
genitalia development GO:0048806 37 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
insulin secretion GO:0030073 89 0.013
regulation of striated muscle cell differentiation GO:0051153 81 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
intestinal epithelial structure maintenance GO:0060729 4 0.013
myeloid cell homeostasis GO:0002262 114 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
oligodendrocyte differentiation GO:0048709 53 0.013
kidney development GO:0001822 213 0.013
axon guidance GO:0007411 141 0.013
protein localization to nucleus GO:0034504 121 0.013
cell activation involved in immune response GO:0002263 126 0.013
positive regulation of stem cell proliferation GO:2000648 59 0.013
positive regulation of lipid transport GO:0032370 22 0.013
cellular response to acid chemical GO:0071229 68 0.013
regulation of protein transport GO:0051223 163 0.013
b cell activation GO:0042113 161 0.012
actin mediated cell contraction GO:0070252 15 0.012
maintenance of location GO:0051235 89 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
establishment of synaptic vesicle localization GO:0097480 57 0.012
neural precursor cell proliferation GO:0061351 121 0.012
muscle system process GO:0003012 141 0.012
cardiac cell fate specification GO:0060912 2 0.012
negative regulation of mapk cascade GO:0043409 65 0.012
artery development GO:0060840 53 0.012
chemotaxis GO:0006935 247 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
regulation of cell cycle process GO:0010564 160 0.012
mechanoreceptor differentiation GO:0042490 67 0.012
regulation of cellular component size GO:0032535 121 0.012
regulation of peptide transport GO:0090087 91 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
positive regulation of cytokine production GO:0001819 174 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
regulation of synaptic transmission glutamatergic GO:0051966 19 0.012
regulation of cell activation GO:0050865 289 0.012
limb morphogenesis GO:0035108 149 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
regulation of binding GO:0051098 111 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
skin development GO:0043588 220 0.012
mrna metabolic process GO:0016071 84 0.012
skeletal system morphogenesis GO:0048705 203 0.012
bone mineralization GO:0030282 54 0.012
regulation of ion transmembrane transporter activity GO:0032412 54 0.012
sensory perception of sound GO:0007605 97 0.012
peptidyl amino acid modification GO:0018193 336 0.012
single organism nuclear import GO:1902593 95 0.012
cardiac chamber morphogenesis GO:0003206 93 0.012
positive regulation of stress activated mapk cascade GO:0032874 48 0.012
response to acid chemical GO:0001101 111 0.012
glutamate receptor signaling pathway GO:0007215 35 0.012
wound healing GO:0042060 157 0.012
hindbrain morphogenesis GO:0021575 46 0.012
positive regulation of proteolysis GO:0045862 85 0.012
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 10 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
rhythmic process GO:0048511 174 0.012
protein oligomerization GO:0051259 67 0.012
cardiac muscle contraction GO:0060048 32 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
response to organic cyclic compound GO:0014070 198 0.012
positive regulation of protein transport GO:0051222 93 0.012
plasma membrane organization GO:0007009 90 0.012
telencephalon development GO:0021537 186 0.011
lymphocyte proliferation GO:0046651 164 0.011
spermatid differentiation GO:0048515 115 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
palate development GO:0060021 76 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
actin filament polymerization GO:0030041 44 0.011
reproductive behavior GO:0019098 32 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
regulation of protein ubiquitination GO:0031396 52 0.011
cardiac muscle cell contraction GO:0086003 7 0.011
ear development GO:0043583 200 0.011
protein catabolic process GO:0030163 221 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
lipid biosynthetic process GO:0008610 179 0.011
inflammatory response GO:0006954 244 0.011
cardiac chamber development GO:0003205 108 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
regulation of peptide secretion GO:0002791 77 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
muscle cell differentiation GO:0042692 261 0.011
cellular ion homeostasis GO:0006873 165 0.011
compound eye development GO:0048749 1 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
ras protein signal transduction GO:0007265 77 0.011
regulation of dna binding GO:0051101 39 0.011
carbohydrate metabolic process GO:0005975 230 0.011
regulation of actin polymerization or depolymerization GO:0008064 45 0.011
spermatid development GO:0007286 108 0.011
regulation of anatomical structure size GO:0090066 178 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
germ cell development GO:0007281 185 0.011
positive regulation of cellular protein catabolic process GO:1903364 34 0.011
regulation of ion homeostasis GO:2000021 64 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
protein autophosphorylation GO:0046777 61 0.011
cellular protein complex assembly GO:0043623 116 0.011
positive regulation of transferase activity GO:0051347 167 0.011
Worm
cellular response to ammonium ion GO:0071242 2 0.011
regulation of cellular protein catabolic process GO:1903362 61 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
regulation of protein complex assembly GO:0043254 83 0.010
appendage morphogenesis GO:0035107 149 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
response to monosaccharide GO:0034284 67 0.010
negative regulation of immune system process GO:0002683 209 0.010
positive regulation of protein modification process GO:0031401 299 0.010
Worm
regulation of neuron death GO:1901214 134 0.010
glucose homeostasis GO:0042593 128 0.010
t cell proliferation GO:0042098 120 0.010
cation transmembrane transport GO:0098655 266 0.010
organic acid transport GO:0015849 101 0.010
meiotic cell cycle process GO:1903046 77 0.010
cell maturation GO:0048469 127 0.010
positive regulation of leukocyte mediated immunity GO:0002705 70 0.010
cellular macromolecule catabolic process GO:0044265 206 0.010
negative regulation of fat cell differentiation GO:0045599 36 0.010
multi organism behavior GO:0051705 62 0.010
cellular homeostasis GO:0019725 240 0.010
positive regulation of secretion GO:0051047 130 0.010
positive regulation of cell development GO:0010720 237 0.010
blastocyst development GO:0001824 80 0.010
immune effector process GO:0002252 321 0.010

Map3k12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.072
carbohydrate metabolism disease DOID:0050013 0 0.030
acquired metabolic disease DOID:0060158 0 0.030
glucose metabolism disease DOID:4194 0 0.026
diabetes mellitus DOID:9351 0 0.024
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
type 2 diabetes mellitus DOID:9352 0 0.020
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012
sensory system disease DOID:0050155 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
eye and adnexa disease DOID:1492 0 0.010